Clinical trials: Overweight and Obese Women
Obesity
Increasing Physical Activity Among Overweight Women With Mobility Disabilities.
This study aims to increase physical activity among overweight African-American women with mobility limitations.
- Trial name
- PEP (NCT00164515)
- Testing
- Personalized exercise programme (PEP)
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Centers for Disease Control and Prevention
Metabolic Syndrome, Obesity & Overweight
Evaluating the SWW Method Dietary Intervention for HbA1c and Weight Management as a Preventative Intervention in Women
This study evaluated the SWW Method®, a 12-week dietary and lifestyle intervention based on the carbohydrate-insulin model, in a healthy cohort of women aged 35-75.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, Blood Glucose Monitoring, Type 2 Diabetes Prevention
- Trial name
- NCT07463417
- Testing
- SWW Method® Dietary and Lifestyle Intervention
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Sarah Wragge Wellness
WAGR Syndrome, Wilm's Tumor
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions
This study will explore conditions caused by the absence of certain genes on chromosome 11. These conditions include WAGR syndrome, which is characterized by a kidney tumor called Wilm s tumor, aniridia (absence of the iris of…
- Conditions
- WAGR Syndrome, Wilm's Tumor, Aniridia, Urogenital Abnormalities
- Trial name
- NCT00758108
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Metabolic Syndrome, Obesity
An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer
Among African-American women, in whom metabolic syndrome (MetS) is very prevalent and breast cancer mortality rates are high, it is hypothesized that intervening on MetS to improve the MetS profile may prove to be a means to…
- Trial name
- NCT02103140
- Testing
- Facility-based Exercise, Home-based Exercise
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Fractures, Bone, Bone Marrow Disease
Bone Marrow Adiposity and Fragility Fractures in Postmenopausal Women
The purpose is to determine in a case-control study if an association exist between bone marrow adiposity and fragility fractures in post-menopausal women.
- Conditions
- Fractures, Bone, Bone Marrow Disease, Fat Disorder, Adiposity
- Trial name
- ADIMOS (NCT03219125)
- Testing
- Dixon Magnetic Resonance Imaging, dual-energy X-ray absorptiometry (DXA)
- Where
- France
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Obesity, Insulin Resistance
Assessing the Value of Red Grapes Polyphenol Supplementation on Metabolic Parameters in Obese Insulinoresistant Subjects
Obesity, chronic disease, is a real public health problem because of its high prevalence but also because of the high risk of complications, including insulin resistance (IR) and type 2 diabetes (T2D).
- Conditions
- Obesity, Insulin Resistance, Menopause
- Trial name
- POLYGIR (NCT02633150)
- Testing
- Supplementation with red grapes polyphenol
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Obese Adolescents, Overweight
Effect of Acute Exercise on Biochemical Parameters in Normal-Weight and Overweight/Obese Adolescent.
The goal of this interventional clinical trial is to compare the acute physiological and biochemical responses to maximal physical exercise (Spartacus test).
- Trial name
- NCT07103889
- Testing
- Spartacus Test
- Where
- Tunisia
- Volunteers
- 35 people
- Sponsor
- High Institute of Sports and Physical Education of Kef
Obesity & Overweight, Gut Microbiota
Effects of Daily Kefir Consumption During Medical Nutrition Therapy on Body Composition and Psychological Well-Being in Women With Obesity
This randomized controlled study evaluated the effects of daily kefir consumption as an adjunct to medical nutrition therapy on body composition, biochemical parameters, gastrointestinal symptoms, bowel habits, and psychological…
- Conditions
- Obesity & Overweight, Gut Microbiota, Body Composition
- Trial name
- NCT07840274
- Testing
- Plain Kefir, Individualized Medical Nutrition Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Pınar Göbel
Insulin Resistance, Insulin Sensitivity
Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females
This is a feasibility study to examine the treatment with Metformin, vitamin D with calcium supplement for insulin resistance in obese, black, female teens.
- Conditions
- Insulin Resistance, Insulin Sensitivity, Obesity, Vitamin D Deficiency
- Trial name
- NCT01107808
- Testing
- Calcium and Vit D, Metformin, Vit D and Calcium
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cancer, Breast, Cancer, Uterus
With Love, Grandma ("Con Cariño, Abuelita") Pilot Study
The purpose of this study is to assess the feasibility, acceptability, and preliminary effects of a digital (web and mobile-phone-based) program to improve lifestyle behaviors (physical activity, dietary intake) among Hispanic…
- Conditions
- Cancer, Breast, Cancer, Uterus, Cancer, Ovary, Obesity
- Trial name
- NCT05721976
- Testing
- With Love, Grandma ("Con Cariño, Abuelita")
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Miami Sylvester Comprehensive Cancer Center
Risk Reduction, Urological Cancer
STRONG for Surgery & Strong for Life - Against All Odds: Intensive Prehabilitation for Risk Reduction in Cancer Surgery
Despite knowledge about the effect of preventive measures in lifestyle, smoking,nutrition, alcohol and physical activity (SNAP), there is a lack of systematic assessment of the overall lifestyle of the patient before surgery and…
- Conditions
- Risk Reduction, Urological Cancer, Surgery, Life Style
- Trial name
- STRONG-CS (NCT04088968)
- Testing
- Prehabilitation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Bispebjerg Hospital
Post-menopausal Women, Overweight and Obesity
Effect of (Poly)Phenolic on Cardiometabolic Risk of Postmenopausal Women
The purpose of this investigation is to test the hypothesis that in post-menopausal women with cardiometabolic risk, eating a relatively high daily amount of (poly)phenol-containing products (green tea, dark chocolate and…
- Trial name
- CARDIOGENE (NCT05255367)
- Testing
- (poly)phenols rich foods
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad de Murcia
Obesity, Cardiovascular Risk Factor
Hipoenergetic Effect of Diet Associated or Not With the Consumption of Coconut Flour in Women With Overweight
This study aimed to evaluate the effect of weight loss with diet combined coconut flour consumption improvement weight loss and reduction in glucose, cholesterol in obese women.
- Trial name
- NCT02152111
- Testing
- Coconut flour, Diet
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Body Weight, Appetitive Behavior
High Fat vs High Protein and Appetite Hormones
This study will investigate the effects of high-protein, high-fat snacks, specifically Greek yogurt, and peanuts, on satiety, gut hormones, and insulin secretion in overweight and obese women.
- Conditions
- Body Weight, Appetitive Behavior, Dietary Exposure, Hormone Deficiency
- Trial name
- NCT04518930
- Testing
- Peanuts or plain Greek yogurt
- Where
- Jordan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Al-Balqa Applied University
Endometrial Carcinoma, Obese
Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma
To investigate the efficacy of weight management plus megestrol acetate in obese patients with early endometrioid carcinoma（EEC）asking for fertility-sparing treatment
- Conditions
- Endometrial Carcinoma, Obese, Overweight, Fertility Issues
- Trial name
- NCT05316467
- Testing
- Intensive Lifestyle Intervention (ILI), Megestrol Acetate 160 MG Oral Tablet
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Xiaojun Chen
Breast Neoplasms, Obesity
Pilot Study of the Effect of Weight Loss on Breast Tissue and Blood Biomarkers in Women at Increased Risk for Breast Cancer
This is a pilot, non-randomized, single institution, observational study investigating the effect of dramatic weight loss secondary to bariatric surgery on biomarkers of breast cancer in tissue and blood as well as on imaging in…
- Trial name
- NCT02681120
- Testing
- Biopsy, Blood draw, Mammogram
- Where
- 3 sites in United States
- Volunteers
- 3 people
- Sponsor
- Tarah J Ballinger, MD
Obesity, Metabolic Syndrome
Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With or Without Metabolic Syndrome Risk Factors - A Study Protocol for a Double-blind, Randomised, Multi-center, Placebo-controlled Clinical Trial
The Purpose of this trial is to investigate the efficacy and safety of GGT on Korean obese Women with or without metabolic syndrome Risk factors
- Trial name
- NCT03479346
- Testing
- GGT
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Gachon University Gil Oriental Medical Hospital
Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma
A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer
This phase II trial studies whether adding tirzepatide injections to a levonorgestrel intrauterine device (LNG-IUD) improves pathologic response (absence of cancer cells in tissue samples after treatment) in women with…
- Trial name
- NCT07349641
- Testing
- Medical Device Usage and Evaluation, Tirzepatide
- Where
- 3 sites in United States
- Volunteers
- 55 people
- Sponsor
- National Cancer Institute (NCI)
Obesity
Pilates Exercises Versus Intermittent Fasting Diet on Physical and Metabolic Aging Process in Obese Perimenopausal Women
This study aims to compare the effect of pilates exercises versus intermittent fasting diet on physical and metabolic aging parameters in obese perimenopausal women.
- Trial name
- NCT07683286
- Testing
- Pilates exercise, Intermittent Fasting Diet
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Obesity, Physical Activity
Coalition for a Healthier Community-Utah Women and Girls - Phase II (UWAG-II)
This 12-month randomized trial is designed to evaluate the impact of low intensity (quarterly) versus high intensity (monthly) wellness coaching programs on women's success achieving individual health goals related to active…
- Conditions
- Obesity, Physical Activity, Diabetes
- Trial name
- UWAG-II (NCT02470156)
- Testing
- High Intensity Arm (Intervention), Low Intensity Arm (Comparison)
- Where
- United States
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- University of Utah
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