Clinical trials: Pain Reduction
Procedural Pain
Crochet Octopus in The Process of Heel Lance in Neonates
The main objective of the study was to determine the effect of using crochet octopus in order to reduce the acute pain developed during the process of heel lance in neonates.
- Trial name
- NCT04560374
- Testing
- crochet octopus
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Fear and Anxiety
Assessing the Efficacy of Lemongrass and Lavender Aromatherapy in Reducing Dental Anxiety and Pain Associated With Local Anesthetic Injections in Pediatric Dental Patients
The goal of this clinical trial is to evaluate whether aromatherapy using lemongrass or lavender essential oils can reduce dental anxiety and pain perception in children aged 7-11 years undergoing local anesthetic administration…
- Trial name
- NCT07113080
- Testing
- lavender essential oil inhaled using face mask, lemongrass essential oil inhaled using face mask
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hiba Ahmed Eltayeb
Pain
Efficacy of Ametop Cream in Reducing Pain of Local Anesthetic Infiltration
Ametop is a numbing cream used to ease the pain of having blood drawn or an IV inserted. It is safe and virtually none enters the blood stream.
- Trial name
- Ametop (NCT01864213)
- Testing
- Ametop cream
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Efficacy of Dextromethorphan, Morphine Consumption
Efficacy of Pre- and Post-Operative Oral Dextromethorphan
We studied the effect of dextromethorphan (DEX), an N-methyl-d-aspartate antagonist, on analgesic consumption and pain scoring after abdominal hysterectomy.
- Conditions
- Efficacy of Dextromethorphan, Morphine Consumption, Pain
- Trial name
- NCT00199303
- Testing
- pre-operatively followed by 30 mg three times per day after surgery
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Endometriosis, Endometriosis-related Pain
The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery
The purpose of this study is to determine a difference in participant reported pain after endometriosis surgery in participants given oral metronidazole versus placebo.
- Trial name
- NCT04554693
- Testing
- Metronidazole Oral
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Acute Blood Loss Anemia, Postoperative Pain
Effect of Non-Dissection of the Inferior Rectus Sheath on Intraoperative Blood Loss
The purpose of this study is to evaluate the effect of non-dissecting the inferior rectus sheath during primary cesarean delivery on post-operative hemoglobin and post-operative pain control as measured by VAS score and opioid…
- Conditions
- Acute Blood Loss Anemia, Postoperative Pain, Pregnancy
- Trial name
- NCT02762773
- Testing
- non-dissection of inferior rectus sheath, control
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pain, Procedural, Pain Management
The Effect of Two Method to Reducing Pain and Fear During Draw Blood From Children
This study was conducted to evaluate the effects of two different distraction methods on reducing pain and fear during blood collection from children. The study was conducted between January 2020 and May 2021.
- Conditions
- Pain, Procedural, Pain Management, Child, Only
- Trial name
- NCT05064657
- Testing
- Bubble blowing method
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Tooth Bleaching Pain
The Effect of an Experimental Gel Based on Copaiba Oil Resin in Reducing Post-bleaching Tooth Sensitivity
This randomized, double-blind clinical trial aimed to evaluate the effect of an experimental gel containing copaiba oil resin in reducing postoperative tooth sensitivity caused by bleaching with 35% hydrogen peroxide.
- Trial name
- NCT06066671
- Testing
- GCO (Experimental copaiba oil resin gel)
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Postoperative Pain
3D Instrumentation Versus Rotary Instrumentation
enrollment of the patient after diagnosis, radiographic evaluation, and signing the informed consent. allocation of the patient to either intervention or control group.
- Trial name
- NCT03285334
- Testing
- XP-endo Shaper, iRace files
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Injury Leg, Back Pain
Assessment of Effectiveness of Neuromuscular Training in Treatment of Lumbar Spine in Football Players
The project aims to assess the effectiveness of neuromuscular training according to the concept of Kinetic Control (KC) in prevention and treatment of lumbar spine and knee pain and in reduction of risk of injury in female…
- Conditions
- Injury Leg, Back Pain, Sport Injury, Training Group, Sensitivity
- Trial name
- NCT04134741
- Testing
- Kinetic Control
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- John Paul II University in Biała Podlaska
Labor Pain
Effects of Massage With Peppermint Oil on Labor Pain
Birth is a very special experience for a woman and her family. Labor pain is one of the strongest known and defined pains today.
- Trial name
- NCT05136066
- Testing
- massage with peppermint oil
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Local Anaesthesia
Buzzy System Compared to Topical Anaesthesia During Infiltration Injection in Children.
Aim of the study is to test the effect of Buzzy System (vibrating device) compared to topical anaesthesia on pain reduction during injection of infiltration anaesthesia in children.
- Trial name
- NCT05083975
- Testing
- Buzzy System, Topical anesthetic, 1.8 ml of 4% articaine hydrochloride with epinephrine 1:100,000
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
Plantar Fasciitis, Chronic
Intense Therapeutic Ultrasound for the Treatment of Chronic Plantar Fasciitis
A clinical trial evaluating the effectiveness, safety and patient tolerance for the use of Intense Therapeutic Ultrasound (ITU) for chronic, Plantar Fasciitis musculoskeletal tissue pain reduction began in August 2016 and was…
- Trial name
- ITU (NCT03254602)
- Testing
- Intense Therapeutic Ultrasound Treatment
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Foot and Ankle Foundation
Idiopathic Intracranial Hypertension
Idiopathic Intracranial Hypertension Treatment Trial
Idiopathic intracranial hypertension (IIH), also called pseudotumor cerebri, is a disorder of elevated intracranial pressure of unknown cause [Corbett, et al., 1982; Wall, et al., 1991].
- Trial name
- IIHTT (NCT01003639)
- Testing
- Acetazolamide, Formal weight loss counselling program
- Where
- 41 sites in United States, Canada
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Diabetic Neuropathic Pain, Renal Impairment
A Study to Learn How the Study Treatment BAY2395840 Moves Into, Through and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Moderate Reduced Kidney Function and in Healthy Male and Female Participants With Normal Kidney Function
Researchers are looking for a better way to treat people who have inflammatory conditions. Inflammatory conditions may result from an increased activation of the body's natural defenses (the immune system) and are characterized…
- Conditions
- Diabetic Neuropathic Pain, Renal Impairment, Healthy Volunteers
- Trial name
- NCT05406219
- Testing
- BAY2395840
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bayer
Arthroscopic Shoulder Surgery, Pain, Postoperative
Examining the Effectiveness of a Connective Tissue Matrix Implant in Reducing Post-operative Pain and Narcotic After Outpatient Arthroscopic Shoulder Surgery
This document is a protocol for a human research study. This study is to be conducted according to United States standards of Good Clinical Practice in accordance with applicable Federal regulations and institutional research…
- Trial name
- ECM (NCT04633837)
- Testing
- Extracellular Matrix Graft Injectable Implant
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brian Badman
Vaccination
To Look or Not to Look at the Needle During Vaccination
It is common for people to advise individuals undergoing vaccination to look away from the needle to make them hurt less and be less scary. However, this advice is not backed up by research evidence.
- Trial name
- NCT02937428
- Testing
- Look away from the needle, Look at the needle
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cryotherapy
Effect of Cryotherapy on Post-endodontic Pain
The goal of this clinical trial is to compare Cryotherapy with occlusal reduction in the reduction of post-endodontic pain in molars with symptomatic apical periodontitis.
- Trial name
- NCT05722704
- Testing
- Cryotherapy, Occlusal reduction
- Where
- United Arab Emirates
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Stroke, Hemiplegia
Use of Tendon Vibration and Mirror for the Improvement of Upper Limb Function and Pain Reduction
Upper limb paralysis following stroke is a very common problem. Only 30% of stroke patients who suffer from upper limb paresis experience a full recovery of function.
- Trial name
- VibMirror (NCT01010607)
- Testing
- Vibration and Mirror, Mirror therapy
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Effect of Drugs
The Effect of Melatonin on Postoperative Pain Reduction After Orthognathic Surgery
Orthognathic surgery is a procedure performed to correct dentofacial deformities. It involves osteotomy at the facial skeleton. Considerable pain is expected in the early recovery period.
- Trial name
- NCT03995004
- Testing
- Melatonin, Dexamethasone Sodium Sulphate 4mg/1mL
- Where
- Hong Kong
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong