Clinical trials: Oxygen Disorders
Pneumonia, Interstitial, Cancer Patients
Study of of Oxygen Nebulized Inhalation EGCG in Cancer Patients With New Coronary Pneumonia
Epigallocatechin-3-gallate (EGCG) is a major polyphenol of green tea that possesses a wide variety of actions, such as anti-inflammatory, anti-fibrotic, pro-apoptotic, anti-tumorous, and metabolic effects via modulation of a…
- Trial name
- NCT06924749
- Testing
- EGCG
- Where
- 2 sites in China
- Volunteers
- 111 people
- Sponsor
- Shandong Cancer Hospital and Institute
Lung Collapse
HFNC for Induction During Bariatric Surgery Patients.
This study aims to compared the effects of high flow nasal during the induction and during the weaning of anesthesia on intraoperative and postoperative oxygenation and postoperative atelectasis in obese patients undergoing…
- Trial name
- NCT03155711
- Testing
- HFNC group, Standard group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder
HBOT Effects on First Responders' Cognition and Well-Being
The goal of this study is to examine changes in cognitive functioning and post-concussive symptoms following hyperbaric oxygen therapy (HBOT) in current and former first responders with a history of traumatic brain injury.
- Conditions
- Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT07852728
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Summit Hyperbarics and Wellness
Acute Coronary Syndrome
Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.
In the management of acute coronary syndromes with ST-segment elevation (STEMI), early analgesia reduces the effects of hyperadrenalism which increases the size of myocardial infarction.
- Trial name
- SCADOLII (NCT02198378)
- Testing
- MEOPA and paracetamol, Morphine
- Where
- 40 sites in France, Reunion
- Volunteers
- 680 people
- Sponsor
- University Hospital, Toulouse
Brain Injury, Myocardial Injury
Preconditioning With Hyperbaric Oxygen in Cardiovascular Surgery
Animal studies have shown that preconditioning with hyperbaric oxygen can induce central nervous system and heart ischemic tolerance.
- Trial name
- NCT00817791
- Testing
- Hyperbaric oxygen pretreatment (GR2200)
- Volunteers
- 49 people
- Sponsor
- Xijing Hospital
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Lumbar Radiculopathy, Lumbar Disc Herniation
Randomized Evaluation of Lumbar Injection Effectiveness and Function
The goal of this clinical trial is to learn whether the Triojection® System is safe and effective for treating symptomatic lumbar radiculopathy (leg pain caused by nerve irritation or compression) resulting from a contained…
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Contained Herniated Lumbar Disc
- Trial name
- RELIEF (NCT07856810)
- Testing
- Triojection® System, Selective Nerve Root Block (SNRB)
- Volunteers
- 300 people
- Sponsor
- SpinaFX Medical Inc.
Neonatal Disease, Altitude Hypoxia
Reference Interval for SPO2 in Neonates at High Altitudes During First 2 Hours and Umbilical Artery Blood Gas
Pulse oximetry offers real time and non-invasive estimation of arterial oxygen saturation in a cost-effective way, and has become a critical tool in guiding the usage of supplemental oxygen in sick newborns.
- Trial name
- NCT05468515
- Testing
- pulse oxygen saturation
- Where
- China
- Volunteers
- 956 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Congenital Heart Disease, Infant, Premature, Diseases
The Research of the Effect of Sevoflurane on Brain-protection of Cardiac Surgery in Infants.
To observe the effect of sevoflurane on the concentration of S100β and regional cerebral oxygen saturation in infants with congenital heart disease undergoing cardiac surgery.
- Trial name
- NCT03366597
- Testing
- Sevoflurane
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jun Ma
Heart Defects, Congenital
Mixed Venous Oxygen Saturation From Central Venous Line, Venous Side of Heart Lung Machine and the Pulmonary Artery
This study was designed to examine if venous saturations from the central venous line and from the venous side of the heart lung machine are interchangeable or not with mixed venous saturation from the pulmonary artery in…
- Trial name
- NCT02498626
- Testing
- venous saturations
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Retinitis Pigmentosa
Slowing the Degenerative Process, Long Lasting Effect of Hyperbaric Oxygen Therapy in Retinitis Pigmentosa
Our aim was to assess the role and usefulness of Hyperbaric oxygen therapy in a long lasting period, assessing its efficacy on rescuing retinal photoreceptors and preserving visual function in retinitis pigmentosa.
- Trial name
- NCT00461435
- Testing
- hyperbaric oxygen therapy
- Where
- Italy
- Sponsor
- Azienda Policlinico Umberto I
Interstitial Cystitis
Prospective Trial Comparing Response to Hyperbaric Oxygen Treatment in Patients With Interstitial Cystitis
To review the results of Hyperbaric Oxygen therapy (HBOT) on the symptoms of interstitial cystitis (IC). To determine if there is greater symptom improvement in the ulcerative vs the non-ulcerative patients with interstitial…
- Trial name
- NCT01479725
- Testing
- HBOT
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Kenneth Peters, MD
Branch Retinal Artery Occlusion, Central Retinal Artery Occlusion
Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye
Canadians fear loss of vision more than any other disability. Vision loss has an enormous impact on quality-of-life and is extremely costly from a societal and economic perspective.
- Conditions
- Branch Retinal Artery Occlusion, Central Retinal Artery Occlusion, Branch Retinal Vein Occlusion, Central Retinal Vein Occlusion
- Trial name
- NCT01348633
- Where
- Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Systemic Oxygenation vs ROS Formation in TBI Patients
ROS in TBI Patients in Relation to Level of Oxygenation.
This project an observational study performed on patients with severe Traumatic Brain Injury (TBI) treated at Neurosurgical ICU (NICU) at Karolinska University Hospital.
- Trial name
- ROS-TBI (NCT05101278)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Stockholm
Type 2 Diabetes Mellitus
The Acute Effect of Interval-walking
Four months of interval walking training (IWT) is superior to energy-expenditure matched continuous walking training (CWT) with regards to weight loss and improvements in glycemic control. The reason for this is unclear.
- Trial name
- acute IWS (NCT01987258)
- Testing
- Interval Walking, Continuous walking
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pulmonary Fibrosis, Pulmonary Hypertension
A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis
A randomized, double-blind, placebo-controlled dose escalation study to assess the safety and efficacy of pulsed, inhaled nitric oxide (iNO) in subjects with pulmonary fibrosis on long term oxygen therapy.
- Trial name
- NCT05747508
- Testing
- INOpulse®, Long Term Follow Up
- Where
- 23 sites in United States
- Volunteers
- 85 people
- Sponsor
- Bellerophon
Metabolic Dysfunction-associated Steatotic Liver Disease, Hepatic Steatosis
Hyperbaric Oxygen Therapy for Metabolic Dysfunction-associated Steatotic Liver Diseases
The goal of this clinical trial is to learn if hyperbaric oxygen therapy (HBOT) works to treat Metabolic Dysfunction-associated Steatotic Liver Diseases (MASLD).
- Conditions
- Metabolic Dysfunction-associated Steatotic Liver Disease, Hepatic Steatosis, Non-alcoholic Fatty Liver Diseases
- Trial name
- MASLD (NCT06619808)
- Testing
- Hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Jinling Hospital, China
COPD(Chronic Obstructive Pulmonary Disease)
Evaluation of Reactive Oxygen Metabolites in the Value of COPD
This study through the long-term observation followed up for 2 years to find the change of the COPD patients blood ROMs, systematically evaluate the relationship between ROMs and the severity of COPD.
- Trial name
- NCT02297633
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Heart Failure With Preserved Ejection Fraction, Atrial Fibrillation
Exercise Capacity Before and After AF Ablation in Patients With HFpEF
In a prospective, observational pilot study of patients scheduled for an atrial fibrillation (AF) ablation at the University of Vermont Medical Center the investigators will compare exercise capacity before and four months after…
- Trial name
- NCT05376748
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Vermont
Cardiac Arrest, Hypoxia
Effectiveness of Chest Compressions Under Mild Hypoxia
The purpose of this study is to evaluate the effect of breathing a slightly reduced amount of oxygen will have on a rescuer's ability to provide chest compressions during CPR.
- Trial name
- NCT04072484
- Testing
- Mild hypoxia
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Chicago
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