Clinical trials: Oxygen Utilization
Cystic Fibrosis
Interactive Video Game Responses in Cystic Fibrosis
Cystic fibrosis (CF) is a disease that affects multiple systems, however, the accumulation of secretion in the airways contributes to the fact that pulmonary complications are the main responsible for the high rates of morbidity…
- Trial name
- Igamecf (NCT03229213)
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Covid19
Use of Hyperbaric Oxygen Therapy to Treat COVID-19 Patients With Respiratory Distress
Investigate whether hyperbaric oxygen therapy treatment can become a viable treatment option for COVID-19. If successful, providers will be able to provide future COVID-19 patients with mild-to-moderate respiratory distress…
- Trial name
- HBOT (NCT04800120)
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Malignant Brain Neoplasm
Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI
This trial looks to study the safety and feasibility of using oxygen-enhanced molecular MRI to understand how cancer cells use oxygen differently than normal cells.
- Trial name
- NCT04460495
- Testing
- Arterial Spin Labeling Magnetic Resonance Imaging, pH-Weighted amine CEST, Oxygen-weighted SAGE-EPI
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma
Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma
This clinical trial is using EF5 to measure the oxygen level in tumor cells of patients undergoing surgery or surgery biopsy for newly diagnosed supratentorial malignant glioma.
- Conditions
- Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma, Adult Anaplastic Oligodendroglioma, Adult Diffuse Astrocytoma
- Trial name
- NCT00430079
- Testing
- etanidazole, conventional surgery, pharmacological study
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Cancer Institute (NCI)
Resting Energy Expenditure
Predicting Resting Energy Expenditure in Critically Ill Patients by Measuring Lean Body Mass by US
The study aims to correlate Lean Body Mass (LBM) Evaluated by Musculoskeletal Ultrasound with Resting Energy Expenditure (REE) measured by Indirect Calorimetry and to generate a predictive equation of REE based on LBM, in…
- Trial name
- NCT03193632
- Testing
- US Muscle layer thickness (MLT) estimation, REE estimation by indirect calorimetry
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Eslam Ayman Mohamed Shawki
Oxygen Utilization, Oxygen Kinetics
Mushroom Blend on Oxygen Kinetics
Purpose: To determine the acute effects of a mushroom blend vs. placebo on oxygen kinetics, aerobic power and time to fatigue in healthy adults.
- Trial name
- NCT02075892
- Testing
- Mushroom Blend
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Lung Collapse
HFNC for Induction During Bariatric Surgery Patients.
This study aims to compared the effects of high flow nasal during the induction and during the weaning of anesthesia on intraoperative and postoperative oxygenation and postoperative atelectasis in obese patients undergoing…
- Trial name
- NCT03155711
- Testing
- HFNC group, Standard group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Oxygen Consumption
Tissue Oxygen Use With Combined Arteriovenous Noninvasive Oximetry
The goal of this observational study is to find out if researchers can measure oxygen consumption in the body without having to draw blood from lines in arteries and central veins.
- Trial name
- TOUCAN-1 (NCT06072755)
- Testing
- Finger pulse oximetry probe, Transreflectance oximetry probe
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Respiratory Distress Syndrome, Lower Respiratory Tract Infection
A Low-Resource Oxygen Blender Prototype for Use in Modified Bubble CPAP Circuits
Purpose: Using a novel oxygen blender prototype with modified bCPAP to manage children 1 month to 5 years of age hospitalized with respiratory distress due to lower respiratory tract infection (LRTI) in low-resource settings is…
- Trial name
- NCT04311320
- Testing
- Low-Resource Oxygen Blender
- Where
- Cambodia
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Blood Pressure, Respiration
Verification Protocol for the Cloud DX Vitaliti Continuous Vital Signs Monitor (VERDICT-2)
The VERDICT-2 verification study will examine the accuracy of the Cloud DX Vitaliti Continuous Vital Signs Monitor (Model: CVSM-1A) in an ambulatory context with healthy participants.
- Conditions
- Blood Pressure, Respiration, Pulse Rate, Oxygen Saturation
- Trial name
- VERDICT-2 (NCT05886153)
- Testing
- Vitaliti Continuous Vital Sign Monitor Model CVSM-1A
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Opioid Use Disorder
Hyperbaric Oxygen Treatment (HBOT) During Methadone Tapering
The aims of this study are to 1) explore the efficacy of hyperbaric oxygen therapy (HBOT) applied at two different pressures compared to sham treatment in relieving signs and symptoms (both physical and psychological) of opioid…
- Trial name
- NCT05924022
- Testing
- Hyperbaric Oxygen Treatment Full, Hyperbaric Oxygen Treatment Partial Pressure
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Washington State University
Acute Respiratory Failure
Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness
The objective of this study is to determine the effect of thiamine therapy on oxygen consumption in critically-ill patients. The investigators will evaluate this by measuring VO2 before and after thiamine administration in…
- Trial name
- VO2 (NCT01462279)
- Testing
- Thiamine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center
Cardiovascular Diseases
Virtual Reality-based Therapy and Barriers in Cardiac Patients
The aim of this study is to investigate the chronic hemodynamic and autonomic repercussions of the insertion of VRBT in CR. To qualitatively analyze the perception of patients and physiotherapists regarding the use of VRBT, as…
- Trial name
- NCT04336306
- Testing
- virtual reality-based therapy (VRBT)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Pulmonary Disease, Chronic Obstructive
Single Portable Pulse-dose-conserving Device vs. Combined Use of Stationary and Portable.
Introduction: Portable oxygen devices simplify and facilitate patient therapy. This study was designed to compare oxygen saturation and patient satisfaction with a portable oxygen concentrator or with a combined system consisting…
- Trial name
- NCT02079753
- Testing
- Inogen, Combination system of a portable and a stationary device.
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- Hospital Son Espases
Hypercapnic Respiratory Failure
Use of Nasal High Flow Oxygen During Breaks of Non-invasive Ventilation for Patients With Hypercapnic Respiratory Failure
Chronic respiratory insufficiency and COPD are the third leading cause of death worldwide. Patients decompensate at various stages of their disease and exhibit acute-on-chronic respiratory failure (ACRF), a frequent cause of ICU…
- Trial name
- HIGH FLOW ACRF (NCT03406572)
- Testing
- HFHO Group, Standard O2
- Where
- France
- Volunteers
- 161 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dental Cares
Use of 50% Nitrous Oxide / 50% Oxygen Premix in Primary Care Dental Centers
A 50% nitrous oxide / 50% oxygen premix is administrated to the patient during the realization of dental cares. This openly clinical trial is done in 36 French primary care dental centers, especially on anxious and phobic…
- Trial name
- NCT00643838
- Testing
- Kalinox 170 bar
- Where
- France
- Volunteers
- 549 people
- Sponsor
- Air Liquide Santé International
Pulmonary Disease, Chronic Obstructive, Hypercapnia
Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients
Humidified Nasal High-flow with Oxygen (HNHF-O2) therapy has been reported to have acute beneficial effects in patients with hypoxemic respiratory failure who have been hospitalized.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Hypercapnia, Hypoxia
- Trial name
- NCT03221387
- Testing
- Humidified nasal high flow with oxygen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Temple University
Asthma, Helium
Use of Heliox Associated With PEEP in Patients With Asthma
In patients with obstructive lung disease like asthma aerosol therapy is the most used for drug administration. A order to make better use of aerosolized drugs in asthmatic patients, studies focus on ways to optimize this…
- Conditions
- Asthma, Helium, Oxygen, Positive End-Expiratory Pressure
- Trial name
- NCT01268462
- Testing
- Heliox+PEP, Oxygen+PEP, Heliox
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Pernambuco
Acute Hypoxemic Respiratory Failure, Acute Hypercapnic Respiratory Failure
Closed-Loop O2 Use During High Flow Oxygen Treatment of Critical Care Adult Patients (CLOUDHFOT)
High flow nasal oxygen therapy (HFNO) is an established modality in the supportive treatment of patients suffering from acute hypoxemic respiratory failure.
- Conditions
- Acute Hypoxemic Respiratory Failure, Acute Hypercapnic Respiratory Failure, Respiratory Depression, Respiratory Failure
- Trial name
- CLOUDHFOT (NCT06374589)
- Testing
- Closed-loop FiO2 controller, Conventional
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Interstitial Lung Disease
Clinical Impact of HOME Oxygen SATURation Measurement (SATURHOME)
The use of saturometry at home is more and more widespread in patients suffering from interstitial pulmonary diseases (IPD), the patients seeing it as reassurance and a concrete way to follow the evolution of their disease.
- Trial name
- SATURHOME (NCT04624191)
- Testing
- Saturation at home
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University