Clinical trials: PET-CT
Parkinson Disease, Healthy Volunteer
Evaluation of Neuroinflammation in Parkinson's Disease Using 18F-NOS PET/CT
The research study is being conducted to test how a specialized type of Positron Emission Tomography (PET/CT) scan could potentially be useful in diagnosing or monitoring treatment in people with Parkinson's disease.
- Trial name
- NCT04062526
- Testing
- [18F]NOS
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Lung Carcinoma, Lower Oesophageal Carcinoma
Evaluation of 4D-contrast Enhanced PET-CT in Tumour Volume Definition
The aim of high dose radiotherapy treatment is to deliver enough radiation to the tumour to kill all the cancer cells while at the same time giving a low dose of radiation to the normal parts of the body to reduce the side…
- Conditions
- Lung Carcinoma, Lower Oesophageal Carcinoma, Pancreatic Carcinoma
- Trial name
- NCT02285660
- Testing
- 4D PET-CT Scan, No intervention
- Where
- United Kingdom
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Sarcoidosis, Cardiomyopathies
Diagnostic Potential of PET/MRI in Cardiac Sarcoidosis
The aim of the study is to find better and more specific non-invasive methods to diagnose and stage cardiac sarcoidosis with the use of advanced imaging modalities, simultaneous 3T MRI and PET.
- Trial name
- NCT03561025
- Testing
- 18F-FDG-PET/MRI, 18F-GE180-PET/MRI
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- St. Olavs Hospital
Temporomandibular Joint, Conservative Treatment Therapy
The Use of PET/CT to Evaluate Synovitis in the Temporomandibular Joint (TMJ)
Temporomandibular joint disorders (TMD) are a common musculoskeletal problem with an estimated 40-75 percent of the population reporting at least one sign.
- Trial name
- NCT01471418
- Testing
- PET/CT with 18-FDG
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Prostate Cancer
A Pilot Study of 123I-MIP-1072 SPECT/CT Imaging With Optional Compact Gamma Camera Probe Imaging in Men With Prostate Cancer Undergoing Prostatectomy
This is a single arm, open label study of up to 20 patients with prostate cancer scheduled for prostatectomy at the NIH Clinical Center.
- Trial name
- NCT01279785
- Testing
- 123I-MIP-1072
- Where
- United States
- Sponsor
- Molecular Insight Pharmaceuticals, Inc.
Non Small Cell Lung Cancer, Surgery
Neoadjuvant Afatinib Combination With Chemotherapy for Stage Ⅱa-Ⅲb NSCLC With EGFR Activating Mutation
The recommended adjuvant therapy for stage Ⅱa-Ⅲb Non-small cell lung cancer (NSCLC) were perioperative chemotherapy. The adjuvant or neoadjuvant chemotherapy for early stage lung cancer improved about 5% 5-year survival.
- Conditions
- Non Small Cell Lung Cancer, Surgery, EGFR Activating Mutation, Chemotherapy
- Trial name
- Neoafa (NCT04470076)
- Testing
- Neoadjuvant treatment: Afatinib, pemetrexed, gemcitabine, cisplatin, carboplatin, Surgical treatment, Adjuvant treatment:afatinib
- Volunteers
- 30 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Atherosclerosis
Non-Invasive Imaging of Atherosclerosis
The purpose of this study is to develop and validate novel magnetic resonance imaging (MRI), dynamic contrast enhanced (DCE)-MRI and positron emission tomography (PET)/MR techniques for the detection and risk stratification of…
- Trial name
- NCT01418313
- Where
- United States
- Volunteers
- 886 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Lymphoma, Large-Cell
Early Evaluation of the Response of Large B Cell Non Hodgkin's Lymphoma to Chemotherapy by PET/CT
Patients affected with non-Hodgkin's large B-cell lymphoma are treated by chemotherapy. The evaluation of the response to this treatment is made by Positron Emission Tomography (PET/CT) in many centres where this technology is…
- Trial name
- NCT00256490
- Testing
- PET/CT 20 days after the first cycle of chemotherapy
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Eric Turcotte
Prostate Cancer, PSMA PET/CT
Brief Title: INTROSPECT: Intraoperative PSMA PET/CT Imaging During Radical Prostatectomy
During prostate cancer surgery, the surgeon aims to remove the tumor completely while preserving the surrounding tissue responsible for urinary continence and sexual potency.
- Conditions
- Prostate Cancer, PSMA PET/CT, Margin Assessment
- Trial name
- INTROSPECT (NCT07829068)
- Testing
- study-specific administration of 68Ga-PSMA-11 followed by ex vivo PET/CT imaging of the prostatectomy specimen
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Clear Cell Renal Cell Cancer (ccRCC), Urothelial Carcinoma (UC)
18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors
The goal of this clinical trial is to evaluate the diagnostic value of CAIX protein specific probe 18F-T2 in PET/CT imaging in participants with solid tumors.
- Conditions
- Clear Cell Renal Cell Cancer (ccRCC), Urothelial Carcinoma (UC), Colorectal Cancer, Cervical Cancer
- Trial name
- NCT07557225
- Testing
- 18F-T2 PET/CT
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Lung Cancer, Solitary Pulmonary Nodule
Liquid Biopsy With PET/CT Versus PET/CT Alone in Diagnosis of Small Lung Nodules
The purpose of this study is to determine if a liquid biopsy, a method of detecting cancer from a blood draw, combined with a PET/CT scan, a type of radiological scan, is better at determining whether a lung nodule is cancerous…
- Conditions
- Lung Cancer, Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
- Trial name
- NCT05066776
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Palo Alto Veterans Institute for Research
Lung Neoplasm, Lymphoma
Comparison of Imaging Characteristics of uEXPLORER and Conventional PET/CT in Patients With Lung Cancer, Lymphoma, and Melanoma
To determine the minimum scan duration for fluorine-18 positron-emitting radioactive isotope-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) scans performed on a total-body PET/CT scanner…
- Conditions
- Lung Neoplasm, Lymphoma, Melanoma, Fluorodeoxyglucose
- Trial name
- NCT04478318
- Testing
- uEXPLORER/mCT, mCT/uEXPLORER
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of California, Davis
Focus of Study is Imaging Performance With the New Technology Compared With the Currently Available Technology.
Pilot Study Intended to Provide Input for Future Designs Using the PET Alpha Ring Detector
A standard PET/CT scanner is comprised of two different machines: An X-ray computed tomography scanner (CT), which gives information about your anatomy, and a Positron Emission Tomography scanner (PET) that provides information…
- Trial name
- NCT01731860
- Testing
- Additional PET Scan
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Philips Healthcare
Localized Prostate Carcinoma
24 Gy in One Fraction Urethral-sparing "HDR Like" SBRT for Prostate Cancer
Patients with prostate cancer who are candidates for stereotactic radiotherapy to the prostate and seminal vesicles will undergo staging exams, which will include prostate specific membrane antigen (PSMA) positron emission…
- Trial name
- PRO-FAST (NCT05936736)
- Testing
- prostate SBRT
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- IRCCS San Raffaele
Coronary Artery Disease
xSPECT-based Myocardial Perfusion Scintigraphy: Consistency of Functional Values and Feasibility of Myocardial Uptake Quantitation in Patients With Suspected Coronary Artery Disease
This study is to evaluate the feasibility of myocardial Standardized Uptake Volume (SUV) assessment by means of X- (Single photon emission tomography) SPECT/Computed tomography (CT), to assess normal reference value under rest…
- Trial name
- xSPECT MPI (NCT04583787)
- Testing
- 99mTc-sestamibi myocardial perfusion SPECT, 82Rb-Chloride myocardial perfusion PET with CCTA
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- University Hospital, Basel, Switzerland
HNSCC
Dose-Effect Relation of Salivary Gland Irradiation
Optimization of radiotherapy to reduce xerostomia is difficult, because many gland locations cannot be seen with current imaging modalities and biological dose-effect are currently insufficiently understood.
- Trial name
- NCT03367780
- Testing
- PSMA PET/CT-scan
- Where
- 3 sites in Netherlands
- Volunteers
- 32 people
- Sponsor
- The Netherlands Cancer Institute
Stable Angina, Coronary Artery Disease
Development and Validation of a Fast, Semi-Automated Hybrid Imaging Platform to Assess Coronary Atherosclerotic Plaque Morphology, Endothelial Shear Stress and Arterial Inflammation: A Proof of Principle Study (VALID-PET-CT)
Imaging the inside of coronary arteries (intravascular imaging) offers great insight into the assessment and treatment of coronary artery disease.
- Trial name
- VALID-PET-CT (NCT04205110)
- Testing
- PET-CT
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Barts & The London NHS Trust
Metastatic Breast Cancer
Study to Determine the Utility of FES-PET in the Prediction of Response to Fulvestrant in Women With Estrogen Positive Metastatic Breast Cancer
Effects of fulvestrant on the ERs may be evaluable by molecular imaging using positron emission tomography with the ER-specific FES tracer.
- Trial name
- NCT03507088
- Testing
- Fluoroestradiol (18F)
- Where
- 2 sites in China
- Volunteers
- 36 people
- Sponsor
- Zhimin Shao
Cancer
68Ga-HSA PET/CT Imaging for Protein-losing Enteropathy
In this project, based on the DTPA-HAS kit, investigators plan to develop a positron nuclide 68Ga labeled DTPA-HSA molecular probe in order to obtain high sensitivity, signal-to-noise ratio and high-resolution PET/CT imaging…
- Trial name
- PLE-PET (NCT06716788)
- Testing
- 68Ga-HSA
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Cancer Hospital & Institute
Non-small Cell Lung Cancer
Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer
The goal of this randomized clinical trial is to learn about if carbon ion radiotherapy dose boost in hypoxia lesions detected by 18F-Misonidazole PET/CT could improve clinical outcomes in locally advanced non-small cell lung…
- Trial name
- NCT06205927
- Testing
- Standard carbon ion beam radiotherapy, Carbon ion beam radiotherapy simultaneously dose boost
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Jian Chen
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.