Clinical trials: Palliative Care, Patient Care
Dementia, Dementia, Vascular
Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers
The goal of this clinical trial is to improve communication among clinicians, patients with memory problems, and their family members.
- Conditions
- Dementia, Dementia, Vascular, Mixed Dementias, Alzheimer Disease
- Trial name
- PICSI-M (NCT05596760)
- Testing
- Jumpstart Guide
- Where
- 3 sites in United States
- Volunteers
- 1,802 people
- Sponsor
- University of Washington
Palliative Care, Acute Myeloid Leukaemia
Effectiveness of Early Intervention in Palliative Care for Acute Myeloid Leukemia Patients Comparing to Standard of Care
Hemato-oncology patients undergoing intensive chemotherapy treatments experience different types of symptoms during and after treatments, which are often refractory to the established therapy.
- Trial name
- NCT06848270
- Testing
- Early palliative care integration
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
Medical Oncology, Cardiology
Results From a Health System-wide Implementation of a Quality of Life Questionnaire
The purpose of this retrospective chart review pilot study is to research the results and scores of the QOL questionnaire implemented across Allina Health clinics.
- Conditions
- Medical Oncology, Cardiology, Integrative Medicine, Physical and Rehabilitation Medicine
- Trial name
- NCT02906423
- Testing
- PROMIS-10 questionnaire
- Where
- United States
- Volunteers
- 43,000 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Cancer, Malignancies Multiple
Remote Vital Sign Monitoring in Palliative Care Patients Using a Wearable ECG Monitor
The goal of this study is the assess the use of remote monitoring of vital signs using commercially available medical devices in patients with advanced cancer admitted to a hospice inpatient unit for end-of-life care.
- Conditions
- Cancer, Malignancies Multiple, Terminal Care, Hospice
- Trial name
- VITAL-PC (NCT07512505)
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- Our Lady's Hospice and Care Services
Active Cancer, Active Cancer Treatment
STAMP+CBT mHealth for Cancer Pain
The purpose of this study is to test whether a mobile application developed to help people with cancer pain is useful and helpful to patients with cancer.
- Conditions
- Active Cancer, Active Cancer Treatment, Advanced Cancer, Palliative Care
- Trial name
- NCT05403801
- Testing
- STAMP+CBT application
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Metastatic Cancer, Palliatives Treatments
Towards an Early Integration of Palliative Care in Oncology
The primary objective of the study is to describe the nature and to estimate the prevalence the health needs of patients with metastatic cancer and their main caregivers, between the period from diagnosis to death.
- Trial name
- BESACE (NCT05339945)
- Where
- France
- Volunteers
- 361 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer, Solid Tumor
Home-Based Symptom Monitoring: Its Impact on Cancer Care Team Behaviors and Patient Outcomes
The primary research objective of this protocol is to evaluate the impact of integrating a home-based symptom monitoring system in the day-to-day care of cancer patients in community settings on the frequency of supportive…
- Conditions
- Cancer, Solid Tumor, Hematologic Malignancy
- Trial name
- NCT00300001
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Community Cancer Care
Nausea, Vomiting
Does Acupressure Help Reduce Nausea and Vomiting in Palliative Care Patients? Formal Study
Pilot study completed - power calculation performed. Now formal double blind randomized study comparing active with placebo wristbands for nausea in palliative care patients to be carried out.
- Trial name
- NCT00550251
- Testing
- Acupressure Wrist Bands (Sea-Bands)
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Sue Ryder Care
HIV
Outcomes for Antiretroviral Therapy Patients Receiving Palliative Care
Despite overwhelming need for effective HIV palliative care in sub-Saharan Africa, a systematic appraisal of the literature found almost no outcome or evaluative evidence.
- Trial name
- TOPCare (NCT01608802)
- Testing
- Palliative care, Standard care
- Where
- 2 sites in Kenya, South Africa
- Volunteers
- 240 people
- Sponsor
- King's College London
Colorectal Cancer, Bladder Cancer
Feasibility Testing of Patient Reported Outcomes - Informed Symptom Management System (PRISMS)
This is a proof-of-concept pilot randomized clinical trial to test the feasibility of the innovative Patient-Reported Outcomes-Informed Symptom Management System (PRISMS) to enhance personalized supportive care for cancer…
- Conditions
- Colorectal Cancer, Bladder Cancer, Ovarian Cancer, Cervical Cancer
- Trial name
- PRISMS (NCT04492007)
- Testing
- Patient-Reported Outcomes-Informed Symptom Management System (PRISMS)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Life-limiting Illness, Breast Cancer
Therapeutic Support to Strengthen Dignity, Mental Well-being and Quality of Life in Acute Palliative Care Patients.
The goal of this clinical trial is to test the benefit of a newly designed personalized therapeutic intervention compared to the standard specialized palliative care service at the swiss acute palliative hospital care.The main…
- Conditions
- Life-limiting Illness, Breast Cancer, Glioblastoma, Prostate Cancer
- Trial name
- NCT06549075
- Testing
- Therapeutic support, Standard Specialized Palliative Consultation Service
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- University Hospital, Basel, Switzerland
COVID-19, Palliative Care
Palliative Care in Patients With COVID-19: Analysis of Costs of Hospitalization in Wards and Intensive Care Units
The confrontation of COVID-19 foreshadowed a serious crisis of scarce health resources worldwide. To assist in this confrontation, the Palliative Care Scientific Technical Core of the Clinical Hospital, School of Medicine, Sao…
- Trial name
- NCT05897229
- Testing
- Analysis of costs with patient care during hospitalization
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
Refractory Pains
Efficiency and Safety of a Procedural Sedation by Propofol on Terminally Ill Patients With Refractory Pain
Relieving symptoms of patients hospitalized in a palliative care unit is a priority. Although they receive appropriate care, they may still experience pain refractory to analgesia or/and to conservative treatment during care…
- Trial name
- PROPOPAL2 (NCT02734511)
- Testing
- sedation with propofol
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Advanced Cancer
Psychosocial Intervention in Latino Patients with Advanced Cancer
Palliative Care focuses on symptom management and quality of life and helps patients with life-limiting illness match goals and preferences for care.
- Trial name
- NCT03763032
- Testing
- Counseling
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Colorado, Denver
Neoplasm Metastasis
Stereotactic Body Radiotherapy Followed by Surgical Stabilization for Patients With Unstable Spinal Metastases
The aim of this study is to assess the feasibility and safety of combining stereotactic body radiotherapy (SBRT) and pedicle screw fixation in a 48-hour window for the treatment of painful unstable metastases of the thoracic…
- Trial name
- BLEND (NCT02622841)
- Testing
- BLEND
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- UMC Utrecht
Advance Care Planning
Planning for Future Care With Patients With Advanced Cancer
Advance Care Planning (ACP) is a process where patients (and their families if appropriate) discuss with their doctors and nurses what may happen as their illness progresses, including how they (and their family) would like to be…
- Trial name
- NCT04499872
- Testing
- Advance Care Plan with Trajectory Touchpoint Technique
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Anxiety, Depression
PARTNER II: Improving Patient and Family Centered Care in Advanced Critical Illness
This is a stepped wedged randomized controlled trial comparing the PARTNER intervention with usual care in 5 Intensive Care Units.
- Trial name
- NCT02445937
- Testing
- PARTNER II
- Where
- 2 sites in United States
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Advanced Heart Failure, Advanced Non-Colorectal Gastrointestinal Cancer
Tier Palliative Care For Patients With Advanced Heart Failure or Cancer
TIER-PC is an adaptive model of delivering palliative care that provides the right level of care to the right patients at the right time.
- Conditions
- Advanced Heart Failure, Advanced Non-Colorectal Gastrointestinal Cancer, Advanced Lung Cancer, Advanced Triple Negative Breast Cancer
- Trial name
- TIER-PC (NCT07391956)
- Testing
- Tier-Palliative Care, Community Health Worker
- Where
- 5 sites in United States
- Volunteers
- 400 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acupressure, Cancer Pain
The Effect of Acupressure and Reiki on Pain and Fatigue Levels
This research was conducted with the aim of determining the effect of levels of pain and fatigue of acupressure and Reiki application on cancer patients receiving palliative care.
- Conditions
- Acupressure, Cancer Pain, Fatigue
- Trial name
- NCT05473845
- Testing
- Acupressure intervention, Reiki intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Mardin Artuklu University
Heart Failure, Quality of Life
Focused Palliative Care Intervention in Advanced Heart Failure
This small pilot study will be assessing the the impact of a standardized, social-worker led, longitudinal palliative care intervention on alignment of patient and physician understanding of prognosis and goals of care.
- Trial name
- NCT02805712
- Testing
- Verbal Information and Discussion, Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital