Clinical trials: Pain, Chronic Post-Surgical
Residual Limb Pain, Stump Pain
Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study
Persistent residual limb pain is common after traumatic amputation and significantly impairs rehabilitation and prosthetic use. Postoperative stump infection may contribute to peripheral nerve sensitization, scar fibrosis, and…
- Conditions
- Residual Limb Pain, Stump Pain, Post-Amputation Pain, Surgical Site Infection
- Trial name
- INF-STUMP-PAIN (NCT07438795)
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Sternotomy Closure,Open Heart Surgery, Cardiac Surgery
Prediction of Chronic Pain in Cardiac Surgery: Evaluation by Algocartography Predict-ALGOCARTE
Sternotomy results in chronic postoperative pain in 30-55% of subjects. Few studies have been published on chronic pain in cardiac surgery, but there appears to be a relationship between the area of peri-scar hyperalgesia, which…
- Conditions
- Sternotomy Closure,Open Heart Surgery, Cardiac Surgery, Chronic Pain Post-Procedural
- Trial name
- Predict-ALGOCA (NCT06681272)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Hospices Civils de Lyon
Chronic Postsurgical Pain
Effect of Oliceridine Patient-Controlled Intravenous Analgesia on Postoperative Chronic Pain After Video-Assisted Thoracoscopic Lung Resection
The primary objective is to evaluate the impact of oliceridine versus sufentanil for perioperative analgesia on the incidence of chronic postsurgical pain (CPSP) with functional impact in patients undergoing video-assisted…
- Trial name
- NCT07018375
- Testing
- Oliceridine, Sufentanil
- Where
- 7 sites in China
- Volunteers
- 320 people
- Sponsor
- Tianjin Medical University General Hospital
Chronic Post Operative Pain, Kidney Transplant; Complications
Post-surgical Chronic Pain After Retroperitoneal Laparoscopic Living Kidney Donor
This study aimed to determine the relationship between the quadratus lumborum and erector spinae plane block technique and the incidence and severity of chronic post-surgical pain in accordance with Brief Pain Inventory Score…
- Conditions
- Chronic Post Operative Pain, Kidney Transplant; Complications, Anesthesia Regional, Laparoscopy
- Trial name
- NCT05572775
- Testing
- Quadratus lumborum (QL) block, Erector Spinae Plane (ESP) Block
- Where
- Indonesia
- Volunteers
- 146 people
- Sponsor
- Universitas Indonesia
Pain Management, Postoperative Acute Pain
Effect of Sedation After Ultrasound-Guided Spinal Anesthesia on Back Pain
This study will evaluate whether giving sedation before spinal anesthesia, when performed with ultrasound guidance, reduces the risk of developing back pain after surgery.
- Conditions
- Pain Management, Postoperative Acute Pain, Chronic Back Pain
- Trial name
- NCT07198412
- Testing
- Ultrasound-guided spinal anesthesia, Midazolam plus ultrasound-guided spinal anesthesia, Landmark-guided spinal anesthesia
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Benha University
Chronic Rhinosinusitis
Early Saline Irrigation to Decrease Post-operative Endoscopic Debridement
Nasal saline is a common treatment adjunct in the post-operative setting for endoscopic sinus surgery. However, the ideal timing and quantity of irrigation in the early post-operative period remains unknown.
- Trial name
- NCT01943370
- Testing
- Early saline irrigation, Routine Irrigation
- Volunteers
- 25 people
- Sponsor
- University of Alberta
Thoracotomy, Chronic Pain
Chronic Pain After Thoracotomy, an Incidence Study in a Single Surgical Center
Investigation of chronic pain frequency after thoracotomy for lung cancer. Risk factors for development of chronic pain are investigated. Questionnaire survey.
- Trial name
- NCT00834769
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Hopital Foch
Chronic Postoperative Pain
Benefit on Chronic Pain of Early Screening and Management of Patients With Persistent Postoperative Pain at 3 Months
Chronic postoperative pain has an overall incidence of approximately 30%, with 5% to 10% of cases classified as severe (numerical rating scale > 6/10).
- Trial name
- DROPS (NCT07160595)
- Testing
- Early management of postoperative pain at 3 months detected using sms
- Where
- 16 sites in France
- Volunteers
- 2,052 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Postoperative Pain, Chronic Post Operative Pain
Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery
The present study compares the Erector Spinae Plane (ESP) block, Pectoral (PECS II) block, and Serratus-Intercostal Fascial Plane (SIFP) block.
- Conditions
- Postoperative Pain, Chronic Post Operative Pain, Breast Tumor, Locoregional Anesthesia
- Trial name
- NCT05185752
- Testing
- SIFP Block Locoregional Interfascial Anesthesic Technique, PECS II block: Locoregional Interfascial Anesthesic Technique, ESP block: Locoregional Interfascial Anesthesic Technique
- Where
- Spain
- Volunteers
- 103 people
- Sponsor
- University of Valencia
Chronic Postoperative Pain, Pediatric ALL
Chronic Postsurgical Pediatric Pain. Evaluation Risk Factors to Develop Chronic Postsurgical Pain in Children and Adolescents Undergoing Surgery in a First Level Hospital
Chronic postsurgical pain had number of prevalence on 20%. Its derivates from risk factors, but recent research provide new potential risk factors to develop chronic postsurgical pediatric pain.
- Trial name
- NCT04735211
- Testing
- Surgery
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Guillermo Ceniza Bordallo
Postoperative Pain, Neuropathic Pain
Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone Requirement
Spinal surgery is associated with intense pain and associated to a history of preoperative chronic pain. Pregabalin is licensed to treat chronic neuropathic pain, particularly when high dose of opioid are required.
- Trial name
- PREGAB (NCT02866396)
- Testing
- Pregabalin, Naive patient
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Christophe Aveline, MD
Post Mastectomy Pain Syndrome, Chronic Pain Following Surgical Procedure for Cancer
Super-voltage PRF of Stellate Ganglion Versus Super-voltage PRF of T2 T3 Sympathetic Ganglia in Managing PMPS.
The aim of this study is to compare the effectiveness of super-voltage pulsed radiofrequency of stellate ganglion and super-voltage pulsed radiofrequency of T2-T3 sympathetic ganglia in the treatment of postmastectomy pain…
- Trial name
- PMPS PRF (NCT07675096)
- Testing
- Group S : Stellate Ganglion supervoltage pulsed radiofrequency, Group T : T2-T3 chains supervoltage pulsed radiofrequency.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute, Egypt
Neuropathic Pain
Donepezil Compared to Placebo in Patients With Chronic Neuropathic Pain
Based on laboratory studies, donepezil will improve pain relief more than placebo in patients with chronic neuropathic pain who are currently taking gabapentin or pregabalin.
- Trial name
- NCT01743976
- Testing
- Donepezil
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Wake Forest University
Chronic Ocular Pain
Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)
The study was designed to demonstrate the safety and efficacy of two dose concentrations of SAF312 eye drops (5 mg/mL and 15 mg/mL) in subjects with CICP persisting at least for 4 months after refractive or cataract surgery and…
- Trial name
- NCT04630158
- Testing
- SAF312
- Where
- 28 sites in United States, Japan and 1 more
- Volunteers
- 153 people
- Sponsor
- Novartis Pharmaceuticals
Total Knee Arthroplasty, Chronic Postoperative Pain
Postoperative Painful Chronicization After Knee Replacement Surgery : Exploratory Study of BDNF's Kinetics
Chronic pain is an extremely disabling disease. It is a major public health problem due to the lack of effective therapy. Chronic postoperative pain (CPOP) is defined by a painful symptomatology in the operated area unrelated to…
- Trial name
- KNEE BDNF (NCT04604847)
- Testing
- blood test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Chronic Scar Pain
Dysport in Post-Surgical Neuralgia
The study is designed to determine whether a currently licensed version of botulinum toxin (Dysport®) is effective for the treatment of pain that has developed and/or persisted for months or years around the scar of a previous…
- Trial name
- PMOD03 (NCT03663101)
- Testing
- Lidocaine, Botulinum toxin type A
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Ipsen
Chronic Postoperative Pain, Open Heart Surgery
Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery
This prospective observational study aims to compare three routinely used postoperative analgesia techniques in patients undergoing open heart surgery: intravenous analgesia, thoracic epidural analgesia (TEA), and bilateral…
- Conditions
- Chronic Postoperative Pain, Open Heart Surgery, Postoperative Analgesia, Analgesia
- Trial name
- TEA-ESPB-IV (NCT07257744)
- Testing
- Intravenous Analgesia, Thoracic Epidural Analgesia (TEA), Erector Spinae Plane Block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Karadeniz Technical University
Ovarian Neoplasm
Impact of Specific Monitoring of Intraoperative Analgesia Under General Anesthesia on Chronic Pain After Ovarian Cancer Surgery
This is a single-center, randomized, phase II, non-comparative, single-blind clinical study that will determine whether morphine reduction through intraoperative monitoring by ANI (Analgesia Nociception Index) significantly…
- Trial name
- MONIALC (NCT04906187)
- Testing
- Arm A : intraoperative ANI monitoring of nociception, Arm B : no specific monitoring of nociception
- Where
- France
- Volunteers
- 126 people
- Sponsor
- Institut Bergonié
Low Back Pain, Opiate Addiction
Study of Opioid Use After Lumbar and Cervical Spine Surgery
The purpose of this project is to assess the impact of an educational video on the use of prescription opioid medication during a 6-month period following spine surgery.
- Conditions
- Low Back Pain, Opiate Addiction, Neck Pain
- Trial name
- SOULCS (NCT02674711)
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Persistent Pain After Delivery
Persistent Pain After CS Delivery
Many factors influence the development of persistent pain after CS (chronic pain) as well as post-partum depression. We are attempting to use trajectory pain methods in an attempt to identify those at risk for the development of…
- Trial name
- NCT01996592
- Where
- United States
- Volunteers
- 575 people
- Sponsor
- Wake Forest University Health Sciences