Clinical trials: Pain, Post Surgical
Postoperative Pain
Transversus Abdominis Plane Block Versus Wound Infiltration for Pulmonary Function Preservation Following Laparoscopic Living Donor Nephrectomy
This study compares two pain control techniques in patients undergoing laparoscopic kidney donation surgery: transversus abdominis plane (TAP) block versus wound infiltration with local anesthetic.
- Trial name
- TAPWIN (NCT06837909)
- Testing
- Transversus abdominis plane (TAP) block, Wound infiltration
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
Local Analgesia Via Nerve Block
A Study of Bupivacaine Liposome Injection in the Treatment of Pain After Thoracoscopic Surgery
The objective of this study is to evaluate the efficacy, safety, and tolerability of bupivacaine liposomes for paravertebral nerve block in the treatment of thoracoscopic postoperative pain, and to evaluate the relevant human…
- Trial name
- NCT06529432
- Testing
- Bupivacaine Liposome Injection, Bupivacaine Hydrochloride Injection
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Post Operative Pain
Effect of Preoperative Information About Pain on Postoperative Pain Experience and Patient Satisfaction
Patients are randomized into 2 groups. The intervention group which receives preoperative counseling about pain and a control group which does not receive this counseling.
- Trial name
- epps (NCT03056521)
- Testing
- preoperative information about pain
- Where
- Uganda
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Makerere University
Post Operative Pain
Effectiveness, Safety, and Tolerability Study of Oxymorphone Immediate Release (IR) Oral Liquid in Post Surgical Pediatric Subjects
The purpose of this study is to evaluate the effectiveness, tolerability, and safety of oxymorphone immediate release (IR) oral liquid as an analgesic for acute postoperative pain in pediatric subjects.
- Trial name
- NCT01210352
- Testing
- oxymorphone HCl
- Where
- 8 sites in United States
- Volunteers
- 61 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Head and Neck Cancer, Pain, Musculoskeletal
Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery
The aim of the study is to assess the effects of a continuous popliteal block on postoperative pain and recovery after major ear, nose and throat surgery with microvascular free flap reconstruction using a fibula graft.
- Trial name
- NCT03607227
- Testing
- Levobupivacaine, Saline Solution
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Skane
Pain, Postoperative
Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
This study will compare IV (intravenous) versus oral (PO) acetaminophen for postoperative pain after scheduled, elective Cesarean delivery.
- Trial name
- NCT02487303
- Testing
- Acetaminophen Intravenous, Acetaminophen Oral
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Postoperative Pain
Efficacity, Safety and Cost of Intravenous Morphine Titration Alone or Combined to Ketamine
This is a randomised, controlled, double blinded study comparing in the postoperative setting the analgesic efficacy, the safety and the cost in two groups of patients receiving in the postanesthesia care unit either intravenous…
- Trial name
- KEMO (NCT01146145)
- Testing
- Ketamine
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Arthritis
Perioperative Analgesia for Knee Arthroplasty (PAKA)
Peri-articular knee infiltration with Levobupivicaine 150mg, Morphine 10mg and Ketorolac 30mg reduces postoperative pain following primary total knee replacement compared with the current standard treatment of femoral nerve…
- Trial name
- PAKA (NCT01560767)
- Testing
- Femoral Nerve Block, peri-articular infiltration
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- University of Warwick
Endodontic Disease, Postoperative Pain
Postoperative Pain in Endodontic Therapy
The goal of this clinical trial is to evaluate the change in postoperative pain in mandibular premolar and first molar teeth with asymptomatic apical periodontitis when using EDDY and passive ultrasonic irrigation activation…
- Trial name
- NCT06741592
- Testing
- EDDY Group, PUI Group
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ordu University
Pain, Pain, Postoperative
S-ESP and Ring Block in Circümcision Surgery (S-ESP: Sacral Erectör Spinae Plane Block).
Although it is not known exactly when and where circumcision was first performed, it is claimed that it was first performed by the Egyptians, according to various beliefs and traditions.
- Trial name
- NCT06136000
- Testing
- Sacral erectör spinae plane block, Ring Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Konya City Hospital
Tonsillectomy, Post-Operative Pain
Acupuncture for Post-tonsillectomy Pain Control in Children
A randomized, controlled, single-blinded study comparing conventional postoperative analgesia with paracetamol-on-demand with the same regime plus acupuncture.
- Conditions
- Tonsillectomy, Post-Operative Pain, Acupuncture
- Trial name
- NCT01285687
- Testing
- acupuncture
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Ziv Hospital
Pain, Postoperative
Interscalene Catheter vs. Interscalene Liposomal Bupivacaine for Arthroscopic Rotator Cuff Repair
Arthroscopic rotator cuff repair often causes significant postoperative pain. An interscalene nerve catheter is an effective and proven method to help reduce postoperative pain and decrease opioid use around the time of shoulder…
- Trial name
- NCT04571606
- Testing
- Single injection peripheral nerve block with liposomal bupivacaine (Exparel), Single injection peripheral nerve block with 0.25% bupivacaine and subsequent peripheral nerve catheter with 0.2% bupivacaine infusion via onQ pain pump
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of North Carolina, Chapel Hill
Neuropathy;Peripheral
Depolarising Electrical Skin Stimulation in Neuropathic and Postoperative Pain
The aim of the study is to evaluate voltage gated sodium channel (NaV1.7) dependent pain phenomena in neuropathic pain and chronic postoperative pain.
- Trial name
- NCT03037684
- Testing
- neurophysiology
- Where
- Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Breast Cancer
Chronic Post Breast Surgery Pain
The purpose of this study is to learn if paravertebral block (PVB) will reduce chronic pain after surgery. Our hypothesis is that chronic pain from breast surgery as a consequence of central sensitization can be prevented by…
- Trial name
- NCT00847067
- Testing
- Paravertebral block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Lumbar Disc Herniation
QLB vs ESPB for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle to anesthetize the thoracolumbar nerves.
- Trial name
- NCT06477198
- Testing
- QLB, ESPB, Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Limb Pain, Phantom, Residual Limbs Pain
Pain and Disability Outcomes in Post Amputation Patients
The objective of this study is to evaluate efficacy of varied medical and procedural therapies used to treat pain after surgical amputation of a limb.
- Conditions
- Limb Pain, Phantom, Residual Limbs Pain, Disability Physical
- Trial name
- NCT05716321
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Milton S. Hershey Medical Center
Acute Post Operative Pain
Various Strategies to Reduce Acute Post Hemorrhoidectomy Pain: A Comparative Study
Since post hemorrhoidectomy pain is a severe and common post operative symptom so there is a need to find a suitable method for reducing this pain, up to our knowledge, this the first study in ZUH to compare between ketrolac…
- Trial name
- NCT06307106
- Testing
- ketorolac and light marcaine, light marcaine, Corticosteroids injection
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Zagazig University
Nephrectomy, Laparoscopic Donor Nephrectomy
Intravenous Ketorolac for Postoperative Pain in Laparoscopic Donor Nephrectomy
The purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having laparoscopic surgery to donate a kidney.
- Trial name
- NCT00765232
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Mayo Clinic
Post-operative Dyspareunia
Dilators for Dyspareunia Prevention
This is a randomized clinical trial comparing rates of de novo dyspareunia in women with and without vaginal dilator use following surgery for pelvic organ prolapse with traditional posterior repair.
- Trial name
- DDS (NCT01299363)
- Testing
- Dilator use
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Postoperative Pain After Limb Lengthening, Limb Lengthening
Pain Beliefs and Functional Performance After Cosmetic Limb Lengthening Using the Lengthening Over Nail (LON) Technique
This pilot observational study aims to examine the relationship between pain beliefs, pain intensity, and functional performance in individuals who have undergone cosmetic lower limb lengthening surgery using the Lengthening Over…
- Trial name
- LON-PILOT (NCT07438821)
- Testing
- Postoperative Functional and Pain Assessment
- Volunteers
- 58 people
- Sponsor
- Istanbul Aydın University
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