Clinical trials: Oximetry
Coronavirus, Cardiac Disease
Can Remote Photoplethysmography Be Used for Contactless Vital Sign Acquisition in a Healthcare Setting? A Prospective Comparative Study.
Contactless and widely available health monitoring technologies are of growing interest in the context of the worldwide COVID-19 pandemic.
- Conditions
- Coronavirus, Cardiac Disease, Respiratory Disease, Vascular Diseases
- Trial name
- NCT04489407
- Testing
- Remote Photoplethysmography (rPPG) vital sign acquisition
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Lady Davis Institute
Cardiac Surgery, Shock
Hemoglobin Saturation in Superior Vena Cava and Right Atrium
The aim of the study is to compare oxygen saturation of blood samples collected from the superior vena cava, the right atrium, and the pulmonary artery.
- Trial name
- NCT01398436
- Testing
- central venous catheter positioning in right atrium
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Catholic University of the Sacred Heart
Postoperative Delirium in Elder Patients After Spine Surgery
Predictors of Postoperative Delirium in Elder Patients After Spine Surgery: Regional Cerebral Oxygen Saturation
Postoperative delirium is an important problem in patients undergoing major surgery. The incidence of delirium was 12.5% in the patients over 70 years old undergoing spine surgery.
- Trial name
- NCT02331953
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Yonsei University
Microcirculation, Photoplethysmography
Evaluation of Microcirculation With Photoplethysmography (Pulse Oximetry) in Healthy Volunteers and Ventilated Patients
The objective of this observational study is to explore microcirculation in healthy volunteers and in ventilated patients in the operating room and in critical care.
- Trial name
- NCT06141681
- Testing
- photoplethysmography
- Where
- Argentina
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Obstructive Sleep Apnea
Oxygen Saturation Patterns in Post-Op Patients at Risk for Obstructive Sleep Apnea
This study will include patients who have major surgery and are at risk for or have been diagnosed with sleep apnea. The patients will be monitored the night after surgery for repeating episodes of reduced breathing and oxygen…
- Trial name
- NCT01078207
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Tracheo Esophageal Fistula, Congenital Diaphragmatic Hernia
Cerebral Blood Flow in Neonates During Thoracoscopic Surgeries
the aim of this study is to compare the effect of different modes of mechanical ventilation by using volume-controlled ventilation and pressure-controlled ventilation on cerebral blood flow monitored by cerebral oximetry during…
- Trial name
- NCT04507295
- Testing
- cerebral oximetry ( INVOS 5100 )
- Volunteers
- 30 people
- Sponsor
- Cairo University
Surgery
Calibration and Validation of Masimo's O3 Regional Oximetry Device in Neonates, Infants and Children
The study will collect cerebral oximetry data from pediatric and neonatal subjects using the Masimo O3 regional oximetry device, for the purposes of device calibration and validation.
- Trial name
- NCT03123354
- Testing
- O3 regional oximeter sensor
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Masimo Corporation
Healthy Subjects
Safety and Efficacy of Trans Sodium Crocetinate (TSC) in Enhancing Tissue Oxygen Levels in Healthy Volunteers
Randomized, double-blind, placebo-controlled, pharmacokinetic, pharmacodynamic study. Subjects will be randomized to TSC or placebo to determine the effect of Trans Sodium Crocetinate (TSC) on Transcutaneous Oximetry Measurements…
- Trial name
- NCT04808622
- Testing
- Trans-Sodium Crocetinate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Diffusion Pharmaceuticals Inc
Unstable Blood Pressure, Hypotension
Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS
The goal of this study is to evaluate if a novel near-infrared spectroscopy (NIRS) device can accurately estimate blood pressure in newborns at risk for unstable blood pressure.
- Trial name
- NCT06994494
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Carotid Stenosis
Perioperative GFAP and Neurological Complications After Carotid Endarterectomy
This prospective, single-center observational study will evaluate whether blood levels of glial fibrillary acidic protein (GFAP), a protein associated with injury to supporting cells in the brain, are related to neurological…
- Trial name
- NCT07843979
- Testing
- Serum GFAP Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Filiz Ata
Pulse Oximetry
Pulse Oximetry and Skin Pigmentation - Peds
The investigators' study aims to study how melanin index (mx) affects the deviation between SpO2 and SaO2, which becomes generally greater as hypoxia increases.
- Trial name
- NCT05185427
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Minnesota
Lung Diseases
Pulse Oximetry With Clinical Observation to Screen for Lung Disease in Neonates
The investigator assessed the feasibility and reliability of pulse oximetry plus clinical observation for detection the lung disease in neonates.
- Trial name
- NCT02533583
- Testing
- pulse oximetry (PHILIPS intelliven MP5)
- Volunteers
- 15,000 people
- Sponsor
- Guangdong Women and Children Hospital
Parkinson Disease
Retinal Biomarkers in Parkinson´s Disease
The goal of this observational study is to determine whether oxygen content of the retinal vessels of the eye may serve as a biomarker in Parkinson´s disease. The main questions it aims to answer are: 1.
- Trial name
- NCT06929026
- Where
- Iceland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Newborn, Birth, Preterm
Pulse Oximetry Performance Comparison in Newborns
The overall purpose is to directly compare pulse rate (PR) acquisition and oxygen saturation performance between two pulse oximeters (PO) in newborns.
- Trial name
- NCT06637917
- Testing
- OxySoftN™ Neonatal-Adult SpO2 Sensor with N600X Nellcor™ Patient Monitoring System, LNCS® NEO SpO2 Sensor with RAD-97™ Pulse CO-Oximeter, 1041PTS (or similar) Kendall™ Neonatal Electrodes with IntelliVue MP5 Portable Patient Monitor
- Where
- 3 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Oxygen Saturation
Diagnostic Study of Huami Smart Wearable Device
This is a cross-sectional diagnostic study. In this study, wrist oxygen saturation (SwO2) will be measured by Huami smart wearable device, SpO2 of pulse oxygen saturation monitor with medical device registration certificate and…
- Trial name
- DSHWD (NCT04429906)
- Testing
- Huami smart wearable device
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Heart Failure
The Effects of a High Fat and Low Carbohydrate Diet on Clinical Status in Patients With Heart Failure
The aim of the present study was to evaluate the effects of a high fat, low carbohydrate (CHO) diet on clinical status during 60 days of follow-up in patients with stable heart failure (HF).
- Trial name
- NCT02150798
- Testing
- High fat and low carbohydrate diet, Control diet
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Stroke, Ischemic, Stenosis, Carotid
Impact of Significant Carotid Stenosis on Retinal Perfusion Measured Via Automated Retinal Oximetry
Background: Large vessel carotid stenosis represent significant cause of ischaemic stroke. Indication for surgical revascularisation treatment relies on severity stenosis and clinical symptoms.
- Trial name
- NCT06085612
- Testing
- Automated retinal oximetry
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- University Hospital Olomouc
Perfusion Index
Comparison of Perfusion Index Monitoring Using a Smartwatch and a Pulse Oximeter
The aim of the study is to experimentally compare measured perfusion index values between smartwatch and a medical grade pulse oximeter in healthy subjects at rest and with and without motion artifacts and during exercise.
- Trial name
- PIWATCH (NCT06626217)
- Testing
- Resting conditions, Movement artifacts, Circulation constriction
- Volunteers
- 50 people
- Sponsor
- Czech Technical University in Prague
Acute Kidney Injury
Renal Oximetry-Guided Anesthesia With Near-Infrared Spectroscopy for Improved Postoperative Outcomes
The trial is a prospective, randomized, single-blind, pilot study investigating whether near-infrared spectroscopy (NIRS)-guided optimization of intraoperative renal oxygen saturation reduces postoperative acute kidney injury…
- Trial name
- ROGAR (NCT07141693)
- Testing
- NIRS-guided management, Standard anesthesia management
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Hypoxia
Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery
This is a prospective, randomized controlled pilot study of cerebral oximetry use in elderly patients undergoing thoracic surgical procedures that require the use of single lung ventilation.
- Trial name
- NCT01866657
- Testing
- Vasoconstrictor Agents, Head/neck repositioning, Increase ETCO2
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University Hospitals Cleveland Medical Center