Clinical trials: Overweight/Obesity
Obesity, Childhood Obesity
The Effects of Integrative Neuromuscular Training on Physical Function in Overweight Children
Childhood obesity is an ongoing and increasing issue, resulting in changes in body mass which cause biomechanical alterations in the lower limbs.
- Trial name
- NCT05724303
- Testing
- 8-week neuromuscular training program
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Obesity
Safety, Tolerability and Pharmacokinetics of Multiple Doses of ZGN-433 in Obese Female Volunteers
The purpose of this study is to assess whether multiple doses of ZGN-433 is safe and well tolerated in obese female subjects. The study will also provide information on how much ZGN-433 gets into the blood, how long does it stay…
- Trial name
- NCT01028261
- Testing
- ZGN-433
- Where
- 2 sites in Australia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Zafgen, Inc.
Childhood Obesity
Brighter Bites - Access, Continuity and Education With Fruits and Vegetables
The purpose of the research is to find out how well a new nutrition program works for elementary school students and their families. This program is called Brighter Bites.
- Trial name
- Brighter Bites (NCT02726529)
- Testing
- Brighter Bites, CATCH
- Where
- United States
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity, Childhood, Diabetes Mellitus, Type 2
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort
The QUebec Adipose and Lifestyle InvesTigation in Youth (QUALITY) Cohort study is a unique and comprehensive longitudinal study of 630 Caucasian children and their parents that was designed to investigate the natural history and…
- Conditions
- Obesity, Childhood, Diabetes Mellitus, Type 2, Cardiovascular Risk Factor, Pediatric ALL
- Trial name
- QUALITY (NCT03356262)
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Physical Inactivity, Obesity
Factors Associated With Physical Inactivity Among Adolescents
Despite the acknowledgment that physical activity is important for health, there are still few population-based or school-based studies that uses the current physical activity guidelines for adolescents.
- Conditions
- Physical Inactivity, Obesity, Overweight
- Trial name
- FAPIA (NCT01137227)
- Where
- Brazil
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Obesity
Anti-Obesity Phentermine-Topiramate Extended Release Pharmacotherapy vs Placebo Among Patients Using a Wearable Activity Tracker
Researchers are assessing the effects of weight loss medication vs a placebo among participants provided with a wearable activity tracker, digital wellness devices and lifestyle recommendations.
- Trial name
- NCT04408586
- Testing
- Phentermine-Topiramate Extended Release, Online support system
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight, Obesity
Effectiveness of PUSH Notifications From a Mobile App for Improving the Body Composition of Overweight or Obese Women
A clinical three-armed assay has been established to permit an evaluation of the effectiveness of implementing PUSH notifications in the actions orientated towards improving body composition through the establishment of dietary…
- Trial name
- NCT03911583
- Testing
- Control Group (CG), Moderate physical activity group (MPA), Intense physical activity group (IPA)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Córdoba
Obesity & Overweight
Precision Lifestyle Intervention and Anthropometric, Nutritional, and Metabolic Health Outcomes
This clinical trial aims to recruit a core cohort of adults with normal weight, overweight, and obesity, but without other metabolic alterations, to undergo a six-month nutritional intervention.
- Trial name
- MAR-GEN (NCT07450066)
- Testing
- Diet
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Obesity
Effect of Conjugated Linoleic Acid Supplement on Body Composition
The purpose of this clinical trial is to examine the effects of a low and high dose of conjugated linoleic acid supplement on body composition in obese humans.
- Trial name
- NCT00347373
- Testing
- Tonalin Conjugated linoleic acid (dietary supplement)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina
Obesity, Childhood
Improving Childhood Obesity-Related Behavior Change Through Better Risk Communication
One-third of American children are overweight or obese, leading to an increased risk for cardiovascular disease (CVD), early mortality, and other risks throughout their lifespan relative to normal weight children.
- Trial name
- NCT03074929
- Testing
- Novel risk communication
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Overweight, Obesity
Food, Adolescence, Mood, and Exercise
The overall objective of FAME is to examine the metabolic and behavioral links between dietary intake and its subsequent effects on circulating appetite regulating hormones and physical activity levels in Hispanic and African…
- Trial name
- FAME (NCT02015377)
- Testing
- High sugar versus low sugar meals
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity
The Impact of an Investment Based Intervention on Weight-loss and Beliefs About Food in Patients Post Bariatric Surgery
Although obesity surgery is currently the most effective method for achieving weight loss, not all patients lose the desired amount of weight and some show weight regain.
- Trial name
- NCT02045628
- Testing
- Investment intervention
- Where
- United Kingdom
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Obesity, Endocrine; Obesity
The Effect of Food Supplements on Food Intake and Gut Hormone Levels
When a meal is eaten, nutrients activate the release of hormones from the bowel into the blood stream. Normally there is a large amount of hormone released, which tells the brain that an individual is full and to stop eating.
- Conditions
- Obesity, Endocrine; Obesity, Appetite; Perverted
- Trial name
- NCT04292236
- Testing
- Lauric Acid, Perilla Oil and Diindolylmethane
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
PYY, Ghrelin
The Comparison of PYY, Ghrelin, GLP1, Glucose Level, Level of Satiety, and Ad Libitum Intake in Obese and Non-Obese Patients After Breakfast With Balanced Macronutrient Composition
Obesity can occur due to an imbalance of energy. This energy balance is greatly influenced by hunger and satiety. Obese person cannot resist hunger, while non obese can control hunger.
- Conditions
- PYY, Ghrelin, Appetite, Gut Hormones
- Trial name
- NCT03701503
- Testing
- Diet with balance composition to know the effect of a meal to gut hormones in obese and non obese women
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Breast Cancer Risk, Cardiovascular Disease Risk
The RISC Registry--Risk Informed Screening Registry
Chronic diseases such as heart disease, cancer, and diabetes are the leading causes of death and disability in the United States. Six in ten adults have one chronic disease; 4 in 10 have two or more.
- Conditions
- Breast Cancer Risk, Cardiovascular Disease Risk, Cardiometabolic Risk, Diabetes
- Trial name
- RISC (NCT05848856)
- Testing
- Breast Cancer, Cardiometabolic, Cardiovascular Risk Screening and Follow up
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Precision Health Equity Initiative
Overweight, Obesity
RCT to Compare Orlistat and Polyglucosamine for the Management of Overweight and Obesity
This trial compares two treatment methods: 1. Orlistat 60 mg to be taken three times daily one capsule; indicated for weight loss in overweight adults.
- Trial name
- NCT02529631
- Testing
- orlistat 60 mg, polyglucosamine
- Where
- 2 sites in Germany, Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Certmedica International GmbH
Obesity
Influence of Male Hormones on Regional Fat Metabolism
The male sex hormone, testosterone, plays an important role in determining body fat distribution in men. This is especially evident in the dramatic shift in body composition as boys and girls reach sexual maturity.
- Trial name
- NCT01160328
- Testing
- Leuprolide, Testosterone
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy, Vasodilation
Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation
The purpose of this project is to examine the impact of increases in brain insulin on sympathetic nervous system activity, as well as peripheral and cerebral blood flow in humans.
- Conditions
- Healthy, Vasodilation, Insulin Resistance, Autonomic Dysfunction
- Trial name
- NCT05153395
- Testing
- Carbon dioxide breathing, Neurovascular Coupling, Human insulin
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Overweight, Obesity
Influence of HDM1005 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin
The purpose of this study is to characterize the Influence of HDM1005 on gastric emptying and drug-drug interaction of HDM1005 and metformin, atorvastatin, warfarin, and digoxin in overweight/obese adult subjects.
- Trial name
- NCT07502001
- Testing
- Acetaminophen, Metformin, Warfarin
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Obesity, Diet, Food, and Nutrition
The Church as a Bridge to Deliver Health Resources Via Telehealth
The proposed Church Bridge intervention project will provide an innovative, evidence-based and technology supported, health intervention model for Southern, African American, and rural populations who continue to be disparately…
- Conditions
- Obesity, Diet, Food, and Nutrition, Church, Healthcare Disparities
- Trial name
- NCT02773069
- Testing
- Church Bridge Project
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Southern Mississippi
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