Clinical trials: Pain Severity
Adult Intracranial Tumor, Adult Solid Tumor
A Comparison of Remifentanil and Dexmedetomidine for Craniotomy Perioperative Hemodynamics and Postoperative Pain
This will be a randomized blinded clinical trial. Patients will be randomized to receive either a remifentanil or dexmedetomidine infusion for general anesthesia.
- Trial name
- RemivsDex (NCT01269918)
- Testing
- Remifentanil, Dexmedetomidine
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- The Cleveland Clinic
Symptomatic Irreversible Pulpitis (SIP), Dental Pain
Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial
This multicenter randomized trial compares the clinical effectiveness of intraligamentary injection versus inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in mandibular molars.
- Conditions
- Symptomatic Irreversible Pulpitis (SIP), Dental Pain, Inferior Alveolar Nerve Block Failure, Local Anesthesia
- Trial name
- NCT07130760
- Testing
- Intraligamentary Injection, Inferior Alveolar Nerve Block
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aula Dental Avanzada
Korean, Male
The Effect of Education on Decreasing the Prevalence and Severity of Neck and Shoulder Pain
Neck and shoulder pain (NSP) is fairly common among high school students in Korea. Presumably, the high prevalence of NSP in Korean adolescents is a consequence of an inappropriate static position for a prolonged period of time.
- Conditions
- Korean, Male, Adolescents
- Trial name
- NCT01727960
- Testing
- Education and posture correction
- Where
- South Korea
- Volunteers
- 1,302 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Chronic Low-back Pain (cLBP)
Yoga and Mindfulness for Chronic Low Back Pain: A Randomized Controlled Trial
Chronic low back pain (CLBP) is a leading cause of disability, significantly impacting quality of life and work productivity. Traditional treatments often provide limited relief, necessitating alternative approaches.
- Trial name
- NCT06910982
- Testing
- Sphinx Pose Yoga Therapy
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- University of Karachi
Breast Cancer, Chronic Pain
Effect of Chemotherapy on Pain Sensitivity and Patient-reported Symptoms
Many breast cancer survivors report chronic pain that develops or worsens following chemotherapy. The impact of chemotherapy on the development of chronic pain is uncertain.
- Trial name
- NCT01983982
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Knee Arthritis Osteoarthritis
Effects of Motivational Interviewing on Pain Self-Efficacy and Exercise Behavior in Individuals With Knee Osteoarthritis
This randomized controlled trial aims to investigate the effects of motivational interviewing added to a neuromuscular exercise and home exercise program on pain self-efficacy, exercise behavior, pain intensity, physical…
- Trial name
- NCT07767812
- Testing
- Motivational Interviewing, Neuromuscular Exercise Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Kutahya Health Sciences University
Dry Eye Syndromes, Keratoconjunctivitis Sicca
Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease
The primary purpose of this study is to determine the efficacy and safety of KPI-121 0.25% ophthalmic suspension compared to vehicle (placebo) in subjects who have a documented clinical diagnosis of dry eye disease.
- Trial name
- STRIDE 1 (NCT02813265)
- Testing
- KPI-121 0.25% Ophthalmic Suspension, Vehicle of KPI-121 0.25% Ophthalmic Suspension
- Where
- 60 sites in United States
- Volunteers
- 918 people
- Sponsor
- Kala Pharmaceuticals, Inc.
Postoperative Analgesia, Hand Strength
Long-term Outcomes of Breast Cancer Patients After Wound Infiltration Analgesia
In the study that was conducted from 05.01.2009 - 31.12.2012. 120 patients were examined. By drawing random numbers, the patients were randomized into 3 groups for postoperative analgesia: 1. Diclofenac 2 mg/kg/day - control, 2.
- Conditions
- Postoperative Analgesia, Hand Strength, Health Related Quality of Life, Chronic Shoulder Pain
- Trial name
- NCT05829707
- Testing
- Diclofenac Sodium, Levobupivacaine bolus analgesia, Levobupivacaine PCA group
- Volunteers
- 120 people
- Sponsor
- Osijek University Hospital
Noncardiac Chest Pain (NCCP)
Role of Esophageal Mast Cell Activation in Noncardiac Chest Pain (NCCP)
Chest pain is a common clinical complaint. About 30% patients with chest pain will have a normal coronary angiogram and are described as having noncardiac chest pain (NCCP).
- Trial name
- NCT00219492
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Achilles Tendinopathy, Tendon Injuries
Comparison of Alfredson and Silbernagel Protocol in Competitive Athletes With Achilles Tendinopathy
A 6-week randomized clinical trial (RCT) with a 46-week follow-up compared the effect of Alfredson and Silbernagel eccentric programs for the treatment of AT.
- Conditions
- Achilles Tendinopathy, Tendon Injuries, Tendon Thickening, Pain, Chronic
- Trial name
- NCT05659134
- Testing
- Alfredson protocol, Silbernagel protocol
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Charles University, Czech Republic
Pain, Postoperative
Pain Evaluation of Venous Cannulation to Predict Postoperative Pain
The investigators have recently reported a relationship between pain induced by peripheral venous cannulation and postoperative pain.
- Trial name
- NCT02982109
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Lund University
Coccyx Disorder
Analgesic Efficacy of Capsaicin 8% Patch (QUTENZA®) in Coccygodygnia
A retrospective study over a period of 6 years to explore analgesic efficacy of 8% Capsaicin patch (QUTENZA®) in coccygodynic patients, as well as neuropathic predictive factors of therapeutic response.
- Trial name
- CAPSACOXp (NCT05983263)
- Testing
- Capsaicin
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Nantes University Hospital
Chronic Pain
Management of Chronic Pain
The investigators aim to validate if a digital tool for increased self-management of chronic pain can improve the quality of life for patients with chronic pain.
- Trial name
- NCT04865263
- Testing
- Digital Pain-Management Tool
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Lund University
Genito-Pelvic Pain/Penetration Disorder, Dyspareunia
VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia
The goal of this randomized controlled trial is to determine whether the use of a novel vibrating pelvic floor therapeutic device ("Kiwi") improves sexual function in sexually active women aged 18 and older with genito-pelvic…
- Conditions
- Genito-Pelvic Pain/Penetration Disorder, Dyspareunia, Vaginismus, Pelvic Pain
- Trial name
- VIBRENT (NCT06840314)
- Testing
- Pelvic floor therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Trigger Finger, Pain
Vibratory Anesthesia in Trigger Finger Injections
This study aims to compare the effectiveness of the use of no topical anesthesia, topical coolant, and the use of vibration in the reduction of pain during trigger finger injections.
- Conditions
- Trigger Finger, Pain, Anesthesia, Local
- Trial name
- NCT05405452
- Testing
- Vibration Anesthesia Device by Blaine Labs, Gebauers Ethyl Chloride 100% Topical Spray
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Knee Osteoarthritis, Knee Pain Chronic
The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty
In our study, investigators plan to compare the preoperative RF and genicular nerve ablation approach in patients who underwent TKA(Total Knee Arthroplasty) using the Fast-Track protocol in terms of meeting postoperative pain…
- Trial name
- NCT06239649
- Testing
- Genicular nerve Radiofrequency Ablation block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Postpartum Lumbopelvic Pain, Postpartum Pelvic Girdle Pain
Osteopathy in Postpartum Lumbopelvic Pain
Postpartum lumbopelvic pain is a common condition after childbirth and may affect pain levels, physical function, daily activities, and quality of life.
- Conditions
- Postpartum Lumbopelvic Pain, Postpartum Pelvic Girdle Pain, Postpartum Low Back Pain
- Trial name
- NCT07631949
- Testing
- Core Stabilization Exercises, Patient Education, Osteopathic Manipulative Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Halic University
Chronic Pain, Opioid Use Disorder
Virtual Reality for Chronic Pain and Opioid Use Disorder Pilot
This is a pilot feasibility study of a virtual reality device for patients with co-morbid chronic pain and opioid use disorder.
- Trial name
- NCT05546749
- Testing
- RelieVRx
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albert Einstein College of Medicine
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women in spontaneous labor with whom analgesia is maintained with a combined spinal epidural (CSE)…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982838
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Myofascial Pain Syndrome
Neurophysiological Effects of Dry Needling in Patients With Neck Pain
The present study aims to evaluate the differences that may be experienced in pain and cervical disability, before, during and just after the intervention of the Deep Dry Needling in the upper trapezius muscle in active, passive…
- Trial name
- NCT03345238
- Testing
- Deep Dry Needling
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Universidad Rey Juan Carlos
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