Clinical trials: Overweight
Obesity
Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Adolescent Bariatrics: Assessing Health Benefits and Risk
The five Teen-LABS clinical centers use standardized techniques to assess the short and longer-term safety and efficacy of bariatric surgery in adolescents compared to adults.
- Trial name
- Teen-LABS (NCT00474318)
- Where
- 3 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Overweight, Obesity
Family Lifestyle Overweight Prevention Program
The purpose of the study was to design a weight management program for Mexican American youth and to determine the effectiveness of the program for weight management compared to a self help program. 1.
- Trial name
- FLOW (NCT00454610)
- Testing
- FLOW, SelfHelp
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obesity, Insulin Resistance
Effects of Obesity and Intensity of Exercise on Ghrelin Levels
This study is investigating the effect of different intensities of exercise on levels of the hormone, ghrelin. In addition, we will be examining the relationship between any exercise induced changes in ghrelin and insulin…
- Conditions
- Obesity, Insulin Resistance, Cardiovascular Risk Factor
- Trial name
- NCT04581980
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Obese
Needle Radiofrequency Treatment for Submental Fat
The investigators aimed to evaluate the efficacy and safety of a fractional radiofrequency device with a micro-insulated needle to reduce submental fat.
- Trial name
- NCT05517824
- Testing
- microinsulated needle radiofrequency
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
160 Participants Aged 18-35 Years and Obese (BMI ≥30) Open to Men and Women of All Ethnicity
Glycemic Load & Resistance Training on Endothelial Function & Insulin Sensitivity
This project is prompted by the urgent public health need to identify novel strategies to prevent cardiovascular disease (CVD) and type 2 diabetes (T2D).
- Trial name
- GET FIT (NCT01755962)
- Testing
- Glycemic Load, Resistance Training
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gestational Weight Gain, Obesity
A Weight Maintenance Program Promoting Fat Loss in Pregnancy in Women With Obesity
The aims of this randomized controlled trial are to determine the effects of a lifestyle program that supports weight maintenance and fat mass loss during pregnancy in women with obesity on changes in 1) maternal weight, fat…
- Trial name
- Healthy Mamas (NCT04731688)
- Testing
- Weight Maintenance Group
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
Neuroendocrine Modulation of Metabolic Effects in Overweight Adolescents
This study will examine hormonal differences in ghrelin and growth hormone in obese and normal weight adolescents and their relationship to body composition and insulin resistance.
- Trial name
- NCT00140842
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Type 2 Diabetes, Obesity
Diabetes Virtual Trek: Obesity and Diabetes Prevention Through Science Enrichment
The purpose of this study was to evaluate the effectiveness of a school-to-home education program for it's ability to increase knowledge about, and ability to prevent type two diabetes in children and parents.
- Trial name
- DvtENERGY (NCT00542113)
- Testing
- DvtProgram ENERGY, DvtProgramENERGY
- Where
- 2 sites in United States
- Volunteers
- 1,703 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Obesity, Metabolic Disease
mTORC1 and Autophagy in Human Brown Adipocytes
The long term goal is to identify the potential therapeutic targets for the treatment of obesity and its associated disorders by studying the driving factors of activation of brown adipose tissue (BAT) in human adults.
- Trial name
- mTORHBFC (NCT04206124)
- Testing
- Brown Fat Harvest During Anterior Neck Surgery
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Overweight, Obesity
Evaluating the Impact of a Culinary Coaching Tele-medicine Program
Introduction: Obesity is a major public health problem and adopting healthy lifestyle habits, while effective, is challenging in real-world settings.
- Trial name
- NCT03823469
- Testing
- CCTP, Nutritional counseling
- Where
- 2 sites in United States, Israel
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Pediatric Obesity
Neural Mechanisms Underlying Children's Responses to Food Portion Size and Energy Density
Increased portion sizes of foods high in energy density (calories per gram of food) have been implicated in the obesity epidemic.
- Trial name
- NCT02759523
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Penn State University
Overweight and Obesity, Allergy
Effects of Vaginal Seeding on Infants' Body Mass Index and Allergy Risk for Caesarean-delivered Children
This is a single-blind randomized controlled trial, aiming to evaluate the effects of vaginal seeding on body mass index as well as allergy risk for cesarean-delivered infants.
- Trial name
- NCT03809390
- Testing
- Vaginal seeding
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Peking University
Obesity, Gastroesophageal Reflux
Ultrasound Assessment for Comparison of Gastric Residual Volume After Ingestion of Carbohydrate Drink and Water in Obesity Class II and III Volunteers at Risk of Aspiration
The goal of this clinical trial is to compare gastric residual volume between drinking a carbohydrate drink and water in obesity class II and III volunteers at risk of aspiration.
- Trial name
- CarbDrinkUltra (NCT06941623)
- Testing
- Ultrasonography of gastric residual volume, Point-of-care testing of glucose, Hunger numeric rating scale
- Where
- Thailand
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Diabetes Prevention, Obesity Prevention
Fluid Dairy Products Consumed Before and Within a Pizza Meal on Glycemic Response, Food Intake and Satiety in Children
The purpose of this study is to examine the effects of fluid dairy products on blood glucose and insulin, satiety and energy intake in normal weight and overweight/obese children in the age range of 9-14 y.
- Trial name
- NCT02147496
- Testing
- Dietary Intervention
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obstructive Sleep Apnea, Obesity
Lifestyle Modification Using an App in OSA
This study aimed to investigate the effects of a mobile phone app linked to hospital electronic medical record (EMR) system on weight reduction and obstructive sleep apnea (OSA).
- Trial name
- NCT03189940
- Testing
- Life style modification by using and app with a wrist-worn activity tracker, Conventional Life style modification
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Glucose Intolerance, Obesity
Physiological Effects of Stevia Consumption in Humans
This study will evaluate whether long-term consumption of the low calorie sweetener stevia affects glucose tolerance in healthy participants.
- Trial name
- NCT03993418
- Testing
- stevia
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Obesity
SMART: A Social and Mobile Weight Control Program for Young Adults
The Social/Mobile Approach to Reduce Weight (SMART) study is a 24-month randomized control trial designed to evaluate the hypothesis that weight status at 24 months will be significantly better for the SMART intervention…
- Trial name
- SMART (NCT01200459)
- Testing
- Social/mobile weight loss promotion intervention.
- Where
- United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity, Weight Loss
Lorcaserin in Obesity: Identification of CNS Targets Using fMRI
The purpose of this protocol is to investigate, using functional magnetic resonance imaging (fMRI), the effect of treatment with lorcaserin on centers of the brain that control appetite and food intake, as well as lorcaserin's…
- Trial name
- NCT02400359
- Testing
- Lorcaserin HCl
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Weight Loss, Mood
Effects of Lactobacillus Plantarum KABP-51 Probiotic on Body Composition, Microbiome and Mood in Healthy Overweight Adults
The objective of this study is to recruit 60 healthy moderately overweight subjects to participate in a research study investigating the effects of a specific probiotic strain (Lactobacillus plantarum KABP-51) on measures of…
- Trial name
- NCT06808061
- Testing
- Lactobacillus plantarum
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- 3 Waves Wellness
Body Weight
Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water
Sugar-sweetened beverages (SSBs) contribute an alarming ~7% of calories in the US diet among adults, making SSBs the single largest source of added sugar.
- Trial name
- SUB-POP (NCT04567108)
- Testing
- Maintain usual SSBs, Substitute to non-SSBs, Study app
- Where
- United States
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
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