Clinical trials: Painful Bladder Syndrome (PBS)
Osteoarthritis of the Knee
Gel-200 Versus Placebo in Osteoarthritis of the Knee
The purpose of this study is to determine if a single intra-articular injection of Gel-200 is superior to a single injection of Phosphate Buffered Saline (PBS) in subjects with symptomatic osteoarthritis of the knee.
- Trial name
- NCT00449696
- Testing
- Gel-200
- Where
- United States
- Volunteers
- 379 people
- Sponsor
- Seikagaku Corporation
Interstitial Cystitis/Painful Bladder Syndrome, Interstitial Cystitis, Chronic
Evaluation of Hyivy Floora in Managing Interstitial Cystitis/Bladder Pain Syndrome/High-tone Pelvic Floor Dysfunction
The purpose of this study is to test the safety and effectiveness of the Floora Pelvic Rehabilitation Vaginal Dilator in females with Interstitial Cystitis/ Bladder pain Syndrome (IC/BPS) and High-tome Pelvic Floor Dysfunction…
- Conditions
- Interstitial Cystitis/Painful Bladder Syndrome, Interstitial Cystitis, Chronic, High Tone Pelvic Floor Dysfunction
- Trial name
- NCT07038512
- Testing
- Floora Pelvic Rehabilitation Vaginal Dilator
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis, Painful Bladder Syndrome
Omalizumab in Interstitial Cystitis/Bladder Pain Syndrome
By hypothesising that Interstitial Cystitis is an allergic disorder of the urogenital system that is linked to mast-cells, current therapy with omalizumab may represent a potential non symptomatic strategy for the treatment of…
- Trial name
- IComaliz (NCT01294878)
- Testing
- omalizumab
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Interstitial Cystitis and Bladder Pain Syndrome
Real-world Evidence Study on Cystistat
This study will be conducted with the aim of ensuring the continued acceptability of the benefit-risk ratio and confirming the safety and performance of the device throughout its expected lifetime.
- Trial name
- IC/BPS (NCT05544695)
- Testing
- intravesical sodium hyaluronate (Cystistat®)
- Where
- Austria
- Volunteers
- 74 people
- Sponsor
- MEDA Pharma GmbH & Co. KG
Interstitial Cystitis and Bladder Pain Syndrome
Learning to THRIVE (L2T) Program Pilot
This pilot study evaluated the feasibility and potential effects of Learning to THRIVE (L2T), a six-week online educational self-management program for adults who self-identified as women or female and had interstitial…
- Trial name
- L2T (NCT07797010)
- Testing
- Learning to THRIVE (L2T) Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Indianapolis
Interstitial Cystitis, Painful Bladder Syndrome
Efficacy and Safety Study of Uracyst to Treat Interstitial Cystitis/Painful Bladder Syndrome
A new device for interstitial cystitis is compared to inactive control to determine if it is safe and effective. The study lasts approximately 7 weeks with a 19-week follow-up period.
- Trial name
- NCT00919113
- Testing
- 2% sodium chondroitin sulfate
- Where
- 20 sites in United States
- Volunteers
- 98 people
- Sponsor
- Watson Pharmaceuticals
Fibromyalgia, Irritable Bowel Syndrome
Observational Study of Control Participants for the MAPP Research Network
The Control Study for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
- Trial name
- MAPP-Control (NCT01098292)
- Where
- 8 sites in United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Interstitial Cystitis, Bladder Pain Syndrome
What is the Optimal Technique for Hydrodistention?
This research study is being done to learn what is the best way to perform hydrodistention. Eligible participants will be enrolled and have follow-up for three months after surgery.
- Trial name
- NCT05456308
- Testing
- Hydrodistention during cystoscope
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Michigan
Overactive Bladder, Urinary Urge Incontinence
Reduction of Bladder Injection Pain With Belladonna Opiate Suppository
The purpose of this study is to test whether using belladonna \& opiate suppositories (B\&Os) can improve patient discomfort during Onabotulinumtoxin A (BoNT) injection into the bladder for treatment of overactive bladder…
- Conditions
- Overactive Bladder, Urinary Urge Incontinence, Urinary Bladder, Neurogenic, Painful Bladder Syndrome
- Trial name
- ROBIN (NCT02600715)
- Testing
- Onabotulinumtoxin A (BoNT), belladonna, Morphine
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Edgar LeClaire, MD
Interstitial Cystitis, Chronic Interstitial Cystitis
Investigation of PEMF Therapy for Female Patients With IC/BPS
The purpose of this study is to gather information about the safety and effectiveness of the non-pharmacological (non-drug), non-invasive treatment known as low-frequency pulsed electromagnetic field (PEMF) therapy.
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT05149573
- Testing
- Pulsed Electromagnetic Field (PEMF) Device
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Wake Forest University Health Sciences
Bladder Pain Syndrome, Interstitial Cystitis
A Study to Investigate Efficacy, Safety, Pharmacodynamics and Pharmacokinetics of ASP6294 in the Treatment of Female Subjects With Bladder Pain Syndrome/Interstitial Cystitis
The purpose of this study is to investigate efficacy, safety and tolerability of ASP6294 in female participants with Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC).
- Trial name
- SERENITY (NCT03282318)
- Testing
- ASP6294
- Where
- 28 sites in Belgium, Czechia and 8 more
- Volunteers
- 119 people
- Sponsor
- Astellas Pharma Europe B.V.
Bladder Pain Syndrome
Comparative Study Suburothelial and Trigonal Botulinum Toxin A Injection in Treatment of Interstitial Cystitis
There is no consensus of the therapeutic efficacy and safety between suburothelial injection and trigonal injection of botulinum toxin A (BoNT-A) in treatment of interstitial cystitis/bladder pain syndrome (IC/BPS) It is unmet to…
- Trial name
- NCT03076762
- Testing
- intravesical onabotulinumtoxinA injection
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Substance Abuse, Mental Health
Implementing School Wide PBS in Middle Schools: The Foundation for Effective Prevention
The research study will experimentally evaluate the impact of PBS on early adolescent development through a randomized control trial involving 36 middle schools.
- Trial name
- NCT04711681
- Testing
- Positive Behavior Supports in Middle Schools
- Where
- United States
- Volunteers
- 13,498 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Interstitial Cystitis, Bladder Pain Syndrome
Intradetrusor Triamcinolone Injection in the Management of Interstitial Cystitis/Bladder Pain Syndrome
This initial pilot project aims to study the use of FDA-approved 40mg triamcinolone injections in the bladder for the management of interstitial cystitis with or without Hunner's lesions.
- Trial name
- NCT05226832
- Testing
- 40mg Triamcinolone Injections in the Bladder
- Sponsor
- The University of Texas Medical Branch, Galveston
Interstitial Cystitis, Bladder Pain Syndrome
Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome
Interstitial cystitis / bladder pain syndrome (IC/BPS) is a debilitating condition that affects millions of women in the United States.
- Trial name
- T3STOPBPS (NCT05485207)
- Testing
- Transvaginal botulinum toxin A (BTA) injection
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Interstitial Cystitis
Urinary Biomarkers Characteristic to Interstitial Cystitis
This is a retrospective study of urine samples stored in the Beaumont BioBank for future research. The urine samples will be drawn from the urine back with patients previously diagnosed with severe interstitial cystitis (IC)…
- Trial name
- NCT00971568
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Corewell Health East
Bladder Pain Syndrome
The Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Female Participants With Interstitial Cystitis /Bladder Pain Syndrome (MK-7264-005)
The purpose of this study is to assess the efficacy of gefapixant (AF-219/MK-7264) in female participants with moderate to severe pain associated with interstitial cystitis/bladder pain syndrome (IC/BPS) after 4 weeks of…
- Trial name
- NCT01569438
- Testing
- Gefapixant
- Where
- 41 sites in United States
- Volunteers
- 107 people
- Sponsor
- Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Interstitial Cystitis, Painful Bladder Syndrome
Physical Therapy Trial for Pelvic Pain
The purpose of this study is to determine if a randomized trial of physical therapy for pelvic pain is feasible.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Chronic Prostatitis, Chronic Pelvic Pain Syndrome
- Trial name
- UPPCRN-RCT#1 (NCT00434343)
- Testing
- Global Therapeutic Massage (GTM), Myofascial physical therapy (MPT)
- Where
- 5 sites in United States
- Volunteers
- 47 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Interstitial Cystitis, Painful Bladder Syndrome
IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a debilitating condition with symptoms of urinary urgency, frequency, nocturia (waking up at night to void), and pain, without evidence of urinary tract infection or…
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Bladder Pain Syndrome, Low Dose Naltrexone
- Trial name
- NCT04313972
- Testing
- low-dose naltrexone
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Hodgkin Lymphoma
Clinical Investigation of Proton Treatment in Hodgkin Lymphoma Patients - PRO-Hodgkin
Hodgkin Lymphoma patients with limited stage are commonly cured with limited chemotherapy followed by radiotherapy. Studies have shown a risk of late toxicity from the radiotherapy, such as second cancer, heart failure and lung…
- Trial name
- PRO-Hodgkin (NCT06883604)
- Testing
- Proton therapy.
- Where
- 6 sites in Sweden
- Volunteers
- 75 people
- Sponsor
- Uppsala University Hospital