Clinical trials: Pain Perception, active
Bilateral Arthritis of Wrist, Tendinopathy
Vibratory Anesthesia on Pain Following Corticosteroid Injections
This research study aims to evaluate injectional pain at the site of needle insertion for corticosteroid injections (CSI) of the upper extremity depending on different modes of anesthetics.
- Conditions
- Bilateral Arthritis of Wrist, Tendinopathy, Arthropathy, Compression Neuropathy
- Trial name
- NCT07553273
- Testing
- Digivibe Device
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Root Resorption, Pain Perception
AI-Designed Clear Aligners: A Randomized Clinical Trial
The goal of this clinical trial is to evaluate the clinical performance and validity of applying AI-based TruRoot-designed clear aligners in adult orthodontic patients.
- Conditions
- Root Resorption, Pain Perception, Treatment Duration
- Trial name
- NCT06968325
- Testing
- AI-based TruRoot group:, Conventional clear aligner group
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- University of Baghdad
Vulvodynia, Naltrexone
Effectiveness of Low-dose Naltrexone in Patients With Different Types of Vulvodynia
Vulvodynia (Vd) is chronic functional vulvar pain, with prevalence of 3-16% and unclear etiopathology. Although Vd significantly deteriorates quality of life, the problem is marginalized, no pharmacologic treatment standards…
- Conditions
- Vulvodynia, Naltrexone, Quality of Life
- Trial name
- NCT05955313
- Testing
- Naltrexone Hydrochloride
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Lublin
MSK Conditions
Feasibility and Acceptability of an Evidence-Informed Virtual Intervention to Reduce Perceptions of Injustice Following Work Injury
Many individuals who have sustained disabling injuries in the workplace react to their situation with a sense of 'injustice'. Research over the past 20 years has revealed that, interpreting one's post-injury life situation as…
- Trial name
- NCT07072702
- Testing
- Managing Post-Injury Challenges (MPIC)
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- McGill University
Bone Marrow Aspiration, Pain
Visual and Auditory Distraction for the Relief of Pain and Anxiety
Bone marrow (BM) examinations are performed in diagnostic workup of malignancies, in particular hematological diseases, and are frequently associated with significant pain, distress, and anxiety.
- Conditions
- Bone Marrow Aspiration, Pain, Anxiety, Hematologic Diseases
- Trial name
- NCT07023692
- Testing
- Distraction with VR (Virtual Reality) headsets
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Region Skane
Cystoscopic Surgical Procedures, Pain
Physicians' Perception About Patient Pain in Flexible Cystoscopy With Local Anesthesia
Cystoscopy with local anesthesia is commonly performed for the follow-up of bladder cancer, evaluation of hematuria, assessment of urethral strictures, and examination of the lower urinary tract.
- Trial name
- NCT06944314
- Testing
- Diagnostic procedures, Flexible Cystoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Dental Caries in Primary Molars
Clinical Comparison of Cariclast Gel and Rotary Drilling Technique for Caries Removal in 2d Primary Molars
This randomized clinical trial aims to compare two different methods of caries removal in primary molars: the chemomechanical technique using Cariclast gel and the conventional rotary drilling method.
- Trial name
- CARICLAST-RCT (NCT07270458)
- Testing
- cares removal using cariclast gel, Conventional Mechanical Caries Removal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Prostate Cancer (Diagnosis), Prostate-Specific Antigen
Intraprostatic Anesthesia During Transperineal Prostate Biopsy
Transperineal prostate biopsy has become the standard method for diagnosing prostate cancer because of its favorable safety profile and low infectious complication rates.
- Trial name
- PRO-PAIN (NCT07683182)
- Testing
- Prilocaine, Bupivacaine, Perineal Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Marmara University
Psoriasis Arthritis
Potential Role of Guselkumab in Modulating PAIN Perception and Related Gene Pathways: a Proof-of-concept Study.
Psoriatic arthritis (PsA) is a chronic musculoskeletal disease that affects 0.1%-1% of the general population and about 20% of patients with psoriasis.
- Trial name
- GUPAIN (NCT06974474)
- Testing
- Guselkumab
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Malocclusion of Anterior Teeth
Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled Study
This clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) in conjunction with oral vitamin D3 supplementation in accelerating orthodontic tooth movement in adults with crowded mandibular anterior teeth…
- Trial name
- LLLT (NCT07286474)
- Testing
- Cholecalciferol (Vit D3), Low-Level Laser Therapy, Fixed Orthodontic Appliance
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Osteoarthritis (OA) of the Knee, Fear of Needles
Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?
This study aims to investigate factors that affect the subjective experience of pain during and after intra-articular knee joint injection of steroids by comparing needle gauge size (22 G vs 25 G needles), as well as the presence…
- Trial name
- NCT06865170
- Testing
- 25 gauge needle, 22 gauge needle, +/- Ethyl Chloride Topical Aerosol Anesthetic
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Dental Anxiety, Dental Pain
Effect of Play Dough, Slime, and Plush Toys on Dental Anxiety and Pain in Children During Dental Treatment
This study aims to evaluate the effectiveness of tactile distraction materials, including play dough, slime, and plush toys, on dental anxiety, pain perception, and physiological stress responses in children undergoing dental…
- Conditions
- Dental Anxiety, Dental Pain, Behavioral Management
- Trial name
- PLAY-DENT (NCT07445594)
- Testing
- Play Dough Distraction, Slime Distraction, Plush Toy Distraction
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Colonoscopy, Screening Colonscopy
What Influence Re-participation in the Danish Colorectal Screening Program.
This prospective observational study investigates how participants experience screening colonoscopy within the Danish colorectal cancer screening program and how these experiences relate to clinical findings, procedural factors…
- Conditions
- Colonoscopy, Screening Colonscopy, Pain
- Trial name
- NCT07353632
- Where
- 8 sites in Denmark
- Volunteers
- 8,000 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Musculoskeletal Pain
Effect of Reformer Exercises on Pain Perception in Chronic Musculoskeletal Pain.
This study was planned to investigate whether reformer pilates exercises, which are recommended for the development and maintenance of well-being in musculoskeletal problems associated with low back, neck and back pain, change…
- Trial name
- NCT06706037
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atılım University
Pain, Post Operative, Quality of Life
Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft
The goal of this randomized clinical trial is to compare patient-reported pain and oral health-related quality of life during the first postoperative week following extraction and bone graft surgery in patients who received…
- Trial name
- NCT05919745
- Testing
- Ibuprofen 600 mg, Acetaminophen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marquette University
Pain Management
EFFECT OF BUZZY BEE TO REDUCE PAIN PERECEPTION DURING INFERIOR ALVEOLAR NERVE BLOCK IN CHILDREN - A CROSS OVER STUDY
Pain management during invasive dental procedures is crucial to avoid noncompliance and treatment avoidance. Thus, measures to reduce injection discomfort are needed to prevent patients from avoiding dental treatment.
- Trial name
- NCT07324915
- Testing
- BUZZY BEE [ Vibrating device], Conventional technique
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Jazan
Malocclusions
Effects of Vitamin D in Patients Undergoing Fixed Orthodontic Mechanotherapy
The goal of this interventional research is to determine the impact of vitamin D intake on substances in saliva, pain, tooth movement, and the density of the bone around teeth in patients during orthodontic treatment.
- Trial name
- NCT07299552
- Testing
- Vitamin D (Calcitriol)
- Where
- Malaysia
- Volunteers
- 48 people
- Sponsor
- Hospital Universiti Sains Malaysia
Scoliosis
Investigation of Pain Perception According to Gender in Individuals With Scoliosis
The aim of this study is to evaluate whether pain perception under spinal pressure created on a physiotherapy roller differs according to gender in individuals diagnosed with scoliosis.
- Trial name
- NCT07447193
- Testing
- exercise
- Where
- Azerbaijan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Menstrual Cycle, Menstrual Distress (Dysmenorrhea)
Menstrual Cycle Symptoms and Female Health
The complexity inherent to the hormonal fluctuations associated with the female menstrual cycle (MC) has contributed, from a methodological perspective in research, to the neglect of women's physiological characteristics and to…
- Conditions
- Menstrual Cycle, Menstrual Distress (Dysmenorrhea), Premenstrual Syndrome, Abnormal Uterine Bleeding (AUB)
- Trial name
- CICLOS (NCT07699224)
- Testing
- Prevalence
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Universidad Rey Juan Carlos
Chronic Pain, Chronic Low Back Pain
Effects of tDCS and TUS on the Perception of Pain and Functional Limitations Due to Non-Specific Chronic Low Back Pain
The purpose of this study is to assess the effects of tDCS in combination with TUS for the treatment of pain and functional limitations in subjects with NSCLBP.
- Trial name
- NCT02954432
- Testing
- transcranial Direct Current Stimulation (tDCS), Transcranial Ultrasound (TUS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Spaulding Rehabilitation Hospital