Clinical trials: Oxygen Delivery
Blood Viscosity
The Effect of Succinylated Gelatin on the Blood Viscosity and Oxygen Delivery
The study is to investigate the effect of succinylated gelatin on the blood viscosity and oxygen delivery in patients during surgeries, so as to have a better understanding of the safety in the use of succinylated gelatin for…
- Trial name
- NCT02631356
- Testing
- Ringer's lactate solution, Succinylated gelatin
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Healthy Adult, Fitness Testing
Molecular Indicators of Systematic Fitness
The goal of this study is to characterize associations between cardiorespiratory fitness, as measured by VO₂max/VO₂peak, and blood-based molecular measurements in adults.
- Conditions
- Healthy Adult, Fitness Testing, Athlete, Aging
- Trial name
- MISFIT (NCT07393841)
- Testing
- There is no intervention.
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- VO Health, Inc.
Deep Sedation
Comparison of Oxygenation Methods in Sedation
Abstract Backgrounds and objectives: Dental treatments, especially in children who can not be cooperated, may require deep sedation due to intense anxiety and fear.
- Trial name
- NCT03893877
- Testing
- nasal cannula, nasal mask
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Sudden Unexplained Infant Death, Apnea of Newborn
Advanced Wireless Sensors for Neonatal Care in the Delivery Room
The goals of this observational study is to assess whether a new advanced wireless skin sensor vital sign monitoring system can effectively monitor the vital signs of healthy newborn infants (≥ 35 weeks gestational age).
- Conditions
- Sudden Unexplained Infant Death, Apnea of Newborn, Newborn Morbidity, Newborn Asphyxia
- Trial name
- AWARD (NCT06693817)
- Testing
- Wireless skin sensors vital sign monitoring system, Wired vital sign monitoring system
- Where
- 5 sites in Brazil, Canada and 2 more
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Guilherme Sant'Anna, MD
Cesarean Delivery Affecting Newborn
Preoperative Highflow Nasal Oxygen Application in Cesarean Under General Anesthesia and Its Effects on Newborn.
Preoperative Highflow Nasal Oxygen Application in Cesarean Under General Anesthesia and Its Effects on Newborn.
- Trial name
- NCT03903003
- Testing
- high flow nasal oxygen device (POİNT), Face mask
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Oxidative Stress, Fetal Distress
Maternal Oxygen Use During Delivery and Cord Blood Superoxide Dismutase
When exposed to oxygen immediately after birth, newborns suffer from an oxidative stress with a significant decrease in serum concentration of the anti-oxidant enzyme superoxide dismutase.
- Trial name
- NCT01042262
- Testing
- Oxygen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- George Washington University
Prematurity
Oxygen Saturation and Caffeine Post-Discharge
This study aims to determine normative values of oxygen saturation in late preterm infants, and evaluate the frequency of hypoxic events in infants requiring caffeine at discharge and those not requiring it.
- Trial name
- OCPDPS (NCT02386046)
- Testing
- Pulse oxymeter measurements
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Oxygen Delivery Systems at Altitude
Aviation Portable Oxygen Delivery System
This study aims to investigate dose based oxygen delivery vs. continuous flow of oxygen during simulated altitude conditions as would be experienced after a loss of pressure during commercial aircraft flight.
- Trial name
- NCT03425409
- Testing
- Integra Pulse Portable- Continuous flow, Integra Pulse Portable- Pneumatic pulsed flow
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Bronchopulmonary Dysplasia, Very Low Birth Weight Infant
Work of Breathing in Premature Infants at Discharge
The purpose of this study is to compare how premature infants who required oxygen for at least 28 days during their time in the NICU (Neonatal Intensive Care Unit) breathe at discharge compared to premature infants who did not…
- Conditions
- Bronchopulmonary Dysplasia, Very Low Birth Weight Infant, Prematurity
- Trial name
- NCT03682575
- Testing
- Enrollment
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Type 2 Diabetes
Type 2 Diabetes and Exercise Function in Single Leg Exercises
This study plans to learn more about the effects of type 2 diabetes (T2DM) on exercise blood flow and muscle oxygen uptake. This study will evaluate \& compare exercise function during single leg plantar flexion exercise in a…
- Trial name
- NCT01793909
- Testing
- Single Leg Exercise Training
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Impaired Oxygen Delivery, Critically Ill Patient
Non-Invasive Measurement of SjvO2 Using Near Infrared Spectroscopy in Critically Ill Patients
ScvO2 is an important parameter in the management of critically ill patient. The only way to measure it is to have an internal jugular or subclavian central venous catheter.
- Trial name
- NIRS-SCJVO2 (NCT04624009)
- Where
- 2 sites in Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Oxygen Delivery, Patient Monitoring
Evaluation of Oxygen Delivery Through Nasal Cannula in Volunteers
This study will evaluate patient comfort and oxygen delivery efficiency when providing supplemental oxygen through a nasal cannula to volunteers using an instrumented oxygen delivery system.
- Conditions
- Oxygen Delivery, Patient Monitoring, Patient Comfort
- Trial name
- NCT02886312
- Testing
- Supplemental Oxygen Delivery System
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester
Tidal Neonatal NO, Vitamins A and D, and Infant Lung Disease - The AD-ON Study
Children born prematurely are of greater risk of developing chronic lung disease (Bronchopulmonary Dysplasia). With an increase in the amount of premature children, we expect an increasing number of children with BPD.
- Conditions
- Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester, Bronchopulmonary Dysplasia
- Trial name
- NCT01722760
- Testing
- measurements
- Where
- 2 sites in Denmark
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Neonatal Disorder
Effects of Mother Position in Skin-to-skin Contact Newborn on Oxygen Saturation Levels.
The purpose of this study is to determine if the position of the mother in the first two hours after delivery, while she is in skin to skin contact with your child, influences the oxygen saturation and/or heart rate of the…
- Trial name
- NCT02585492
- Testing
- Head-of-bed elevated 15°, Head-of-bed elevated 45°
- Where
- 7 sites in Spain
- Volunteers
- 1,243 people, healthy volunteers welcome
- Sponsor
- Red Salud Materno Infantil y del Desarrollo
Healthy
Effects of Kilohertz-frequency and Low-frequency Current on Triceps Surae
Neuromuscular electrical Stimulation (NMES) can minimize muscle atrophy and complications related to muscle disuse and help improve neuromuscular performance.
- Trial name
- NCT05894044
- Testing
- Russian current 10%, Aussie current 10%, Pulsed current 500 µs phase
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Kangaroo-mother Care
Skin-to-skin Contact Between Premature Infant and Mother
Aim: To determine the effect of kangaroo mother care (KMC) on perfusion index, heart rate, and oxygen saturation in premature infants who were discharged early and admitted to the neonatal intensive care in the following days.
- Trial name
- NCT06380231
- Testing
- kangaroo mother care (KMC)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Istanbul Rumeli University
Acute Myocardial Infarction, STEMI
Delivery SSO2 Therapy for 60 Min in Anterior MI Patients With PCI ≤ 6 Hours of Symptoms Onset Compared to Standard.
A multi-center randomized post-approval evaluation of delivery of intracoronary hyperoxemic supersaturated Oxygen therapy for 60 minutes in anterior AMI patients with successful reperfusion (via PCI) within 6 hours after onset of…
- Trial name
- NCT04743245
- Testing
- TherOx DownStream System, PCI
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- TherOx
Bleeding as Surgical Complication (Treatment)
HemOx Transfusion Trial
The proposed project, entitled "HemOx Transfusion Study", investigates the functionality of red blood cells (erythrocytes) in the context of oxygen transport in the blood.
- Trial name
- NCT07677150
- Testing
- autologous maschine transfusion - intraoperative cell salvage, packed red blood cells
- Where
- Austria
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
CHD - Coronary Heart Disease
Influence of Anesthetics on Clinical Outcome During Cardiac Surgery in Adults
Abstract Cardiac surgery in adults is associated with the occurrence of post-operative complications. Even minor complications can increase the cost of their treatment.
- Trial name
- NCT05693428
- Testing
- Propofol, Isoflurane, Sevoflurane
- Where
- Kazakhstan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Astana Medical University
Obstructive Apnea
Comparison of a Demand Oxygen Delivery
Conducting a randomized control trial of oxygen in children with Down syndrome to treat moderate to severe obstructive sleep apnea.
- Trial name
- DOSA (NCT06609694)
- Testing
- Portable oxygen concentrator Inogen G5 model
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati