Clinical trials: Palate; Wound
Healing Wound
Adjunctive Use of an Antibacterial Honey Dressing for Palatal Wound Healing After Harvesting a Free Gingival Graft
This case-control study will afford a more understanding of the clinically benefits that the antibacterial honey dressing material has in palatal wound healing and the subsequent effects in post-operative morbidity.
- Trial name
- NCT04269694
- Testing
- Medihoney dressing
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Wound Heal
Effect of Melatonin on Palatal Wound Healing (Randomized Controlled Clinical Trial)
The aim of the study is to assess the effect of topical melatonin loaded gelatin sponge on donor palatal site healing, after palatal graft harvesting.
- Trial name
- NCT05122130
- Testing
- Melatonin, Carbopol
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Salma Nabil
Wound Heal
The Effect of Two Different Approaches on Palatal Donor Site
An epithelialized gingival graft will be harvested from the palate for the treatment of various mucogingival deformities. The donor site will be treated with either a combination of a collagen sponge, cyanoacrylate and suspending…
- Trial name
- NCT06583226
- Testing
- Gelatin sponge stabilization with suture and cyanoacrylate, Gelatin sponge stabilization with suture and cyanoacrylate and coconut oil application
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medipol University
Gingival Recession, Palate; Wound
Ultrasonographic Assessment of Palatal Wound Healing
Palatal-tissue harvesting is a routinely performed procedure in periodontal plastic surgery. Subepithelial connective tissue graft (sCTG) is considered the gold standard in root coverage.
- Trial name
- NCT06118177
- Testing
- connective tissue harvesting, ultrasonography, autolog platelet rich fibrin application
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Wound Heal, Wound Surgical
Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part II
The purpose of the present study is to evaluate the influence of the post-surgical chlorhexidine indication in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the…
- Conditions
- Wound Heal, Wound Surgical, Oral Soft Tissue Conditions, Chlorhexidine Adverse Reaction
- Trial name
- NCT04276129
- Testing
- periodontal surgery + 24 hr buccal attached gingiva (G) biopsy, post-surgical CHX mouth-rinses indication
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- University of Roma La Sapienza
Wound Healing Complication
Effect of Topically-Applied Hyaluronic-Acid on Palatal Epithelial Wound Closure
Aim of the study is to assess the therapeutic effects of topical hyaluronic-acid use on secondary wound healing of the free gingival graft donor site.
- Trial name
- NCT02534415
- Testing
- Periodontal dressing material, 0.2% Hyaluronic acid gel, 0.8% Hyaluronic acid gel
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Marmara University
Wound Heal, Graft Pain
The Effectiveness of Different Methods for Healing a Palatal Donor Site
Postoperative complications associated with free gingival graft (FGG) procedures are prolonged bleeding from the donor site, postoperative pain and delayed wound healing which increases the patients' morbidity.
- Conditions
- Wound Heal, Graft Pain, Palate; Wound
- Trial name
- NCT03567148
- Testing
- PRF, Essix retainer, Ozone therapy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gazi University
Low Level Laser Therapy, Healthy
Effect of GaAlAs 940 Laser on Pain and Wound Healing After Free Gingival Graft
This randomized controlled clinical trial aims to evaluate the biomodulatory effects of a 940-nm GaAlAs diode laser on postoperative pain control and wound healing at the palatal donor site following free gingival graft…
- Conditions
- Low Level Laser Therapy, Healthy, Postoperative Pain Management, Wound Healing
- Trial name
- NCT07308912
- Testing
- 940 nm GaAlAs diode laser, palatal stent
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Pain, Postoperative, Healing Surgical Wounds
Use of Cyanoacrylate in Healing and Pain in the Palatal Donor Site of Connective Tissue Grafts
Periodontal plastic surgery has been performed successfully for a long time in the treatment of gingival recessions and mucogingival defects.
- Trial name
- NCT06116539
- Testing
- Cyanoacrylate, Suture
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alfonso X El Sabio University
Palatal Wound
Clinical and Histological Outcomes of Allogenic Amnion Chorion Membrane in the Healing of Free Gingival Graft Donor Site
The purpose of this study is to compare an allogenic amnion chorion membrane to a collagen dressing in palatal wound healing after harvesting free gingival graft (FGG).
- Trial name
- NCT03713073
- Testing
- Allogenic amnion chorion membrane, Collagen dressing
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The University of Texas Health Science Center, Houston
Palatal Expansion Technique
Investigation of Skeletally Anchored Expansion of the Maxilla
This study aims to compare two different methods for maxillary expansion in adult patients with transverse maxillary deficiency. Participants will receive either miniscrew-assisted rapid palatal expansion (MARPE-MICRO-4).
- Trial name
- NCT07383376
- Testing
- MARPE, SARME
- Where
- Hungary
- Volunteers
- 90 people
- Sponsor
- Semmelweis University
Pain, Postoperative, Gingival Diseases
Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery
When harvesting autogenous free grafts to treat periodontal conditions (e.g., lack of attached keratinized tissue, ridge defects, and other mucogingival deformities), the hard palate is the preferred donor site.
- Trial name
- NCT04957342
- Testing
- amnion-chorion membrane, Sutures
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Serous Otitis, Tympanic Membrane Perforation
Otological Study of Facial Cleft Patients Over 10 Years of Age (Excluding Isolated Cleft Lip) (EFEOF)
Studies published on the placement of transtympanic ventilatory tubes in children with cleft palate show heterogeneous results, highlighting the need for a new study with strong statistical power and long-term follow-up to…
- Conditions
- Serous Otitis, Tympanic Membrane Perforation, Retraction Pocket, Cholesteatoma
- Trial name
- EFEOF (NCT06738927)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Brest
Palatal Donor Site Wound Healing
Effect of Frankincense Versus Palatal Stent on Palatal Donor Site Healing
This randomized controlled clinical trial will evaluate the effect of a natural frankincense-based gel on healing of the palatal donor site after soft tissue graft harvesting.
- Trial name
- NCT07772011
- Testing
- Frankincense Gel, Palatal stent
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Palatal Wound
Wound Healing and Patient-Reported Outcomes After Gingival Graft Harvesting From the Palate
The goal of this clinical trial is to evaluate whether two different techniques for treating palatal wounds-sutures and cyanoacrylate bioadhesive-can influence postoperative morbidity, clinical healing, and soft tissue…
- Trial name
- NCT06806111
- Testing
- Suture, Cyanoacrylate bioadhesive
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Universitat Internacional de Catalunya
Mucosal Erosion, Gingival Recession
Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques
This study has been initiated to evaluate the question, "What is the best way to protect the palate after a gum graft is removed?" The overall objective is to determine if there is a difference in PROMs of donor site healing…
- Trial name
- NCT06892496
- Testing
- Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Virginia Commonwealth University
Wound Healing
Effect of Leucocyte- and Platelet-Rich Fibrin on Palatal Wound Healing After Free Gingival Graft Harvesting
Autogenous palatal free gingival graft harvesting presents challenges for patients due to the increased risk of postoperative morbidity related to a second intraoral surgical wound that heals with secondary intention.
- Trial name
- NCT06777069
- Testing
- Leucocyte and platelet rich fibrin membrane application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Istanbul Medipol University Hospital
Postoperative Pain, Mucogingival Defects
Management of Postoperative Pain Following Free Gingival Graft Harvesting Using Ora-Aid Versus Acrylic Palatal Stent
This randomized clinical trial evaluates the effectiveness of Ora-Aid oral wound dressing compared to an acrylic palatal stent in managing postoperative pain following free gingival graft harvesting.
- Conditions
- Postoperative Pain, Mucogingival Defects, Gingival Recessions
- Trial name
- NCT07523802
- Testing
- Ora-Aid Oral Wound Dressing, Acrylic Resin Palatal Stent
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Cleft Lip and/or Palate, Distraction of Bone
Tooth-borne Interdental Distraction Osteogenesis Along Arch Curvature for Wide Alveolar Clefts Reduction
This clinical study provided a modified simple and small appliance for reduction of wide alveolar clefts in cleft lip and palate patients, making the grafting procedure of better prognosis and increase its success rate.
- Trial name
- IDO (NCT07578207)
- Testing
- Tooth borne Interdental distraction appliance with mini hyrax screw
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Gingival Recession
Platelet-Rich Fibrin Dressing in the Management of Free Gingival Graft
Evaluation of two dressing materials; a Platelet-Rich Fibrin (PRF) dressing and a non-eugenol-based (Coe-Pak™) dressing in the management of free gingival graft and donor site palatal wound.
- Trial name
- NCT03589235
- Testing
- A free gingival graft, A Platelet-Rich Fibrin dressing, A non-eugenol-based dressing
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University