Clinical trials: Pain, Face
Pain, Stomatognathic Diseases
The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.
The study will determinate influence of four selected physiotherapeutic procedures on the pain intensity and the range of mandibular mobility in patients with myofascial disorders in the SS.
- Conditions
- Pain, Stomatognathic Diseases, Muscle Hypertonia, Myofacial Pain Syndromes
- Trial name
- NCT05021874
- Testing
- Four different physiotherapy treatment
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Myofacial Pain Syndrome, Botulinum Toxin
Botulinum Toxin A in Patients With Myofascial Pain Syndrome With and Without Zinc Supplementation
Research question: Dose the use of oral zinc supplement improve the effects of botulinum toxins injection in patients with myofascial pain dysfunction syndrome? Statement of the problem: MPDS Patients treated with botulinum toxin…
- Trial name
- NCT05605886
- Testing
- Solvazinc 50mg
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Disease, Dental, Pulpitis
Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker
This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent…
- Conditions
- Pulp Disease, Dental, Pulpitis, Reversible Pulpitis, Irreversible Pulpitis (Toothache)
- Trial name
- NCT07452614
- Testing
- vital pulp treatment
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Ghalib Abdul-khaliq
Aging, Face; Atrophy
Fractional Laser Drug Delivery of a Local Anesthetic
The purpose of this study is to assess the clinical efficacy of fractional CO2 laser-assisted delivery of a topically applied anesthetic to the perceived pain during filler injection.
- Trial name
- NCT05734248
- Testing
- Facial filler injection
- Where
- 2 sites in Greece
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Pain, Complications
Evaluation of Satisfaction in Patients Undergoing Non Surgical Lifting by Means of Coned Wires.
An email questionnaire about subjective satisfaction and discomfort has been sent to 243 patients undergoing non-surgical facial and cervical lift 1 week, 1 month, 6 months and 1 year after treatment.
- Trial name
- SCW (NCT02347826)
- Where
- Italy
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- AQ-DE
Pain
Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain
Evaluation of the efficacy and safety of a single dose of an ibuprofen effervescent tablet in the treatment of pain following third molar extraction in comparison to single doses of placebo, standard ibuprofen tablets, and…
- Trial name
- NCT00631111
- Testing
- effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Bruxism, Bruxism, Sleep-Related
Bruxism Therapy of Facial Pain
This prospective, non-profit study aims to better understand how occlusal splints (gnathological splints) affect daytime and nighttime bruxism (teeth grinding) and clenching in adults with chronic myofascial pain of the jaw…
- Conditions
- Bruxism, Bruxism, Sleep-Related, Sleep Quality
- Trial name
- BRUXI (NCT07611643)
- Testing
- Electromyographic analysis of the masseter muscle using the Diabruxo® device (Biotech-Novations, Sanremo, Italy).
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Aging, Pain
RHA® Redensity With New Anesthetic Agent - Perioral Rhytids
This is a randomized, controlled, double-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA® Redensity with new anesthetic agent is non-inferior to RHA® Redensity with lidocaine in…
- Trial name
- NCT04069585
- Testing
- RHA® Redensity with new anesthetic agent, RHA® Redensity with lidocaine
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Pain, Local Infiltration
Pain Perception With a Comfort-ın Jet Injection and Conventional Dental Injection
The investigators aimed to compare the effectiveness of the Comfort-in system, which is a jet injection type, and infiltrative anesthesia with a traditional injector, and to measure the effect of children's anxiety on the…
- Conditions
- Pain, Local Infiltration, Anesthesia, Fear
- Trial name
- NCT04682080
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Pain, Aging
RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)
This is a randomized, controlled, double-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA® Redensity with new anesthetic agent is non-inferior to RHA® Redensity with lidocaine in…
- Trial name
- NCT06378086
- Testing
- RHA® Redensity with new anesthetic agent, RHA® Redensity with lidocaine
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Myofacial Pain
Occlusal Splint and Masticatory Muscle Injection in Myofacial Pain
Myofascial pain is one of the common symptoms in patients with temporomandibular joint disorders. Occlusal splint use, trigger point injections and the combination of this two methods are primary treatment options.
- Trial name
- NCT05228327
- Testing
- Occlusal splint treatment, Masticatory muscle injection, Combination of occlusal splint and masticatory muscle injection treatments
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Pain, Dental Pain
Comparison of Different Pain Rating Scales in Patients With Symptomatic Teeth
Patients with symptomatic teeth who applied endodontic clinic between April 2019 and December 2019 for root canal treatment were enrolled in this study.
- Trial name
- CoPRS (NCT04231955)
- Testing
- numerical rating scale, visual analogue scale, color analogue scale
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Dental Anaesthesia, Dental Pain
Photobiomodulation and Tooth Analgesia
The purpose of this study is to test photobiomodulation (PBM) with a non-invasive light device for reducing discomfort during dental treatments in children.
- Conditions
- Dental Anaesthesia, Dental Pain, Dental Analgesia
- Trial name
- NCT06691269
- Testing
- Photobiomodulation, Topical Benzocaine, Local Anesthesia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Alzheimer Disease, Pain
Recognizing Pain Intensity in Alzheimer's Disease
The most common form of dementia is Alzheimer's disease, with 900,000 people affected in France in 2015 and a forecast of 1.3 million in 2020.
- Conditions
- Alzheimer Disease, Pain, Autonomic Nervous System Disease
- Trial name
- DOMASNA (NCT04614532)
- Testing
- cognitive assessment, Cold Pressor Test, digital sensor of Nociception Level Index
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pain, Postoperative, Pain, Chronic
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).
- Conditions
- Pain, Postoperative, Pain, Chronic, Pain, Acute, Surgical Injury
- Trial name
- NCT04439552
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Dental Pain and Sensation Disorder, Dental Caries in Children
Local Anesthesia With Computerized Device for Restorative Procedures in Pediatric Patients
The aim of the present study is to assess if there are differences on perceived pain during local anesthesia performed with SleeperOne device or with a traditional syringe in pediatric patients.
- Trial name
- NCT05531435
- Testing
- local anaesthetic injection
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Pain
Face Validity and Cross-Cultural Acceptability of the FPS-R in Cameroon
This study evaluates the face validity and cultural acceptability of the Faces Pain Scale - Revised in pediatric patients treated at Mbingo Baptist Hospital, Northwest Province, Cameroon.
- Trial name
- FPS-RCam (NCT02571933)
- Testing
- Pre-treatment Faces Pain Scale - Revised, Post-treatment Faces Pain Scale - Revised, Cognitive interview
- Where
- Cameroon
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cameroon Baptist Convention Health
Healthy
Tolerability Study of the Application of a 3M Microstructure Transdermal System
The purpose of this study is to evaluate the safety and tolerability of an experimental device that introduces microscopic channels into the skin.
- Trial name
- NCT01257763
- Testing
- Transdermal Microchannel Skin System
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Eustachian Tube Dysfunction, Facial Pain
SinuSonic for ETD and Facial Pain: Acoustic Vibration + Oscillating Expiratory Pressure
This study was originally designed with three aims: (1) healthy controls to assess nasal nitric oxide, (2) adults with Eustachian Tube Dysfunction (ETD), and (3) adults with facial pain/pressure.
- Trial name
- NCT04404036
- Testing
- SinuSonic Device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina