Clinical trials: Pain, Musculoskeletal
Myofascial Trigger Point Pain
The Effect Of Stretching Exercise on Pectoralis Minor Myofascial Latent Trigger Points
This randomised-controlled trial investigates whether a single intervention of manual pressure release combined with stretching exercise has an effect on muscle length, pain perception threshold, and respiratory function in…
- Trial name
- NCT02699294
- Testing
- Manual pressure release, Contract-relax PNF stretch, Z-stretch
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Chronic Pain, Musculoskeletal Pain
Improving Health for Older Adults With Pain Through Engagement (Open-pilot)
The goal of this project is to conduct an open-pilot (N=30) to evaluate the feasibility, acceptability, and fidelity of a mind-body and activity program (GetActive+) with older adults with chronic pain.
- Trial name
- iHOPE (NCT05782231)
- Testing
- GetActive+
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Massachusetts General Hospital
Temporomandibular Joint Dysfunction Syndrome
Analysis of Clinical Data of Patients With Temporomandibular Joint Disorder
According to our previous research and clinical observation results, the motor function of the oral, maxillofacial and cervical body is closely related to the occlusal contact.
- Trial name
- NCT05780827
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Pain, Disability
Do Benzodiazepines Improve the Outcome of Mechanical Physiotherapy for Lumbar Disk Prolapse
Sixty patients were randomized to receive either placebo or diazepam in addition to mechanical physiotherapy and analgesics for the first 7 days of conservative treatment of clinically and radiologically confirmed lumbar disk…
- Conditions
- Pain, Disability, Paresis
- Trial name
- NCT00533286
- Testing
- benzodiacepine
- Sponsor
- University Hospital Tuebingen
Musculoskeletal Inflammatory
ARTERIAL EMBOLIZATION OF PERSISTENT GENICULATE ARTERIES FOR CHRONIC PAIN MANAGEMENT AFTER TOTAL KNEE-REPLACEMENT ARTHROPLASTY(KNEE EMBOLISATION)
Recent works in interventional radiology have shown interesting results in the treatment of musculoskeletal inflammatory sites by arterial embolization. Supra-selective arterial embolization has been successfully developed by Dr.
- Trial name
- NCT04417686
- Testing
- arterial embolization
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Plantar Fasciitis, Chronic
Comparison of Responsiveness of Different Pain and Disability Measurements in Plantar Fasciitis
The aim of the present study is compare the frequently used pain and disability assessment questionnaires before and after 5 sessions of standard treatment for patients admitted to the Physical Medicine and Rehabilitation…
- Trial name
- NCT04271696
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Musculoskeletal Pain, Breast Cancer
Phase 3 Study Randomized Evaluating the Efficacy of Auriculotherapy in Patients With Musculoskeletal Pain by Aromatase Inhibitors
Auriculotherapy is a complementary medicine, with few side effects, without contraindication, inexpensive and not very restrictive.Its efficacy has been found in several tests especially for the treatment of intraoperative pain.
- Trial name
- TRIPLE-A (NCT03096041)
- Testing
- Auriculotherapy for analgesic use
- Where
- 7 sites in France
- Volunteers
- 197 people
- Sponsor
- Centre Francois Baclesse
Headache, Cognitive Disturbance
Effects of IV-Administered Ca-DTPA and Zn-DTPA To Treat Patients With Gadolinium Deposition Disease
Purpose: There are two goals we have for this prospective single arm study; to see an increase in the amount of gadolinium in 24 hour urine collection following each infusion treatment with Calcium and Zinc DTPA, and to see a…
- Conditions
- Headache, Cognitive Disturbance, Skin Hyperpigmentation, Arthralgia
- Trial name
- NCT02947022
- Testing
- Calcium DTPA, Zinc DTPA
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of North Carolina, Chapel Hill
Temporomandibular Joint Disorder
Effectiveness of Vitamin B in Reducing Temporomandibular Joint Disorder Pain
The purpose of this study is to determine effectiveness of vitamin B in reducing temporomandibular joint disorder (TMD) pain. Patients will be randomised to receive the study drug or placebo.
- Trial name
- NCT02794922
- Testing
- Neurovit Forte, Corn Starch
- Where
- China
- Volunteers
- 27 people
- Sponsor
- The University of Hong Kong
Lateral Epicondylitis, Tennis Elbow
Wrist Heavy Slow Resistance and Shoulder Stabilization Exercises on Pain, Grip Strength and Functional Ability in Lateral Epicondylitis
The study will compare the shoulder and wrist treatment approaches to determine their effect on elbow. Thirty-two medically stable participants with active shoulder and wrist movements will be enrolled into two groups.
- Trial name
- NCT07576829
- Testing
- Wrist heavy slow resistance exercises, Shoulder stabilization exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- University of Faisalabad
Lumbar Disc Herniation, Annular Disc Tear
A Post Marketing Surveillance Study
This study is a prospective, multi-center study to monitor the early safety and performance of one iteration of the Barricaid Anular Closure Device (ACD) - 6mm anchor width, when used as an adjunct to limited discectomy.
- Conditions
- Lumbar Disc Herniation, Annular Disc Tear, Annular Tear of Lumbar Disc
- Trial name
- 6MM (NCT03366779)
- Testing
- 6mm annular closure device
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 20 people
- Sponsor
- Intrinsic Therapeutics
Fibromyalgia
Virtual Reality for Fibromyalgia
Fibromyalgia is a frequent chronic pain syndrome almost often affecting women and associating diffuse chronic musculoskeletal pain (for more than 3 months), fatigue and sleep disturbances.
- Trial name
- VR_Fibro (NCT05567861)
- Where
- Monaco
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Princesse Grace
Muscular TMD
Effect of Different Oral Splints on the Maximum Bite Force in TMD Patients
The goal of this clinical trial is to evaluate whether three different types of intraoral splints can increase maximal voluntary mandibular clenching force in adults diagnosed with myogenous temporomandibular disorders (TMD).
- Trial name
- NCT07016256
- Testing
- intraoral devices
- Where
- Chile
- Volunteers
- 150 people
- Sponsor
- Universidad Vina del Mar
Long COVID, Chronic Pain
Characterization of Long Covid Pain in Primary Care
Justification: among the sequelae of Covid-19 in clinical practice we frequently find persistent neuromusculoskeletal pain. Prevalence data and the underlying mechanisms of such pain are very limited in the scientific literature.
- Conditions
- Long COVID, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT05894642
- Testing
- 0
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Stroke; Sequelae
Postural Decoding for Post-Stroke Shoulder Pain: A RCT.
Brief Summary Purpose of the Study: This clinical trial aims to determine whether Postural Decryption Technique can effectively treat hemiplegic shoulder pain (HSP) in patients recovering from stroke.
- Trial name
- NCT06763796
- Testing
- Postural Decryption Technique, Traditional Chinese Medicine (TCM) Massage Therapy
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Shenzhen Baoan District Fuyong People's Hospital
Arthritis
Fitness and Exercise for People With Arthritis
The purpose of this study is to develop and evaluate a progressive, land-based exercise program, that includes muscular and aerobic conditioning, resistance and stabilization exercises and balance training, for persons with…
- Trial name
- NCT00252070
- Testing
- Functional Exercise for People with Arthritis (FEPA)
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Knee Osteoarthristis
Combination of Platelets Rich Plasma and Hyaluronic is an Effective Tool for Treatment of Knee Osteoarthritis
The purpose of the study is to determine the effects of HA, PRP and the combination of HA and PRP in reducing pain and improving functional disability in patients with knee osteoarthritis.
- Trial name
- NCT07089446
- Testing
- Hyaluronic Acid (HA), Platelet Rich Plasma, Hyaluronic Acid (HA) and Platelet rich plasma
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Karachi
Pain, Osteoarthritis
Impact of Peripheral Nerve Blockade on Outcomes After Total Knee Replacement
Pain is common after knee replacement surgery and can impact a variety of patient outcomes. Peripheral nerve blocks provide improved pain control and may improve function.
- Trial name
- NCT02742961
- Testing
- Peripheral nerve block
- Where
- Canada
- Volunteers
- 178,214 people
- Sponsor
- Ottawa Hospital Research Institute
Stroke Sequelae, Chronic Pain
Transcraneal Magnetic Stimulation for Treatment of Non-nociceptive Pain in Chronic Diseases
Background: Chronic non-nociceptive or nociplastic pain and neurological sequelae following stroke are associated with substantial functional impairment and reduced quality of life.
- Conditions
- Stroke Sequelae, Chronic Pain, Fibromyalgia, Long COVID19
- Trial name
- FATMAGPAIN (NCT07888673)
- Testing
- Transcraneal Magnetic Stimulation (rTMS)
- Where
- 2 sites in Spain
- Volunteers
- 47 people
- Sponsor
- Hospital Donostia
Temporomandibular Joint Dysfunction, TMD
Effects of Core Strengthening Exercises for Treating TMD
Temporomandibular disorders (TMD) are commonly managed with non-invasive interventions such as manual therapy, therapeutic exercise, relaxation techniques, and patient education.
- Conditions
- Temporomandibular Joint Dysfunction, TMD, TMJ Internal Derangement, Myofascial Pain
- Trial name
- NCT07226505
- Testing
- Experimental: Group 1: Core Strengthening, Group 2: Standard TMD PT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loyola University
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