Clinical trials: Oxytocin
Birth Outcomes, Labor Pain and to Reduce Pain
The Effect of the Intrapartum Care Model Given in Line With WHO Recommendations on the Birth Process and Care
This study aimed to evaluate the effects of the intrapartum care model provided in line with the World Health Organization (WHO) recommendations on labor pain, fear, comfort, duration, oxytocin use and perception of midwifery…
- Conditions
- Birth Outcomes, Labor Pain and to Reduce Pain, Fear of Birth, Birth Comfort
- Trial name
- NCT06681675
- Testing
- The group that applied the Intrapartum Care Model
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Postpartum Hemorrhage, Twin
Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy
Postpartum hemorrhage (PPH) due to uterine atony is a major cause of maternal morbidity and mortality. Uterotonic drugs are used to improve the muscle tone of the uterus after birth and these are effective at reducing the…
- Trial name
- NCT04025658
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Leiomyoma
Hemostatic Effect of Intrauterine Instillation of Oxytocin in Hysteroscopic Myomectomy
There is no previous study on the hemostatic effect of intrauterine instillation of oxytocin in hysteroscopic myomectomy. All previous studies focused on intravenous administration of oxytocin.
- Trial name
- oxytocin (NCT04996498)
- Testing
- Oxytocin, sterile bacteriostatic water ampule
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Induction of Labor Affected Fetus / Newborn
Early Versus Late Amniotomy Following EAB Cervical Ripening
The objective of this study is to investigate the course of labor in early versus late amniotomy following balloon cervical ripening in women undergoing term induction of labor stratified by parity.
- Trial name
- NCT04216628
- Testing
- Amniotomy
- Where
- Israel
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Healthy
Effects of Intranasal Oxytocin and Stress on Belief Updating
To investigate the effect of 24IU intranasal oxytocin on belief updating when people in stress or non-stress condition.
- Trial name
- NCT03597893
- Testing
- Oxytocin
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Beijing Normal University
Loneliness
Oxytocin-augmented Cognitive-behavioral Group-based Short-term Intervention for Loneliness
The purpose of this study is to evaluate the clinical potential of oxytocin (OT) as an adjunct to a cognitive-behavioral group-based shortterm intervention for participants suffering from loneliness.
- Trial name
- NCT04137432
- Testing
- Oxytocin nasal spray
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Oxytocin, Massage
Effect of Oxytocin Massage and Music on Breastfeeding
The aim of this study is to examine the effect of oxytocin massage and music performed immediately after birth on breastfeeding.
- Conditions
- Oxytocin, Massage, Music, Breastfeeding
- Trial name
- NCT05059028
- Testing
- Oxytocin massage AND music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Learning Disabilities
Effects of Oxytocin on Reinforcement Learning
The main aim of the study is to investigate whether intranasal oxytocin (24IU) influences reward sensitivity and performance monitoring during reinforcement learning.
- Trial name
- NCT03846271
- Testing
- intranasal oxytocin
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Premature Rupture of Membranes
FOLCROM Trial: Foley Catheter in Rupture of Membranes
Multicenter randomized clinical trial comparing oxytocin versus oxytocin and foley catheter for induction in women who present with premature rupture of membranes who are not in labor.
- Trial name
- FOLCROM (NCT01973036)
- Testing
- Foley Catheter, Oxytocin
- Where
- 5 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Social Interaction
Oxytocin and Non-verbal Communication
In this protocol registration, the investigators plan a secondary data analysis of a dataset to explore the effects of intra-nasal oxytocin on the non-verbal expression of affiliation.
- Trial name
- NCT03228901
- Testing
- Oxytocin
- Where
- Australia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Yale-NUS College
Sustained Positive Emotions, Sustained Positive Behavior Change
Study of Wellness Behaviors as a Function of Oxytocin vs Placebo
The specific aim of this study is to test whether oxytocin (OT) boosts the positive emotion yield of a new wellness behavior (Lovingkindness meditation or Mindfulness meditation) and thereby increases nonconscious motives that…
- Trial name
- NCT01929161
- Testing
- Oxytocin, Lovingkindness Meditation, Mindfulness Meditation
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pregnancy Related
Effects of HypnoBirthing Training and Oxytocin Massage in Primiparous Pregnants
This study was conducted to determine the effects of hypnobirthing training and oxytocin massage on birth and postpartum period in primiparous pregnant women.
- Trial name
- NCT06325839
- Testing
- HypnoBirthing training and oxytocin massage group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Giresun University
Oxytocin, Estrogen
Dissecting the Role of Estradiol in Mediating Gender-specific Anxiolytic and Prosocial Effects of Oxytocin
The study aims to examine a behavioral and neural framework for understanding the sex-specific effects of the neuropeptide oxytocin (OXT).
- Conditions
- Oxytocin, Estrogen, Fear Extinction, Emotion Processing
- Trial name
- ESMory (NCT04330677)
- Testing
- Oxytocin nasal spray, Estrogen Gel
- Where
- Germany
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Prenatal Stress
Measuring Outcomes of Maternal COVID-19-related Prenatal Exposure
The rapidly spreading coronavirus Covid-19 pandemic is a major concern worldwide and Italy is at the forefront of this emergency.
- Trial name
- MOM-COPE (NCT04540029)
- Testing
- Maternal stress
- Where
- Italy
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Postpartum Bleeding
Postpartum Uterotonic Administration
The investigators are planning to determine the effect of the timing of oxytocin administration on the amount of blood loss, necessity for additional medical or surgical interventions.
- Trial name
- NCT02495272
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Pregnancy, Labor Pain
Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes
Fetal heart rate patterns are an important parameter in the diagnosis of non-reassuring fetal status. Combined-spinal epidural analgesia is a method of initiating labor analgesia used by approximately 90% of the parturients at…
- Trial name
- NCT02121184
- Testing
- Routine oxytocin, Half-dose oxytocin
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Healthy
Does Oxytocin Modulate Rewarding Effects in Women and Fluctuating Across the Menstrual Cycle
The aim of the study is to explore how the rewarding effect of men's verbal compliment is modulated by oxytocin and gonadal hormone in a romantic context.
- Trial name
- NCT03144115
- Testing
- Oxytocin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Eating Behavior
Effect of Intranasal Oxytocin on Appetite and Caloric Intake in Men and Women
Exciting advances have led to the concept that hormones can modulate appetite and food intake. Oxytocin is a peptide hormone that is released in regions throughout the brain, including areas involved in food motivation.
- Trial name
- NCT01513499
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoarthritis, Knee
Validate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic Effects
The goal of this study is to validate the pharmacodynamic model for pain relief from oxytocin at a peripheral site by intravenous infusion targeted at different levels of the drug.
- Trial name
- NCT04435704
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Lactation, Mindfulness
Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU
The purpose of this research is to investigate associations between mindfulness and meditation techniques and changes in maternal breastmilk in the mother pumping for her NICU infant.
- Conditions
- Lactation, Mindfulness, NICU, Breastmilk
- Trial name
- NCT07351799
- Testing
- Standard of Care, Mindfulness-based Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic