Clinical trials: Palliative Cancer
Constipation, Neoplasms
Constipation in Pediatric Cancer Patients Receiving Vinca Alkaloids or Narcotics
This study will evaluate a questionnaire for measuring constipation in children with cancer. The questionnaire used in this study (Constipation Assessment Scale) reliably predicts the presence and severity of constipation in…
- Trial name
- NCT00032682
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Rectal Cancer
Exercise During and After Neoadjuvant Rectal Cancer Treatment
This study is designed to investigate if aerobic exercise during and after neoadjuvant chemoradiotherapy (NACRT) can improve outcomes for rectal cancer patients.
- Trial name
- EXERT (NCT03082495)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Alberta
Squamous Cell Carcinoma of Head and Neck
Prognostic Counselling in Palliative Head and Neck Cancer (ProCoPall)
The investigators test the effect of providing individualized prognostic information on life-expectancy to head and neck cancer patients in the palliative phase.
- Trial name
- ProCoPall (NCT06699316)
- Testing
- Individualized prognostic counselling
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- Erasmus Medical Center
Cancer
Understanding Quality of Life Among Patients With Cancer Receiving Palliative Care
This randomized controlled trial will assess the effects on quality of life of two approaches to symptom management among new patients referred to a palliative care oncology clinic.
- Trial name
- NCT05331625
- Testing
- Offering Additional Resources to Promote Symptom Management
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Virtual Reality for Symptom Management in Patients Undergoing Hematopoietic Stem Cell Transplantation
This clinical trial compares the use of virtual reality to standard care for improving symptom management in patients undergoing hematopoietic stem cell transplantation (HSCT).
- Trial name
- NCT06798701
- Testing
- Best Practice, Interview, Survey Administration
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Roswell Park Cancer Institute
Advanced Cancer
Family and Coping Oriented Palliative Homecare Nursing Aimed at Advanced Cancer Patients
When facing life threatening illness such as advanced cancer palliative care is needed to improve quality of life of patients and their families through the prevention and relief of suffering.
- Trial name
- FamCope (NCT01444157)
- Testing
- Palliative homecare nursing
- Where
- 3 sites in Denmark
- Volunteers
- 700 people
- Sponsor
- Bispebjerg Hospital
Cervical Cancer
Palliative Radiation for Advanced Cervical Cancer
The present study is proposed to compare a rapid fractionation schedule of 1 week compared to a protracted schedule of 6-8 weeks for palliation for locally advanced cervical cancer.
- Trial name
- RAPPAL (NCT03997110)
- Testing
- Short course palliative radiation., Long course palliative treatment.
- Where
- India
- Volunteers
- 230 people
- Sponsor
- Tata Memorial Hospital
Cancer, Solid Tumor Cancer
Feasibility and Acceptability of the Remote Oncology Symptom Assessment Application
The goal of this study is to determine whether a mobile application that combines real-time sensor data and patient-reported symptoms to trigger care-team contact recommendations is feasible and beneficial for patients receiving…
- Conditions
- Cancer, Solid Tumor Cancer, Chemotherapy
- Trial name
- ROSA App (NCT07218874)
- Testing
- Mobile Symptom Monitoring and Alert App
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Pittsburgh
Cancer, Nutrition Disorders
Co-designed Nutritional Training Program for Oncology Nurses in Vietnam
This study evaluates a co-designed nutritional training program for oncology nurses in Vietnam. The aim is to improve nurses' knowledge, confidence, and clinical practice in providing nutritional support for patients with cancer…
- Conditions
- Cancer, Nutrition Disorders, Chemotherapy-Related Symptoms
- Trial name
- NUTRI-NURSE-VN (NCT07566169)
- Testing
- Co-Designed Nutritional Training Program
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VinUniversity
Medical Oncology, Cardiology
Results From a Health System-wide Implementation of a Quality of Life Questionnaire
The purpose of this retrospective chart review pilot study is to research the results and scores of the QOL questionnaire implemented across Allina Health clinics.
- Conditions
- Medical Oncology, Cardiology, Integrative Medicine, Physical and Rehabilitation Medicine
- Trial name
- NCT02906423
- Testing
- PROMIS-10 questionnaire
- Where
- United States
- Volunteers
- 43,000 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Cancer
Safety and Tolerability of NOX66 in Combination With Palliative Radiotherapy in Patients With Late-Stage Prostate Cancer
The study is intended as a Proof of Concept and dose confirmation study. The primary objective of this study is to observe safety and tolerability of idronoxil (NOX66) in combination with radiotherapy (at palliative doses) in…
- Trial name
- NCT03307629
- Testing
- NOX66, Irradiation Therapy
- Where
- 10 sites in Australia, Georgia and 1 more
- Volunteers
- 25 people
- Sponsor
- Noxopharm Limited
Pain Cancer
Subcutaneous Versus Intravenous Morphine When Switching From Oral to Parenteral Route in Palliative Cancer Patients
The investigators aim to establish whether the intravenous or the subcutaneous route of administration has clinically significant advantages when parenteral administration of morphine is started with a combination of continuous…
- Trial name
- SIM (NCT05236647)
- Testing
- Morphine
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital, Akershus
Oncology, Cancer Pain
Pain ASsessment in CAncer Patients by Machine LEarning (PASCALE)
In cancer patients, the integration between anticancer therapies and palliative care is of fundamental importance. In this context, telemedicine can improve the quality of life (QoL) of chronic patients through self-management…
- Conditions
- Oncology, Cancer Pain, Quality of Life
- Trial name
- PASCALE (NCT04726228)
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Naples
Lung Cancer
Palliative Care Interventions for Outpatients Newly Diagnosed With Lung Cancer: Phase II
The focus of the study is to test a nurse-led telephone-based palliative care intervention on improving the delivery of care for patients with newly diagnosed lung cancer.
- Trial name
- PCI2 (NCT03007953)
- Testing
- Palliative Care
- Where
- 3 sites in United States
- Volunteers
- 151 people
- Sponsor
- VA Office of Research and Development
Depression, Palliative Care
Methylphenidate for Depressed Cancer Patients Receiving Palliative Care
The purpose of this study is to determine whether methylphenidate is an effective treatment for depression and to document the safety and tolerability of methylphenidate in combination with an Selective Serotonin Reuptake…
- Conditions
- Depression, Palliative Care, Cancer, Mental Disorder
- Trial name
- NCT00129467
- Testing
- Methylphenidate, Selective Serotonin Uptake Inhibitor (SSRI)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- US Department of Veterans Affairs
Solid Tumor, Adult, Metastasis
Clinical Nurse Specialist Led Early Palliative Survivorship Care for Patients With Advanced Cancer
The purpose of the randomized control trial is to estimate the effect of an oncology clinical nurse specialist-led early intervention multidisciplinary approach to palliative and survivorship care within two previously identified…
- Trial name
- NCT05947695
- Testing
- Palliative and Survivorship Care Model
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Good Samaritan Hospital Medical Center, New York
Cancer, Quality of Life
Financial Distress in Patients With Advanced Cancer
Advanced cancer has an adverse effect in virtually all dimensions of patients' lives (physical, psychosocial, spiritual, familial, role function).
- Trial name
- DIFIC (NCT01868100)
- Testing
- self-completion questionnaire
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Hospices Civils de Lyon
Cancer of Head and Neck, Pain, Face
Focused Ultrasound (FUS) Mesencephalotomy for Head & Neck Cancer Pain
This proposed pilot study will investigate the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer
- Conditions
- Cancer of Head and Neck, Pain, Face, Pain, Neck
- Trial name
- NCT03894553
- Testing
- ExAblate Neuro
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Jeff Elias, MD
Esophageal Cancer
Palliative Radiotherapy and Brachytherapy for Oesophageal Cancer Dysphagia
Hypothesis: In the management of advanced oesophageal cancer, to determine if a shorter regime of external beam radiotherapy (using higher daily doses, and combined with intraluminal high dose rate brachytherapy) is not inferior…
- Trial name
- NCT00665197
- Testing
- Protracted Course Radiotherapy, Short Course Radiotherapy
- Where
- 7 sites in Canada, China and 5 more
- Volunteers
- 200 people
- Sponsor
- International Atomic Energy Agency
Colorectal Cancer
Pedometer Intervention and Health Effects for Sedentary Colorectal Cancer Patients During Adjuvant Chemotherapy
Colorectal cancer is one of the most common cancers in Denmark, annually 4,200 men and women are diagnosed and approx. 2000 patients die of their colorectal cancer.
- Trial name
- NCT02522520
- Testing
- Pedometer intervention, Pedometer + hospital based intervention, Omron Walking Style pro. 20
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
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