Clinical trials: Pain, Chronic Disease
Cerebral Palsy, Neurologic Disorder
Neural Mobilization and Cerebral Palsy
Objective: To assess the effect of neural mobilization applied to the lower limbs, compared to conventional physical therapy, in children diagnosed with Cerebral Palsy.
- Trial name
- NEUROREHAB (NCT06485830)
- Testing
- Neural mobilization of the lower limb, Conventional physical therapy
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- University of Seville
Spinal Spondyloarthropathies, Axial Spondyloarthritis
Diagnostic Criteria in the Diagnosis of Spinal Spondyloarthropathies in Patients With Chronic Low Back Pain (Study P05320)(COMPLETED)
This is a multi-national, multi-site, observational study to determine which of two strategies, when used by referring physicians is superior in the diagnosis of axial spondyloarthritis (AS) by rheumatologists.
- Trial name
- NCT00726765
- Volunteers
- 1,090 people
- Sponsor
- Merck Sharp & Dohme LLC
Chronic Pain
Repetitive Thinking in FibroMyalgia and Attentional Bias
Theoretical models of chronic pain hypothesize a privileged treatment of pain-related information that would be the basis of avoidance behaviors in chronic pain.
- Trial name
- PRFM-BA (NCT03466892)
- Testing
- Questionnaires and computer paradigm
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Stroke
Subacromial Space in Chronic Stroke Patients
This study aims to examine the subacromial space, shoulder pain, and shoulder disability in chronic stroke patients. A total of 60 chronic stroke patients aged 40-65 with similar demographic characteristics are planned to be…
- Trial name
- NCT07139665
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Ankara University
Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Prostatitis
Chemokine Mechanisms in Chronic Pelvic Pain
The purpose of this study is to identify biomarkers that can be utilized in the diagnosis of chronic pelvic pain syndrome in men.
- Trial name
- NCT01676857
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Sciatica, Lumbar Radiculopathy
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Chronic low back pain is a common and disabling condition that affects millions of people in the United States. Many people with chronic low back pain do not get enough relief from current treatments.
- Conditions
- Sciatica, Lumbar Radiculopathy, Lower Back Pain, Degenerative Disc Disease
- Trial name
- NCT04982965
- Testing
- Active Cannabis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Fibromyalgia, Chronic Widespread Pain
Comparison of Multidimensional Parameters in Women With Fibromyalgia and Healthy Controls
Fibromyalgia (FM) is a chronic, widespread pain syndrome affecting 2-6.6% of the population and significantly impairing quality of life.
- Trial name
- NCT07416097
- Testing
- Clinical and Questionnaire-Based Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Chronic Pain
CANPAIN Feasibility Study Pragmatic Real World Trial Investigating CBMP in Chronic Pain Patients
The CANPAIN study has been devised to evaluate the efficacy and safety of a defined cannabis based medicinal product (CBMP) delivered by inhalation to patients with non cancer chronic pain attending a private clinic.
- Trial name
- CANPAIN (NCT05288010)
- Testing
- Cannabis
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Harley Street (CPC) Limited
Whiplash Injury
Whiplash-associated Disorders - Needling Treatments Pilot Study
This pilot study is being conducted to provide proof of concept for three recently developed needling treatments, in the treatment of whiplash associated disorder type 2 (WAD-II).
- Trial name
- NCT01824810
- Testing
- Intramuscular Stimulation, myoActivation, Neural Prolotherapy
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Fibromyalgia, Chronic Pain
Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain
While acute pain after surgery or trauma comes on suddenly and lasts for a limited amount of time, chronic pain persists and can continue for months and even years.
- Conditions
- Fibromyalgia, Chronic Pain, Depression
- Trial name
- NCT00524420
- Testing
- rTMS
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Washington
Musculoskeletal Diseases, Chronic Pain
Wellness Through Mobile Health
This pilot project will evaluate the potential of an affordable smartphone app to improve users' mental well-being.
- Conditions
- Musculoskeletal Diseases, Chronic Pain, Anxiety Disorders, Depression
- Trial name
- NCT04640090
- Testing
- Smartphone app (Wysa)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Neck Pain
Development of a Self-administered Neck Mobility Assessment Tool in Chronic Neck Pain Patients.
This study evaluates, if the movement of the cervical spine, assessed via a specific questionnaire by the patient, is a valid and reliable tool and could be used in daily clinical routine.
- Trial name
- NCT02754934
- Testing
- Cervical range of motion
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Balgrist University Hospital
Diabetic Peripheral Neuropathic Pain
Study of the Safety and Efficacy of RGH-896 in Patients With Diabetic Peripheral Neuropathic Pain
This study is designed to evaluate the safety and efficacy of RGH-896 in patients with diabetic peripheral neuropathic pain.
- Trial name
- NCT00838799
- Testing
- RGH-896, pregabalin
- Where
- 54 sites in United States
- Volunteers
- 458 people
- Sponsor
- Forest Laboratories
Breast Cancer, Breast Cancer Female
Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial
The LOLIPOP Trial is a large (n=4,300 patients) pragmatic, international, multicentre, prospective, randomised, double blind, placebo-controlled, parallel assessment, safety and effectiveness superiority study.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Conserving Surgery, Mastectomy
- Trial name
- LOLIPOP (NCT05072314)
- Testing
- lidocaine 2% and 10%
- Where
- 49 sites in Australia, Hong Kong and 2 more
- Volunteers
- 4,300 people
- Sponsor
- Monash University
Sedentary Lifestyle, Knee Osteoarthritis
NEAT!2 Sedentary Behavior Reduction for Individuals With Past or Present Knee Symptoms, Injuries, or Surgeries
This study will evaluate the effectiveness of an mHealth sedentary reduction program over a 6-month period of time in adults with past or present knee symptoms, injuries, or surgeries.
- Conditions
- Sedentary Lifestyle, Knee Osteoarthritis, Knee Injuries, Knee Pain Chronic
- Trial name
- NCT03987932
- Testing
- NEAT!2, NEAT!2+Calls, Delayed NEAT!2
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Fibromyalgia Syndrome, Fibromyalgia
Can a Relaxometer Improve Cognitive Impairment of Fibromyalgia Patients
The aim of the study is to evaluate the differences in cognitive performance and quality of life, after a cycle of treatment with the relaxometer, between a group of patients affected by fibromyalgia and a control group.
- Conditions
- Fibromyalgia Syndrome, Fibromyalgia, Pain, Chronic, Impairment
- Trial name
- Fibrorilax (NCT04170387)
- Testing
- Relaxometer
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Prostatitis
The Efficacy and Safety of OM-89 in Patients With Recurrent Chronic Prostatitis/Chronic Pelvic Pain Syndrome
This study is planned to Evaluate the Efficacy and Safety of OM-89 in Patients with Recurrent Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
- Conditions
- Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Chronic Prostatitis, Chronic Pelvic Pain Syndrome
- Trial name
- NCT06345014
- Testing
- OM-89 [Uro-Vaxom® Capsule]
- Where
- South Korea
- Volunteers
- 332 people
- Sponsor
- AJU Pharm Co., Ltd.
Trigeminal Neuralgia
Regional Anesthesia in Refractory Trigeminal Neuralgia: 21 Cases Reported to the Limoges University Hospital
Trigeminal neuralgia is defined according to the third edition of the International Classification of Headache Disorders (ICHD-3) criteria. Chronic pain can have a major impact on the quality of life.
- Trial name
- TRINEB ONE (NCT03669744)
- Testing
- telephone survey
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Limoges
Recurrent Acute Pancreatitis, Chronic Pancreatitis
Soy Tomato Juice to Improve Outcomes in Pancreatitis
This goal of this clinical trial is to see if people with recurrent acute pancreatitis or chronic pancreatitis can tolerate and regularly drink a tomato juice beverage.
- Trial name
- STOP (NCT07447687)
- Testing
- Soy-tomato juice product, Will include a soy-tomato juice product to be consumed during the 4 week intervention phase. A total of about 12 ounces (administered in two small cans) of the juice will be consumed
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Ohio State University
Pain, Chronic Postsurgical, Knee Osteoarthritis
Central Sensitization in Total Knee Arthroplasty Patients with Persistent Pain
Persistent post-surgical pain is a significant adverse effect after total knee arthroplasty, present in around 20% of the patients. Central sensitization may contribute to developing and maintaining pain.
- Conditions
- Pain, Chronic Postsurgical, Knee Osteoarthritis, Sensitization, Central
- Trial name
- NCT05575310
- Testing
- Total Knee Arthroplasty
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- University of Barcelona
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