Clinical trials: Palliative Cancer
Family Caregivers
Improving Cancer Family Caregivers' Knowledge and Communication About Care Options
The purpose of this two-year mixed methods study is to develop and test an intervention to improve cancer family caregivers' knowledge of care options (curative, palliative, and hospice care) and goals of care communication as…
- Trial name
- NCT02616107
- Testing
- Managing Cancer Care: A Caregiver's Guide, Symptom Management Toolkit
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Yale University
Pancreatic Cancer, Periampullary Adenocarcinoma
Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma
The investigators are looking to see if a certain dose of stereotactic body radiation therapy (SBRT) may be a viable treatment option for recurrent or residual pancreatic or periampullary adenocarcinoma.
- Trial name
- NCT01781728
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Cancer, Gastrointestinal, Cancer, Lung
Influence of a Home-based Nutrition and Exercise Program on Quality of Life of Palliative Cancer Outpatients
The main purpose of the study is to investigate whether a tailor-made nutritional and exercise program including home-based sessions and regular monitoring using an application on the smartphone is effective in improving Quality…
- Conditions
- Cancer, Gastrointestinal, Cancer, Lung, Malnutrition
- Trial name
- NCT04859400
- Testing
- Whey protein supplement high in leucine and β-hydroxy-β-methylbutyrate (HMB), Standardized nutritional program, Standardized exercise program
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 72 people
- Sponsor
- Kantonsspital Winterthur KSW
Lung Cancer
Effects of Palliative Care on Quality of Life and Symptom Control in Patients With Stage I, Stage II, or Stage IIIA Non-Small Cell Lung Cancer That Can Be Removed by Surgery
RATIONALE: Palliative care may be more effective than standard care in improving quality of life and symptoms in patients with lung cancer.
- Trial name
- NCT00823667
- Testing
- educational intervention, medical chart review, questionnaire administration
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- City of Hope Medical Center
Quality of Life Outcomes
Palliative Care Integration in Pediatric Oncology Phase 1 Clinical Trials
Although cure rates continue to rise, one in five children with cancer still die from their disease, so new therapies are urgently needed.
- Trial name
- NCT07696065
- Testing
- Pediatric Palliative Care Consultation
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Phoenix Children's Hospital
Cancer, Neoplasms
Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy
New oral anticancer treatments have improved survival across cancer types but introduced challenges in medication adherence and symptom management.
- Trial name
- SMART pilot (NCT07073807)
- Testing
- SMART Intervention using TAPPT® for Adherence, Symptom, Financial, and Social Needs Monitoring
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of California, Irvine
Non Small Cell Lung Cancer
TEIPP Immunotherapy in Patients With NSCLC
In this multicenter, open label non-randomized phase I/II dose escalation study with extension cohort HLA-A*0201-positive patients with non small cell lung cancer (NSCLC) can be included.
- Trial name
- TEIPP (NCT05898763)
- Testing
- TEIPP24 (LRPAP7-30V-SLP vaccine in Montanide ISA-51)
- Where
- 2 sites in Netherlands
- Volunteers
- 26 people
- Sponsor
- Erasmus Medical Center
Colorectal Neoplasms
Acupuncture to Reduce Symptoms of Advanced Colorectal Cancer
This study investigates the effect of acupuncture in reducing symptom distress in adults with advanced colon cancer.
- Trial name
- NCT00034034
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Uterine Cervical Neoplasms, Ovarian Neoplasms
Effect of Outpatient Symptom Management on Gynecologic Oncology Patients Receiving Chemotherapy
To evaluate whether formal referral to The Symptom Management and Supportive Care Clinic improves symptom burden in advanced stage or recurrent gynecologic oncology chemotherapy patients compared with symptom management performed…
- Conditions
- Uterine Cervical Neoplasms, Ovarian Neoplasms, Gynecologic Neoplasms, Fallopian Tube Neoplasms
- Trial name
- NCT02786524
- Testing
- Specialized Symptom Management and Supportive Care
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- University of Michigan
Esophageal Cancer, Cancer of Gastro Esophageal Junction
Treatment of Malignant Strictures in Esophagus and Gastroesophageal Junction With Covered or Partially Covered Stent.
Self expandable stent (SEMS) constitutes the main palliative treatment in advanced esophageal cancer. The palliative effect of SEMS is immediate when it comes to relief of dysphagia.
- Conditions
- Esophageal Cancer, Cancer of Gastro Esophageal Junction, Palliative Treatment
- Trial name
- StentMig (NCT02166320)
- Testing
- Partially covered SEMS, Fully covered SEMS
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital
Cancer
Use of Heart Rate Variability (HRV) Biofeedback for Cancer Survivors
Heart rate variability biofeedback (HRV-B) is a complementary, non-pharmacologic therapy that is being tested to see if it can help cancer survivors reduce their symptoms of pain, stress, insomnia, fatigue, or depression.
- Trial name
- NCT03692624
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Prisma Health-Upstate
Sexuality, Sexual Dysfunction
Sexual Health in Patients With Hematologic Malignancies
Sexual wellbeing is an integral component of psychosocial and physical wellbeing. Cancer-related symptoms, treatment side-effects and psychosocial distress have significant impact on sexual well-being and sexual health.
- Conditions
- Sexuality, Sexual Dysfunction, Psychological, Quality of Life
- Trial name
- NCT05222282
- Testing
- Sexual Health
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Bone Metastases, Breast Cancer
Safety and Efficacy Study of Concomitant Radiotherapy and Zoledronic Acid for Bone Metastases Palliation
Zoledronic acid (Zometa) belongs to a class of drugs called bisphosphonates. Bisphosphonates are used in bone metastases to keep the cancerous lesion under control in the bone and to help prevent calcium level elevations in the…
- Conditions
- Bone Metastases, Breast Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT00264420
- Testing
- zoledronic acid
- Volunteers
- 4 people
- Sponsor
- The Cleveland Clinic
Cancer, Pediatric Cancer
Integrative Health Interventions in Symptom Management of Pediatric Patients
As healthcare demands high-quality cost-effective care and patients seek self-management strategies, integrative medicine has become more of an interest to patients, physicians, and administrators.
- Trial name
- NCT05594693
- Testing
- Questionnaire, Physical Exam
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Dermatologic Complications, Malignant Neoplasm
Menadione Topical Lotion in Treating Skin Discomfort and Psychological Distress in Patients With Cancer Receiving Panitumumab, Erlotinib Hydrochloride, or Cetuximab
This clinical trial studies menadione topical lotion in treating skin discomfort and psychological distress in patients with cancer receiving panitumumab, erlotinib hydrochloride, or cetuximab.
- Conditions
- Dermatologic Complications, Malignant Neoplasm, Pain
- Trial name
- NCT01393821
- Testing
- menadione topical lotion, questionnaire administration, management of therapy complications
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Cachexia, Depression
Computerized Questionnaires in Assessing Symptoms, Pain, Depression, and Physical Function in Patients With Metastatic and/or Advanced Locoregional Cancer
RATIONALE: A computer-based system for assessing symptoms may be effective for patients with metastatic or advanced cancer. PURPOSE: This clinical trial is studying how well computerized questionnaires work in assessing symptoms…
- Conditions
- Cachexia, Depression, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00972634
- Testing
- computer-assisted intervention, questionnaire administration, assessment of therapy complications
- Where
- Norway
- Volunteers
- 1,051 people
- Sponsor
- Norwegian University of Science and Technology
Pancreatic Cancer
PANVAC™-VF Vaccine for the Treatment of Metastatic Pancreatic Cancer After Failing a Gemcitabine-Containing Regimen
The objectives of this multi-center, randomized, controlled trial are to evaluate the safety and efficacy of PANVAC-VF in combination with Granulocyte-macrophage colony-stimulating factor (GM-CSF) versus best supportive care or…
- Trial name
- NCT00088660
- Testing
- PANVAC™-VF
- Where
- 62 sites in United States
- Volunteers
- 250 people
- Sponsor
- Therion Biologics Corporation
Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
Learning Collaborative Versus Technical Assistance in Delivering a Palliative Care Program to Patients With Advanced Cancer and Their Caregivers
This trial studies the delivery of the ENABLE palliative care program by two different methods called a Virtual Learning Collaborative or Technical Assistance for patients with advanced cancer and their caregivers.
- Conditions
- Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm
- Trial name
- NCT04062552
- Testing
- Behavioral, Psychological or Informational Intervention, Educational Intervention, Medical Examination Assessment
- Where
- 113 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Rochester NCORP Research Base
Metastatic Breast Cancer
Palliative and Oncology Care Model in Breast Cancer
The purpose of this research study is to test a new way to deliver oncology and palliative care for patients with metastatic breast cancer.
- Trial name
- NCT02730858
- Testing
- Palliative and Oncology Care, Standard Oncology Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Dehydration, Symptom Cluster
Culturally Tailored Nurse Coaching Study for Cancer Symptom Management
The purpose of the study is to see whether or not a telephone/ text message intervention, delivered by a registered nurse, is helpful in managing symptoms and can also prevent dehydration caused by chemotherapy treatment when…
- Conditions
- Dehydration, Symptom Cluster, Quality of Life, Self Efficacy
- Trial name
- NCT04874584
- Testing
- CTNSM, Standard of Care Chemotherapy Education
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Miami
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