Clinical trials: Paediatrics
Sickle Cell Disease, Sickle Cell Anemia in Children
Development of a Provider-Focused Intervention to Improve Health Outcomes in Pediatric Sickle Cell Disease
The goal of this interventional study is to learn about the impact of an intervention for health care providers that teaches individuation and perspective-taking (IPT) skills to enhance patient-centered communication in pediatric…
- Conditions
- Sickle Cell Disease, Sickle Cell Anemia in Children, Sickle Cell Disease (SCD), Sickle Cell
- Trial name
- NCT07540767
- Testing
- Individuation and Perspective-Taking (IPT), pediatric SCD pain management education session
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Pneumonia, Meningitis
Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New Guinea
The National Health Plan 2001-2010 calls for investigation of the feasibility of pneumococcal vaccines for Papau New Guinea. The Papua New Guinea (PNG) Institute of Medical Research, the Telethon Institute for Child Health…
- Conditions
- Pneumonia, Meningitis, Otitis Media
- Trial name
- NCT00219401
- Testing
- Pneumococcal 7 valent conjugate vaccine (Prevenar®)
- Where
- Papua New Guinea
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Papua New Guinea Institute of Medical Research
Lung Diseases
Transmitted Lung Pressures With Biphasic Chest Cuirass
This study will examine the correlation between the transpulmonary pressure and the actual setting on the biphasic chest cuirass device is the primary study end point.
- Trial name
- NCT03799588
- Testing
- Biphasic Chest Cuirass
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Respiratory Tract Infections
ProbioKid as Prevention Among Kids With Frequent URTI
This study was designed to evaluate the preventive efficacy of a 6-week prophylactic administration of Probiokid® on the incidence of respiratory infections and related complications in frequently sick children.
- Trial name
- NCT04525040
- Testing
- ProbioKid®, Pragmatic comparator
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Tumor
Role of Tumoral Biomarker B3 Adrenergic Receptor in Paediatric Solid Tumours
Childhood cancers are the third leading cause of death among children between the ages of 1 and 4, and the second leading cause of death among children aged 5-14 years.
- Trial name
- NCT06312150
- Testing
- Analysis of peripheral blood (control group), Analysis of biological sample (Substudy-solid neoplasms), Analysis of biological sample (substudy-leukaemia patients)
- Where
- 3 sites in Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meyer Children's Hospital IRCCS
Emergence Agitation
Melatonin for Pediatric Emergence Agitation
efficacy of melatonin premedication on emergence agitation in children undergoing herniorrhaphy surgeries
- Trial name
- NCT05223010
- Testing
- Melatonin 5 MG/15 ML Oral Solution 0.05 mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.2mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.4mg/kg
- Where
- Egypt
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Dental Trauma
Laser Doppler Flowmetry in Assessing the Vitality of Traumatised Teeth
Teeth injuries are considered one of the most challenging events that occur in dentistry, especially in children. After an injury, there is a possibility that the blood supply to the tooth may become affected and compromised…
- Trial name
- NCT03005197
- Testing
- Laser Doppler Flowmetry
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Infant Behavior, Child Behavior
Integrated Model for Promoting Parenting and Early School Readiness in Pediatrics
This study tests a comprehensive approach to the promotion of school readiness in low-income families, beginning shortly after the birth of the child, through enhancement of positive parenting practices (and when present…
- Conditions
- Infant Behavior, Child Behavior, Parenting, Child Rearing
- Trial name
- NCT02459327
- Testing
- Video Interaction Project, Family Check Up
- Where
- 2 sites in United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- New York University
Pediatric Medication
The Effect of the Virtual Escape Room Method on Pediatric Drug Administration Knowledge, Self-Efficacy, Clinical Comfort, and Anxiety in Nursing Students: A Randomized Controlled Study
Children are particularly vulnerable to injuries resulting from medication errors due to the severity of the illness, the need for high-risk drugs with a narrow therapeutic range, and the frequent use of intravenous infusions.
- Trial name
- Pediatric Drug (NCT06981403)
- Testing
- virtual escape room game-based pediatric medication management education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Safety Issues
Paracetamol Hypothermia Children
Transient Acetaminophen Induced Hypothermia in Pediatrics Population Undergoing General Anesthesia
- Trial name
- NCT04608669
- Testing
- Paracetamol
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint George Hospital
Chronic Kidney Disease
Does a Mainstream Summer Camp Experience Improve Pediatric Kidney Patients' Physical Fitness and Self Concept?
Purpose: Most children and adolescents with chronic kidney disease (CKD) have much less physical endurance than their age matched peers, are at high risk for premature cardiovascular disease, and have a poor self image in part…
- Trial name
- NCT02803541
- Testing
- 12 day mainstream summer camp experience
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Resuscitation, Pediatrics
Reducing Medication Errors and Time to Drugs Delivery During Pediatric Cardiopulmonary Resuscitation: a Multicenter RCT
The investigators recruit nurses working in 5 swiss Pediatric Emergency Departments or divisions to prepare continuous infusions of vasoactive drugs during a simulation-based pediatric CPR cardiac arrest scenario.
- Trial name
- NCT03021122
- Testing
- PedAMINES™ / Conventional Method, Conventional Method / PedAMINES™
- Where
- 6 sites in Switzerland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Influenza
Immunogenicity and Safety of FluBlok Trivalent Recombinant Hemagglutinin Influenza Vaccine in Healthy Pediatrics
The purpose of this study was to evaluate dose-related safety, reactogenicity and immunogenicity of FluBlok trivalent recombinant baculovirus-expressed hemagglutinin influenza vaccine, administered to healthy children aged 6 to…
- Trial name
- NCT00336453
- Testing
- Influenza Vaccination
- Where
- 3 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Protein Sciences Corporation
Acute Respiratory Tract Infection, Otitis Media
Broad Implementation of Outpatient Stewardship
Reducing inappropriate antibiotic use is a key strategy to mitigate antibiotic resistance and adverse health effects associated with antibiotic exposure.
- Conditions
- Acute Respiratory Tract Infection, Otitis Media, Pharyngitis, Acute Sinusitis
- Trial name
- BIOS (NCT05127161)
- Testing
- Broad Implementation of Outpatient Stewardship (BIOS) intervention
- Where
- 5 sites in United States
- Volunteers
- 1,032 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Intravenous Access
Point of Care UltraSound (POCUS) Use for Intravenous Catheter Placement During Pediatric Interfacility Transport
This study will determine the efficacy of POCUS (Point of Care UltraSound) for intravenous (IV) access during pediatric interfacility transport. The Butterfly iQ+ (Lightning) device will be used.
- Trial name
- NCT04875988
- Testing
- Butterfly iQ+ Ultrasound, Traditional
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Influenza
Safety Study of CSL Limited's Influenza Virus Vaccine in the Paediatric Population Aged >= 6 Months to < 18 Years
A Phase IV, Open Label, Multi-Centre Study to Evaluate the Safety and Tolerability Profile of CSL Limited's Influenza Virus Vaccine in a Paediatric Population Aged >= 6 Months to < 18 Years
- Trial name
- NCT00825162
- Testing
- CSL Limited Influenza Virus Vaccine
- Where
- 7 sites in Australia
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- Seqirus
Anxiety, Virtual Reality
Efficacy of a Preoperative Virtual Reality Intervention as a Paediatric Anxiety Improvement Strategy
This study evaluate the effectiveness of the Virtual Reality Educational Program (RVEP) in the Paediatric Surgical Prehabilitation Unit to reduce the perioperative anxiety in children who undergo to elective surgery.
- Trial name
- NCT03578393
- Testing
- Virtual Reality Educational Program
- Where
- Spain
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Servei Central d'Anestesiologia
Pneumococcal Infections
Study Evaluating 13-valent Pneumococcal Conjugate Vaccine in Healthy Infants in India
The purpose of this study is to assess the safety, tolerability and immunogenicity of a 13-valent pneumococcal conjugate vaccine (13vPnC) compared to Prevenar (7vPnC), when given concomitantly with routine paediatric vaccinations…
- Trial name
- NCT00452790
- Testing
- 13-valent Pneumococcal Conjugate Vaccine, 7 valent pneumococcal conjugate vaccine
- Where
- 12 sites in India
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Oral Mucositis
Effect of Black Mulberry Lollipop on Prevention of Oral Mucositis in Children
THE EFFECT OF BLACK MULBERRY LOLLIPOP AND SODIUM BICARBONATE USED IN ORAL CARE ON PREVENTION OF ORAL MUCOSITIS AMONG CHILDREN RECEIVING CHEMOTHERAPY DUE TO CANCER
- Trial name
- NCT04800549
- Testing
- Oral Mucositis
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Sapanca Ilce Devlet Hastanesi
Children with Undergoing Rehabilitation
Virtual Reality Implantation in Paediatric Rehabilitation (IMPLANT-VR4 CHILD)
Virtual Reality Implementation in Paediatric Rehabilitation (IMPLANT-VR 4 CHILD) Virtual Reality (VR) and Active Video Games (AVG) are promising devices for children in need of rehabilitation.
- Trial name
- IMPLANT-VR4 (NCT06627049)
- Testing
- Focus group, Implementing facilitating strategies, Interviews
- Where
- 2 sites in France
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Fondation Ildys