Clinical trials: Ozone Therapy
Lipedema, Pain
Effect of Systemic and Local Ozone Therapy in Lipedema
Lipedema is a disease characterized by enlargement of the subcutaneous tissue and is observed only in the female population. Recently, the inflammatory cascade has been suggested to be the initiator of lipoedema and to play a…
- Conditions
- Lipedema, Pain, Activities of Daily Living, Musculoskeletal Ultrasound
- Trial name
- NCT06954870
- Testing
- Ozone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara Etlik City Hospital
Knee Osteoarthritis
Comparison of the Therapeutic Effects of Intra-Articular Injection of Ozone and Corticosteroid in Knee Osteoarthritis
This clinical trial aimed to involve patients aged 40-85 years who had been experiencing knee pain for at least 6 months and had received a clinical diagnosis of knee osteoarthritis through radiologic imaging.
- Trial name
- NCT06328270
- Testing
- Ozone - oxygen Therapy, Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Alveolar Osteitis
Clinical Investigation of the Efficacy of CGF and Ozone in the Treatment of Alveolar Osteitis
The aim of this study is to investigate the efficacy of CGF and Ozone in the treatment of alveolitis and to develop a new treatment protocol that can enable a quick and effective solution of this clinical problem, which…
- Trial name
- NCT04507009
- Testing
- Ozone, CGF, Traditional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ordu University
Ozone Therapy for Covid 19 Pneumonia Patients
Evaluation of Post-covid 19 Patients Who Receive Ozonetheraphy With Thorax CT
It is known that enhances wound healing by oxidative stress and supports immune system besides it is cheap and has not any side effects.
- Trial name
- NCT04789395
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Peri-Implantitis
Ozone Therapy as an Adjunct to the Surgical Treatment of Peri-implantitis
Decontamination procedure is a challenging factor that affects the success of surgical regenerative therapy (SRT) of peri-implantitis.
- Trial name
- NCT03018795
- Testing
- Decontamination of implant surfaces
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Gazi University
Knee Osteoarthristis, Gonarthrosis
Different Ozone Concentrations for Knee Osteoarthritis
Knee osteoarthritis is a common condition that causes pain, stiffness, and difficulty with daily activities. Ozone injection therapy is a minimally invasive treatment that has been increasingly used to relieve symptoms in people…
- Trial name
- NCT07662512
- Testing
- ozone injection
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Sakarya University
Periodontitis, Stage III Periodontitis
Ozone Therapy After Open Flap Debridement in Periodontitis
Periodontitis is a chronic inflammatory disease characterized by the destruction of supporting periodontal tissues. Open flap debridement (OFD) is a commonly used surgical approach for the treatment of deep periodontal pockets…
- Trial name
- OFD-OZONE (NCT07551297)
- Testing
- Open Flap Debridement, Ozone Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Alparslan Dilsiz
Ozone Therapy, Exercise Performance
Effect of Ozone Therapy on Aerobic Exercise Performance
The goal of this clinical trial is to investigate the effect of the ozone therapy applied using the major autohemotherapy method on exercise performance in male healthy individuals.
- Trial name
- NCT06217549
- Testing
- ozone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Neck Pain
Therapy With Paravertebral Oxygen-ozone Injections and Topical Cannabidiol and β-Caryophyllene Patch in Neck Pain
The aim of this study is to compare the effectiveness of combined treatment with paravertebral oxygen-ozone injections and topical patches containing Cannabidiol and β-Caryophyllene in patients with neck pain by evaluating the…
- Trial name
- NCT06099171
- Testing
- Cannabidiol and β-Caryophyllene Patch, Oxygen-Ozone Therapy
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Humanitas Clinical and Research Center
Low Back Pain, Radiculopathy
Effectiveness of Ozone Therapy Versus Pulsed Radiofrequency in Low Back Pain With Radiculopathy
Treatment selection for refractory radicular low back pain is frequently made in the absence of direct comparative evidence between competing minimally invasive options.
- Trial name
- NCT07773428
- Testing
- Intradiscal ozone therapy, Pulsed radiofrequency
- Where
- Oman
- Volunteers
- 69 people
- Sponsor
- Zagazig University
Ozone Therapy, Muscle Damage
Effects of Ozone Therapy on Muscle Damage
The goal of this clinical trial is to determine the effectiveness of different ozone therapy methods in enhancing recovery after muscle-damaging exercise in healthy adults, and to evaluate their impact on biochemical markers of…
- Conditions
- Ozone Therapy, Muscle Damage, Oxidative Stress, Recovery
- Trial name
- NCT07728422
- Testing
- Autohemotherapy, Ozone Sauna Therapy, Ozonated Lavender Oil Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Inonu University
Low Back Pain, Failed Back Surgery Syndrome
The Effect of Epiduroscopy and Ozone Therapy in Patients With Failed Back Surgery Syndrome
The aim of this study is to assess the efficacy and safety of ozone therapy (vs. placebo) applied into the epidural space through epiduroscopy in Patients with Failed Back Surgery Syndrome.
- Trial name
- Epiduroscopy (NCT01172457)
- Testing
- Epiduroscopy with oxygen therapy, Epiduroscopy with ozone therapy
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Radiation Toxicity, Chemotherapeutic Toxicity
Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025
The main objective of this study is to analyze the impact on the health-related quality of life of patients with refractory symptoms, who have been referred to the HUGCDN Chronic Pain Unit for adjuvant palliative treatment with…
- Conditions
- Radiation Toxicity, Chemotherapeutic Toxicity, Chemotherapy-induced Peripheral Neuropathy, Delayed Wound Healing
- Trial name
- EPOOzo (NCT05417737)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Bernardino Clavo, MD, PhD
MEDICATION RELATED OSTEONECROSIS OF THE JAW
OZONE_EXO: Comparative Analysis of Protocols for Dental Exactions in Patients at Risk of MRONJ: Case-control Study
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is also a potentially painful and debilitating condition.
- Trial name
- OZONE_EXO (NCT06072404)
- Testing
- OxigenOzone_Insufflation
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Fibromyalgia Syndrome
Effectiveness of Major Ozone Autohemotherapy in the Treatment of Fibromyalgia Syndrome
Patients who were admitted to the Physical Medicine and Rehabilitation (PMR) outpatient clinic of our hospital between January 2017 and December 2020 and were treated with Major ozone autohemotherapy with a diagnosis of…
- Trial name
- NCT05034770
- Testing
- major ozone autohemotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Emine Dundar Ahi, MD
Periodontitis
Ozone Application in Periodontal Treatment
This clinical trial aims to evaluate the clinical, biochemical and microbiological efficacy of ozone treatment as an adjunct to nonsurgical periodontal treatment (NSPT) in periodontitis patients.
- Trial name
- NCT05971706
- Testing
- Ozone therapy using a device (Ozone DTA Ozone Generator, Denta Tec Dental AS, Norway), Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Biruni University
Chronic Hepatitis B
Efficacy of Medical Ozone Therapy in Patients With Chronic Hepatitis B
The purpose of this study is to verify the effectiveness and safety of medical ozone therapy system in treatment of chronic hepatitis B.
- Trial name
- EMOTCHB (NCT01342185)
- Testing
- medical ozone therapy with tianyi, medical ozone therapy with humares, Diammonium glycyrrhizinate Capsules
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Rotator Cuff Tendinopathy
Comparison of Subacromial Ozone (O2-O3) and Corticosteroid Injections in the Treatment of Rotator Cuff Tendinopathy
Shoulder pain accounts for approximately 16% of all musculoskeletal symptoms. Rotator cuff tendinopathy is the most common cause of shoulder pain.
- Trial name
- NCT05207384
- Testing
- Ozone (O2-O3) injection, Corticosteroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Tennis Elbow
Ozone Therapy in Lateral Epicondylopathy
Lateral epicondylopathy (LE) is a common cause of elbow pain. In the literature, there are few studies evaluating the efficacy of ozone injection in LE. To our knowledge, there is no study comparing it with exercise therapy.
- Trial name
- O2-O3 (NCT07240155)
- Testing
- Ozone treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Dental Implant Placement, Ozone Therapy
Ozone Versus Conventional Socket Disinfection for Primary Dental Implant Stability
This randomized split-mouth controlled clinical trial aims to compare the effects of ozone and conventional implant site disinfection on primary and early secondary implant stability.
- Trial name
- NCT07687680
- Testing
- Ozone Implant Site Disinfection, Conventional Socket Disinfection
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Zeliha Başak Çakır Erdil