Clinical trials: Palliative Cancer
Advanced Head and Neck Cancer
Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer
This study is being done to answer the following question: Does stereotactic body radiation therapy (SBRT) provide better cancer control compared to standard radiation therapy (RT) for those with advanced head and neck cancer?
- Trial name
- NCT06641791
- Testing
- Standard Radiotherapy (SRT), Stereotactic Body Radiotherapy (SBRT)
- Where
- 10 sites in Canada
- Volunteers
- 196 people
- Sponsor
- Canadian Cancer Trials Group
Esophageal Cancer
Precision Palliative Care for Patients With Advanced Esophageal Cancer
The goal of this clinical trial is to learn if precision palliative care improves survival of patients with advanced esophageal cancer in adults.
- Trial name
- NCT06787313
- Testing
- precision palliative care
- Where
- China
- Volunteers
- 624 people
- Sponsor
- Fudan University
Cancer Care Providers
Better Communication, Better Care Using SICG Assistant Based on Artificial Intelligence
The project 'Better Communication, Better Care' has as its main objective to evaluate the effectiveness of the implementation of the 'Guide to conversation in serious illness (SICG)' by means of a significant reduction in anxiety…
- Trial name
- SICG-Assist (NCT07753668)
- Testing
- Intervention Group
- Where
- 2 sites in Spain
- Volunteers
- 190 people
- Sponsor
- Cudeca Hospice Foundation
Lung Cancer, Breast Cancer
Improving Cancer Outcomes Through Personalized Care Planning and Symptom Management.
This Study is a case control Study conducted with 100 patients with a solid tumor cancer diagnosis (lung, breast, or gynecologic cancer).
- Conditions
- Lung Cancer, Breast Cancer, Gynecologic Cancer
- Trial name
- NCT04772118
- Testing
- Carevive PROmpt™
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Carevive Systems, Inc.
Metastatic Malignant Neoplasm
Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer
This phase II trial studies how well single-fraction stereotactic body radiation therapy (SBRT) works when compared to standard radiation therapy in treating patients with cancer that has spread to other places in the body…
- Trial name
- NCT04068649
- Testing
- Palliative Radiation Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Roswell Park Cancer Institute
Pancreatic Cancer, Pancreatic Duct Stricture
Palliative Pancreatic Duct Stenting in Patients With Inoperable Pancreatic Cancer
Patients with pancreatic cancer often suffer from chronic abdominal pain, weight loss and decreased quality of life. The patients also often need pancreatic enzyme supplements.
- Trial name
- NCT03069664
- Testing
- ERCP, Covered Self-expandable Metal Stent
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Helsinki University Central Hospital
Ovarian Cancer
Palliative Care During Intraperitoneal Chemotherapy in Patients With Ovarian Cancer
RATIONALE: Palliative care may help improve the quality of life of patients with ovarian cancer who are undergoing intraperitoneal chemotherapy.
- Trial name
- NCT00804258
- Testing
- intraperitoneal chemotherapy, educational intervention, medical chart review
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- City of Hope Medical Center
Adolescent and Young Adult Cancer Patient
Adolescents and Young Adults (AYAs) With Advanced Cancer
This study aims to develop and test the feasibility and acceptability of a psychosocial symptom management intervention designed to meet the unique needs of Adolescents and Young Adults (AYAs) with advanced cancer.
- Trial name
- NCT05593016
- Testing
- Symptom Management for Improved Physical and Emotional Wellbeing (SMILE), Education Control Arm
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Duke University
Cancer Metastatic, Symptoms and Signs
Symptom Management and Survivorship Plus Coaching for Advanced Cancer Survivors and Their Caregivers
The protocol will include a 10-week Symptom Management and Survivorship Handbook (SMSH) intervention to address informational needs for the management of physical and psychological symptoms, bundled with telephone delivered…
- Conditions
- Cancer Metastatic, Symptoms and Signs, Quality of Life
- Trial name
- SMSH and SMSH+ (NCT07415564)
- Testing
- Symptom Management and Survivorship Handbook + Coaching, Symptom Management and Survivorship Handbook
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Arizona
Palliative Medicine, Pediatric ALL
Paediatric Palliative Care Pain Management in the Community
To describe the the barriers and facilitators experienced by carers and healthcare professionals when managing medicines for pain relief for infants, children, and young people approaching the end of life in out of hospital…
- Trial name
- PARAMOUNT (NCT04519632)
- Testing
- Qualitative study
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Squamous Cell Carcinoma of the Head and Neck
Study Comparing Two Treatments in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
In this clinical trial, the investigators want to know if cabazitaxel is more effective than methotrexate for patients with recurrent or metastatic squamous cell carcinoma of the head and neck in palliative treatment.
- Trial name
- RACATREX (NCT01528163)
- Testing
- Cabazitaxel, Methotrexate
- Where
- 16 sites in Belgium, Luxembourg
- Volunteers
- 101 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Pancreatic Cancer Metastatic to Liver
Study-group on Palliative ERCP And RFA-ablation in Metastatic and Inoperable Pancreatic Tumors
Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive cancer and may become the second leading cause of cancer death by 2030.
- Trial name
- Spearmint (NCT07191418)
- Testing
- Habib™ EndoHPB, ERCP
- Where
- Sweden
- Volunteers
- 178 people
- Sponsor
- Roberto Valente
Hepatocellular Carcinoma
Multimodality Therapy for Palliative Resectable Hepatocellular Carcinoma With Intrahepatic Vessels Invasion
The purpose of this study is to compare the effects of different multimodality therapy strategies (initial hepatectomy followed by transcatheter hepatic arterial chemoembolization and/or local regional treatments compare with…
- Trial name
- MDTforHCC (NCT00501813)
- Testing
- Hepatectomy, TACE combined with local regional therapies without hepatectomy
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Sun Yat-sen University
Colorectal Cancer
Combination Chemotherapy With or Without Cetuximab as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00182715
- Testing
- cetuximab, capecitabine, fluorouracil
- Where
- 82 sites in Ireland, United Kingdom
- Volunteers
- 2,421 people
- Sponsor
- Velindre NHS Trust
Gastric Cancer
Surgery for Obstructed Gastric Carcinoma
The goal of this clinical trial is to find the best treatment for obstructed gastric carcinoma in gastric cancer patients. It will include all patients with obstructed gastric cancer with different ages and sex who consented to…
- Trial name
- NCT07435025
- Testing
- palliative gastric resection, palliative bypass
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Zagazig University
Quality of Life
Pilot Study of Living With Hope Program
Hope is important to palliative home care patients. Our research team has developed a Living with Hope Program that has been found to increase hope and quality of life in older persons with advanced cancer.
- Trial name
- NCT01697982
- Testing
- Living with Hope Program, LWH film
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Alberta
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
This phase II trial studies whether psilocybin with psychotherapy is safe and if it works for improving chronic pain in cancer patients who require opioids to manage their pain.
- Trial name
- NCT06827054
- Testing
- Biospecimen Collection, Functional Magnetic Resonance Imaging, Interview
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Roswell Park Cancer Institute
Cancer
FAmily CEntered (FACE) Advance Care Planning for Teens With Cancer
Advance Care Planning (ACP) prepares patients and their loved ones for future health care decisions, including end-of-life decisions.
- Trial name
- FACE (NCT01670461)
- Testing
- FACE, Standard of Care (SOC) Control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maureen Lyon
Neoplasm Metastasis
Stereotactic Body Radiotherapy Followed by Surgical Stabilization for Patients With Unstable Spinal Metastases
The aim of this study is to assess the feasibility and safety of combining stereotactic body radiotherapy (SBRT) and pedicle screw fixation in a 48-hour window for the treatment of painful unstable metastases of the thoracic…
- Trial name
- BLEND (NCT02622841)
- Testing
- BLEND
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- UMC Utrecht
Carcinoma, Non-Small-Cell Lung
Palliative Thoracic Radiotherapy Plus BKM120
This study will test whether a drug called BKM120/buparlisib is a safe and effective treatment when given to lung cancer patients having radiotherapy treatment.
- Trial name
- BKM120 (NCT02128724)
- Testing
- BKM120
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Oxford
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