Clinical trials: Pain Perception
Birth Outcomes, Labor Pain and to Reduce Pain
The Effect of the Intrapartum Care Model Given in Line With WHO Recommendations on the Birth Process and Care
This study aimed to evaluate the effects of the intrapartum care model provided in line with the World Health Organization (WHO) recommendations on labor pain, fear, comfort, duration, oxytocin use and perception of midwifery…
- Conditions
- Birth Outcomes, Labor Pain and to Reduce Pain, Fear of Birth, Birth Comfort
- Trial name
- NCT06681675
- Testing
- The group that applied the Intrapartum Care Model
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Acupressure, Intensive Care Unit
Effects of Acupressure Applied to Intensive Care Patients on Physiological Parameters, Pain, Sleep Quality, Anxiety and Perception of Nursing Presence
This study will be conducted in a randomized controlled experimental design to examine the effects of acupressure applied to patients treated in the intensive care unit on physiological parameters, pain, sleep quality, anxiety…
- Conditions
- Acupressure, Intensive Care Unit, Anxiety, Nursing Presence
- Trial name
- NCT06994715
- Testing
- Acupressure, pseudo acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
Pain, Regulation, Self
Multisensory Integration and Pain Perception
Pain is a predominant disruption of well-being among humans. Feeling pain is a multimodal sensory experience where information is collected and processed from various senses such as sight and touch.
- Trial name
- NCT03471689
- Testing
- Mindfulness meditation, Positive reappraisal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Spinal Cord Injuries, Neuropathic Pain
Brain Activity Patterns in Persons With Spinal Cord Injury and Neuropathic Pain After a Virtual Walking Training Program
The aim of this pilot study is to explore the association of changes in pain perception with changes in brain activity (functional Magnetic Resonance Imaging (fMRI)) and metabolic (Magnetic Resonance Spectroscopy (MRS)) patterns…
- Trial name
- VRandMRI (NCT05098587)
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Mild Cognitive Impairment, Chronic Inflammation
The Grounded Brain: How Sleeping Grounded Affects Memory and Perceptions
Grounding (Earthing) refers to the practice of contacting the Earth or a properly installed grounding mat with the body. Previous studies on grounding have shown positive effects body-wide inflammation, acute and chronic pain…
- Trial name
- NCT05050812
- Testing
- grounding mat
- Volunteers
- 8 people
- Sponsor
- California Institute of Integral Studies
Chronic Low-back Pain (cLBP)
Visual Feedback Manipulation in Virtual Reality Alters Extension-evoked Pain Perception in Chronic LBP
This study investigates the potential to modify movement-evoked pain in individuals with chronic low back pain (LBP) by manipulating visual proprioceptive feedback through virtual reality (VR).
- Trial name
- CLEVER BODY (NCT06750900)
- Testing
- NORMAL CONDITION, UNDERSTATED CONDITION, OVERSTATED CONDITION
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cardenal Herrera University
Bone Marrow Aspiration, Pain
Visual and Auditory Distraction for the Relief of Pain and Anxiety
Bone marrow (BM) examinations are performed in diagnostic workup of malignancies, in particular hematological diseases, and are frequently associated with significant pain, distress, and anxiety.
- Conditions
- Bone Marrow Aspiration, Pain, Anxiety, Hematologic Diseases
- Trial name
- NCT07023692
- Testing
- Distraction with VR (Virtual Reality) headsets
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Region Skane
Chronic Pain, Chronic Low Back Pain
Effects of tDCS and TUS on the Perception of Pain and Functional Limitations Due to Non-Specific Chronic Low Back Pain
The purpose of this study is to assess the effects of tDCS in combination with TUS for the treatment of pain and functional limitations in subjects with NSCLBP.
- Trial name
- NCT02954432
- Testing
- transcranial Direct Current Stimulation (tDCS), Transcranial Ultrasound (TUS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Spaulding Rehabilitation Hospital
Pain
Pain Therapy After Elective Cardiac Surgery
The purpose of this study is to determine generation of a target controlled infusion model for the patient controlled analgesia with the strong analgesic, hydromorphone, after planned open heart surgery, during which the strong…
- Trial name
- PKPDHM-001 (NCT01490268)
- Testing
- Sufentanil, Hydromorphone
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Local Anesthetic Complication
Comparative Effect of Palatal Injection in Pediatric Patient
The aim of this study is to compare the pain perception of pediatric patients during extraction with and without palatal injection and to show whether articaine HCl and lidocaine HCl can provide palatal anesthesia in maxillary…
- Trial name
- NCT06025825
- Testing
- Articaine Hydrochloride + Epinephrine, Lidocaine Hydrochloride + Epinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara Yildirim Beyazıt University
Pain
Sedation and Pain (The Effect of IV Sedation on Pain Perception)
The investigators propose to evaluate the potential effect of sedation on pain perception in two ways, by asking for a participant's pain rating(subjective) and by evaluating a subject's brain activation using fMRI(objective).
- Trial name
- NCT00853333
- Testing
- dexmedetomidine, midazolam, propofol
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Migraine, Fibromyalgia
Aerobic Training Effect on the Improvement of Pain Perception in Patients With Fibromyalgia and Migraine
Fibromyalgia and migraine are diseases with high prevalence in women between the age group of 30-60 years, which seem to share the same pathophysiological mechanism; both originate from neuroendocrine disorders of the…
- Trial name
- NCT02458326
- Testing
- Aerobic training, Control Training
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Endometriosis, Chronic Pelvic Pain Syndrome
Effect of Massage and Hydrotherapy to Improve Well-being and Pain Perception in Endometriosis Patients
The objective is to analyze the short-term effect of a comprehensive HAMMAM experience combining therapeutic hydrotherapy, aromatherapy, music therapy, and Swedish massage on objective parameters and patient-reported outcomes…
- Trial name
- NCT06506708
- Testing
- Hydrotherapy + massage
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad de Granada
Diabetes Mellitus, Type 2, Neuropathic Pain
Effect of a Combined Exercise Program on Neuropathic Pain and Perceived Quality of Life in Type 2 Diabetes
Therapeutic exercise is one of the therapies used as a treatment for diabetic neuropathy, which is a complication of diabetes. In order to reduce pain and improve the perception of quality of life, a combined therapeutic exercise…
- Conditions
- Diabetes Mellitus, Type 2, Neuropathic Pain, Neuropathy, Diabetic
- Trial name
- NCT05703152
- Testing
- Combined Exercise
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Maria Gabriela Aké Palomo
Chronic Pain
The Role of Sensory Processing Sensitivity in Pediatric Chronic Pain
The aim of this project is to increase scientific understanding of whether the trait of SPS can help explain increased pain sensitivity and hence vulnerability for chronic pain.
- Trial name
- NCT04473014
- Testing
- Heat Pain Paradigm
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Approximal Dental Caries (ICDAS 3-5) in Primary Molars of Children
A Randomized Clinical Trial Comparing Hall vs. Conventional Technique in Primary Molars.
This study aims to assess the comparative effectiveness of the Hall technique (HT) and the conventional technique (CT) for placing Stainless Steel Crowns (SSCs) in primary molars with approximal caries.
- Trial name
- NCT06350578
- Testing
- Hall Crown Technique, Conventional SSC Technique
- Where
- Qatar
- Volunteers
- 80 people
- Sponsor
- Primary Health Care Corporation, Qatar
Pain Management, Anxiety
Effects of EFT on Postpartum Safety Perception, Anxiety, and Postoperative Pain After Cesarean Section
This study is a parallel randomized controlled trial on 60 primiparous women with cesarean section pain, randomly divided into EFT and control groups.
- Trial name
- NCT06999564
- Testing
- EFT
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Healthy
Objective Markers of Pain Perception in Humans
Determine objective markers of pain perception remains a major scientific and medical issue. Various tools have been proposed to objectify pain, but their adaptability to different clinical contexts are limited.
- Trial name
- NCT02559999
- Testing
- Painful tonic stimuli, non-painful stimuli
- Where
- 2 sites in France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Chronic Pain, Fibromyalgia
Full-Spectrum Cannabis Extract for Chronic Pain and Bone Health Biomarkers in Women
Chronic pain disproportionately affects women and may coexist with impaired bone health, particularly during midlife and after menopause.
- Conditions
- Chronic Pain, Fibromyalgia, Osteoporosis, Orofacial Pain
- Trial name
- ORION (NCT07783295)
- Testing
- Full-Spectrum Cannabis Extract 5:1 (CBD:THC)
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Associação Pan-Americana Multidisciplinar de Endocanabinologia