Clinical trials: Palliative Care
Palliative Care
Sodium Oxybate Versus Midazolam for Comfort Sedation
The study aims at deepen the proof level of sodium oxybate use for comfort sedation at the end of life in a palliative care unit by comparing it to midazolam in a prospective randomized study with blinded efficacy evaluation.
- Trial name
- ONAMI (NCT05085873)
- Testing
- Sodium Oxybate injection, Midazolam injection
- Where
- Monaco
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Palliative Care, Advanced Cancer
A Feasibility Study of Death Education Intervention for Family Caregivers of Advanced Cancer Patients
Advanced cancer is the leading cause of death in the world and China. Family caregivers, as the closest individuals to advanced cancer patients, suffer from a range of psychological and spiritual issues due to patients' impending…
- Conditions
- Palliative Care, Advanced Cancer, Family Caregivers
- Trial name
- NCT07367984
- Testing
- Death education intervention for family caregivers of advanced cancer patients
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Palliative Care, Withdrawal of Life Support
End-of-life Care in Mechanically Ventilated Patients: Impact of a Comprehensive Palliative Care Protocol in the Intensive Care Setting
The ARREVE-3 trial will evaluate whether a structured palliative care protocol can improve end-of-life management for mechanically ventilated ICU patients in whom a decision to withdraw life-sustaining therapies has been made.
- Conditions
- Palliative Care, Withdrawal of Life Support, Intensive Care Medicine, Sedation
- Trial name
- ARREVE-3 (NCT07368010)
- Testing
- Protocol for palliative care and life-support withdrawal
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Nantes University Hospital
Education of Primary Care Clinicians, Palliative Care
All Providers Better Communication Skills Program' (ABCs)
High quality, person-centered communication for those living with serious illness benefits patients, families and clinicians. Evidence shows that clinicians rarely engage patients in these, sometimes challenging, discussions.
- Conditions
- Education of Primary Care Clinicians, Palliative Care, Communication
- Trial name
- NCT06606470
- Testing
- All providers Better Communication Skills program' (ABCs) interprofessional provider education
- Where
- 2 sites in Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- McMaster University
Palliative Care
Impact of Medicalized Residential Care (LAM) on the Development of Care Plans for Vulnerable Patients in Palliative Care
The aim of the research is to identify the factors influencing the development of care plans for vulnerable patients admitted to medicalized care facilities (LAM) and in palliative care.
- Trial name
- LAM-SP (NCT07342985)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Palliative Care, Constipation
The Effect of Constipation Insoles on the Management of Constipation
Constipation is a common symptom among patients receiving palliative care and significantly affects their quality of life. Effective management of constipation requires both pharmacological and non-pharmacological approaches.
- Trial name
- NCT07339293
- Testing
- constipation insole, Walk
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Palliative Care
Antithrombotic Therapy at the End of Life: The PEACE Study
"Antithrombotic Therapy at the End of Life: The PEACE Study" is a multicenter, non-profit, cross-sectional observational study. In the absence of shared guidelines, therapeutic decisions on antithrombotic drugs vary significantly…
- Trial name
- PEACE (NCT07338071)
- Testing
- antithrombotic drugs
- Where
- Italy
- Volunteers
- 410 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Advance Care Planning, Palliative Care
Palliative Care Educator
The investigators propose to conduct a stepped wedge cluster randomized trial of an advance care planning (ACP) educator-led intervention among hospitalized patients aged 65 and over, or any patient with Alzheimer's Disease and…
- Conditions
- Advance Care Planning, Palliative Care, Alzheimer's Disease and Related Dementias, Doctor-patient Communication
- Trial name
- VIDEO-PCE (NCT04857060)
- Testing
- ACP Educator led, video assisted discussion
- Where
- 2 sites in United States
- Volunteers
- 11,174 people
- Sponsor
- Tufts Medical Center
Pediatric Palliative Care, Caregiver Burden
The Effect of Watson Human Care Theory and Acceptance and Commitment Therapy-Based Counseling Program Applied to Parents of Pediatric Palliative Care Patients on Value-Based Life and Care Burden
This study aims to examine the effect of Watson Human Care Theory and Acceptance and Commitment Therapy-based counseling program applied to parents of pediatric palliative care patients on value-oriented living and care burden.
- Conditions
- Pediatric Palliative Care, Caregiver Burden, Acceptance and Commitment Therapy
- Trial name
- NCT07327580
- Testing
- Counseling Program Based on Watson Human Care Theory and Acceptance and Commitment Therapy (ACT)
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Palliative Care, Health Services
Point Prevalence Survey of Palliative Care Needs in Hospitals and Residential Care Facilities for the Elderly.
The goal of this observational, point-prevalence study is to assess the burden of palliative care needs among adults hospitalised in Internal Medicine and Geriatrics wards, and among residents of long-term care facilities, on the…
- Trial name
- PCD (NCT07313748)
- Where
- 2 sites in Italy
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Malignant Neoplasm, Carcinoma
Short-term Psychodynamic Psychotherapy in Serious Physical Illness
Life-threatening physical illness may powerfully re-activate existential conflict. There is little evidence to date on the effectiveness of relationship-focused therapies in this patient group.The aim of this study is to pilot a…
- Conditions
- Malignant Neoplasm, Carcinoma, Palliative Care
- Trial name
- ORPHYS (NCT05520281)
- Testing
- Short-term psychodynamic psychotherapy for patients with serious physical illness (ORPHYS)
- Where
- 4 sites in Germany
- Volunteers
- 24 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cancer, Palliative Care, Patient Care
Virtual Versus In-Person Approaches
This randomized controlled trial evaluates the effectiveness of two models of early palliative care delivery for adults with cancer: virtual care provided through scheduled video consultations and standard in-person clinic…
- Trial name
- NCT07274904
- Testing
- Virtual Early Palliative Care, Standard In-Person Early Palliative Care
- Volunteers
- 252 people
- Sponsor
- Al Al Bayt University, Jordan
Chronic Pain, Cancer Pain
UDOPAL Study: Home-Based Interventional Approach to Pain Management in Home-Hospitalized Patients
The UDOPAL Study proposes an innovative home-based care approach for the management of pain in patients admitted to the Home Hospitalization Unit (UHD).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Palliative Care
- Trial name
- UDOPAL (NCT07265492)
- Testing
- UDOPAL model
- Volunteers
- 100 people
- Sponsor
- Hospital de Manises
Cancer, Cancer Pain
Effect of Music on Pain and Anxiety in Palliative Cancer Patients
Background: Cancer patients receiving palliative care often endure a variety of distressing symptoms, most notably pain and anxiety.
- Conditions
- Cancer, Cancer Pain, Palliative Care, Anxiety
- Trial name
- NCT07262151
- Testing
- Music Application, Procedures for the Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Karamanoğlu Mehmetbey University
Palliative Care
The MuSt-PC: a Pilot Study to Assess Symptom Burden of Co-occuring Symptoms
In this pilot study, physicians and nurse practitioners working in different care settings will use MuSt-PC, for adult patients with any life-limiting iilness, for whom the Surprise question is answered negatively: if the HCP…
- Trial name
- NCT06107946
- Testing
- USD questionnaire
- Where
- 2 sites in Netherlands
- Volunteers
- 44 people
- Sponsor
- University Medical Center Groningen
Stage IV Non-small Cell Lung Cancer, Targeted Therapy
Patient-centered, Optimal Integration of Survivorship and Palliative Care
The goal of this study is to develop and test the feasibility of a supportive care model (POISE) for patients with metastatic Non-small Cell Lung Cancer (NSCLC).
- Conditions
- Stage IV Non-small Cell Lung Cancer, Targeted Therapy, Nonsmall Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung
- Trial name
- NCT04900935
- Testing
- POISE
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Metastatic Cancer, Palliative Care
Impact of a Booklet-Question List on Cancer Patients or Their Families Seeking Prognostic Information During a Palliative Care Consultation
Prospective, randomized, multicentre phase III study to evaluate the level and type of information requested by patients or families during a palliative care consultation after they have been given the Booklet-Question List (BQL).
- Trial name
- QUEPAL (NCT02854293)
- Testing
- Booklet-Question List
- Where
- 5 sites in France
- Volunteers
- 121 people
- Sponsor
- Institut Curie
Pediatric Palliative Care
Prospective Home-Based Palliative Care and Hospice Study
The purpose of this study is to test the hypothesis that the addition of home-based hospice and palliative care (HBHPC) will provide a reduction in health care utilization, improve quality of life, and facilitate goal-concordant…
- Trial name
- NCT06362239
- Testing
- Study Surveys
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Steven Smith
Palliative Care
Pilot Study Evaluating the Therapeutic Effects of Passive Exposure Virtual Reality on Pain, Anxiety, Fatigue, and Well-being in Patients With Complex Palliative Care Needs.
The EPURAVAS "Pilot Study Using Augmented and Virtual Reality to Ease Suffering in Palliative Care" study is designed to investigate a non-medication treatment for complex symptoms in palliative care.
- Trial name
- EPURAVAS (NCT07214090)
- Testing
- Transparent Augmented Reality with Real-World Video Feed Overlay (RVAT), Passive Multisensory Virtual Reality Immersion via Head-Mounted Display (RVEP)
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Palliative Care
Enhancing Palliative Care in ICU
The aim of this study is to reduce the suffering in intensive care through palliative care consultations.
- Trial name
- NCT06605079
- Testing
- Complex intervention, Routine treatment
- Where
- 31 sites in Czechia, Germany and 3 more
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany