Clinical trials: Pain, Chronic Disease
Low Back Pain, Disability Physical
Psychological Predictors of Pain and Disability in Patients With Chronic Low Back Pain After Manual Therapy
Low back pain has been reported to cause more disability than any other musculoskeletal health condition worldwide. About eight out of ten people will experience back pain at least once in their lifetime.
- Conditions
- Low Back Pain, Disability Physical, Manual Theapy
- Trial name
- NCT07306312
- Testing
- Manual therapy, Manual therapy plus Pain Neuroscience Education
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Chronic Pain, Obesity
A Mobile Intervention to Reduce Pain and Improve Health (MORPH)
Chronic pain contributes to declining health and function in older adults; effects that are intensified by obesity and sedentary (sitting) behavior.
- Conditions
- Chronic Pain, Obesity, Sedentary Lifestyle
- Trial name
- NCT03377634
- Testing
- MORPH
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
Acute Musculoskeletal Pain, Chronic Pain
The Pain Intervention Via Video Optimization Trial
This project tests a brief evidence-based video to help educate patients regarding effective and safe pharmacologic and non-pharmacologic therapies for acute musculoskeletal pain (MSP).
- Trial name
- PIVOT (NCT06035575)
- Testing
- Educational video
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of North Carolina, Chapel Hill
Neck Pain, Neck Pain Musculoskeletal
The Effectiveness of Dynamic Neuromuscular Stabilization (DNS) Exercises Compared to Localized Exercises and Standard Care on Pain Intensity, Neck Dysfunction, and Upper Cervical Range of Motion in Patients With Chronic Neck Pain: A Pilot Randomized Controlled Trial (RCT)
Many people experience long-lasting neck pain, which can affect daily life, work, and overall well-being. This study aims to find out which type of exercise program is most effective in reducing neck pain, improving neck…
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Chronic Neck Pain, Neck Disease
- Trial name
- DYNEX (NCT07395011)
- Testing
- Dynamic Neuromuscular Stabilization (DNS) Exercises, Local Exercises, Usual Care
- Volunteers
- 45 people
- Sponsor
- Hochschule Osnabruck
Tennis Elbow
Comparative Study Between Different Mobilization Techniques for Patients With Chronic Tennis Elbow
Background: Tennis elbow is a common musculoskeletal disorder affecting the functional activities of daily living through common extensor tendinopathy.
- Trial name
- RCT (NCT06812377)
- Testing
- Maitland joint mbilization, mulligan mobilization, radial nerve mobilization
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Low Back Pain, Chronic Pain
Aging, Mobility and Chronic Low Back Pain
Chronic low back pain (CLBP) is very common in older adults and is one of the most common reasons for disability and poor quality of life.
- Trial name
- "Chronic pain" (NCT05167877)
- Testing
- No intervention will be given to the participants
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Headache, Migraine
Psychological Assessment and Treatment of Chronic Benign Headache
Subjects with chronic migraine or tension headaches will receive 12 sessions of biofeedback or relaxation training after fulfilling screening, intake interviews, \& psychological testing requirements.
- Conditions
- Headache, Migraine, Tension Headache, Stress Headache
- Trial name
- NCT00018811
- Testing
- Relaxation training & thermal biofeedback, Surface EMG biofeedback
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Chronic Cholecystitis, Cholelithiasis
Effect of Vitamin C on Postoperative Pain After Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effect of Vitamine C supplements to be helpful to reduce the postoperative pain after laparoscopic cholecystectomy through the double-blinded randomized controlled trial.
- Trial name
- NCT02553551
- Testing
- Vitamin C
- Where
- South Korea
- Volunteers
- 320 people
- Sponsor
- Taeho Hong
Knee Osteoarthritis, Knee Pain Chronic
The Effect of Physical Therapy Modalities and Kinesio Taping in Patients With Knee Osteoarthritis
Osteoarthritis (OA) is the most common degenerative joint disease with pathological structural and functional disorders all over the world. 27 million patients diagnosed with osteoarthritis in the USA alone.(1-2)
- Trial name
- NCT05211544
- Testing
- physical therapy modalities and exercise, kinesio taping and exercise, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Abant Izzet Baysal University
Endometriosis, Bladder Pain Syndrome
Translational Research in Pelvic Pain
This study aims to better understand the pathways leading to pain in women with two types of pelvic pain condition (endometriosis-associated pain and bladder pain syndrome) and determine whether these pathways can be used to…
- Conditions
- Endometriosis, Bladder Pain Syndrome, Chronic Pain
- Trial name
- TRiPP (NCT04001244)
- Where
- 2 sites in Portugal, United Kingdom
- Volunteers
- 787 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Myofascial Pain Syndromes
Transcranial Magnetic Stimulation and/or Neurofunctional Electrical Acupuncture in Myofascial Chronic Pain Patients
To evaluate the hypothesis: the effects of repetitive transcranial magnetic (rTMS) stimulation and/or peripheral stimulation (neurofunctional electrical acupuncture) treatments are more effective in pain relief than placebo-sham…
- Trial name
- NCT02381171
- Testing
- Active rTMS, Active Neuroacupuncture
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain
The purpose of this study is to evaluate the efficacy of D-Cycloserine versus placebo treatment in reducing pain from urological chronic pelvic pain syndrome (UCPPS).
- Trial name
- UCPPS (NCT02385266)
- Testing
- D-Cycloserine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Northwestern University
Myofascial Pain Syndrome, Fibromyalgia
Validation of a Pressure Pain Threshold Scale in Patients Diagnosed With Myofascial Pain Syndrome and Fibromyalgia
To date, there are no valid and reliable pressure pain threshold scales for use in research or clinical practice. The existing manual palpation protocols and scales have limited support in the literature and our knowledge has not…
- Trial name
- NCT02802202
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- California State University, Dominguez Hills
End Stage Renal Failure, Neuropathic Pain
Qutenza for Critical Ischaemia in End Stage Renal Failure
Critical ischaemia is pain at rest as the result of poor blood flow and lack of oxygen being delivered to the tissues. It normally affects the hands and feet and can be very debilitating.
- Trial name
- NCT01704339
- Testing
- QUTENZA
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Emma Aitken
Pain Management
Comparative Study Between Conventional Radiofrequency Ablation vs Chemical Neurolysis of Ganglion Impar for Treatment of Chronic Non Cancer Related Coccydynia
Aim: compare effectiveness (satisfaction) and duration of pain relief between patients who perform the conventional thermal radiofrequency on the ganglion impar vs patients who perform the chemical neurolysis with alcohol in…
- Trial name
- NCT07247565
- Testing
- Radiofrequency ablation alone, Alcohol injection
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Ain Shams University
Pain, Pain Syndrome
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06072001
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Chronic Physical Health Conditions
MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace
The specific aim of the study is to evaluate the health benefits of a series of group workshops designed for workers with chronic physical health conditions.
- Trial name
- NCT01978392
- Testing
- Self-management group workshops
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- Liberty Mutual Research Institute for Safety
Osteoarthritis
Synvisc to Treat Osteoarthritis of the Temporomandibular Joint
This study will examine the effectiveness of injected hylan (Synvisc) for treating pain associated with osteoarthritis of the temporomandibular joint (jaw joint) and improving function of the joint.
- Trial name
- NCT00078351
- Testing
- High molecular weight hylan (Synvisc) injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Intestinal Obstruction
Intestinal Microbiota and Visceral Pain in Chronic Intestinal Pseudo-Obstruction Syndrome (CIPO)
Chronic Intestinal Pseudo-Obstruction Syndrome (CIPO) is a rare gastrointestinal motility disorder. CIPO evolves through iterative flare-ups that can be triggered by viral or bacterial infections, psychological stress, or…
- Trial name
- METADOLOMIC (NCT06610929)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Periodontal Disease, Chronic Neck Pain
Association Between Periodontal Disease and Chronic Neck Pain
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability.
- Trial name
- NCT07711431
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
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