Clinical trials: Pain, Chronic Disease
Chronic Mechanical Neck Pain
Sensory Motor Control and Muscle Energy Technique for Chronic Mechanical Neck
A randomized controlled trial to evaluate the effectiveness of Sensory Motor Control training combined with Muscle Energy Technique in reducing pain and improving function, cervical range of motion, proprioception, and…
- Trial name
- NCT07681687
- Testing
- Muscle energy technique for MET only group, MET +SMC for experimental group
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Ibadat International University, Islamabad
Pain, Chronic Disease
Medication Adherence Therapy for Opioid Abusing Pain Patients
The purpose of this study is to develop and pilot test a combined behavioral and pharmacological intervention designed to decrease pain, functional interference, and drug abuse while increasing medication adherence.
- Conditions
- Pain, Chronic Disease, Prescription Opioid Abuse
- Trial name
- NCT00249587
- Testing
- Methadone
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Austria Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01667016
- Where
- 8 sites in Austria
- Volunteers
- 305 people
- Sponsor
- Biotronik Vertriebs-GmbH
Interstitial Cystitis, Chronic Interstitial Cystitis
PEMF Therapy to Treat Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to gather information from the investigation of a non-pharmacological (non-drug) treatment known as low frequency pulsed electromagnetic field (PEMF).
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT04540887
- Testing
- Pulsed Electromagnetic Field (PEMF) Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI
Efficacy and Safety of Endovenous Ablation for Relief of Knee Pain in Elderly Patients With Lower Extremity Varicose Veins: A Prospective Observational Study
Lower extremity varicose veins (LEVV) are common among elderly patients and can cause leg heaviness, pain, and swelling. In some older adults, venous congestion may contribute to knee or peri-knee pain, which is often…
- Conditions
- Varicose Veins of Lower Limb, Chronic Venous Insufficiency, CVI, Knee Pain, Knee Osteoarthritis
- Trial name
- EVA-Knee-Elder (NCT07239284)
- Testing
- Endovenous Ablation for Varicose Veins
- Volunteers
- 50 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Complex Regional Pain Syndrome (CRPS)
TARGET Post-Approval Study
The purpose of this prospective, multicenter, single arm post-approval study is to demonstrate continued safety of the Axium and Proclaim Neurostimulator System for dorsal root ganglion (DRG) stimulation.
- Trial name
- TARGET PAS (NCT02800863)
- Testing
- Dorsal Root Ganglion (DRG) Stimulation (Axium™ Neurostimulator System), Dorsal Root Ganglion (DRG) Stimulation (Proclaim™ Neurostimulator System)
- Where
- 44 sites in United States
- Volunteers
- 426 people
- Sponsor
- Abbott Medical Devices
Chronic Sinusitis, Facial Pain Disorder
Sinusitis and Facial Pain Disorders Anti-Depression Trial
The study hypothesis is that the addition of an antidepressant to the standard treatment regimen in patients with both chronic sinusitis and depression or facial pain disorders and depression will decrease the report of chronic…
- Conditions
- Chronic Sinusitis, Facial Pain Disorder, Depression
- Trial name
- SFPAT (NCT00754793)
- Testing
- escitalopram
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Washington
Chronic Pain, Opioid Dependence
Evaluation of Pain Neuroscience Education for Patients Who Experience Chronic Pain With Concurrent Opioid Dependence
Chronic musculoskeletal pain (CMP) is estimated to affect over 100 million adults and is targeted as an instigator of opioid dependence (OpD).
- Trial name
- NCT06442306
- Testing
- Pain Neuroscience Education, General Health Education
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Wichita State University
Neck Pain, Shoulder Pain
Neck and Shoulder Pain Research Study
Pain in the neck and shoulders is a musculoskeletal disorder that affects a significant number of individuals.The aim of this study is to evaluate the effects of PBMT (with a device that combines low level laser therapy and light…
- Conditions
- Neck Pain, Shoulder Pain, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT02940119
- Testing
- Multi Radiance Medical®
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- University of Nove de Julho
Chronic Low-back Pain, Lumbar Facet Joint Syndrome
Comparison of the Effectiveness of Ultrasound-guided Versus Radioguided Medial Lumbar Bundle Branch Block
In adults with chronic low back pain, the investigators will compare the effectiveness of the medial bundle branch block on three lumbar levels (L3-L4, L4-L5 and L5-S1) performed either by radiographic guidance or by ultrasound…
- Trial name
- NCT04658953
- Testing
- Ultrasound guided infiltration, Fluoroscopy guided infiltration
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Pudendal Neuralgia, Neuralgia
Perioperative Medical Program to Optimize Nerve Regeneration After Robot-assisted Laparoscopic Neurolyses of Pudendal and/or Inferior Cluneal Nerves for Chronic Neuralgias: Results After 1-year Follow-up
Pudendal and inferior cluneal neuralgias are responsible for chronic pelvicperineal pain. These two neuralgias are associated in approximately 25% of cases.
- Trial name
- REGEN (NCT06796595)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- UBOSGA
Electromyography, EMG: Myopathy
Electromyographic Study for the Help and Guidance of BoNTA Administration in the Treatment of Chronic Pelvic Floor Pain
Chronic pelvic pain (CPP) is a common presenting complaint affecting approximately 15-40 % of women aged 18-50 in western countries and 5-43% of women in most developing countries.
- Conditions
- Electromyography, EMG: Myopathy, EMG Syndrome, Pelvic Pain
- Trial name
- SEMG (NCT03715777)
- Testing
- Clostridium botulinum type A (BoNTA)
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Jose Alberola-Rubio
Neuropathic Pain, Chronic Pain
Insula Neuromodulation for Chronic Neuropathic Pain
This study will comprehensively investigate the insula as a brain target for neuromodulation to treat chronic neuropathic pain.
- Trial name
- NCT05404581
- Testing
- neuromodulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Virginia
Adenomyosis
Norwegian Adenomyosis Study I
Adenomyosis is characterized by the appearance of endometrial cells in the muscular layer of the uterus. It affects about 15-20% of the female population.
- Trial name
- NAPPED I (NCT02201719)
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Migraine
Head-to-head Study of Erenumab Against Topiramate in Patients With Episodic and Chronic Migraine
This study used a single-cohort, 2-treatment arm, parallel-group randomized, double-blind, double-dummy design in adult patients with episodic migraine and chronic migraine, who had to be either naïve or not suitable for or could…
- Trial name
- HER-MES (NCT03828539)
- Testing
- Erenumab, Topiramate
- Where
- 79 sites in Germany
- Volunteers
- 777 people
- Sponsor
- Novartis Pharmaceuticals
Interstitial Cystitis, Chronic, Painful Bladder Syndrome
Clinical Features and Histologic Findings in Bladder Pain Syndrome/Interstitial Cystitis
Objectives- to find out whether a correlation exists between denudation of urothelium and diagnosic delay in patients with BPS / IC, secondary aim was to search a correlation between impact of symptoms evaluated with ICSI-ICPI…
- Trial name
- HistologyIC (NCT03069053)
- Where
- 4 sites in Italy
- Volunteers
- 57 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Osteoarthritis
Effects of Transcutaneous Electrical Nerve Stimulation on Pain and Disability in Patients With Osteoarthritis
The purpose of this study is to determine the effects of transcutaneous electrical nerve stimulation (TENS) on pain and mobility by comparing different stimulation sitesP: 1. the location with the lowest resistance 2.
- Trial name
- NCT01137266
- Testing
- TENS
- Where
- Netherlands
- Volunteers
- 72 people
- Sponsor
- Maxima Medical Center
Orthopedic Disorder of Spine, Placebo Effect
Clinical Predictive Effects of Mulligan Treatment in Patients With Chronic Neck Pain
The aim of the study is the measurement and comparison of two manual therapy techniques, the Mulligan´s mobilization with movement technique, and de placebo technique, both applicated in patients with subacute neck pain.
- Conditions
- Orthopedic Disorder of Spine, Placebo Effect, Disability Physical
- Trial name
- NCT05004467
- Testing
- Mobilization With Movement Technique
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Universidad Europea de Madrid
Shoulder Pain
Quantitative Analysis of Different Acupuncture Needle Manipulation to Treat Chronic Shoulder Pain
The plan " Quantitative analysis of different acupuncture needle manipulation to treat chronic shoulder pain "includes an objective observation of acupuncture operation (movement in the form of acupuncture needles, intensity…
- Trial name
- NCT03197207
- Testing
- "Dragon and Tiger warring" in lifting and thrusting, "Dragon and Tiger warring" in twisting-rotating
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Migraine, Headache, Block
Pulse Radiofrequency and Occipital Nerve Block for Chronic Migraine Patients
In this study, the effect of nerve blockade and radiofrequency treatment applied to the nerve on pain in chronic migraine patients will be investigated.
- Conditions
- Chronic Migraine, Headache, Block, Occipital Neuralgia
- Trial name
- NCT06247592
- Testing
- Greater occipital nerve block, Greater occipital nerve pulse radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Aydin Adnan Menderes University
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