Clinical trials: Pain, Post Surgical
Pain, Postoperative
Serratus Anterior Plane Block Versus Intercostal Block
Pain after thoracotomy is the most severe pain experienced by the patient. Good pain control after the operation provides comfortable respiration and reduces the development of chronic pain and complications.
- Trial name
- NCT03309267
- Testing
- Intercostal block, Serratus anterior plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Arthroscopic Shoulder Surgery, Pain, Postoperative
Examining the Effectiveness of a Connective Tissue Matrix Implant in Reducing Post-operative Pain and Narcotic After Outpatient Arthroscopic Shoulder Surgery
This document is a protocol for a human research study. This study is to be conducted according to United States standards of Good Clinical Practice in accordance with applicable Federal regulations and institutional research…
- Trial name
- ECM (NCT04633837)
- Testing
- Extracellular Matrix Graft Injectable Implant
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brian Badman
Pain
The Evaluation of Postoperative Pain After Caesarean Section
The aim of this study is to determine the effect of surgical priority either emergency or elective on postoperative pain in caesarean section operations.
- Trial name
- NCT02332395
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Tokat Gaziosmanpasa University
Pain, Postoperative, Cholecystectomy, Laparoscopic
Effects of Preoperative Gabapentin Versus Pregabalin on Shoulder Pain After Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effect of premedication with pregabalin or gabapentin versus placebo on postoperative shoulder pain after laparoscopic cholecystectomy.
- Trial name
- NCT03241875
- Testing
- Pregabalin 75mg, Gabapentin 300mg
- Where
- Tunisia
- Volunteers
- 90 people
- Sponsor
- Faculty of Medicine, Sousse
Pain
A Study to Evaluate the Efficacy and Safety of HR18042 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery.
This is a multicenter, randomized, double-blind, dose finding, parallel controlled with active drug and placebo, phase II clinical trial, and the purpose of the study is to evaluate the efficacy and safety of HR18042 tablets for…
- Trial name
- NCT05470075
- Testing
- HR18042 tablets, Tramadol hydrochloride SR Tablets
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Scoliosis
Sensorial and Physiological Mechanism-based Assessments of Perioperative Pain
The overall goal of this proposal is to determine if quantitative sensory testing (QST) assessing pain modulation can be used as a clinical tool to optimize perioperative pain management.
- Trial name
- RCT (NCT03537612)
- Testing
- Clonidine, Morphine
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Dr. Jean A. Ouellet, MD, FRCSC
Pain, Postoperative, Postoperative Nausea and Vomiting
Effect of Pulmonary Recruitment Maneuver (PRM) on Pain and Nausea After Laparoscopic Bariatric Surgery
The purpose of this prospective, blinded, randomized clinical trial is to investigate whether a ventilator-piloted PRM at the end of laparoscopic bariatric surgery could reduce overall postoperative pain and nausea.
- Trial name
- NCT03026530
- Testing
- Pulmonary recruitment maneuver, Laparoscopic bariatric surgery, Ventilator
- Volunteers
- 200 people
- Sponsor
- Region Östergötland
Hyperhidrosis
Study to Assess the Efficacy of Botulinum Toxin B (Myobloc) for the Treatment of Prosthesis-associated Sweating
The objective of this study is to determine if Myobloc significantly decreases prosthesis-associated symptomatic sweating in amputees when compared to a saline solution placebo.
- Trial name
- NCT01671800
- Testing
- Botulinum Type B
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Pain, Postoperative
Comparison of AI-Generated Pain Scoring Visuals With Visual Analog Scale (VAS) for Pain Assessment
This prospective study will be conducted in surgical wards, assessing postoperative patients. Initially, patients will be evaluated using the VAS method.
- Trial name
- NCT06456853
- Testing
- Pain assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pain, Postoperative
Post-Operative Pain Control in Opioid Tolerant Patients: Fentanyl Challenge Protocol Versus Standard of Care
This study will evaluate the value of dosing pain medications based upon a patient's pre-operative tolerance to pain medications. Study participants will be assigned to one of two groups, a treatment group and a control group.
- Trial name
- NCT02324933
- Testing
- Fentanyl
- Where
- United States
- Sponsor
- Bassett Healthcare
Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma
Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia
The aim of the study is to test the effectiveness and safety of the use of lidocaine infusion in multimodal analgesic management.
- Conditions
- Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma, Surgery, Pain, Postoperative
- Trial name
- NCT04691726
- Testing
- lidocaine 10mg/ml, Metamizole, Morphine
- Where
- Poland
- Volunteers
- 87 people
- Sponsor
- Łukasz Krzych
Pain, Postoperative, Thoracic Diseases
Liposomal Bupivacaine for Pain Control Following Thoracic Surgery.
The aims of the study are to compare the effectiveness and postoperative outcomes of liposomal bupivacaine vs plain bupivacaine following video-assisted thoracoscopic surgery.
- Conditions
- Pain, Postoperative, Thoracic Diseases, Local Anesthetics Causing Adverse Effects in Therapeutic Use, Opioid Dependence
- Trial name
- NCT03036085
- Testing
- Liposomal bupivacaine, Bupivacaine, Epinephrine
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Total Knee Arthroplasty
The Relationship Between Preoperative Serum Cytokine Level and Lenght of Stay in Hospital, Postoperative Pain Intensity, Functional Status, Joint Position Sense and X Ray Findings
Serum cytokines was assosiated with symptoms and progression of osteoartritis. It is unknown whether these cytokines have a predictive role on severity of symptoms after total knee arthroplasty (TKA) or not.
- Trial name
- NCT04487535
- Testing
- Cytokine level
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Hacettepe University
Postoperative Pain, Open Nephrectomy
Modified External Oblique Intercostal Plane Block Versus Erector Spinae Plane Block for Open Nephrectomy
This prospective, randomized, assessor-blinded clinical trial aims to compare the postoperative analgesic efficacy of ultrasound-guided Erector Spinae Plane Block (ESPB) and Modified External Oblique Intercostal Plane Block…
- Trial name
- EOIPB-ON (NCT07726550)
- Testing
- Erector Spinae Plane Block, Modified External Oblique Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Namik Kemal University
Pain
The Effect of an Individualized Education Intervention on Pain Following Inguinal Hernia Repair Surgery
Pain after inguinal hernia repair surgery is common with more than 50% of patients reporting moderate to severe acute pain following surgery.
- Trial name
- HREI (NCT01063790)
- Testing
- Individualized Education
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- University of Toronto
Postoperative Pain After a Total Knee Arthroplasty
Post-operative Analgesic Effect of Oral Nefopam
Primary knee arthroplasty by total prosthesis is a painful surgery, performed on patients with advanced gonarthrosis (stage III), thus already presenting hyperalgesia and hyperalgesia and allodynia.
- Trial name
- NefPO (NCT04576078)
- Testing
- Oral nefopam
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Pain, Postoperative, Opioid Use
Management Of Pain After Cesarean Trial
This is a double blinded randomized controlled trial to test the efficacy of a combination of acetaminophen and ibuprofen administered to patients on schedule compared to ibuprofen alone on the patient's reported pain score on…
- Trial name
- MOPAC (NCT03929640)
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Milton S. Hershey Medical Center
Pain, Postoperative
Celecoxib in Postoperative Analgesia for Radius Fracture Surgery
Patients scheduled for elective osteosynthesis of the distal radius will be randomized to receive celecoxib 100 mg orally (PO) at 6 in the morning before surgery and every 12 hours for 2 days thereafter, or a placebo pill in the…
- Trial name
- NCT05288374
- Testing
- Celecoxib 100 mg
- Where
- 2 sites in Czechia
- Volunteers
- 42 people
- Sponsor
- Charles University, Czech Republic
Neck Disease, Head and Neck Cancer, Neuropathic Pain
"Effect of Low Level Laser Therapy on Neuropathic Pain After Neck Dissection Surgery''
The purpose of the study was to evaluate the effect of Low Level Laser Therapy on neuropathic pain after neck dissection surgery.
- Trial name
- NCT06762574
- Testing
- Low Level Laser Therapy
- Volunteers
- 52 people
- Sponsor
- Cairo University
Postoperative Pain, Pain Management
The Effect of Intravenous Dexketoprofen on the Severity and Incidence of Rebound Pain
Orthopedic shoulder surgeries are associated with severe postoperative pain, particularly within the first 24-48 hours after surgery.
- Conditions
- Postoperative Pain, Pain Management, Rebound Pain, Interscalene Block
- Trial name
- NCT07642674
- Testing
- ISB + paracetamol IV 3*1, ISB+ paracetamol IV 3*1 +deksketoprofen IV 2*1
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Eskisehir Osmangazi University
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