Clinical trials: Pacemaker
Pacemaker DDD, Cardiopulmonary Endurance
Effect of Standardized Exercise on Cardiopulmonary Function in Patients With Permanent Pacemaker Implantation
The purpose of this study is to observe the changes of cardiopulmonary endurance in patients with pacemaker implantation after long-term exercise, to explore the significance of exercise on patients with pacemaker implantation…
- Trial name
- NCT04957771
- Testing
- Supervise and guide regular exercise
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University Third Hospital
Aortic Aneurysm, Aortic Diseases
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels
As potential biomarkers of pressure-related aortic damage, matrix metalloproteinases (MMP) have been implicated in the pathogenesis of aortic aneurysm because of the important role they play in connective tissue homeostasis.
- Conditions
- Aortic Aneurysm, Aortic Diseases, Pacemaker DDD
- Trial name
- NCT03727542
- Testing
- adjustment of atrioventricular delay in DDD packers
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Arrhythmias, Cardiac
SIELLO Pilot Study for Comparison of Steroid Versus Non-Steroid Pacing Leads
This investigation is designed to demonstrate the clinical efficacy and safety of the low-dose drug of the SIELLO leads in comparison to the non-steroid BPPU leads in a clinical investigation.
- Trial name
- NCT01000532
- Testing
- SIELLO JT/T, Pacemaker therapy, BPPU JT/T
- Where
- Hungary
- Volunteers
- 88 people
- Sponsor
- Biotronik SE & Co. KG
Pacemaker Indication
Master Study for the Investigation of Safety and Efficacy of the EVIA Pacemaker
The objective of this study is to prove the safety and efficacy of the EVIA pacemaker. Primarily, the newly implemented Atrial Capture Control algorithm is evaluated, which automatically measures the right atrial threshold and…
- Trial name
- NCT00916344
- Testing
- EVIA Pacemaker
- Where
- France
- Volunteers
- 175 people
- Sponsor
- Biotronik SE & Co. KG
Tricuspid Regurgitation, CIED Implantation
3D Transthoracic Echocardiographic Evaluation on Tricuspid Regurgitation Progression and Clinical Outcomes in Patients With Cardiac Implantable Electronic Device
The goal of this observational study is to learn about the development and worsening of tricuspid regurgitation (TR) in patients who have cardiac implantable electronic devices (CIEDs).
- Conditions
- Tricuspid Regurgitation, CIED Implantation, Leadless Pacemaker, Pacemaker
- Trial name
- 3DECHO-TR (NCT07793916)
- Testing
- 3D Transthoracic echocardiographic evaluation
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Samsung Medical Center
Diastolic Function, Cardiac Output
Impact of Pacing Mode and Diastolic Function on Cardiac Output
Background It is known from previous research that in patients with complete AV (atrioventricular) block and pacemaker stimulation stroke volume and cardiac output are higher with AV-synchronous than with AV-dyssynchronous…
- Conditions
- Diastolic Function, Cardiac Output, Pacemaker Stimulation Mode, Stroke Volume
- Trial name
- PADIAC (NCT04068233)
- Testing
- Pacemaker stimulation mode
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kepler University Hospital
Pacemaker DDD, His Bundle Pacing
Pacing to Maintain Physiologic Ventricular Activation
Right ventricular pacing causes ventricular dyssynchrony and may be associated with impaired outcome. In the last decade, several approaches for more physiological pacing became available and were implemented in the latest…
- Conditions
- Pacemaker DDD, His Bundle Pacing, LBB Area Pacing, Pacing-Induced Cardiomyopathy
- Trial name
- Pace-Conduct (NCT04416958)
- Testing
- cardiac implantable electronic device (CIED) implantation
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Klinikum-Fuerth
Leadless Pacemaker
Aveir Leadless Pacemaker Japan PMS
The primary purpose of the PMS is to collect safety information on the Aveir DR leadless cardiac pacemaker (LP) system in a population indicated for de novo dual-chamber pacing.
- Trial name
- NCT07106788
- Testing
- Aveir DR Leadless Pacemaker Implant, Single-chamber atrial Aveir patients, Upgrades
- Where
- 14 sites in Japan
- Volunteers
- 304 people
- Sponsor
- Abbott Medical Devices
Prolonged QT Interval
Effects Rapid Atrial Pacing Has on the Electrocardiogram (ECG) in Patients With Dual Chamber Pacemakers
The purpose of this study is to learn what effect rapid atrial pacing (in patients with dual chamber pacemakers) will have on the electrocardiogram including the QT Interval.
- Trial name
- NCT00883610
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vanderbilt University
Patent Foramen Ovale, Cardiac Implantable Electronic Device
Patients With Patent Foramen Ovale and Endocardial Device Leads on Apixaban for Prevention of Paradoxical Emboli
Patients with a patent foramen ovale in the setting of endocardially placed cardiac implantable electronic devices such as pacemakers, defibrillators, or resynchronization therapies are likely at higher risk for paradoxical…
- Trial name
- PARADOX (NCT02378623)
- Testing
- Apixaban
- Where
- United States
- Sponsor
- Mayo Clinic
Cardiac Implantable Electronic Devices
National Tunisian Registry of Cardiac Implantable Electronic Devices
The National Tunisian Registry of Cardiac Implantable Electronic Devices is an observational, prospective and multicenter study aiming to assess the epidemiological, clinical and therapeutic profile of cardiac implantable…
- Trial name
- NATURE-CIED (NCT05361759)
- Testing
- Cardiac Implantable Electronic Devices
- Where
- Tunisia
- Volunteers
- 1,518 people
- Sponsor
- Dacima Consulting
Heart Failure
Choosing the Right Pacing Mode in Heart Failure - The CHOICE Trial
The aim of the study is to see if biventricular pacemakers offer any advantage over conventional pacemakers in patients with heart failure who require pacemakers.
- Trial name
- CHOICE (NCT00875732)
- Testing
- Bi Ventricular Pacing, Right Ventricular Pacing
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- University of Dundee
Dilated Cardiomyopathy, Pediatric
Resynchronization Therapy in Young Patients With and Without CHD
Pacemakers can be attached to one or more than one of the heart chambers. After watching pacemakers work over time, doctors have found that the pacemakers that stimulate only one chamber of the heart sometimes lead to problems…
- Trial name
- NCT00208806
- Testing
- congestive heart failure patients
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Defibrillators, Implantable, Heart Failure With Reduced Ejection Fraction
Multi-centre Observational Registry on Patients With Implantable Devices Remotely Monitored
Multicentric, observational, retrospective registry including patients underwent implantable device implantation (pacemaker or ICD) for any indication in the period from 2009 to 2016, followed by remote monitoring.
- Conditions
- Defibrillators, Implantable, Heart Failure With Reduced Ejection Fraction, Arrythmia, Pacemaker
- Trial name
- IMPLANTED (NCT03061747)
- Testing
- Assesment of outcome of implantable device patients
- Where
- 6 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Azienda Ospedaliera Cardinale G. Panico
Atrial Fibrillation, Atrial Tachyarrhythmia
LEAF - Low Energy In Atrial Fibrillation
The purpose of the study is to demonstrate the efficiency on AT / AF prevention and termination of a new algorithm contained in the Medtronic AT500 Antitachycardia device in patients with conventional pacemaker indications.
- Trial name
- NCT00157781
- Testing
- Medtronic AT500
- Volunteers
- 237 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
TAVI
Does Permanent Pacemaker Status Confer Mortality Benefit in the Short Term Post TAVI
Pacemaker requirement in the immediate post procedure phase following TAVI is approximately 20% depending on device type and patient characteristics.
- Trial name
- NCT02700633
- Testing
- Pacemaker
- Volunteers
- 4,000 people
- Sponsor
- Royal Sussex County Hospital
Pacemaker, Implantable Cardioverter-defibrillator
Ultrasound-guided Axillary Vein Access Versus Cephalic Venous Cutdown for Implantation of Cardiac Electronic Devices.
Venous access is a fundamental step in lead insertion for endovenous cardiac implantable electronic devices (CIED). Cephalic vein cutdown is the most widely used technique in Europe.
- Trial name
- NCT04649788
- Testing
- Ultrasound-guided axillary vein access, Cephalic vein access
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Arrhythmias, Cardiac
Clinically Indicated Magnetic Resonance Imaging in Patients With Cardiac Devices
Patients with implanted cardiac devices who meet appropriate entrance criteria undergo clinically indicated Magnetic Resonance (MR) Imaging Studies using an established safety protocol.
- Trial name
- NCT01130896
- Where
- United States
- Volunteers
- 1,509 people
- Sponsor
- Johns Hopkins University
Heart Diseases
APPROPRIATE - Rate Adaptive Pacing Sensor
The APPROPRIATE study will compare differences in functional capacity (peak VO2) between chronotropically incompetent patients randomized to receive rate responsive pacing driven by either the minute ventilation…
- Trial name
- APPROPRIATE (NCT00757666)
- Testing
- Rate adaptive pacemaker
- Where
- 2 sites in United States
- Volunteers
- 566 people
- Sponsor
- Boston Scientific Corporation
Heart Block, Heart Block Complete
Effect of Site of Right Ventricular (RV) Pacing on RV Function, Left Ventricular (LV) Dyssynchrony and Contraction Efficiency
To evaluate RV systolic function and LV mechanical dyssynchrony and function in different lead position in the RV during permanent pacemaker implantation by using speckle tracking echocardiography (STE) and 3D volumetric ejection…
- Conditions
- Heart Block, Heart Block Complete, Systolic Function
- Trial name
- NCT06636851
- Testing
- Pacemaker and defibrillator
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- South Valley University