Clinical trials: Paediatrics
Clotting and Bleeding Disorders, Child Development
Determination of ClotPro Paediatric Reference Range Study
A new thromboelastometry analyser (ClotPro, Enicor GmbH, Munich, Germany) with improved technology was developed. This device has an improved new-generation viscoelastometric testing technique and enables the detection and…
- Conditions
- Clotting and Bleeding Disorders, Child Development, Infant Development, Coagulopathy
- Trial name
- NCT04190615
- Testing
- thromboelastometry test (TEM test)
- Where
- Slovakia
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- National Institute of Children's Diseases, Slovakia
HIV
HIV Point-of-Care Test Evaluation in Infants
HIV Point-of-Care tests in Babies Study (BABY) - Operational evaluation of HIV Point-of-Care tests for very early infant HIV diagnostics in infants born to HIV infected mothers in Mbeya, Tanzania.
- Trial name
- BABY (NCT02545296)
- Testing
- In-vitro Diagnostics
- Where
- Tanzania
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- Michael Hoelscher
Safety Issues
Paracetamol Hypothermia Children
Transient Acetaminophen Induced Hypothermia in Pediatrics Population Undergoing General Anesthesia
- Trial name
- NCT04608669
- Testing
- Paracetamol
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint George Hospital
Paediatric Airway Management
Airway Management Practice Patterns in Paediatric Anaesthesia: A Survey
Respiratory adverse events continue to be the leading reason for perioperative critical events in children. It is crucial for the anaesthesiologist to anticipate, recognize and treat these respiratory adverse events.
- Trial name
- SUR-AMPA (NCT02810288)
- Testing
- Voluntarily response all items in the questionnaire.
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Health Education, Sudden Infant Death
Study of the Impact of Parental Note Taking on the Effectiveness of Anticipatory Guidance
The delivery of anticipatory guidance is an essential component of pediatric practice. Given the large amount of information to be shared during each encounter and the limited time available, there is a need for an effective and…
- Trial name
- NCT01014169
- Testing
- Note taking
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Fever
Non-inferiority Trial of Conditional vs Universal Follow up for Children With Fever in Democratic Republic of Congo
Providers in integrated Community Case Management (iCCM) programs in low resource settings often see children without any danger signs, presenting with fever but not having pneumonia, malaria, or diarrhea.
- Trial name
- NCT02595827
- Testing
- Conditional Advice
- Where
- Democratic Republic of the Congo
- Volunteers
- 4,451 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Immunization
Testing Educational Materials in a Paediatric Setting
Immunization procedures are a common source of iatrogenic pain for infants. A recently developed clinical practice guideline, led by Taddio et al., created evidence-based strategies for management of immunization pain.
- Trial name
- NCT01713322
- Testing
- Pain management education, No pain management education
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Preoperative Anxiety
A Mobile Application for Child-focused Perioperative Education
The investigators developed a child-friendly mobile application to support accessible, interactive patient/caregiver education about pediatric tonsillectomy.
- Trial name
- NCT06054282
- Testing
- "Ready for Tonsillectomy" educational mobile application
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Wheelchairs
Wheelchair Skills Training for Children and Youth
Manual wheelchair (MWC) skills training is a critical component of wheelchair service provision. However, children and youth receive little to no training.
- Trial name
- NCT05564247
- Testing
- Wheelchair Skills Training Program (WSTP)
- Where
- 3 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
Pediatric Obesity
Primary Care Pediatrics Learning Activity and Nutrition With Families
This study is designed to translate an evidence-based family-based weight loss treatment for childhood obesity (FBT) into primary care settings using co-located interventionists to serve as a model for care delivered within a…
- Trial name
- PLAN (NCT02873715)
- Testing
- Family-based treatment, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Mindfulness
Mindfulness and Executive Functions for Prediction of Non-technical Skills of Students in Pediatric Medical Simulations
Medical simulation is a technique that creates a situation or environment to allow persons to experience a representation of a real event for the purpose of practice, learning, evaluation, testing or to gain understanding of…
- Trial name
- MindExSim (NCT03761355)
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Hearing Impairment
Speech-Evoked Auditory Potentials: Multisite Pediatric Evaluation
The goal of this study is to evaluate the sensitivity of a newly-developed prototype device in its ability to measure brain responses to speech sounds in an infant population.
- Trial name
- SEFR (NCT07392164)
- Testing
- A newly developed prototype device for speech-evoked EFR Measurement
- Where
- 3 sites in Australia, Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Susan Scollie
Resuscitation, Shock
Pediatric Fast Fluid Trial 2
The purpose of this study is to determine which of two commonly used methods of manual pediatric fluid resuscitation (The "Push-Pull Technique" vs.
- Conditions
- Resuscitation, Shock, Fluid Therapy, Pediatrics
- Trial name
- PFFT2 (NCT01774214)
- Testing
- Push-Pull technique, Disconnect-Reconnect Technique
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster Children's Hospital
Premature Birth
Studying Newborns' Brain Activity in the NICU Through a Musical Intervention: the Role of Fundamental Frequency
This research project stands to the intersection of neonatology, neuroscience, and music based interventions (MBIs), exploring the impact of structured sound on the brain activity of premature newborns in Neonatal Intensive Care…
- Trial name
- FunFreqNICU (NCT06398912)
- Testing
- Music Based Intervention
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Pediatric Dental Anxiety
Effects of AI-Generated Animated Videos on Dental Anxiety in Children
The goal of this clinical trial is to evaluate the overall effect of an artificial intelligence-generated, instrument-specific animated video series compared with the conventional Tell-Show-Do (TSD) technique on dental anxiety in…
- Trial name
- AIVDAC (NCT07596771)
- Testing
- AI-Generated Animated Video Series, Tell-Show-Do (TSD) Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Obesity
Media Use in Preschooler Study (MUPS)
Childhood obesity is an epidemic and increasing. There are very few effective treatments for obesity in children. Recent studies have shown an association between obesity and sedentary behaviors such as television, video viewing…
- Trial name
- NCT00959309
- Testing
- Strategies to decrease screen time in children, Non-Strategical Media Education
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Asthma
A Patient-Centered Asthma Management Communication Intervention for Rural Latino Children
The purpose of this research is to develop and evaluate an mHealth communication intervention designed to improve asthma medication adherence amongst rural Latino children in South Carolina.
- Trial name
- NCT04633018
- Testing
- AsthmaMD mobile application, Usual care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Airway Disease
Airway Pressure and Lumen Changes During NIV With Flexible Bronchoscopy
Introduction: The non-invasive ventilation (NIV) of continuous nasopharyngeal O2 with intermittent close/open nose and abdomen compression (PO2-NC-AC) can provide effective oxygenation, ventilation and circulation.
- Trial name
- NCT03666403
- Testing
- NIV rate: 0/min, NIV rate: 10-20/min, NIV rate: 5-10/min
- Where
- 2 sites in Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Glaucoma
Comparison Between Handheld Rebound Tonometer and Applanation Tonometer in IOP Measurement in Paediatric Glaucomas
To compare the accuracy between handheld rebound tonometer \& applanation tonometer in IOP measurement in pediatric glaucoma cases
- Trial name
- NCT06766799
- Testing
- Rebound and Applanation Tonometer
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Sohag University
Mpox (Monkeypox), Vaccination
Phase 3 Infant Safety & Immunogenicity Trial of MVA-BN® in DRC
This Phase 3 double-blinded, randomized study aims to evaluate the safety and immunogenicity of the two-dose MVA-BN mpox vaccine regimen, administered subcutaneously, in infants and children aged 4 to 24 months in the Democratic…
- Conditions
- Mpox (Monkeypox), Vaccination, Immunogenicity, Safety
- Trial name
- PregInPoxVac (NCT06844487)
- Testing
- MVA-BN standard regimen, MVA-BN half-dose regimen
- Where
- Democratic Republic of the Congo
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Jean-Pierre Van geertruyden