Clinical trials: Pain Management
Needlestick Injuries
The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic
The aim of the study is to find a simple method for pain reduction that can be used in clinical practice when administering digital nerve block with a single subcutaneous injection.
- Trial name
- NCT02086292
- Testing
- 2 ml 1% Lidocaine, 1 ml 2% Lidocaine
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Chronic Pain Syndrome, Sensitization, Central
Management of Chronic Non-Cancer Pain With Non-Pharmacological Therapies
A randomized controlled clinical trial will be conducted, involving a psychoeducational activity as the intervention. There will be a control group of patients with non-cancer chronic pain who will continue their usual treatment.
- Conditions
- Chronic Pain Syndrome, Sensitization, Central, Quality of Life, Patient Empowerment
- Trial name
- NCT06440668
- Testing
- Chronic Pain Management Workshop with Non-Pharmacological Therapies
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla
Lumbar Puncture, Topical Analgesia
Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in Children
The purpose of this study is to evaluate the effectiveness of a needle-free jet-injection system with 1% buffered lidocaine for local anesthesia for lumbar punctures compared to a topical anesthetic agent.
- Trial name
- JTIP (NCT01628874)
- Testing
- J-Tip, EMLA, Lidocaine
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Osteoarthritis, Rheumatoid Arthritis
Web-based Support to Manage Arthritis Pain
Development of an interactive, online pain self-management program for adults who suffer from pain associated with osteoarthritis, rheumatoid arthritis, Ankylosing spondylitis, and other arthritic conditions (e.g., psoriatic…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Other Arthritic Conditions (e.g., Psoriatic Arthritis)
- Trial name
- NCT01463189
- Testing
- painACTION: Arthritis
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Inflexxion, Inc.
Breast Cancer, Postoperative Pain
Serratus Plane Block vs Erector Spinae Plane Block on Postoperative Analgesia in Patients Undergoing Unilateral Breast Surgery
Interfacial plan blocks are becoming more widely used for postoperative analgesia because of their easier applicability and less risk of complications.
- Trial name
- NCT04218149
- Testing
- Bupivacaine Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Sickle Cell Disease, Pain
Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
- Conditions
- Sickle Cell Disease, Pain, Acupuncture, Quantitative Sensory Testing
- Trial name
- NCT06725550
- Testing
- needling acupuncture, laser acupuncture
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Labouring Parturients Requiring/Requesting Epidural Analgesia as Part of Their Peri-partum Care
A Comparison Study Of Two Different Techniques For Identifying The Epidural Space In Parturients In Labour
The purpose of this study is to determine whether the use of the Epidrum device to identify the epidural space in labouring parturients reduces morbidity, when compared to standard loss of resistance techniques.
- Trial name
- NCT01574391
- Testing
- Epidrum
- Where
- Ireland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Maternity Hospital, Ireland
Pain Management, 3D Printing
The Effectiveness of the Three-dimensional Biochemical Activity Model of Pain
Aim: In this study, it was aimed to develop a pain biochemical activity model taken from a three-dimensional printer and fixed by applying epoxy resin and to investigate the effect of this model on nursing students' understanding…
- Conditions
- Pain Management, 3D Printing, Education Nursing
- Trial name
- NCT07389382
- Testing
- 3D printed pain biochemical activity training model, PowerPoint Presentations
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Pain
Impact of Naloxone on the Analgesic Effect of Paracetamol in Healthy Volunteers
The aim of this study is to check if Naloxone induce an inhibiting effect on the analgesic effect of paracetamol in healthy volunteer, using evoked potentials.
- Trial name
- NCT00750048
- Testing
- Naloxone and paracetamol
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Gout, Acute Gout Flare
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral ABP-745 Administration in Healthy Volunteers
A randomized, double-blind, placebo-controlled, dose-escalation study will be conducted in healthy volunteers. This study will evaluate the safety, tolerability, and pharmacokinetics (PK) of ABP-745 following single (Part 1) and…
- Conditions
- Gout, Acute Gout Flare, Gout Flares
- Trial name
- ABP-745 (NCT06258213)
- Testing
- ABP-745
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Atom Therapeutics Co., Ltd
Low Back Pain
Clinical Trial to Evaluate the Food Effect on the Pharmacokinetics of Eperisone HCl SR Tablet 75mg
The purpose of this study is to evaluate the food effect on the pharmacokinetics of eperisone HCl SR tablet
- Trial name
- eperisone (NCT01885520)
- Testing
- fasting condition, fed condition
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- NVP Healthcare
Postoperative Pain
The Analgesic Efficacy of Wound Infiltration With Tramadol
This double-blind, randomized trial examined whether tramadol wound infiltration decreased postoperative pain following cesarean delivery under general anesthesia or reduced the need for analgesics in the immediate postoperative…
- Trial name
- NCT02518438
- Testing
- Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeditepe University Hospital
Uterine Evacuation
The Impact of Doulas in Early Pregnancy Management
The purpose of the study is to examine the impact of doula support for women undergoing a manual vacuum aspiration (MVA) for an early pregnancy failure or undesired pregnancy.
- Trial name
- NCT02165540
- Testing
- Doula
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Depression, Postpartum
The Correlation Between Prelabor Analgesic Plan and Actual Labor Analgesia With Satisfaction, Postpartum Depression, and Breast Feeding Success
In this study the investigators would like to evaluate how prelabor analgesic plan and actual labor analgesia effects the labor satisfaction, breastfeeding success, and whether or not it reduces postpartum depression.
- Trial name
- NCT02495350
- Testing
- Questionarie
- Where
- Israel
- Volunteers
- 1,954 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Laparoscopic Cholecystectomy
Dexamethasone-Enhanced TAP Block in Lapchole
The transversus abdominis plane (TAP) block is widely used as part of analgesia for abdominal surgeries such as laparoscopic cholecystectomy. While bupivacaine is commonly used for TAP blocks with reported success.
- Trial name
- NCT07182110
- Testing
- Dexamethasone enhanced TAP Block, Marcaine- 0.25%
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Breast Cancer
Modified Pectoral Nerve Block Versus Serratus Plane Block
In PECSII or modified PECSI block, local anesthetic (LA) is injected between pectoralis major muscle (PMm) and pectoralis minor muscle (Pmm) to block lateral and medial pectoral nerves and between pectoralis minor muscle (Pmm)…
- Trial name
- NCT04895397
- Testing
- ultrasound guided Nerve Block procedure
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Osteoarthritis
Patient Controlled Epidural Analgesia Versus Local Infiltration Analgesia Following Knee Arthroplasty
The purpose of this study was to determine if the method of peri-operative analgesia used following total Knee Replacement surgery affected the progress towards rehabilitation goals and to determine whether the analgesia had any…
- Trial name
- NCT02478372
- Testing
- Patient Controlled Epidural (PCEA), Local Infiltration Analgesia (LIA)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Golden Jubilee National Hospital
Pain
Omnitram Pharmacokinetic and Analgesic Study Following CY2D6 Inhibition With Paroxetine In Healthy Volunteers
This study evaluates the analgesic effect of Omnitram and tramadol during concurrent administration of paroxetine. Paroxetine administration is expected to diminish the analgesic effect of tramadol, but not Omnitram.
- Trial name
- NCT03312777
- Testing
- Omnitram, Tramadol
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syntrix Biosystems, Inc.
Healthy
Evaluation of Pain Reduction in the Administration of Saline Injections by the Usage of Pneumatic Skin Flattening
Each participant will be administered 2 injections of saline - the first in the right gluteal area and the second in the left gluteal area. Both injections will be administered intra-muscularly by the same clinician.
- Trial name
- NCT00503087
- Testing
- Saline Injection, Pneumatic Skin Flattening (PSF)
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- PalJect Ltd.
Analgesia
Efficacy and Safety of Lidocaine and Tetracaine Cream for Facial Laser Aesthetics in Chinese Adults
Lattice laser is a new medical cosmetic technology, which is a kind of noninvasive and invasive technology. Compared with traditional laser therapy, lattice laser has a wider range of clinical use, and can be used to treat skin…
- Trial name
- NCT05793892
- Testing
- Lidocaine tetracaine cream
- Where
- 11 sites in China
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Cutia Therapeutics（Wuxi）Co.,Ltd
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