Clinical trials: Pain Scores
Pain
Effect of Gabapentin Enacarbil on Opioid Consumption and Pain Scores
Opioids are effective analgesics, but cause side effects including sedation, respiratory depression, low blood pressure, nausea, and constipation.
- Trial name
- NCT02840240
- Testing
- Gabapentin enacarbil
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- The Cleveland Clinic
Analgesia, Pain, Postoperative
Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery
The rationale for multimodal analgesia is to achieve additive or synergistic analgesic properties while decreasing the incidence of side effects by reducing the dose of each agent.
- Conditions
- Analgesia, Pain, Postoperative, Spinal Stenosis, Spinal Disease
- Trial name
- NCT04391855
- Testing
- Tramadol with ropivacaine, Dexmedetomidine with ropivacaine, Magnesium with ropivacaine
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- Aristotle University Of Thessaloniki
Colonoscopy, Colorectal Cancer Screening
Water Exchange Colonoscopy in Elderly Patients
Colonoscopy is an important test for detecting colorectal polyps and cancer, but it can cause pain and discomfort, especially in older adults. Traditional colonoscopy uses air to expand the colon.
- Trial name
- NCT07830823
- Testing
- Water exchange colonoscopy, Gas insufflation colonoscopy, Propofol and opioid anesthesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First People's Hospital Of Lin'an District, Hangzhou
Post-craniotomy Pain Management, Post-craniotomy
Comparison of Pain Using CPOT Score With Ketamine vs. Dexmedetomidine in Post-Craniotomy ICU Patients
Study Overview: This study is designed to compare two different medications used to manage pain after craniotomy surgery in the ICU.
- Conditions
- Post-craniotomy Pain Management, Post-craniotomy, Pain Control in ICU, Ketamine vs Dexmedetomidine for Pain Relief
- Trial name
- CPOT-KD (NCT07254936)
- Testing
- ketamine, Dexmedetomidine
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Sumatera Utara
Pain
Effect of Lidocaine Spray for Pain Relief During Endometrial Biopsy: a Randomized, Double-blind, Placebo-controlled Clinical Trial
The effect of lidocaine spray on pain relief during endometrial sampling.
- Trial name
- NCT02039661
- Testing
- Lidocaine Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kayseri Education and Research Hospital
Pain During Hysteroscopy
Comparison of Sublingual Misoprostol Versus Lidocaine Spray for Hysteroscopy
Hysteroscopy is an instrument to visualize the interior walls of uterus (womb) and it enables the doctor to do minor operative procedures. Although it causes little discomfort, sometimes it may be disturbing for the patient.
- Trial name
- NCT01718314
- Testing
- Sublingual Misoprostol, Lidocaine pump spray
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Dr. Sami Ulus Children's Hospital
Nonviable Pregnancy
The Effect of Topical Lidocaine on Pain Scores During Manual Vacuum Aspiration for Nonviable Pregnancies
When a patient requires a manual vacuum aspiration (MVA), whether for an undesired pregnancy, missed abortion, or other nonviable pregnancy, she is undergoing an emotional experience.
- Trial name
- NCT01708330
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Bridgeport Hospital
Pain
Influence of Epidural Analgesia in Elective Laparoscopic Colorectal Resections
Epidural anaesthesia in open surgery is a effective method for analgesia and has a positive effect on postoperative resolution of ileus. In laparoscopic surgery, the role of epidural surgery is not established.
- Trial name
- NCT00512395
- Testing
- epidural analgesia (Duracain/Fentanyl/Naropin)
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Pain, Depressive Symptoms
The Effect of Auricular Press Needle on Visual Analogue Scale (VAS) and Short Form (SF-12) Scores in Chronic Pain With Depression Symptoms
Chronic pain is a medical and social problem that can significantly impact the quality of life. Chronic pain is an important risk factor in the development of depression.
- Trial name
- NCT06401031
- Testing
- Press Needle
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Resting Visual Analog Scale (VAS) Pain Score
Liposomal Bupivacaine vs Ropivacaine for Post-hemorrhoidectomy Analgesia
This is a single-center, prospective, randomized, double-blind controlled trial comparing the analgesic efficacy, quality of recovery, and safety of perianal wound infiltration with multivesicular liposomal bupivacaine (266 mg)…
- Trial name
- NCT07795203
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine, Ropivacaine Hydrochloride
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Tongliao City People's Hospital
Partial Meniscal Loss, Lateral Meniscus Partial Loss
Partial Meniscal Replacement with Spongioflex®
The purpose of this investigator-initiated trial is to evaluate whether the novel graft can prevent/reduce the disadvantages of the previously used replacement materials and shows better results than the group of patients, which…
- Conditions
- Partial Meniscal Loss, Lateral Meniscus Partial Loss, Medial Meniscal Partial Loss, Meniscus Lesion
- Trial name
- NCT06775197
- Testing
- partial meniscal replacement with Spongioflex®
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Maria-Josef-Hospital Greven
Diabetic Peripheral Neuropathic Pain (DPN)
NDS and NSS for Screening Diabetic Neuropathy
Diabetic sensorimotor polyneuropathy is a common complication of diabetes mellitus that can lead to pain, sensory loss, foot ulcers, and disability.
- Trial name
- NCT07557641
- Where
- Thailand
- Volunteers
- 228 people
- Sponsor
- Chulalongkorn University
Awakeness, Pain
Relation Between PRST Score, Skin Conductance and BIS
Determine the relation between PRST (pressure, rate, sweating, tears) score, skin conductance (SC) and Bispectral index (BIS) values during anesthesia
- Trial name
- RB (NCT03650283)
- Testing
- monitoring
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Opioid Use, Surgical Recovery
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
The goal of the study to see if giving a numbing medicine around the cervix (called a paracervical block) during vaginal hysterectomy with prolapse repair helps people feel less pain and need fewer strong pain medicines…
- Conditions
- Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic
- Trial name
- NCT07213635
- Testing
- Bupivacaine-epinephrine, Normal saline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Acute Coronary Syndrome
Medical Telephone Triage of Emergency Calls for Thoracic Pain
Thoracic pain is the main symptom of acute coronary syndrome (ACS), urgent and serious illness. Whereas hospital mortality decreased until reaching 10%, out-of-hospital mortality remains high: half of the deaths occur during the…
- Trial name
- DOREMI2 (NCT02042209)
- Where
- 3 sites in France
- Volunteers
- 4,205 people
- Sponsor
- University Hospital, Toulouse
Regional Anesthesia, Pain
Nociception Index Level (NOL) Perioperative Monitoring During Regional Anesthesia
This prospective observational study was conducted to assess pain using NOL index under locoregional anesthesia for orthopedic surgery of the upper limb.
- Conditions
- Regional Anesthesia, Pain, Intraoperative Monitoring
- Trial name
- NOL and LRA (NCT06300606)
- Testing
- NOL monitoring
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- American Hospital of Paris
Rheumatoid Arthritis, Crystal-induced Arthritides
Cryotherapy and Doppler in Inflammatory Rheumatic Diseases
The primary aim of the study is to evaluate the effects of two local cryotherapy (ice or cold gas) applications on arthritic knees.
- Conditions
- Rheumatoid Arthritis, Crystal-induced Arthritides, Spondyloarthritis
- Trial name
- CDRI (NCT02573298)
- Testing
- ice, cold gas
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pain, Postoperative
Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores
This is a multiple center, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of brivoligide injection administered intrathecally before surgery in patients with high Pain Catastrophizing Scale…
- Trial name
- NCT04104919
- Testing
- Brivoligide Injection 660 mg/6 mL
- Sponsor
- Adynxx, Inc.
Osteoarthritis
To Compare Anterior Knee Pain Between Non Severe and Severe Patellofemoral Arthritis After Oxford UKA
The aims of this study is to compare the results between patients without severe patellofemoral arthritis and patients with severe patellofemoral arthritis after mobile bearing UKA.
- Trial name
- NCT02557763
- Testing
- Oxford unicompartmental knee arthroplasty
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Post Operative Pain, Acute, Sedation Score
Patient Control Epidural Versus Conventional Epidural.
As one of the complications of THR is post operative pain, which usually requires epidural catheter insertion. We are comparing the effect of patient control epidural versus conventional epidural for patient's satisfaction.
- Conditions
- Post Operative Pain, Acute, Sedation Score, Degree of Motor Block, Length of Hospital Stay
- Trial name
- NCT06721000
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College