Clinical trials: Oxygen Kinetics
Cardiovascular Diseases, Coronary Artery Disease
The Effect Of An Expanded Long Term Periodization Exercise Training In Patients With Cardiovascular Disease
Benefits from cardiac rehabilitation (CR) programs are evidence based and widely recognized. Less than 50% of people who participate in hospital-based CR programs maintain an exercise regimen for as long as six months after…
- Trial name
- NCT03335319
- Testing
- Periodized Exercise Training Regime, Non Periodized Exercise Training Regime
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- University of Lisbon
Cardiopulmonary Exercise Test, Hypertrophic Cardiomyopathy
Exercise Oxygen Kinetic and Cardiac Output in Hypertrophic Cardiomyopathy
Fatigue and dyspnea that reduce exercise performance are common symptoms in patients with hypertrophic cardiomyopathy. Since the cause of this functional limitation has not yet been described, this study aims to evaluate the…
- Conditions
- Cardiopulmonary Exercise Test, Hypertrophic Cardiomyopathy, Cardiac Output Measurement
- Trial name
- NCT05754489
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Centro Cardiologico Monzino
Type 1 Diabetes Mellitus
Priming Exercise in Type 1 Diabetes
Critical power is an important threshold in exercise physiology, and is an important determinant of the ability to tolerate high-intensity exercise.
- Trial name
- PET1D (NCT03285386)
- Testing
- Priming exercise, Control Exercise
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Liverpool Hope University
Heart Failure, Chagas Disease
Effect of Ganglionar Electrical Stimulation on Central Arterial Pressure
This study will evaluate the applications of ganglionar electrical stimulation in patients with Chagas Disease and Ischemic Heart Failure patients.
- Trial name
- NCT01874795
- Testing
- TENS
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Oxygen Utilization, Oxygen Kinetics
Mushroom Blend on Oxygen Kinetics
Purpose: To determine the acute effects of a mushroom blend vs. placebo on oxygen kinetics, aerobic power and time to fatigue in healthy adults.
- Trial name
- NCT02075892
- Testing
- Mushroom Blend
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cardiovascular Disease
Fitness and Daily Function in Adults
The purpose of this study is to examine the impact of aerobic fitness on the ability of able and disabled older adults to perform daily functional activities.
- Trial name
- NCT00018265
- Testing
- Task specific endurance training, Tai Chi
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Chronic Obstructive Pulmonary Disease
Bronchodilators and Oxygen Kinetics With Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients
Hypothesis: The reduction of dynamic hyperinflation and its negative effects on the respiratory system following a bronchodilator could lead to an improvement of cardiac function in terms of increased cardiac output.
- Trial name
- NCT00354354
- Testing
- Combivent
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Queen's University
Chronic Obstructive Pulmonary Disease, Healthy
Effect of Two Physical Training Programs on Oxygen Uptake and Heart Rate On-kinetics in Patients COPD
Patients with chronic obstructive pulmonary disease (COPD) present slowed pulmonary oxygen uptake (VO2) and heart rate (HR) kinetics compared with age-matched controls.
- Trial name
- BVPS-123 (NCT01529489)
- Testing
- Resisted/Aerobic physical training, Interval physical training in elliptical equipament
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Anesthetized Healthy Patients (ASA 1 or 2) in the Supine Position, Excluding Head, Neck and Head Surgeries, Anesthetized Patient With Severe Systemic Disease (ASA 3 or 4)
Gas Kinetics and Metabolism in Anesthesia During Non Steady State
During clinical anesthesia, it is astonishing that CO2 monitoring consists mainly of end-tidal PCO2 to confirm endotracheal intubation and to estimate ventilation, and O2 monitoring consists of a single PO2 measurement to detect…
- Trial name
- NCT00225381
- Testing
- connection of measuring device to anesthesia circuit, drawing of blood sample through an arterial line, placed according to clinical criteria by primary anesthesia team, changing operating room bed position (head down and up position)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Non Small Cell Lung Cancer
Evaluation of NSCLC Patients' Oxygen Uptake On-kinetics at Cycle-ergometer During Prehabilitation
In developed countries cancer has become the second leading cause of death after cardiovascular disease. The lung is a particularly exposed organ since broncho-pulmonary cancers rank second in terms of incidence, and the first…
- Trial name
- Preo-Kinetics (NCT04041297)
- Testing
- Preoperative Pulmonary Rehabilitation
- Where
- France
- Volunteers
- 34 people
- Sponsor
- ADIR Association
Pulmonary Disease, Chronic Obstructive
The Effect of Respiratory Training on Exercise Tolerance in COPD
Exercise intolerance is one of the key disabling factors in patients with chronic obstructive pulmonary disease (COPD). Although multifactorial, exercise intolerance involves physiological interactions between respiratory and…
- Trial name
- ERTET (NCT04201522)
- Testing
- Normocapnic hyperpnoea intervention
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Allogeneic Hematopoietic Stem Cell Transplantation (HSCT), Oxygen Deficiency
Impact of Closed PBSC Collection With Reduced Gas-Phase Oxygen Exposure on Graft Quality and Early Engraftment in Allo-HSCT
This study aims to establish a closed PBSC collection procedure with reduced gas-phase oxygen exposure and to verify its impact on graft functional quality and clinical engraftment efficiency.
- Conditions
- Allogeneic Hematopoietic Stem Cell Transplantation (HSCT), Oxygen Deficiency, Graft Function
- Trial name
- NCT07904234
- Testing
- Closed PBSC collection with reduced gas-phase oxygen exposure
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Aging, Sedentary Behavior
Impact of Cocoa Flavanols on Pulmonary Oxygen Uptake Kinetics and Exercise Tolerance in Sedentary Middle-aged Adults
In recent years, there has been significant interest in dietary flavonoids (biologically active plant-derived compounds) as potential therapeutics.
- Trial name
- NCT04370353
- Testing
- Cocoa flavanols
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Normobaric Hypoxia, Hypoventilation
"Living Low - Training High" Methods and Physiological Responses in Well-trained Swimmers
To overcome the lack of knowledge regarding the impact of different "living low, training high" methods on swimming performance, a 4-week intervention will be carried out to determine and compare the effects of three Repeated…
- Conditions
- Normobaric Hypoxia, Hypoventilation, Normoxia
- Trial name
- NCT06253039
- Testing
- Repeated sprint
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Healthy
Oxygen Uptake Kinetics During Recovery From Maximal and Submaximal Exercise
Measurements of dynamic changes in oxygen uptake (VO2 kinetics) during recovery from exercise may describe regulatory control of oxygen transport and utilization and have greater reliability and less inherent risk than assessment…
- Trial name
- NCT00001519
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Down Syndrome
Oxygen Uptake Kinetics During Submaximal Exercise in Adults With Down Syndrome
This study aims to compare the rate at which oxygen uptake adapts to submaximal, moderate intensity exercise (oxygen uptake kinetics) between adults with and without Down syndrome, to determine the contribution of oxygen uptake…
- Trial name
- NCT05995223
- Testing
- Submaximal exercise protocol
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Type 2 Diabetes Mellitus, Diabetic Kidney Disease
Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study.
Current study will render insight in to the role of renal hypoxia in the diabetic kidney and is able to associate its finding with measurements of renal perfusion and glomerular filtration rate.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Kidney Disease, Diabetic Nephropathy, Renal Hypoxia
- Trial name
- ROCKIES (NCT04027530)
- Testing
- Ertugliflozin 15 mg
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Carbon Monoxide Poisoning
Carbon Monoxide Monitoring and Emergency Treatment
Carbon monoxide (CO) has been called a "silent killer", and those patients who survive CO poisoning are at risk of neurological damage, which may be permanent.
- Trial name
- COMET (NCT00841165)
- Testing
- Continuous Positive Airway Pressure, Non-rebreather oxygen mask
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Vermont