Clinical trials: Pain, Labor
Labor Pain
A Comparison Study of Patient Controlled Epidural Analgesia (PCEA) With and Without Basal Infusion Using Ropivacaine 0,15% and Fentanyl μg/ml for Pain Relief in Labor, Assessment of Efficacy and Maternal Satisfaction.
This is a prospective, randomized, double blind study, in which a comparison of patient controlled epidural analgesia (PCEA) of continuous background infusion with demand dose and demand only, using ropivacaine 0,15% and fentanyl…
- Trial name
- NCT02084589
- Testing
- PCEA with basal infusion and demand dose using ropivacaine 0,15% and fentanyl 2μg/ml for pain relief in labor, PCEA without basal infusion (demand only) using ropivacaine 0,15% and fentanyl 2μg/ml for pain relief in labor
- Where
- Greece
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Laboring Women Requesting Neuraxial Labor Analgesia
Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes
The primary objective of this study is to compare the onset and duration of the initial dose of medications given through three different epidural (conventional epidural, combined spinal epidural and dural puncture epidural)…
- Trial name
- NCT02008591
- Testing
- Epidural Technique versus Dural Puncture Epidural Technique versus Combined Spinal Epidural Technique
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brigham and Women's Hospital
Musculoskeletal Pain, Disability Physical
Individual and Work-Related Risk Factors for Musculoskeletal Pain: a Cross-Sectional Study Among Turkish Office Workers
Most studies investigating the risk factors related with musculoskeletal pain have been conducted in European countries and North America, and because of the difference in health, economic, and social systems, their results are…
- Trial name
- NCT04160585
- Testing
- There is no intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Istanbul University - Cerrahpasa
Labor Pain and to Reduce Pain
Can Labor Pain be Reduced by Open Placebo Intervention? A Bayesian Account for Labor Pain
The human nervous system continuously processes a potentially overwhelming stream of signals from bodily senses, which induces uncertainty.
- Trial name
- NCT07077590
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Roi Treister
Migraine, Tension Type Headache
The Efficacy of a Cognitive and Physical Intervention to Reduce Head and Muscle Pain in a Working Community
This study is a controlled, cluster randomised, interventional trial to evaluate the effectiveness of a workplace cognitive and physical program (Intervention), in reducing the frequency of head and neck pain in an extensive…
- Conditions
- Migraine, Tension Type Headache, Cervical Pain
- Trial name
- NCT00551980
- Testing
- Cognitive, Relaxation, Exercise Therapy
- Where
- Italy
- Volunteers
- 2,895 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Labor Pain
Effectiveness of Breathing Exercises During the Second Stage of Labor
To determine effectiveness of breathing exercises for pregnant women during the second stage of labor on maternal pain, duration of labor, dyspnea, oxygen saturation (SPO2) and the first-minute Appearance, Pulse, Grimace…
- Trial name
- NCT04556643
- Testing
- Breathing exercises
- Where
- Pakistan
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Labour Analgesia
Spinal Analgesia in Labour Pain
To evaluate the efficacy and safety of dexmedetomidine as an adjuvant to bupivacain and fentanyl in spinal Analgesia to decreases pain during normal labour
- Trial name
- NCT07332130
- Testing
- injecting dexmedetomidine, injecting mixture of bupivacaine fentanyl
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Minia University Hospital
Labor Pain
Response Patterns to the Electric Stimulation of Epidural Catheters in Term Pregnant Women
Lumbar epidural analgesia is commonly used for labor pain relief due to its effectiveness and safety. Despite its very high success rate, the epidural technique remains a rather blind technique and failures continue to occur.
- Trial name
- NCT02274467
- Testing
- Trans-catheter electric stimulation test
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Transcranial Direct Current Stimulation, Working Memory
Transcranial Direct Current Stimulation Effect on Pain Threshold and Working Memory: Impact of Age and Protocol Type
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation method which has great potential as an aid in the therapeutic management of neuropsychiatric disorders and chronic pain syndromes.
- Conditions
- Transcranial Direct Current Stimulation, Working Memory, Pain
- Trial name
- NCT04328545
- Testing
- Anodal tDCS on DLPFC, Anodal tDCS on M1
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Birth Outcomes, Labor Pain and to Reduce Pain
The Effect of the Intrapartum Care Model Given in Line With WHO Recommendations on the Birth Process and Care
This study aimed to evaluate the effects of the intrapartum care model provided in line with the World Health Organization (WHO) recommendations on labor pain, fear, comfort, duration, oxytocin use and perception of midwifery…
- Conditions
- Birth Outcomes, Labor Pain and to Reduce Pain, Fear of Birth, Birth Comfort
- Trial name
- NCT06681675
- Testing
- The group that applied the Intrapartum Care Model
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Labor Pain, Obstetric Pain
Programmed Intermittent Epidural Bolus (PIEB) Techniques for Labour Analgesia
Epidural Analgesia remains the most effective form of pain relief in labour. After initiating epidural analgesia, there are many epidural drug regimens that can be employed to maintain analgesia for the duration of labour using…
- Conditions
- Labor Pain, Obstetric Pain, Analgesia
- Trial name
- PIEB (NCT06266767)
- Testing
- Levobupivacaine and Fentanyl
- Where
- Qatar
- Volunteers
- 136 people
- Sponsor
- Hamad Medical Corporation
Labor Pain
Combined Spinal/Epidural (CSE) Saline Duration/Spread
An attempt is being made to see if by injecting a set volume of sterile saline into the epidural space during the treatment of labor pain with a combined spinal/epidural (CSE) increases the amount of pain relief obtained and…
- Trial name
- NCT01062893
- Testing
- Sterile normal saline 0 mls, 15 mls sterile normal saline
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Wake Forest University Health Sciences
Anesthetic, Sedative or Analgesic Complications in Labor or Delivery
Trial of Onset of Epidural Pain Relief With Low Dose Bupivacaine and Different Doses of Fentanyl in Laboring Women
Epidural analgesia is the most effective form of labor pain relief. Low doses of local anesthetic (freezing solutions) in combination with opioids (narcotics) are commonly used as epidural solutions to provide pain relief.
- Trial name
- NCT02004899
- Testing
- Fentanyl
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postpartum Period, Depression
Relationship Between Postpartum Mood Disorders and Delivery Experience
The purpose of this study is to evaluate potential risk factors for developing postpartum depression or posttraumatic stress disorder during the first year postpartum in patients who have no preexisting history of PTSD or PPD.
- Conditions
- Postpartum Period, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NCT03004872
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Michigan
Low Back Pain
Effectiveness of a Short, Intensive and Standardised Spa Therapy for Low Back Pain on Sick Leave Duration
The purpose of this study is to determine whether an intensive 5 days long multidisciplinary program (including spa therapy, exercises and patients'education) is more effective regarding return to work than usual care in subacute…
- Trial name
- ITILO (NCT01648738)
- Testing
- Spa therapy, exercise and educational therapy, Usual care
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstetric Pain
Bupivacaine Verus Pethidine for Post Cesarean Section Pain Relief
The aim of this study is to compare between the effect of wound infiltration with bupivacaine or pethidine for post cesarean section pain relief.
- Trial name
- NCT03652116
- Testing
- Wound infiltration by Bupivacaine, Wound infiltration by Pethidine
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Labor Pain
The Application of Analgesia Nociception Index as an Objective Labor Pain Assessment During Epidural Analgesia
Epidural analgesia is considered an effective and safe method for obstetric pain control. Currently, self-assessment pain scales remain to be the gold standard in labor pain evaluation after the administration of epidural…
- Trial name
- NCT03975816
- Testing
- Analgesia nociception index
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Changhua Christian Hospital
Induction of Labor, Pain, Acute
The Effect of IV PAPAVERINE 80 mg Prior to Catheter Balloon Insertion on Bishop Score and Pain
The cervix consists of connective tissue, smooth muscle, and parasympathetic innervation. Smooth muscle makes up about 15% of the cervix, is mainly found under the internal opening of the neck.
- Conditions
- Induction of Labor, Pain, Acute, Labor Pain, Delivery Delayed
- Trial name
- NCT05759364
- Testing
- IV Papaverine 80 mg
- Where
- Israel
- Volunteers
- 128 people
- Sponsor
- Western Galilee Hospital-Nahariya
Labor Pain, Analgesia
Sacral Spread of Sensory Block After Dural Puncture Epidural Technique Compared With Epidural for Labour Analgesia
Neuraxial labor analgesia is a very widely used technique for labor pain relief with a high efficacy and safety. EA (Epidural analgesia) can guarantee a proper control of pain in 95-100% of cases in the first stage of labor, but…
- Trial name
- NCT05217134
- Testing
- DPEA
- Where
- 2 sites in Italy
- Volunteers
- 108 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS