Clinical trials: Overall Health
Obesity, Childhood
GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward
The rapid emergence of new and highly effective obesity medications has turned the field of pediatric weight management on its head.
- Trial name
- GLOW (NCT06977438)
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 1,020 people
- Sponsor
- University of Minnesota
Effects of Photographic Aids (Photos of Faces) on Patient Recall of Their Clinical Care Team, Effects of Photographic Aids (Photos of Faces) on Clinician-patient Communication
Put a Face to a Name (Part A): The Effects of Photographic Aids on Patient Satisfaction, Clinician Communication, and Quality of Care
Communication is critical within healthcare, and is the root cause of most errors. With increased adoption and use of new information technologies and mediated communication systems, such as Electronic Health Records (EHR), that…
- Conditions
- Effects of Photographic Aids (Photos of Faces) on Patient Recall of Their Clinical Care Team, Effects of Photographic Aids (Photos of Faces) on Clinician-patient Communication, Effects of Photographic Aids (Photos of Faces) on Overall Patient Satisfaction
- Trial name
- Face2Name (NCT01658644)
- Testing
- Provision of Clinical Care Handout
- Where
- Canada
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Glioblastoma, Glioblastoma Multiforme
The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients.
The trial is designed as a multicenter randomized controlled study. 246 patients with presumed Glioblastoma Multiforme in eloquent areas on diagnostic MRI will be selected by the neurosurgeons according the eligibility criteria…
- Conditions
- Glioblastoma, Glioblastoma Multiforme, Glioblastoma Multiforme of Brain, Astrocytoma, Grade IV
- Trial name
- SAFE (NCT03861299)
- Testing
- Awake craniotomy, Craniotomy under general anesthesia
- Where
- 5 sites in Belgium, Netherlands
- Volunteers
- 246 people
- Sponsor
- Jasper Gerritsen
Sleep, Pain
Radicle Health1: A Study of Health and Wellness Formulations and Their Effects on Overall Health
A randomized, blinded, placebo-controlled study of health and wellness product formulations and their effects on overall health
- Conditions
- Sleep, Pain, Depression, Anxiety
- Trial name
- NCT05783232
- Testing
- Health Active Study Product 1.1 Capsules, Health Active Study Product 1.2 Capsules, Health Active Study Product 1.3 Capsules
- Where
- United States
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Dietary Nitrate Supplementation
Evaluating the Metabolic Effects of Dietary Nitrate Supplementation
Dietary nitrate is found to enhance muscle fatty acid oxidation/glucose uptake and increase mitochondrial biogenesis, which in turn, aid in the prevention and management of metabolic diseases.
- Trial name
- NIMMI (NCT05579262)
- Testing
- Beetroot juice
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Aging, Muscle Strength
Get in Shape in the Team Research: Porukalla Kuntoon Tutkimus
It is well accepted that physical activity in the form of resistance training produces a wide variety of neuromuscular-skeletal and health benefits.
- Trial name
- PoKu (NCT02413112)
- Testing
- Resistance training
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Healthy
Economic Evaluation of Mindline.sg
This study aims to evaluate the effectiveness of mindline.sg, a digital mental health platform, in improving mental health literacy, emotional wellbeing, quality of life, and economic outcomes among adults in Singapore.
- Trial name
- NCT07209904
- Testing
- mindline.sg
- Where
- Singapore
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Centre for Evidence and Implementation Singapore Ltd
HIV
A Clinical Trial in Adult Participants Without HIV and in Overall Good Health to Evaluate the Safety and Immunogenicity of CD4BS CH505M5 Pr-NP1 Followed by CH505 TF chTrimer Boost Both Adjuvanted With Either Lipid Nanoparticles (LNPs) or 3M-052-AF + Alum
This is a multicenter, open-label, phase 1 clinical trial to test two human immunodeficiency virus (HIV) vaccines with two adjuvants.
- Trial name
- NCT06267872
- Testing
- CD4BS CH505M5 Pr-NP1, CH505TF chTrimer, 3M-052-AF (labeled as AP 60-702)
- Where
- 6 sites in United States, South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Head and Neck Cancer
Towards A Better Paradigm for Head and Neck Cancer Treatment Applying Artificial Intelligence. HNC-TACTIC.
This will be an international, multicenter, retrospective, observational, and data-driven study using secondary data captured in EHRs.
- Trial name
- HNC-TACTIC (NCT05117775)
- Testing
- No intervention - Just description and predictive models
- Where
- Spain
- Volunteers
- 10,000 people
- Sponsor
- Savana Research
COVID-19 Patients
Investigating Long-term Health Effects and Complications in COVID-19 Recoveries
Clarify the incidence of functional impairments in cured COVID-19 patients and identify influencing factors. Build a multi-omics database for COVID-19 patients in the recovery period to elucidate the biological biomarkers and…
- Trial name
- NCT06349720
- Testing
- respiratory rehabilitation
- Where
- China
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- Zhaohui Tong
Sleep Quality, Sleep Duration
A Clinical Trial to Evaluate the Effects of a Topical Roll-on and Diffuser Blend on Sleep Quality and Sleep Duration
This study will evaluate the effects of the Saje Sleep Well topical roll-on and the Saje Sleep Well diffuser blend on sleep quality and sleep duration in adults who have experienced issues with sleep quality and sleep duration…
- Conditions
- Sleep Quality, Sleep Duration, Fatigue, Energy Levels
- Trial name
- NCT07779382
- Testing
- Sleep Well Diffuser Blend followed by Sleep Well Roll-On
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saie Beauty
Well-being at Work, Burnout
Emergency Medicine Practitioners Overall Well-being Enhancement With Ambient AI Scribes
The primary objective of the study is to investigate the impact of an ambient AI scribe on clinicians' wellness and well-being outcomes; additionally, the investigators will also explore how the use of the ambient AI scribe will…
- Trial name
- EMPOWER (NCT07742761)
- Testing
- Ambient AI Scribe
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Washington University School of Medicine
Wellbeing, Resilience
Evaluating the Impact of a Digital Psychosocial Tool (Wysa) on Life Skills and Well-being of College Students in India
The goal of this study is to learn the feasibility of a digital psychosocial tool (Wysa) in improving life skills and overall wellbeing of English-speaking college students in IIT-Gandhinagar, a university in India.
- Conditions
- Wellbeing, Resilience, Self Efficacy, Life Skills
- Trial name
- NCT06801093
- Testing
- Digital psychosocial tool
- Where
- India
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Environmental Toxins, General Health
Prospective Human Study Evaluating Changes in Markers of Detoxification, Overall Physical and Mental Health, and Fatigue Following Supplementation With CellCore Protocols
The primary purpose of this study is to evaluate the effects of CellCore protocols on environmental toxicant biomarkers among adult patients with high baseline toxicant levels.
- Trial name
- NCT07753798
- Testing
- CellCore Foundational Protocol, CellCore - BioToxin Binder & Drainage Activator
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- OvationLab
Chronic Severe Pain
A Non-interventional, Observational Study for Quality of Life (Overall Health Assessment) in Patients With Chronic Severe Pain During Targinact® Treatment
This non-interventional, observational study evaluates the efficacy of Targinact with regard to quality of life in daily clinical practice in Belgium compared to the previous analgesic treatment.
- Trial name
- NCT01710917
- Testing
- Targinact® (oxycodon/naloxon)
- Where
- Belgium
- Volunteers
- 1,800 people
- Sponsor
- Mundipharma CVA
Hearing Loss
Evaluation of the Benefits for Overall Health Following Cochlear Implant Treatment in the Elderly Population
The purpose of this study is to show that cochlear implant treatment improves the overall health related quality of life and general well-being in elderly individuals.
- Trial name
- NCT03072862
- Testing
- Commercial Nucleus Cochlear Implant Systems
- Where
- 8 sites in France, Israel and 2 more
- Volunteers
- 100 people
- Sponsor
- Cochlear
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Effects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their Families
Amyotrophic lateral sclerosis (ALS) is a serious rapidly progressive disease of the nervous system. The average survival from the time of diagnosis is two to three years.
- Conditions
- Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Nervous System Diseases, Spinal Cord Diseases
- Trial name
- ALS-LTMV (NCT05744310)
- Testing
- Long term mechanical ventilation support, No long term mechanical ventilation support
- Where
- 9 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Aging, Adults With Overweight and Obesity
Effects of Physical Exercise and a Nutritional Supplement on Body Composition, Metabolic Function, and Overall Health in Adults With a Metabolically Challenging Profile
Early-onset metabolic disturbances (such as mild hyperglycemia, subclinical dyslipidemia, excess body fat, and reduced functional capacity) represent one of the major public health challenges among middle-aged and older adults.
- Conditions
- Aging, Adults With Overweight and Obesity, Supplementation, Exercise
- Trial name
- NCT07504068
- Testing
- Group 1: Exercise + thermogenic supplement (EX-TS)
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- University of Valencia
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Geriatric Care Survivorship Intervention for Improving the Overall Health of Older Adults With Stage I-III Breast Cancer Who Have Completed Curative Treatment
This trial studies the effect of a geriatric care survivorship intervention in improving the overall health of older adults who have completed curative treatment for stage I-III breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- NCT05928325
- Testing
- Comprehensive Geriatric Assessment, Health Education, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center