Clinical trials: Pain, Somatic
Low Back Pain, Mechanical, Piriformis Syndrome
Strain-Counterstrain Treatment of Piriformis Pain
The purpose of this investigator-initiated study is to provide an efficient and non-invasive treatment option for pain caused by the piriformis muscle.
- Conditions
- Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
- Trial name
- NCT05023005
- Testing
- Strain-Counterstrain treatment of piriformis muscle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Somatic Pain
Investigation of Low-intensity Focused Ultrasound Pressure
Investigating the relationship between input pressure of low-intensity focused ultrasound and an evoked potential in both eeg and fMRI.
- Trial name
- NCT06343883
- Testing
- low-intensity focused ultrasound - low pressure, low-intensity focused ultrasound - medium pressure, low-intensity focused ultrasound - high pressure
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Neuropathic Pain, Depression
The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Spinal cord Injury (SCI) is a condition commonly associated with a state of chronic low-grade inflammation due to a variety of factors such heightened risk for infection and development of metabolic disorders.
- Conditions
- Neuropathic Pain, Depression, Cognitive Impairment, Somatic Neuropathy
- Trial name
- NCT02099890
- Testing
- Omega-3, Vegetation Protein Powder, InflanNox
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brock University
Neck Pain
The Natural History of Upper Trapezius Myofascial Trigger Points: Comparison of Local and Remote Tissue Milieu in Normal Muscle, Latent and Active Myofascial Trigger Points Over Time
This study will use microdialysis to investigate myofascial pain. This pain is characterized by "trigger points" (exquisitely tender spots) in a group of tense muscle fibers that extend from the trigger point to the muscle…
- Trial name
- NCT00042276
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Placebo, Expectations
Effects of Expectations on Negative Affect, Perceived Cognitive Effort, and Pain
The investigators administer a functional neuroimaging task to investigate the effect of cue expectancy on participants' self-reported ratings across a variety of affective and cognitive domains.
- Trial name
- NCT05425563
- Testing
- Pain Expectancy Cues, Vicarious Pain Expectancy Cues, Cognitive Effort Expectancy Cues
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Joint Pain
Study to Evaluate the Safety and Efficacy of a Proprietary "Joint Health" Dietary Supplement in Subjects With Joint and Connective Tissue Pain
This study is designed to evaluate the effectiveness of a proprietary nutritional supplement that contains Krill Oil (KO), astaxanthin (AX) and hyaluronic acid (HA) to reduce pain and discomfort in participants, compared to an…
- Trial name
- NCT03209895
- Testing
- Joint Health Product, Glucosamine / Chondroitin
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- U.S. Nutraceuticals, LLC
Healthy Volunteer
The Accuracy and Efficacy of AI-driven tVNS Algorithm
Pain, including somatic and visceral pain, is a common symptom. Persistent pain can lead to repetitive visits to hospitals and can limit patients' daily activities, which can result in tremendous medical cost and lower quality of…
- Trial name
- NCT05215756
- Testing
- transcutaneous vagal nerve stimulation
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Back Pain, Back Pain Lower Back
Use of Ultrasound Imaging in Confirming Osteopathic Spinal Diagnosis
In the field of Osteopathic Medicine, diagnosis of potential areas of dysfunction are diagnosed by the physician using their hands and expertise in noticing subtle differences in symmetry, tone, swelling etc..
- Conditions
- Back Pain, Back Pain Lower Back, Back Pain Lower Back Chronic, Back Pain With Radiation
- Trial name
- NCT07858071
- Testing
- Spinal Ultrasound
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Elderly (People Aged 65 or More)
The Effects of Somatic-Based Chair Exercises in the Elderly
The primary aim of this study is to investigate the effects of easily applicable somatic-based chair exercises on balance and pain in the elderly.
- Trial name
- NCT07618143
- Testing
- Somatic-Based Chair Exercises, Conventional Exercise Group
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul Gedik University
Catastrophizing Pain, Pain, Somatic
The Association Between Conditioned Pain Modulation and Pain Catastrophizing in Chronic Low Back Pain
This study evaluates the potential association between pain catastrophizing thoughts and the ability to dampen pain via endogenous descending inhibition.
- Conditions
- Catastrophizing Pain, Pain, Somatic, Chronic Low Back Pain
- Trial name
- NCT03644810
- Testing
- PPT measurement, Pain catastrophizing scale, Cold Pressor Test
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Major Depression, Pain
Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder
Patients with major depressive disorder (MDD) commonly have many gastrointestinal complaints. Gastrointestinal pain is classified into 2 categories: visceral and somatic pain.
- Conditions
- Major Depression, Pain, Abdominal Pain
- Trial name
- NCT00209807
- Testing
- escitalopram, Reboxetine, No intervention
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Pain (Visceral, Somatic, or Neuropathic)
Distolingual Infiltration Verses Conventional Nerve Block in Mandibular Third Molar Extraction
This randomized controlled trial will compare the effectiveness of adding distolingual infiltration to conventional inferior alveolar and buccal nerve blocks for mandibular third molar extraction.
- Trial name
- NCT07296926
- Testing
- Conventional Inferior Alveolar and Buccal Nerve Block, Distolingual Infiltration plus Conventional Nerve Block
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Back Pain, Lumbar Pain
Osteopathic Manipulative Treatment for Back Pain
This study will investigate if Osteopathic Manipulative Treatment (OMT) is beneficial for patients presenting with back pain.
- Conditions
- Back Pain, Lumbar Pain, Thoracic Pain, Somatic Dysfunction
- Trial name
- NCT03892759
- Testing
- Osteopathic Manipulative Therapy
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Pacific Northwest University of Health Sciences
Fear Pain
Human Behaviors Related to the Expectation of Pain
The conditioned expectation of pain is an important aspect of pain-related disability produced by environments and stimuli associated with a painful injury on the job, although the neuroscience of this expectation is unclear.
- Trial name
- NCT03739645
- Testing
- Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tissue Pain
Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness
This study involves imaging the skin movements of surface tissue on the back. A clinician will perform assessment and intervention procedures manually, using manual and light movements of stretch and compression.
- Trial name
- OptMeasSkin (NCT06390085)
- Testing
- Soft tissue manipulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Pain (Visceral, Somatic, or Neuropathic)
Postoperative Pain and Swelling After Flap vsFlapless Technique For Mandibular Third Molar Surgery
This randomized controlled trial evaluates postoperative pain and facial swelling following surgical removal of partially impacted mandibular third molars using flap versus flapless techniques.
- Trial name
- NCT07247929
- Testing
- flap technqiue for mandibular third molar extraction Arm A, flapless technquie arm b
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College