Clinical trials: Pain-Knee
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Patellofemoral Pain Syndrome
Therapeutic Effect of Two Muscle Strengthening Programs in Patients With Patellofemoral Pain Syndrome
Introduction: The patellofemoral pain syndrome (SPF) is one of the most frequent pathologies generated by the knee joint. Conservative treatment with physiotherapy exercises reduces pain and improves functional capacity in the…
- Trial name
- NCT04011436
- Testing
- Strengthening program
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Postoperative Pain Management, Total Knee Arthroplasty
Pregabalin, Celecoxib, Total Knee Arthroplasty and Intrathecal Morphine
To evaluate whether pregabalin and/or celecoxib could improve analgesic efficacy of intrathecal morphine for patients after total knee arthroplasty.
- Trial name
- PCTKA (NCT01344213)
- Testing
- Pregabalin, Celecoxib, Pregabalin with celecoxib
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Knee Osteoarthritis (Knee OA)
Cross-linked Hyaluronic Acid in Knee Osteoarthritis
Knee Osteoarthritis (Knee OA) leads to pain and loss of function, especially in recreational athletes. While hyaluronic acid (HA) injections are a common part of conservative treatment, comparative data on the efficacy of…
- Trial name
- NCT07241442
- Testing
- Straight-bonded hyaluronic acid, cross-linked hyaluronic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Knee Osteoarthritis
Comparative Study Between Intra Articular Injection of Hyaluronic Acid (HA) With Platelet Rich Plasma (PRP) Versus Genicular Nerve Thermal Radiation in Management of Pain in Knee Osteoarthritis
Intraarticular injection (IAI) of Platelet rich plasma (PRP) with Hyaluronic acid (HA) Versus Radiofrequency (RF) of genicular nerve for pain reduction of of knee osteoarthritis , Improving daily activity and reduction analgesia…
- Trial name
- NCT04188561
- Testing
- Intra articular injection Group, Radiofrequency Group
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Arthritis Knee
Heat Application to Quadriceps Effect on Pain After a Total Knee Arthroplasty
The goal of this study is to explore an under-researched aspect of recovery. Typically, post-operative care after a knee arthroplasty consists of compression (stockings), medications, rest, ice, elevation, physical therapy, and…
- Trial name
- NCT05462483
- Testing
- Rice Sock and Instructions to heat the quadriceps.
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- The Idaho Clinic
Osteoarthritis, Knee, Pain
Pain Phenotypes in Knee Osteoarthritis
Recently, the medical community has learned damage to the knee joint may be one of many possible reasons for pain in knee osteoarthritis.
- Trial name
- NCT02664896
- Testing
- Knee Osteoarthritis, Healthy Control
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postoperative Pain
Total Knee Replacement TIVA With Robotic Arm Assisted
Total knee replacement (TKR) is a commonly performed surgical procedure, and is associated with moderate to severe acute postoperative pain.
- Trial name
- NCT04002271
- Testing
- Propofol, Sevoflurane, Spinal anaesthesia
- Where
- 2 sites in Hong Kong
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Knee Osteoarthritis
Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain
This purpose of this study is to evaluate the effectiveness and safety of the iovera° device for the temporary reduction of pain associated with knee osteoarthritis.
- Trial name
- NCT02260921
- Testing
- iovera°
- Where
- 17 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Pain
Preanalgesic Effect of Gabapentin in Total Knee Repair
The purpose of this study is to determine whether gabapentin, as a one time administration prior to a total knee replacement procedure, has opioid sparing effects and a reduction in pain scores.
- Trial name
- NCT00279487
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas Health Resources
Osteoarthritis, Knee
A Study of the Efficacy and Safety of EUFLEXXA™ for Treatment of Painful Osteoarthritis of the Knee
This multicenter, randomized, double-blind study will be performed in approximately 600 subjects with chronic idiopathic osteoarthritis (OA) of the knee. An open-label safety extension will follow.
- Trial name
- NCT00379236
- Testing
- EUFLEXXA™
- Where
- United States
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Knee Injuries and Disorders, Ankle Injuries and Disorders
Prevention of Musculoskeletal Injuries in Slovenian Armed Forces
Physical readiness of military personnel is a cornerstone of any army, as soldiers are expected to meet high physical demands on a daily basis, and soldiers must complete one hour of physical conditioning each day.
- Conditions
- Knee Injuries and Disorders, Ankle Injuries and Disorders, Low Back Pain
- Trial name
- NCT03415464
- Testing
- Exercise
- Where
- Slovenia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Hip Pain Chronic, Knee Pain Chronic
Effect of Buglossoides Oil on Recent Chronic Non-injurious Hip and Knee Pain
The effect of Buglossoides oil emulsion on the intensity of recent chronic knee and hip pain, on plasma and mononuclear blood cells fatty acid profiles and on whole blood Eicosapentaenoic acid production will be investigated.
- Trial name
- NCT03576625
- Testing
- High Oleic Sunflower Oil, Buglossoides Oil
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Réseau de Santé Vitalité Health Network
Low Intensity Knee Gonalgia
Effect of Yogurts Supplemented With Mobilee on Joint Function in Healthy Individuals With Joint Discomfort
The purpose of this study is to determine whether the daily eating of a yogurt supplemented with Mobile is effective in improving joint function and quality of life of individuals with low intensity gonalgia.
- Trial name
- NCT01303432
- Testing
- Yogurt supplemented with Mobilee, Yogurt
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Osteoarthritis, Knee
A Comparison Between GLA:D Canada and an Individualized JointEffort Exercise Program in Knee Osteoarthritis Patients
Osteoarthritis (OA) is the leading cause of disability worldwide and affects more than 4.4 million people in Canada (13% of Canadians).
- Trial name
- NCT03406767
- Testing
- GLA:D Canada Program, JointEffort Program
- Where
- 4 sites in Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Knee Osteoarthritis, Blood Loss
Extended Postoperative Oral Tranexamic Acid in Knee Replacement
A comparison of outcomes between use of oral tranexamic acid as compared to oral placebo in the first days after total knee replacement will be made to determine impact on clinical indications and patient reported outcomes.
- Conditions
- Knee Osteoarthritis, Blood Loss, Pain, Postoperative
- Trial name
- NCT05099276
- Testing
- Tranexamic Acid Pill
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Campbell Clinic
Osteoarthritis of the Knee
Knee Osteoarthritis Risk in Retired Professional Footballers
The OA and Football Study is an epidemiological study designed to establish the prevalence of knee osteoarthritis in retired professional footballers.
- Trial name
- NCT02098044
- Where
- United Kingdom
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Anterior Knee Pain Syndrome
Yoga for Adolescent Knee Pain
Adolescent atraumatic anterior knee pain is a common yet cumbersome diagnosis that is currently managed with home exercises and physical therapy.
- Trial name
- NCT06031935
- Testing
- Yoga
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic
Knee Osteoarthristis
Mobile App Use for Physical Activity in Knee Osteoarthritis
The goal of this clinical trial is to evaluate the effectiveness of an app developed to provide useful guidance on physical activity for people with knee osteoarthritis.The main question it aims to answer is: "What physical…
- Trial name
- moveforknee (NCT06721208)
- Testing
- use the "Move for Knee" APP
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli