Clinical trials: PCO
Polycystic Ovarian Syndrome
The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)
As both medications i.e. CC and letrozole have been shown to be effective in inducing ovulation in PCOS patients, this study was performed in order to evaluate which regime (whether CC or letrozole) is the best to be used as the…
- Trial name
- NCT01577017
- Testing
- Letrozole
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nik Hazlina
Dysmenorrhea Primary, Dysmenorrhea
Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25
85 percent of women of reproductive age experience consistent period cramps/menstrual pain, and 60% indicate that they do not use painkillers to relieve menstrual symptoms; there is a need for natural and non-medicative…
- Conditions
- Dysmenorrhea Primary, Dysmenorrhea, Menstrual Discomfort, Menstrual Problem
- Trial name
- NUTRITION; GYN (NCT06227676)
- Testing
- Cramp Bites by Aunt Flo's Kitchen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cornell University
Stroke, Spinal Cord Diseases
Use of tDCS Stimulation in Neurological and Gynaecological Conditions
The aim of the study is to test the effect of tDCS stimulation on upper and lower limb function in neurological patients and to reduce pain in gynaecological patients.
- Conditions
- Stroke, Spinal Cord Diseases, Nerve Root Disorder, Endometriosis
- Trial name
- tDCS (NCT06891690)
- Testing
- tDSC stimulation
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Polycystic Ovary Syndrome (PCOS) and Sleep Apnea
Polycystic ovary syndrome (PCOS) affects 5-10% of women in the United States. Its onset is usually at the time of puberty with manifestations of menstrual irregularity, hirsutism, and obesity.
- Trial name
- NCT00203996
- Testing
- continuous positive airway pressure (CPAP), depot leuprolide plus estrogen/progestin replacement, pioglitazone
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Polycystic Ovary Syndrome (PCOS)
Protein and Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is a significant public health problem and is one of the most common hormonal disturbances affecting women of reproductive age.
- Trial name
- NCT07158723
- Testing
- Higher protein dietary pattern, Calorie restriction
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Polycystic Ovary Syndrome
Endocrine Disruptors, Toxic and Essential Chemical Elements and Polycystic Ovary Syndrome
Studies have shown that endocrine disruptors (EDs) and toxic and essential chemical elements affect women's reproductive health and may play a role in the development of polycystic ovary syndrome (PCOS).
- Trial name
- NCT06968455
- Testing
- parabens
- Where
- Slovenia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
PCOS, Polycystic Ovary Syndrome
Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion
This study is trying to find out if flutamide (a medication that blocks the effects of testosterone) may help normalize an aspect of pituitary function (specifically, gonadotropin surge generation) in PCOS.
- Trial name
- CRM010 (NCT04597099)
- Testing
- Micronized progesterone, Flutamide, Estradiol patch
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Infertility, Female, Polycystic Ovary Syndrome
Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, Insulin Resistance, Primary Ovarian Insufficiency
- Trial name
- POMODORI (NCT06167135)
- Where
- Hungary
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
PCOS (Polycystic Ovary Syndrome)
Effects of Folic Acid and Vitamin E on Hormones in Polycystic Ovary Syndrome
The goal of this prospective comparative interventional study is to evaluate serum Ezrin levels and investigate the effects of one-month supplementation with vitamin E and folic acid in Iraqi women of reproductive age diagnosed…
- Trial name
- NCT07723443
- Testing
- Vitamin E 400, Folic Acid 5 Mg Oral Tablet
- Where
- Iraq
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Polycystic Ovary Syndrome, PCOS
Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS)
The purpose of this research study is to determine if adding Metformin, a drug that reduces insulin resistance, to birth control pills will reduce the risk of developing type 2 diabetes, high blood pressure.
- Conditions
- Polycystic Ovary Syndrome, PCOS, Insulin Sensitivity
- Trial name
- NCT00682890
- Testing
- metformin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Mullerian Anomaly of Uterus
Prevalence of Mullerian Anomalies in Infertile Women
Mullerian anomalies are congenital structural anomalies in the uterus . Its prevalence is not uncommon .
- Trial name
- NCT03498079
- Testing
- 3D ultrasound
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Polycystic Ovary Syndrome
Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age
The goal of this study is to determine the relative desirability of metformin vs. oral combined hormonal contraceptives (OCs) in treating Polycystic Ovary Syndrome (PCOS) in women of later reproductive age.
- Trial name
- SHK002 (NCT03905941)
- Testing
- Metformin, Oral combined hormonal contraceptives
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
PCOS
High Plasma Level of Long Pentraxin 3 is Associated With Insulin Resistance in Women With Polycystic Ovary Syndrome (PCOS)
In the present study, serum pentraxin 3 level and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS.
- Trial name
- NCT01463969
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Epicardial Adipose Tissue Pcos
Epicardial Adipose Tissue Thickness in Polycystic Ovary Syndrome (PCOS)
The aim of the present study was to search whether epicardial adipose tissue thickness, a predictor of increased cardiovascular risk, increases in PCOS patients or not and, if it does, to analyze the relationship of EATT with…
- Trial name
- NCT01258946
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
PCOS (Polycystic Ovary Syndrome)
LH/FSH, Testosterone, Prolactin, and Ferritin in PCOS Patients in Jordan
Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder impacting women of reproductive age. Characterized by chronic anovulation, hyperandrogenism, and the presence of multiple small ovarian cysts.
- Trial name
- PCOS patients (NCT07112768)
- Testing
- Serum levels of LH, FSH, testosterone, prolactin, and ferritin
- Where
- Jordan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
PCOS, Hyperinsulinemia
Time-restricted Eating to Improve Metabolic Abnormalities in Polycystic Ovarian Syndrome
Polycystic ovarian syndrome (PCOS) is associated with metabolic symptoms such as hyperinsulinemia. Time-restricted eating may reduce serum insulin and improve insulin resistance in patients with PCOS.
- Conditions
- PCOS, Hyperinsulinemia, Insulin Resistance
- Trial name
- TimeMAP (NCT05126199)
- Testing
- Time restricted eating, Normal ad libitum diet
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ruairí Floyd
Ovarian Cysts
Ultrasonographic Evaluation of Ovarian Stromal Vascularity in Women With Polycystic Ovary Syndrome (PCOS)
The most common endocrine condition in reproductive women is polycystic ovary syndrome. It has a prevalence of 5-10%. According to the Rotterdam criteria, oligo/anovulation, clinic or biochemical hyperandrogenism, PCOS morphology…
- Trial name
- NCT05418595
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Usak State Hospital
Polycystic Ovary Syndrome, Menopause
Health Risks and Barriers to Management Across the PCOS Lifespan
The overall objective of the proposed pilot project is to explore health literacy and barriers to management of PCOS across the lifespan and determine whether the cardiometabolic risks of PCOS extend beyond menopause.
- Trial name
- HERBS (NCT05769426)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Polycystic Ovary Syndrome, Hypertension
Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome
Women with androgen excess polycystic ovary syndrome (AE-PCOS) leads to hypertension.
- Trial name
- NCT04327934
- Testing
- GnRH antagonist, GnRH antagonist + MethylTESTOSTERone 5 MG
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Polycystic Ovary Syndrome
Characterization of a Prospective Cohort of Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in premenopausal women. PCOS is characterized by increase levels of testosterone, unwanted hair growth, adiposity, irregular menstrual cycle, and infertility.
- Trial name
- NCT02010814
- Where
- Denmark
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital