Clinical trials: Pain Monitoring
Pain Monitor During Anesthesia
Observational Evaluation of the Last Version of the PMD200TM
Title: Evaluation of the last version of the PMD200TM and its NoL index in patients undergoing laparotomies with intraoperative epidural analgesia Objectives: Measure NoL Index changes after a standardized nociceptive electrical…
- Trial name
- NCT02884778
- Testing
- Detection of pain after nociceptive stimulus
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
The Characteristics of Different Personal Lancets on Blood Volume and Perceived Pain in Patients With Diabetes Mellitus
A randomized single-blind study with the use of different lancing devices equipped with personal lancets to determine and to compare the amount of capillary blood volume and perceived pain after a single lancing of the fingertip.
- Trial name
- NCT04253431
- Testing
- Droplet lancing device (HTL-Strefa S.A.), Microlet 2 lancing device (Bayer), OneTouch Delicia lancing device (LifeScan)
- Volunteers
- 60 people
- Sponsor
- HTL-Strefa S.A.
Failed Back Surgery Syndrome, Spinal Cord Stimulation
Impact of the SCS With Different Waveforms Over the Quality of Life (SCS-Quality)
Prospective, randomized, multicentre, parallel, controlled, and double-blind trial. It is a study with 2 groups with evaluation pre and post treatment with Spinal Cord Stimulation (SCS) implantation of patients with Failed Back…
- Trial name
- SCS-Quality (NCT04244669)
- Testing
- IPG with Conventional Stimulation, IPG with SCS DTM
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Pablo López Pais
End of Life, Pain
Assessment of the Interest of ANI in the Non-communicating Patient in Palliative Care
Comfort evaluation is one of the major challenges in the palliative care setting, particularly when it comes to non-communicative patients.
- Conditions
- End of Life, Pain, Analgesia
- Trial name
- ANI-CARE (NCT05454202)
- Testing
- ANI
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Lille
Pain Measurement
Intraoperative Nociception Monitoring with Medstorm, Medasense and Anspec-pro During Total Intravenous Anesthesia
The randomized controlled trial study aims to validate a new pain monitor during general anesthesia by comparing the new ANSPEC-PRO monitor (non-CE marked) with already CE-marked pain monitors (Medstorm and Medasense).
- Trial name
- NCT04986163
- Testing
- Non-invasive analgesia monitoring with ANSPEC-PRO monitor and MEDSTORM monitor, Non-invasive analgesia monitoring with ANSPEC-PRO monitor and MEDASENSE monitor, Non-invasive analgesia monitoring with MEDSTORM monitor and MEDASENSE monitor
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- University Hospital, Ghent
Anesthesia
Comparison of Different Analgesia-Monitors in Tracing Unconscious Pain Sensations
Until today there is no standard-monitoring to specifically reflect the analgesic component of general anesthesia. Quality and safety of general anesthesia are of major clinical importance and can be improved by limiting the…
- Trial name
- AMUPS (NCT02429960)
- Testing
- Analgesia monitor (PhysioDoloris®), Analgesia monitor (SPI®), Analgesia monitor (AlgiScan®)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Musculoskeletal Pain
The Effect of Clinical Monitoring Software on Symptoms in Patients With Chronic Low Back Pain
The aim of this randomised controlled trial is to compare the effectiveness of two different telerehabilitation assessment methods in patients with chronic low back pain.
- Trial name
- NCT05816824
- Testing
- Symptom monitoring software via visual feedback
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Muğla Sıtkı Koçman University
Analgesia
Nociception Level During Opioid-sparing Anaesthesia Versus Conventional Opioid-based Anaesthesia
The aim of this double blind, randomised controlled non-inferiority trial is to compare the antinociceptive efficiency of an opioid-sparing and a conventional opioid-based anaesthesia protocol with the help of the CEcertificated…
- Trial name
- NOL_Basel (NCT05485480)
- Testing
- conventional opioid-based group, opioid-sparing group
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University Hospital, Basel, Switzerland
Labor Pain
Continuous Remote Vital Sign Monitoring During Labour Analgesia With Remifentanil
Continuous remote vital sign monitoring during labour analgesia with remifentanil - a prospective observational study Remifentanil PCA represents a well-tolerated, effective and valuable option for labour analgesia, yet its wider…
- Trial name
- NCT07167498
- Testing
- Intermittent midwife absence during remote monitoring of remifentanil PCA in labour
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Nociceptive Pain, Pain, Postoperative
Guiding Opioid Administration by Nociception Level Index (NOL) in Patients With Regional Anesthesia
General anesthesia consists of a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception.
- Conditions
- Nociceptive Pain, Pain, Postoperative, Analgesia, Postoperative, Anesthesia Recovery Period
- Trial name
- NORA (NCT06905340)
- Testing
- NOL (Nociception Level Index), Control (Standard treatment)
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pain, Nausea
Quality of Recovery After Day Care Surgery With App Controlled Remote Monitoring: a Randomized Controlled Trial
Non blinded randomized controlled trial with mixed methods design. To assess the experienced quality of recovery after day care surgery between patients provided with remote home monitoring and patients receiving standard…
- Conditions
- Pain, Nausea, Vomiting
- Trial name
- QuReMo (NCT05244772)
- Testing
- Remote monitoring
- Where
- 3 sites in Netherlands
- Volunteers
- 310 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Surgery, Pain
Clinical Validation of Medasense Pain Response Index (PRI)
In our previous study, NCT01631695, we proposed and clinically evaluated the Medasense pain response index, PRI, in anesthetized patients undergoing surgery. Note: the name PRI has been changed to NoL (Nociception Level) Index.
- Trial name
- NCT01762332
- Testing
- Base level of remifentanil effect side concentration: 2ng/ml, Base level of remifentanil effect side concentration: 4ng/ml, chronic beta-blocker treatment
- Where
- Israel
- Volunteers
- 82 people
- Sponsor
- Medasense Biometrics Ltd
Nociceptive Pain
Nociception and BIS Level Monitoring in COVID-19 Patients in the Intensive Care Unit
Pain (nociception), stress and discomfort are difficult to detect in sedated and intubated patients during mechanical ventilation.
- Trial name
- NEMO (NCT05579106)
- Testing
- Nociception Level Monitor (NOL) by Medasense Biometrics Ltd., Israel, Bispectral index (BIS), Questionnaire perception of the nurse on pain patient
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Leiden University Medical Center
Pain, Chronic, Lumbar Radiculopathy
Study on the Use of Intraoperative Neurophysiological Monitoring in Spinal Cord Stimulator Trials
This is an observational pilot study. The spinal cord stimulator (SCS) procedure and neuromonitoring device is not under investigation. Neuromonitoring is typically performed on this patient population receiving SCS trials here.
- Conditions
- Pain, Chronic, Lumbar Radiculopathy, SCS
- Trial name
- SCS-Monitor (NCT05540756)
- Where
- United States
- Sponsor
- University of Chicago
Pain, Chronic Pain
Negating Opioid and Pain Actively Through Intervention
Chronic pain is one of the most prevalent and debilitating medical conditions and opioid analgesics are a commonly prescribed class of medications in the United States.
- Conditions
- Pain, Chronic Pain, Opioid Use
- Trial name
- NOPAIN (NCT03306147)
- Testing
- Pain education with follow up encounters
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Knee Osteoarthritis
Clinic-based and Tele-monitored Home-based Intervention in Patients With Knee OA
This study assessed and compared the effects of clinic-based and telemonitored home-based interventions on pain intensity, function and quality of life in patients with knee osteoarthritis (KOA).
- Trial name
- CB&HMInKOA (NCT05832866)
- Testing
- Clinical Based Isometric contraction strengthening Exercises using Thera band, Telemonitored Home based Isometric Cntraction strengthening exercises using Thera band
- Where
- Nigeria
- Volunteers
- 42 people
- Sponsor
- Obafemi Awolowo University
Cardiac Arrythmias, Unstable Angina
CardioSenseSystem Compared Study Regarding Efficacy and Safety in the Monitoring of ECG
This is a prospective, controlled, comparative clinical trial of a new ECG monitoring system CardioSenseSystem prior CE marking.
- Conditions
- Cardiac Arrythmias, Unstable Angina, Heart Valve Disorders, Disorder of Aorta
- Trial name
- NCT03610529
- Testing
- CardioSenseSystem, Philips Intellivue
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Novosense AB
Spinal Disease, Anesthesia
Influence of Lidocaine Infusion on Motor Evoked Potential Thresholds
The purpose of this study is to determine the effect of lidocaine infusion on intraoperative neuromonitoring in patients undergoing spine surgery.
- Conditions
- Spinal Disease, Anesthesia, Post Operative Pain
- Trial name
- NCT06792474
- Testing
- Lidocaine in Saline, Normal saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Acute Pain, Analgesics
Monitoring Side Effects Of Pain Medication Prescribing By Emergency Department In Patients Over 65
Half of the people over the age of 65 are not functioning at their optimal level because of interference from pain. > 50% of older adults had taken prescriptions of pain medication beyond a 6-month period.
- Conditions
- Acute Pain, Analgesics, Elderly
- Trial name
- MOSE65 (NCT02046681)
- Where
- 5 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Pain, Acute
Lidocaine Before Esophageal Manometry and Ambulatory pH Monitoring
A randomized controlled trial comparing esophageal manometry and ambulatory pH monitoring test tolerance in the presence versus in the absence of topical lidocaine.
- Trial name
- NCT03967197
- Testing
- Saline spray, Lidocaine Hydrochloride
- Where
- Canada
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)