Clinical trials: Pain, Chronic Post-Surgical
Sexual Dysfunction, Hernia, Inguinal
Pain Related Sexual Dysfunction After Laparoscopic Inguinal Hernia Repair
Previous studies have reported that about 3 % of patients who have had open inguinal herniorrhaphy had a visceral, ejaculatory-related pain.
- Conditions
- Sexual Dysfunction, Hernia, Inguinal, Other Chronic Postoperative Pain
- Trial name
- NCT01086007
- Where
- Denmark
- Volunteers
- 1,172 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Postsurgical Pain, Acute Pain
Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery
Studies evaluating postoperative pain as a risk factor for CPSP are almost exclusively carried out in the context of scheduled surgery.
- Conditions
- Chronic Postsurgical Pain, Acute Pain, Emergency Surgery, Opioid
- Trial name
- POCSE (NCT06555107)
- Testing
- questionnaire, phone call
- Where
- France
- Volunteers
- 693 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pain, Postoperative
Thoracic Paravertebral Block for Postoperative Analgesia After Video-assisted Thoracic Surgery.
The use of paravertebral catheters is a recommended technique to achieve postoperative analgesia after thoracic surgery. To date there is no consensus on which drug regime (local anesthetics with or without opioid) is best.
- Trial name
- PARAVI (NCT01082744)
- Testing
- Ropivacaine + Sufentanil, Ropivacaine
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon
Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative
Neuropathic Pain After Lung Surgery
To understand pain pathophysiology in terms of risk factors and protective mechanisms ranging from molecular pathways to societal impacts.
- Conditions
- Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative, Chronic Chemotherapy-induced Neuropathic Pain, Chronic Chemotherapy-induced Pain
- Trial name
- NCT02960971
- Testing
- Thoracic surgery for lung cancer
- Where
- 2 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Danish Pain Research Center
Persistent Pain, Postoperative Hyperalgesia
Prevention of Persistent Postsurgical Pain After Thoracotomy
Postthoracotomy acute pain is followed by persistent postsurgical pain in 20-30% of the patients, defined as pain that lasts more than 3-6 months after surgery.
- Trial name
- NCT01243801
- Testing
- Ketamine
- Where
- 2 sites in Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Clinic of Barcelona
Inguinal Hernia, Chronic Pain
Trigger-point Blockade in Persistent Pain After Open Groin Hernia Repair
Groin hernia repair is a common procedure performed in approximately 2,000 patients per one million inhabitants. Severe chronic pain following groin hernia repair is seen in 2-5% of the patients indicating that a large number of…
- Trial name
- Trigger-open (NCT02065219)
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Pain Syndrome
Pain After Removal of Mandibular Third Molars With or Without Advanced Platelet-rich Fibrin
Pain is the most common complication following surgical removal of an impacted mandibular third molar. Several risk factors may increase the intensity and duration of pain following removal of mandibular third molars.
- Trial name
- NCT06377839
- Testing
- Advanced platelet-rich fibrin in the ekstraction socket
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Chronic Postoperative Pain
Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome
Breast cancer is considered the commonest malignancy affecting women with an incidence exceeding one million cases per year. Although it has a favorable prognosis with improved lines of treatment, some complications may still…
- Trial name
- NCT06036979
- Testing
- Paravertebral plane block, Erector spinae plane block, Intravenous morphine, ketorlac and paracetamol
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Chronic Postsurgical Pain, Acute Postoperative Pain
Persistent Pain and Its Impact on Daily Life After Lung Surgery
This study will examine how pain changes over the first six months after lung surgery and how it affects daily life. It will include adults scheduled for surgery to remove part or all of a lung.
- Conditions
- Chronic Postsurgical Pain, Acute Postoperative Pain, Pain-Related Functional Interference
- Trial name
- NCT07853456
- Testing
- Longitudinal Assessment of Pain and Pain-Related Functional Interference
- Volunteers
- 350 people
- Sponsor
- Aerospace Center Hospital
Chronic Pain, Surgery
Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain
The investigators will approach elective cardiac and thoracic surgery patients in the preoperative consultation clinic. Consenting individuals will be administered, before surgery validated pain, psychological and sleep…
- Trial name
- CT-Pain (NCT04798573)
- Where
- Canada
- Volunteers
- 10,000 people
- Sponsor
- University Health Network, Toronto
Chronic Pain
Sensory Abnormalities in Post-surgical Peripheral Neuropathy
The concept of normality is a cornerstone in medical practice and research. As an example, in clinical chemistry, a laboratory value based on a plasma sample exceeding the +/- 1.96 x standard deviation (SD) range, referenced from…
- Trial name
- NCT03966677
- Where
- Denmark
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Chronic Back Pain
SCS Programming Study in Treating Intractable Chronic Back Pain (NOVA)
This is an open-label prospective, randomized, controlled, multi-center study comparing DTM-SCS programming approach to Conventional SCS programming approach.
- Trial name
- NOVA (NCT04571242)
- Testing
- DTM Programming, Conventional SCS programming
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- SGX Nova LLC
Pain, Postoperative
Chronic Pain Following Thoracic Surgery
Pain that persists after the healing of a surgical wound has previously been described as an important, but often unrecognized clinical problem.
- Trial name
- PTPS-18 (NCT01144845)
- Testing
- Thoracic surgery
- Where
- Denmark
- Volunteers
- 702 people
- Sponsor
- University of Aarhus
Chronic Pain Syndrome, Thoracotomy
Retrospective Analysis of Factors Affecting Chronic Postoperative Pain After Thoracotomy
The aim of this retrospective study is to determine the factors affecting the development of chronic pain in patients with thoracotomy in the Thoracic Surgery Operating Rooms of İbn-i Sina Hospital.
- Trial name
- NCT05501977
- Testing
- thoracotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Ankara University
Chronic Postsurgical Pain
Effectiveness of Myofascial Release in Patients With Chronic Post Sternotomy Pain Syndrome
The main aim of this study is to investigate the effectiveness of Myofascial release in patients with chronic sternotomy pain.
- Trial name
- NCT06630208
- Testing
- Myofascial release, Breathing exercises, Pharmacological treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Paravertebral Block, Pectoral Nerve Block
Pectoral Nerve Block Versus Paravertebral Block In The Incidence of Chronic Pain After Breast Cancer Surgery
Chronic pain after Mastectomy is frequent and an important healthcare priority because of its effect on quality of life. Although the association between the severity of acute pain after surgery and the likelihood of chronic pain…
- Conditions
- Paravertebral Block, Pectoral Nerve Block, Chronic Pain, Mastectomy; Lymphedema
- Trial name
- NCT06082206
- Testing
- thoracic paravertebral block (TPVB), PECS group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Osteo Arthritis Knee, Chronic Post-operative Pain
Pain Phenotyping in Knee OA: a Pilot Trial
Osteoarthritis (OA) is disease in which the joint breaks down, causing pain. The decision to surgically replace the knee, a procedure called total knee arthroplasty (TKA), depends on x-ray results as well as pain and dysfunction.
- Trial name
- NCT06066684
- Testing
- n/a, observational
- Where
- 2 sites in Canada
- Volunteers
- 55 people
- Sponsor
- University Health Network, Toronto
Postoperative Pain, Chronic Postsurgical Pain
Effect of Erector Spinae Plane Block on Neuropathic Pain After Abdominal Hysterectomy
This study evaluated whether bilateral erector spinae plane block (ESPB) performed before abdominal hysterectomy could reduce postoperative pain and the development of chronic and neuropathic pain.
- Trial name
- NCT07830706
- Testing
- Bupivacaine, Standard Perioperative Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Necmettin Erbakan University
Chronic Pain Syndrome
The Analgesic Efficacy Supra-scapular Nerve RF After Breast Surgery
Eighty patients with chronic shoulder pain after breast surgery were allocated randomly into 2 groups; forty patients received fluoroscopically guided supra-scapular nerve pulsed radiofrequency (PRF) followed by injection of…
- Trial name
- NCT03247842
- Testing
- suprascapular nerve block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University