Clinical trials: Palliative Care, Patient Care
Palliative Care, Cancer
Mobile Health Application for Family Caregivers in Home Palliative Care
Family caregivers play a central role in providing daily care for patients receiving home palliative care. However, caregiving responsibilities may lead to increased burden, stress, and difficulties in symptom management and care…
- Conditions
- Palliative Care, Cancer, Caregiver
- Trial name
- CARE-Mobile (NCT07654998)
- Testing
- Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kutahya Health Sciences University
Palliative Care
Evaluation of Toxicities in Patients Treated With Palliative Radiotherapy at Policlinico Sant Orsola of Bologna.
The aim of the study is to assess the outcome in palliative patients, particularly in terms of symptom resolution or alleviation, after radiation treatment of the various tumours analysed, in relation to the treatment setting…
- Trial name
- NCT06760806
- Where
- Italy
- Volunteers
- 7,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Opioid Use, Constipation Drug Induced
Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol
Opioid-Induced Constipation (OIC) is often associated with a compromised quality of life of patients in palliative care (PC) setting.
- Conditions
- Opioid Use, Constipation Drug Induced, Cancer
- Trial name
- NCT04294550
- Testing
- Naloxegol
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Palliative Care, Pain
A Study of Sativex® for Pain Relief in Patients With Advanced Malignancy
The purpose of this study is to determine whether Sativex® and GW-2000-02 are effective in the management of subjects with intractable cancer-related pain.
- Conditions
- Palliative Care, Pain, Cancer
- Trial name
- SPRAY (NCT00674609)
- Testing
- Sativex®, THC Alone
- Where
- United Kingdom
- Volunteers
- 177 people
- Sponsor
- Jazz Pharmaceuticals
Neoplasms Malignant, Carcinoma
Existential Distress in Patients with Advanced Cancer and Their Caregivers
Despite the potential for alleviation of existential distress through psychosocial interventions, existential concerns and their impact on health care outcomes of patients and caregivers have not yet been systematically studied.
- Conditions
- Neoplasms Malignant, Carcinoma, Palliative Care
- Trial name
- NCT04600206
- Testing
- Self-report questionnaires
- Where
- 5 sites in Germany
- Volunteers
- 800 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Quality of Life, Chronic Disease
Comprehensive Care of Children With Medical Complexity
Under the auspice of 'Specially for Children and with funding from the Seton Healthcare Family, Children's Comprehensive Care (CCC) in Austin, Texas, has developed a coordinated and integrated model of care for children with…
- Conditions
- Quality of Life, Chronic Disease, Chronic Illness
- Trial name
- NCT01834456
- Testing
- Med Complex Children Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Seton Healthcare Family
Management of Oral Care and Cancer in Palliative Situation
Oral Care and Cancer: Assessing the Contribution of Training Healthcare Teams to Support the Oral Status of Patients Hospitalized in Palliative Situation
The purpose of this study is to measure the impact of training on the practical assessment and management of the oral status of patients hospitalized in palliative situation.
- Trial name
- NCT02208908
- Testing
- Evaluation of the oral conditionand proper care
- Where
- 5 sites in France
- Volunteers
- 280 people
- Sponsor
- Centre Francois Baclesse
Neoplasms
A Psychosocial Intervention Plus Early Palliative Care in the Reduction of Depression of Advanced Cancer Patients
The purpose of this study is to determine whether a brief psychosocial intervention together with early palliative care are feasible, acceptable and effective in the reduction of depressive symptoms of patients with advanced…
- Trial name
- PREPArE (NCT02133274)
- Testing
- Brief Psychosocial Intervention, Early Palliative Care
- Where
- Brazil
- Volunteers
- 63 people
- Sponsor
- Barretos Cancer Hospital
Breathless Patients With Any Established Underlying Medical Diagnosis
Development of King's College Hospital Breathlessness Service
Breathlessness is a common, distressing symptom in advanced malignant and non malignant disease, and impacts significantly on quality of life.
- Trial name
- NCT01165034
- Testing
- Breathlessness Support Service
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- King's College London
Oncology
STEP2 vs. Routine Early Palliative Care: Randomized Noninferiority Trial
Palliative care aims to improve quality of life for people with advanced illness, and early palliative care (EPC) has been shown to benefit patients with late-stage cancer.
- Trial name
- STEP2 RNT (NCT07446660)
- Testing
- Virtual and in-person Symptom screening with Targeted Early Palliative care (STEP2), Early Palliative Care (EPC)
- Where
- Canada
- Volunteers
- 652 people
- Sponsor
- University Health Network, Toronto
Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD)
Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea
Persistent dyspnea is a debilitating symptom, that is common and difficult to treat. This symptom is found in many different diseases including chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD)…
- Conditions
- Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD), Chronic Heart Failure (CHF), COPD
- Trial name
- HYPNEA (NCT07173348)
- Testing
- Hypnosis
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University Hospital, Geneva
Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative, Cancer (Solid Tumors)
WellSpan-THRIVE Cancer QOL Study
Cancer affects millions of people worldwide and can significantly impact not only survival, but also day-to-day quality of life.
- Conditions
- Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative, Cancer (Solid Tumors), Cancer (With or Without Metastasis), Cancer - Ovarian
- Trial name
- THRIVE (NCT07433660)
- Where
- 5 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- WellSpan Health
Cancer, Heart Failure
Telepalliation - Digital Platform for Patients in Palliation and Their Relatives
This project has focus on patients in palliation testing a digital platform TelePal.dk.
- Conditions
- Cancer, Heart Failure, Chronic Obstructive Pulmonary Disease, Neurological Diseases
- Trial name
- NCT04995848
- Testing
- Telepalliation
- Where
- Denmark
- Volunteers
- 182 people
- Sponsor
- Aalborg University
Cancer, Palliative Care
Assessment of Patient Satisfaction in Palliative Cancer When They Return Home After Hospitalization in Palliative Care
The proposed work is part of a multidisciplinary approach to continuity of care in the particular context of the palliative phase of cancer.
- Conditions
- Cancer, Palliative Care, Home
- Trial name
- NCT02207543
- Testing
- Medical telephone contact
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Francois Baclesse
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Palliative Care
Randomized Controlled Trial of Group Psychotherapy Interventions for Cancer Patients
The purpose of this study is to compare two types of group counseling for cancer patients: Meaning-Centered counseling and Supportive counseling.
- Trial name
- NCT00494910
- Testing
- Meaning Centered Group Psychotherapy, Supportive Group Psychotherapy
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hospice and Palliative Care Nursing, Terminally Ill Patients
The Short-Term and Long-Term Effects of Providing Mechanical Bath in Terminally Ill Patients
Providing mechanical bathing (MB) is a commonly used strategy to maintain cleanness and comfort in patients with terminally illness. However, extra devices, costs, and human resources are required for such service.
- Trial name
- NCT06620146
- Testing
- mechanical bathing
- Where
- Taiwan
- Volunteers
- 245 people
- Sponsor
- National Taiwan University Hospital
End of Life Care, Liver Cirrhosis
Palliative Care for Patients With Liver Cirrhosis
Background: Patients with liver cirrhosis rarely receive palliative care although the Danish Health Authorities and WHO recommend it.
- Conditions
- End of Life Care, Liver Cirrhosis, Nurse-Patient Relations, Quality of Life
- Trial name
- LiverCare (NCT05431946)
- Testing
- Advance Care Planning and the consequent actions
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Acute Myeloid Leukemia
A Collaborative Palliative and Oncology Care Model for Patients With Acute Myeloid Leukemia
This research study is evaluating the impact a collaborative palliative care and oncology team will have on the quality of life, symptoms, mood, and end of life outcomes of patients with acute myeloid leukemia (AML).
- Trial name
- NCT02975869
- Testing
- Standard Leukemia Care, Palliative Care
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Cancer
ALIGN Intervention in Patients With Advanced Cancer Discharging to a SNF
This is a single arm, pre-post, pilot study assessing the feasibility and acceptability of the ALIGN intervention in metastatic adult cancer patients discharging to local area SNFs.
- Trial name
- ALIGN (NCT04882111)
- Testing
- ALIGN
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Colorado, Denver