Clinical trials: PTSD
Depression, Postpartum, Depression
Interpersonal Treatment Program to Prevent Depression and Post-Traumatic Stress Disorder in Low-Income Pregnant Women With Partner Abuse
This study will evaluate the effectiveness of an interpersonally oriented treatment program called Reach Out for a Safe Environment in preventing depression and post-traumatic stress disorder in low-income pregnant women who have…
- Trial name
- NCT00602732
- Testing
- The Reach Out for a Safe Environment (ROSE) program, Enhanced care as usual (ECU)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Appetitive Aggression, Post-traumatic Stress Disorder
Intervention to Support the Reintegration of Former Combatants and Soldiers
The project aims to investigate if trauma-related disorders and appetitive aggression can be reduced in former ex-combatants in DR Congo when a specific intervention (Narrative Exposure Therapy for Forensic Offender…
- Trial name
- NCT01624987
- Testing
- NET for Forensic Offender Rehabilitation (FORNET): a variant of Narrative Exposure Therapy, Control group
- Where
- Republic of the Congo
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Post Traumatic Stress Disorder
Does a Follow-up Appointment Help Parents of Children on PICU?
The aim of our study is to determine the feasibility of carrying out a randomized controlled trial (RCT) to investigate whether screening parents of children admitted to pediatric intensive care unit (PICU) so as to target…
- Trial name
- PICUfu (NCT01628263)
- Testing
- Follow up Clinic for High risk participants
- Where
- United Kingdom
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Emotion Regulation, Cognitive Control
The Effects of Exercise on Emotion Regulation and Cognitive Control in PTSD
The goal of this study is to investigate the effects of a single bout of aerobic exercise on neurophysiological indices of emotion regulation and cognitive control in individuals with clinically significant PTSD symptoms.
- Conditions
- Emotion Regulation, Cognitive Control, PTSD
- Trial name
- NCT05643716
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Post-traumatic Stress Disorder (PTSD)
CB1 Receptor PET Imaging Reveals Gender Differences in PTSD
The objective of the proposed translational study is to test a model, based upon basic science studies, exploring multisystem impairments in PTSD including endocannabinoid (eCB) and glucocorticoids in the modulation of fear…
- Trial name
- NCT02237677
- Testing
- Positron emission tomography (PET) imaging
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Post Traumatic Stress Disorder (PTSD)
Whole Body Hyperthermia & Combat-Related Posttraumatic Stress Disorder (PTSD)
Combat-related post traumatic stress disorder (PTSD) has become an increasingly pressing public health problem in the United States following the overseas wars of the last decade.
- Trial name
- PTSD + WBH (NCT02077972)
- Testing
- High intensity whole-body infrared heating
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Complex Post-Traumatic Stress Disorder
Context Sensitivity in Emotion Regulation in Post-Traumatic Stress Disorder
This study will examine context sensitivity, composed of two sequential elements: (a) accurate classification of changing affective contextual demands, followed by (b) flexible selection of regulatory strategies that matches…
- Trial name
- NCT06007612
- Testing
- Context Sensitivity in Emotion Regulation
- Where
- Israel
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Gal Sheppes
Major Depressive Disorder, Post-Traumatic Stress Disorder (PTSD)
PET Imaging of mGLuR5 With Drug Challenge
This study is designed to look at that involvement of a process in the brain called the glutamate system in depression. Participants will undergo a screening session, up to two functional Magnetic Resonance Imaging (fMRI) scans…
- Trial name
- NCT01691092
- Testing
- Ketamine
- Where
- 3 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Yale University
Sexual Abuse of Child (If Focus of Attention is on Victim)
A 1-year Program to Treat Children Who Have Been Victims of Child Sexual Abuse
Our goal in this study is examine if a program designed to decrease the severity of Post-Traumatic Stress Disorder symptoms in sexually abused children between the ages of 8-12 was effective.
- Trial name
- NCT02181751
- Testing
- Trauma Focused Cognitive Behavioural Therapy Group
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Little Warriors
Post Traumatic Stress Disorder, Alcohol Use Disorder
FAAH Availability in Psychiatric Disorders: A PET Study
The aim of the present study is to examine Fatty Acid Amide Hydrolase (FAAH) availability in humans, including healthy individuals and across a spectrum of psychiatric disorders in which alterations in the endocannabinoid system…
- Conditions
- Post Traumatic Stress Disorder, Alcohol Use Disorder, Psychosis
- Trial name
- NCT04404712
- Testing
- [11C]MK-3168
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
PTSD, Depression
National Guard Outreach and Linkage to Treatment
This project will add an evaluation/research component to an existing peer outreach program, now implemented for over 1100 soldiers in the Michigan Army National Guard. Preliminary work will be completed in three areas.
- Conditions
- PTSD, Depression, Reintegration, Veterans Health
- Trial name
- NCT01020981
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Family Satisfaction, Healthcaregiver Satisfaction
Benefits of the Involvement of Nurses in Meetings Between Physicians and the Families of Patients in the ICU.
When a patient is admitted to the ICU this often happens so suddenly that this can create a significant amount of stress and anxiety for family members for several reasons.
- Conditions
- Family Satisfaction, Healthcaregiver Satisfaction, Family PTSD, Family HADS
- Trial name
- NEWS (NCT01745406)
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fondation Hôpital Saint-Joseph
Post-Traumatic Stress Disorder
Effectiveness of a Web-based Intervention for Guardians of Children Whose One Parent Has Murdered the Other
This study will determine whether a specialized Web site geared for the guardians of children whose one parent has murdered the other can increase guardian capabilities, reduce guardian stress, and improve child behavior and…
- Trial name
- NCT00737035
- Testing
- Interactive Healthcare Communication Application, Control Web sites
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Post Traumatic Stress Disorder
Using Adhesive Biosensor Patches to Characterize the Biochemical Phenotype in PTSD
A psychiatric diagnosis of post-traumatic stress disorder (PTSD) is currently based mainly on non-quantitative elements, such as interviews and subjective impressions.
- Trial name
- NCT04071132
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nadav Goldental
Anxiety, PTSD
Evaluation of the H.O.O.V.E.S. Healing Intensives Program
The aim of this study is to measure the impact of these H.O.O.V.E.S. healing intensives on Veteran participants using several psychological instruments.
- Conditions
- Anxiety, PTSD, Depression
- Trial name
- NCT06300255
- Testing
- H.O.O.V.E.S. Healing Intensives
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- VA Salt Lake City Health Care System
Posttraumatic Stress Disorder
Stepped Care for Children After Trauma: Optimizing Treatment
Children who are exposed to traumatic events are at risk for developing PTSD and other mental health problems. Although effective treatments for childhood PTSD exist, service delivery approaches that are more accessible…
- Trial name
- NCT02537678
- Testing
- Stepped Care TF-CBT, Standard TF-CBT
- Where
- 6 sites in United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Post Traumatic Stress Disorder, Anxiety
Level and Predictors of Trauma-symptoms Among Health Workers and Public Service Providers During the COVID-19 Outbreak
The aim of this study is to investigate the levels of trauma and mental symptoms (i.e., depression and anxiety) among health workers and public service providers during the strict social distancing government-initiated…
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT04374097
- Where
- Norway
- Volunteers
- 1,778 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Post-Traumatic Stress Disorder
Neurobiological Correlates of Post Traumatic Stress Disorder (PTSD) During Rapid Eye Movement (REM) Sleep
The overarching aim of this Exploratory/Developmental Research Grant Award (R21) is to explore the neurobiological correlates of PTSD during REM sleep by using state-of-the science positron emission tomography (PET) sleep…
- Trial name
- REM-P (NCT00871650)
- Testing
- Sleep data recording, PET scan - waking, PET scan - REM Sleep
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
PTSD, Anxiety, Post Traumatic
Xyrem for Treatment Refractory Insomnia Due to PTSD
Xyrem (sodium oxybate) is an agent with the propensity to improve slow wave sleep and sleep efficiency. It is FDA approved to treat cataplexy (drop attacks) associated with narcolepsy (sleep attacks).
- Trial name
- NCT00330291
- Testing
- Xyrem
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Post-Traumatic Stress Disorders
Treatment of NLP Method in Women Who Have Experienced Postpartum Post Traumatic Stress Dissorder
The purpose of this interventional study is to evaluate the effectiveness of the NLP PTSD protocol in the event of PPPTSD. The study's main hypothesis is that the implementation of the NLP protocol will be effective and result in…
- Trial name
- NLP (NCT02730806)
- Testing
- NLP
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yfat Weinstein-Zohar