Clinical trials: Pain Management and Care
Pain
Exparel for Pain Control During Care of Rib Fractures
This study is looking at a novel therapy of numbing medication injected directly around the fracture site. The purpose of this study is to determine if the study medication, EXPAREL®, is a viable alternative to current therapies…
- Trial name
- NCT02390440
- Testing
- EXPAREL
- Where
- United States
- Sponsor
- Michael Moncure, MD
Mechanical Ventilation, Analgesia
Improving Adherence to the Sedation-analgesia Protocol in Pediatric Intensive Care
Sedation-analgesia is a major concern in the management of children in pediatric intensive care units (PICUs). International guidelines recommend the use of sedation-analgesia protocols, as their implementation has already proven…
- Conditions
- Mechanical Ventilation, Analgesia, Nurse Training
- Trial name
- SEDATIDE2 (NCT07038850)
- Testing
- Multimodal nurse training about nurse driven sedation-analgesia protocol
- Where
- 2 sites in France
- Volunteers
- 285 people
- Sponsor
- Hospices Civils de Lyon
Head and Neck Cancer (H&Amp;Amp;N), Radiation-induced Oral Mucositis
Mouthwash Temperature and Oral Mucositis in Head and Neck Radiotherapy
This single-center randomized controlled trial evaluates the effects of cold (15-20°C) versus room-temperature (30-35°C) water gargling on oral mucositis severity, pain, and comfort in patients with head and neck cancer…
- Conditions
- Head and Neck Cancer (H&Amp;Amp;N), Radiation-induced Oral Mucositis, Supportive Care, Nursing Interventions
- Trial name
- CoolRinseHNC (NCT07252557)
- Testing
- Water Rinse at Different Temperatures
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chung Shan Medical University
Chronic Cancer Pain, Pain Management
Effectiveness of Pain Management Interventions in Patients With Chronic Cancer Pain
The goal of this observational study is to observe the effectiveness of pain management strategies in patients with chronic cancer pain presenting to pain management clinic at Aga Khan University.
- Trial name
- NCT07395999
- Testing
- Pharmacological and pain Intervention procedure
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- Aga Khan University
Colorectal Neoplasms
Acupuncture to Reduce Symptoms of Advanced Colorectal Cancer
This study investigates the effect of acupuncture in reducing symptom distress in adults with advanced colon cancer.
- Trial name
- NCT00034034
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Cancer Pain
Development of a Cloud-Based PRO (Patient-Reported Outcome) Management Program for Home-Based Cancer Pain Care
This study aims to develop and pilot a cloud-based Patient-Reported Outcomes (PROs) management program for home-based cancer pain patients within a hospital setting.
- Trial name
- NCT07308223
- Testing
- Proactive monitoring and patient education
- Where
- China
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Osteoarthritis
Self-Management of Osteoarthritis
The purpose of this study is to examine whether a telephone-based self-management intervention improves pain, physical function, and other outcomes among veterans with osteoarthritis of the hip or knee.
- Trial name
- SeMOA (NCT00288912)
- Testing
- Health Education, Osteoarthritis Self-Management
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Persistent Post-surgical Pain, Neuropathic Pain
Development of a Personalised Care Plan Designed to Reduce Chronic Post-Operative Pain Following Breast Surgery
Numerous surveys have shown that following breast surgery, longterm pain affects around half of patients. Given that 1 in 9 women will get breast cancer and that surgery is the cornerstone of treatment, persistent pain represents…
- Conditions
- Persistent Post-surgical Pain, Neuropathic Pain, Cancer Pain
- Trial name
- NCT02170415
- Testing
- Protective analgesia, Pain education, Psychological support
- Where
- United Kingdom
- Volunteers
- 154 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Analgesic Drugs, Analgesic, Nonopioid
Continuous vs. Bolus Administration of NSAIDs After Laparoscopic Surgery for Multimodal Analgesia
Currently the prevalent approach to perioperative management of patients is ERAS (Enhanced Recovery After Surgery) concept. This approach includes numerous aspects, among which the perioperative use of multimodal analgesia takes…
- Conditions
- Analgesic Drugs, Analgesic, Nonopioid, Analgesic Efficacy, Analgetic Consumption
- Trial name
- NCT07070050
- Testing
- Ibuprofen continuous infusion, Ibuprofen bolus injection
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology
Chronic Pain, Palliative Care
Pain and Symptom Management in Rural Communities
Patients in isolated rural settings often lack easy access to pain care and specialist services. Yet rural residents are more likely than their urban counterparts to be older; be in poorer overall health; suffer from more chronic…
- Trial name
- TelePain (NCT02070874)
- Testing
- telehealth enhanced pain management
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- University of Washington
Intensive Care Unit
Regional Anaesthesia in Intensive Care Unit
Pain is a major problem in Intensive Care Unit (ICU). Adequate pain management not only means decreasing the pain intensity, but also improving the functionality and allowing the early mobilization that is a prerequisite for…
- Trial name
- Week'ALR (NCT05131633)
- Where
- 19 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain Management, Ergonomics
COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP)
Home care workers (HCWs) are at-risk for chronic pain and associated problems, including emotional distress, opioid use and misuse, and work-related disability.
- Conditions
- Pain Management, Ergonomics, Wounds and Injuries
- Trial name
- COMPASS-NP (NCT05492903)
- Testing
- COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chronic Pain
Medication Review Improves Pain Management and Quality of Life in Chronic Pain
The goal of this parallel-group, single-blinded, randomized study is to conduct Medication Review (MR) Type III in chronic non-cancer pain patients to optimize drug therapy and measure it's influence on Pain Intensity and Quality…
- Trial name
- NCT06997861
- Testing
- Medication Review Type III, Usual Care
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Polytechnic Institute of Porto
Acute Pain Due to Trauma
Methoxyflurane vs Standard Analgesic Treatment for Trauma Pain in Spanish Emergency Units
Clinical trial to compare pain relief between methoxyflurane and any analgesic treatment used in usual clinical practice, in patients with trauma and associated pain, treated in Spanish emergency units.
- Trial name
- InMEDIATE (NCT03256903)
- Testing
- Methoxyflurane, Standard of care
- Where
- 14 sites in Spain
- Volunteers
- 310 people
- Sponsor
- Mundipharma Pharmaceuticals S.L.
Chronic Non-malignant Pain
Pain Program for Active Coping & Training
The overall aim of this study is to adopt an integrative rehabilitation approach for helping patients adopt self-management skills for managing chronic pain, limiting use of opioid medications, and identifying exacerbating…
- Trial name
- PPACT-UH2 (NCT01888146)
- Testing
- Interdisciplinary pain program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kaiser Permanente
A Study on the Effect of Animation-based Nurse-Patient Interaction Model on Postoperative Pain in Children With Congenital Heart Disease
Application of Nurse-Patient Interaction Model Based on Animated Cartoons in Postoperative Analgesia for Preschool Children With Congenital Heart Disease.
I. Research Objective To verify the efficacy of an animated nurse-patient interaction model in alleviating postoperative pain in children with congenital heart disease, optimize non-pharmacological analgesic nursing processes for…
- Trial name
- CCU (NCT07319260)
- Testing
- Routine care
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Beijing Children's Hospital
Pain
The ACTIVE Intervention to Improve Hospice Care
The ACTIVE Intervention to Improve Hospice Caregiver Pain Management The major goal of this project is to implement and test this promising intervention in three hospice programs.
- Trial name
- NCT01211340
- Testing
- ACTIVE
- Where
- 2 sites in United States
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Burn
Virtual Reality Pain Control During Burn Wound Care
Using Virtual Reality as a form of Distraction during Burn Care.
- Trial name
- VRPT/H2O/RT (NCT00261690)
- Testing
- Virtual Reality Distraction
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Pain, Opioid Tolerance
Effect of N-methyl D-aspartate (NMDA) Receptor Antagonist Dextromethorphan on Opiods Analgesia and Tolerance in Pediatric Intensive Care Unit Patients
Effect of N-methyl D-aspartate (NMDA) receptor antagonist Dextromethorphan on Opiods analgesia and tolerance in Pediatric Intensive Care Unit Patients
- Conditions
- Pain, Opioid Tolerance, Analgesia Tolerance
- Trial name
- NCT01553435
- Testing
- Dextromethorphan
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Abdullah International Medical Research Center
Pelvic Pain, Distress, Emotional
Pelvic Pain Education and Skills Training for Women Veterans
The goals of this pilot randomized clinical trial are three-fold: 1) to test the feasibility of conducting a larger randomized trial using a brief Acceptance and Commitment Training (ACT) group intervention for women veterans…
- Trial name
- NCT06062043
- Testing
- Brief ACT with CPP Education Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine