Clinical trials: Pain Severity
Post Herpetic Neuralgia
Efficacy, Tolerability, and Safety of NXN-462 in Patients With Post-Herpetic Neuralgia
The purpose of this study is to investigate whether NXN-462, a selective nNOS inhibitor, is effective in reducing pain levels in patients with post-herpetic neuralgia.
- Trial name
- NCT01748877
- Testing
- NXN-462
- Where
- 25 sites in United States, Canada
- Volunteers
- 188 people
- Sponsor
- NeurAxon Inc.
Pain
The Effect of Warming and Vibration Applications on Pain in Newborns
This study aimed to determine the effects of warming and vibration applications on pain during heel blood collection in newborns. H1: Warming application has a positive effect on pain during heel blood collection in newborns.
- Trial name
- NCT06607575
- Testing
- Control group, Warming, Vibration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Endometriosis
BGS649 Monotherapy in Moderate to Severe Endometriosis Patients
This study will assess the safety and tolerability of BGS649 in women with moderate to severe endometriosis.
- Trial name
- NCT01190475
- Testing
- Active treatment with a high dose of BGS649, Active treatment with a low dose of BGS649
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mereo BioPharma
Pain
Do Emotions Affect Mechanical Pain Thresholds?
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds.
- Trial name
- DEAMPT (NCT06074575)
- Testing
- Emotion induction
- Where
- Sweden
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Joint Pain
Comparison Between Retrolaminar and Medial Branch Block in Cervical Facet Joint Arthropathy
Cervical facet joints have been implicated as a source of chronic pain in 54-67 % patients with chronic posterior neck pain.1 Intraarticular injections, medial branch nerve blocks and neurolysis of medial branch nerves have been…
- Trial name
- NCT05184881
- Testing
- Retrolaminar block, Medial Branch Block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Coronary Artery Disease, Chest Pain
Imaging Studies With GE C-Hawk Gamma Camera Compared to Routine Clinical Exam
Comparison study of myocardial perfusion SPECT imaging with current clinical use camera and new camera.
- Trial name
- NCT00256581
- Testing
- Additional rest and stress image sets on new camera
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Wisconsin, Madison
Cervicogenic Headache, Central Sensitization
Central Sensitization and Neuropathic Pain in Cervicogenic Headache
Cervicogenic headache is a type of secondary headache that originates from the structures of the neck and can spread toward the head and facial regions.
- Conditions
- Cervicogenic Headache, Central Sensitization, Neuropathic Pain
- Trial name
- NCT07292181
- Testing
- Clinical assessment with standardized questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Pain, Anxiety
Virtual Reality During the Removal of Chest Drains in Critically-ill Patients
Appropriate pain and anxiety management of critically-ill patients during bedside procedures remains a big challenge. Clinical Practice Guidelines recommend preemptive analgesia or non-pharmacological interventions, such as…
- Trial name
- NCT05332119
- Testing
- VR glasses, Control group
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Gemma Via Clavero
Acupuncture, Acute Low Back Pain
The Evaluation of Single Acupoint Therapy to Acute Low Back Pain
Low back pain is the leading course of disability , affecting patients' health and work. Recently, studies have reveal the fact that patients get insufficient physical activity and easily let acute stage turn to chronic type.
- Trial name
- NCT04328428
- Testing
- acupuncture
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pain During and After Endovenous Laser Obliteration of Large Saphenous Vein Based on Lidocaine Tumescent Concentration
Efficacy of Variable Lidocaine Concentrations in Tumescent Anesthesia for Pain Control During and After Endovenous Laser Procedure; Non-inferiority Trial
Endovenous laser treatment is a minimally invasive procedure that has been shown to be a safe and effective treatment for varicose veins.
- Trial name
- NCT02192411
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Midwest Vein Center
Cervical Radiculopathy
Transcutaneous Electrical Nerve Stimulation Versus Repetitive Transcranial Magnetic Stimulation on Pain and Functional Outcome in Cervical Radiculopathy
this study will be conducted to compare between transcutaneous electrical nerve stimulation versus repetitive transcranial magnetic stimulation on pain and functional outcome in cervical radiculopathy
- Trial name
- CR (NCT07557511)
- Testing
- Transcutaneous Electrical Nerve Stimulation, repetitive Transcranial Magnetic Stimulation
- Volunteers
- 50 people
- Sponsor
- Cairo University
Surgery, Anesthesia
Postoperative Pain and Discomfort After Orbital Decompression
The purpose of this study is to evaluate the postoperative pain and discomfort using flurbiprofen axetil or nalbuphine administration after orbital decompression under general anesthesia.
- Conditions
- Surgery, Anesthesia, Pain
- Trial name
- NCT03562611
- Testing
- Nalbuphine, Flurbiprofen Axetil, Nalbuphine and Flurbiprofen Axetil
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Sun Yat-sen University
Anal Fissure, Anal Fistula
Ultrasound Guided Caudal Block for Benign Anal Surgery
Interventional study that evaluate analgesia and side effects of Ultrasound guided Caudal block preoperatively in benign canal anal surgery
- Conditions
- Anal Fissure, Anal Fistula, Hemorrhoids, Pain, Postoperative
- Trial name
- NCT03345511
- Testing
- Ultrasound Guided Caudal Block
- Where
- Colombia
- Volunteers
- 23 people
- Sponsor
- Universidad de Antioquia
Pain
Comparison of Two Lidocaine Administration Techniques
The objective of our study is to determine if technique of lidocaine administration can decrease pain perception. Hypothesis: There will be a significant difference in pain perception between patients who are given lidocaine on…
- Trial name
- NCT01330134
- Testing
- lidocaine
- Where
- United States
- Volunteers
- 481 people
- Sponsor
- University of Chicago
Stroke, Rehabilitation
The Kinesio-taping for the Prevention of Painful Shoulder and for the Functional Recovery of Upper Limb After Stroke
This RCT aims to investigate the effectiveness of the early use of Kinesio-taping (KT) together with standard physiotherapy treatment, in the prevention of the shoulder pain of the hemiplegic upper limb following a cerebral…
- Trial name
- NCT05156164
- Testing
- Kinesio Tape Group, Control Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Pain Management
MCID and PASS for Acute Pain and Quality of Recovery After Orthopedic Surgery
This study seeks to define what constitutes an MCID and a PASS in patients undergoing a variety of elective major orthopedic surgery.
- Trial name
- NCT04811209
- Testing
- 1.Baseline Measurements Before Surgery, 2.Intraoperative Anesthetic Management, 3.Postoperative Analgesic Management
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University Health Network, Toronto
Chronic Shoulder Pain
Platelet Rich Plasm Versus Hyaluronic Acid Injection in Chronic Painful Shoulder
Aim of This study is to compare between the effect of ultrasound-guided local injection of Platelet Rich Plasma (PRP)versus Hyaluronic (HA) for the treatment of chronic shoulder pain.
- Trial name
- NCT05072899
- Testing
- platelet rich plasm, Hyaluronic acid
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Sleep Disorder
Postoperative Sleep Quality and Pain of Patients After Video-Assisted Thoracoscopic Surgery
The goal of this clinical trial is to to explore the effect of perioperative transcutaneous acupoint acupuncture and moxibustion stimulation on sleep quality and postoperative chronic pain in patients undergoing thoracoscopic…
- Trial name
- PSQ (NCT06633432)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Nerve Pain
Ultrasound Guided Radiofrequency Ablation of the Occipital Nerve
Study an ultrasound guided approach to radiofrequency ablation of the occipital nerve that makes it possible to see the needle during treatment procedure.
- Trial name
- NCT06583122
- Testing
- Ultrasound Guided Approach
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Burns
A Postmarket Randomized Study of the Treatment of Superficial Partial-Thickness Burns Using Two Dressings
The purpose of this research study is to compare the rate of healing, the infection or complication rate, pain perception and scarring from burn injuries using two types of burn dressings.
- Trial name
- NCT01067729
- Testing
- AWBAT Wound Dressing, AWBAT™, Biobrane®
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aubrey Inc.
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