Clinical trials: Pain Intervention
Pain Control, Liver Cancer
Hepatic Hilar Nerve Block Versus Sham in Pain Control During Liver Ablation and TACE Procedures
This study is aimed at assessing the effectiveness of a novel liver specific nerve block in improving pain control during painful liver interventional radiology procedures including liver tumoral ablation and trans arterial…
- Trial name
- NCT04769713
- Testing
- Hepatic Hilar Nerve Block Needle placement, Injection of Ropivacaine in the hepatic hilum for the hepatic hilar nerve block
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Pain
The Effectiveness of Information and Relaxation on Pre-procedural Block Anxiety and Procedural Discomfort During Medial Branch Block
Patient presenting to chronic pain clinics frequently undergo diagnostic and therapeutic spinal injections as part of their treatment.
- Trial name
- TIRAP (NCT00901082)
- Testing
- Relaxation and information session
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Louise Lamb
Neck Pain, Neck Disability
This Study Explores How Short-term Immersive VR With Exercises and Ergonomic Training Can Reduce Neck Pain, Improve Movement, Strength, and Work Productivity in Computer Users Who Are at High Risk Due to Prolonged Screen Time and Poor Posture.
The goal of this clinical trial is to learn if a short-term immersive Virtual Reality (VR) intervention, combined with exercises and ergonomic training, can help treat neck pain in computer users.
- Conditions
- Neck Pain, Neck Disability, Neck Endurance, Work Productivity
- Trial name
- VR ROM (NCT06962982)
- Testing
- Therapeutic Exercises, Ergonomic Training, Human XR device - Oculus Quest 3
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Gulf Medical University
Anxiety, Pain
Colposcopy Anxiety and the Role of Pre-procedure Nursing Intervention
Colposcopy is essential for the diagnosis and prevention of cervical cancer. However, receiving screening results and being informed of the need to undergo a colposcopic examination are significant sources of anxiety for…
- Trial name
- NCT07092189
- Testing
- Pre-colposcopy counseling by a clinical nurse, Treatment as usual: regular call to schedule the appointment without pre-procedure conseilling
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Université de Sherbrooke
Back Pain Lower Back Chronic, Disability Physical
Project AdaPT: An Adaptive Physiotherapy Intervention Augmented With a Healthy Mind Training Program for People With Chronic Low Back Pain
In the proposed research, we will elucidate the comparative effectiveness of standalone physiotherapy (PT) vs. PT augmented with a self-guided, app-based Healthy Minds Innovation wellbeing program (PT+HMI) aimed at cultivating…
- Trial name
- AdaPT (NCT06351774)
- Testing
- Physical therapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Ohio University
Post-Concussion Syndrome, Post-Traumatic Headache
Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology
The purpose of this study is to compare a 4-week, moderately intensive, lab and home-based aerobic exercise program versus exercise plus cognitive training.
- Conditions
- Post-Concussion Syndrome, Post-Traumatic Headache, Post-Concussive Syndrome, Chronic, Head Injury
- Trial name
- NCT03674398
- Testing
- Exercise+CT, Exercise only
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Paracervical Block
Paracervical Block During Office Hysteroscopy
The purpose of this study is to determine the effectiveness of paracervical block for pain relief in office hysteroscopy - particularly with the placement of the Essure device.
- Trial name
- NCT00811187
- Testing
- Lidocaine paracervical block, Normal Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Infant, Pain
Effect of Three Different Sensory Interventions on Pain Level During Heel Blood Collection in Term Infant
Background: Healthy newborns undergo many painful procedures in the first hours of life. Damage caused by painful procedures can lead to structural and functional changes that can affect adult life.
- Trial name
- NCT05526378
- Testing
- Sensory Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Heart Disease
CTCA Prior to Invasive Angiography in Post-Bypass Patients (BYPASS CTCA 2)
The goal of this clinical trial is to evaluate whether a coronary computed tomography angiography (CTCA)-guided strategy can reduce the risk of death, heart attack, stroke, and hospital admissions in patients experiencing angina…
- Trial name
- NCT07165678
- Testing
- CTCA
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Queen Mary University of London
Low Back Pain (LBP), Chronic Low Back Pain
Lumbar Support Belt for Low-Back Pain in Office Workers
Background: Low-back pain (LBP) is common among office workers and can reduce productivity and quality of life. Lumbar support belts are commonly used to manage LBP, but their effectiveness specifically for office workers remains…
- Conditions
- Low Back Pain (LBP), Chronic Low Back Pain, Non-specific Low Back Pain
- Trial name
- NCT07030816
- Testing
- Guardner Belt
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- General Incorporated Foundation Ryukyuseimeisaiseikai, Ryusei Hospital.
Anterior Knee Pain Syndrome
Efffectiveness of a Roller Intervention in Anterior Knee Pain
Anterior knee pain is one of the most frequent reasons for consultation within knee conditions in adolescents and young adults. However, despite the high prevalence of this disorder, its pathogenesis and therefore its treatment…
- Trial name
- NCT03620799
- Testing
- Manual therapy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Oncologic Surgery, Cancer
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery.
- Conditions
- Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer
- Trial name
- LapTAP (NCT06731998)
- Testing
- Local Anesthesia, Laparoscopic Transversus Abdominis Plane block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Gulf War, Fatigue
Groups for Regaining Our Wellbeing
This study is a randomized clinical trial measuring outcomes up to 6-months post-intervention. The objective of this study is to evaluate outcomes of two different group interventions for Veterans with Chronic Multisymptom…
- Conditions
- Gulf War, Fatigue, Pain, Depression
- Trial name
- GROW (NCT03058952)
- Testing
- Mindfulness-Based Stress Reduction, Chronic Disease Self-Management Program
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- VA Office of Research and Development
Endodontically Treated Teeth
Postoperative Pain After İntracanal Procedures
Aim: The aim of this study is to investigate the effects of different irrigation activation systems on pain after endodontic treatment in molar teeth with irreversible pulpitis.Post-operative pain values of the participants will…
- Trial name
- NCT04892355
- Testing
- Root canal irrigation
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Surgical Procedures, Operative, Pain
Characterization of Post-operative Pain Trajectories Over Seven Days and Links With Chronicity
The main objective of this study is to establish the postoperative "pain pathways" observed from D1 to D7 in the context of the current management after orthopedic, digestive, obstetrics and gynecology, urology, neurosurgery…
- Conditions
- Surgical Procedures, Operative, Pain, Chronic Pain
- Trial name
- PATCH (NCT02599233)
- Testing
- Telephone conctact at 3 months, In hospital pain evaluation, In hospital questionnaires
- Where
- France
- Volunteers
- 392 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Low Back Pain, Exercise
Effect of an Intervention Based on Back School in an Aquatic Environment on Non-specific Low Back Pain
A controlled and randomized clinical trial will be conducted, in which scores on dependent variable measures will be compared before and after the intervention, both in the experimental group (EG) (individuals who will attend the…
- Conditions
- Low Back Pain, Exercise, Healthy
- Trial name
- NCT06437314
- Testing
- Aquatic program based on the back school
- Where
- Spain
- Sponsor
- University of Vigo
Dexamethasone Adverse Reaction, Postoperative Pain
Role of Dexamethasone in Multimodal Analgesia for Postoperative Pain in Thoracic Surgery
The aim of the study is to evaluate the analgesic properties of dexamethasone and to quantify the possible associated postoperative complications, such as wound infections and hyperglycaemia, in patients who underwent lobectomy…
- Conditions
- Dexamethasone Adverse Reaction, Postoperative Pain, Postoperative Thoracic Procedure Complication, Analgesia
- Trial name
- NCT04325984
- Testing
- Dexamethasone
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- University of Trieste
Hemodynamics, Pain
Hemodynamic Effects of Different Vasoconstrictors in Mandibular Exodontia
Title of Study: The Effect of Different Vasoconstrictive Agents on Hemodynamics Among Patients Undergoing Simple Mandibular Exodontia: A Triple-Blind Randomized Controlled Trial Location: King Abdulaziz University Dental Hospital…
- Conditions
- Hemodynamics, Pain, ASA I-II Requiring Simple Dental Extraction of a Mandibular Tooth
- Trial name
- NCT07013071
- Testing
- 2% Mepivacaine with 1:100,000 epinephrine, 2% Mepivacaine with 1:55,000 Epinephrine Bitartrate
- Where
- Saudi Arabia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Pulp Diseases, Dental Pulp Necrosis
Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material
Non-surgical root canal therapy (RCT) represents a standard of treatment that addresses infected pulp tissue in teeth and protects against future infection while preserving the tooth for the patient for mainly cosmetic purposes.
- Conditions
- Dental Pulp Diseases, Dental Pulp Necrosis, Nerve Root Pain Nec
- Trial name
- NCT02698163
- Testing
- Nanodiamond reinforced Gutta Percha, Gutta Percha
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, Los Angeles
Low Back Pain
Effectiveness of the SelfBack-App in Preventing and Treating Low Back Pain Versus no Intervention: a Non-randomized Clinical Trial
Low back pain (LBP) is the leading cause of disability worldwide and represents a major burden for both individuals and healthcare systems.
- Trial name
- NCT07785804
- Testing
- Selfback app, No Interventions
- Where
- Belgium
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel