Clinical trials: Palliative Patients
Male Breast Cancer
Tamoxifen +/- GnRH Analogue vs Aromatase Inhibitor + GnRH Analogue in Male Breast Cancer Patients
A prospective, randomised multi-centre phase II study evaluating the adjuvant, neoadjuvant or palliative treatment with tamoxifen +/- GnRH analogue versus aromatase inhibitor + GnRH analogue in male breast cancer patients (MALE).
- Trial name
- MALE (NCT01638247)
- Testing
- Tamoxifen, Tamoxifen and GnRH analogue, Exemestane and GnRH analogue
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- GBG Forschungs GmbH
Neoplasms
Mobile Application Using the PRO-CTCAE to Improve Patients' Participation in Symptom Management During Treatment.
This study aims to evaluate the effect of a mobile application system using the Patient Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) to improve patients' participation in symptom…
- Trial name
- NCT04568278
- Testing
- ePRO-CTCAE application
- Where
- 2 sites in South Korea
- Volunteers
- 222 people
- Sponsor
- Samsung Medical Center
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasm
- Trial name
- PICSI-H (NCT04281784)
- Testing
- EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 2,512 people
- Sponsor
- University of Washington
Lung Cancer
Study of Stepped Palliative Care in Patients With Advanced Lung Cancer DF/HCC SOCIAL-BEHAVIORAL RESERACH PROTOCOL
This research study is evaluating a new way to provide palliative care to patients who have recently been diagnosed with lung cancer. .
- Trial name
- NCT03220100
- Testing
- Stepped Palliative Care
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Massachusetts General Hospital
Patient-reported Outcomes
Perioperative Symptom Study of Lung Cancer (CN-PRO-Lung 1)
Investigators propose a multicenter prospective observational cohort study to develop and validate essential technical parameters for establishing the patient-reported outcome-based perioperative symptom management cohort in…
- Trial name
- NCT03341377
- Where
- 6 sites in China
- Volunteers
- 512 people
- Sponsor
- Xiaojun Yang
Palliative Care, Heart Failure
Advanced Heart Care at Home
End-of-life (EOL) care for heart failure (HF) patients includes high healthcare utilization and costs, in part due to the lack of integration of optimal HF management and home-based palliative care.
- Conditions
- Palliative Care, Heart Failure, Health Care Utilization, Quality Improvement
- Trial name
- AHCAH (NCT03724695)
- Testing
- Clinician nudge or opt out approach for AHCAH liaison visit
- Where
- United States
- Volunteers
- 709 people
- Sponsor
- University of Pennsylvania
Bone Metastases
Lazanda in Cancer Patients Receiving Palliative Radiation
Advanced cancer patients often require palliative (pain relieving) radiotherapy to treat cancer-related symptoms. The delivery of radiation requires patients to lie still on a hard flat surface, which can result in significant…
- Trial name
- NCT03071744
- Testing
- Lazanda
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Joseph Ma
Neoplasms
Study to Identify and Measure the Values and Palliative Care Pref. of Hindu Patients and Their Caregivers
Historically, palliative care in the US has been rooted in the cultural values of a Caucasian, Christian middle class. Greater understanding of how culture influences the delivery of palliative care to minority patients is needed…
- Trial name
- NCT05538481
- Testing
- Semi-structured interview, Developed survey completion, Systems of Belief Inventory (SBI-15R)
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Cancer
Novel Palliative Care Model for Advanced Cancer Patients: A Randomized Controlled Trial Study
This is a randomized controlled trial of the 'Supportive and Palliative care Review Kit in Locations Everywhere' (SPARKLE) intervention, an outpatient-based model of early palliative care.
- Trial name
- SPARKLE2 (NCT04242251)
- Testing
- SPARKLE Model of care
- Where
- Singapore
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Acute Myeloid Leukemia
A Collaborative Palliative and Oncology Care Model for Patients With Acute Myeloid Leukemia
This research study is evaluating the impact a collaborative palliative care and oncology team will have on the quality of life, symptoms, mood, and end of life outcomes of patients with acute myeloid leukemia (AML).
- Trial name
- NCT02975869
- Testing
- Standard Leukemia Care, Palliative Care
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
End-of-life Care, Palliative Care
Outcomes of Early Palliative Care Intervention for High-Risk Patients in the Intensive Care Unit-A Pilot Study
The investigators propose to conduct a feasibility study of identifying high-risk ICU patients using previously validated integrated prediction model and employing early palliative care intervention.
- Conditions
- End-of-life Care, Palliative Care, Intensive Care Unit
- Trial name
- NCT04487054
- Testing
- Pro-active palliative care
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- West Virginia University
Dysphagia, Esophageal Cancer
Focal Cryoballoon Ablation for Malignant Dysphagia
Rationale: Dysphagia is commonly encountered in patients with esophageal carcinoma who are no candidates for treatment with curative intent. It often has a considerable impact on quality of life and can cause malnourishment.
- Conditions
- Dysphagia, Esophageal Cancer, Cryotherapy
- Trial name
- DYS-CBAS (NCT06618742)
- Testing
- Cryotherapy
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Laura Boer
Idiophatic Pulmonary Fibrosis
Palliative Care in Pulmonary Fibrosis
The investigators will examine the effect of introducing palliative in patients with end-stage idiopathic pulmonary fibrosis, refractory to the pharmacological treatment or not deemed to be treated, on patient-reported outcomes…
- Trial name
- PULFIP (NCT02929966)
- Testing
- palliative care program, standard respiratory care
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Gynecological Cancer
Investigation of the Effects of Online Education Application on Gynecological Cancer Patients Receiving Chemotherapy
The aim of the study was to examine the effect of online nursing education given to women diagnosed with gynecological cancer and receiving chemotherapy. It was conducted as a randomized controlled experimental study.
- Trial name
- NCT06574256
- Testing
- Chemotherapy symptom Management Online Education
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Manisa Celal Bayar University
Metastatic Cancer
Prospective Validation of a Points Score System Predicting 30-day Survival
This is a one-stage single-arm phase II clinical trial designed to prospectively test the survival prediction tool as developed by Lee et al on patients referred to radiation oncology for palliative treatments.
- Trial name
- NCT05100342
- Testing
- Point score prediction tool for 30-day survival
- Where
- 3 sites in United States
- Volunteers
- 214 people
- Sponsor
- Indiana University
Survivorship, Breast Cancer
The LYSA (Linking You to Support and Advice) Trial
This study's aim is to evaluate the feasibility of introducing a women's malignancy survivorship clinic incorporating symptom management through ePRO collection (complex intervention) into routine follow up care in patients with…
- Conditions
- Survivorship, Breast Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- LYSA (NCT05035173)
- Testing
- Survivorship Clinic Assessments, Survivorship Clinic Nurse Resource, Survivorship Clinic Dietitian Resource
- Where
- Ireland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College Cork
Advanced Gastric Carcinoma
Efficacy and Safety oF FErric CarboxymalTose in Patients With Advanced Gastric Cancer(EFFECT-AGC)
The main objective of this study is to evaluate the efficacy and safety of IV FCM(ferric carboxymaltose) in patients with AGC receiving palliative chemotherapy.
- Trial name
- NCT05226169
- Testing
- Ferinject, Conservative management
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Asan Medical Center
Bladder Neoplasms
Bladder Cancer Patient-Reported Outcomes
The purpose of this study is to identify aspects of the bladder cancer (BlCa) survivorship experience that differ by clinical risk at diagnosis.
- Trial name
- NCT01090388
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Baylor College of Medicine
Support, Family
The Effect of Psychoeducation on Hopelessness, Death Anxiety and Caregiver Burden
This study was conducted to determine the effect of Watson Human Caring Model-based psychoeducation given to the relatives of patients receiving palliative care on hopelessness, death anxiety and the burden of care.
- Trial name
- NCT06154759
- Testing
- Watson Human Caring Model-based psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara Medipol University
COPD
Early Palliative Care for Patients With Severe and Very Severe COPD: a Randomised Study
Chronic obstructive pulmonary disease (COPD) is a common and, despite existing treatment options, progressive lung disease. Patients with COPD often have only limited access to palliative care.
- Trial name
- NCT02223780
- Testing
- early palliative care
- Where
- Switzerland
- Volunteers
- 51 people
- Sponsor
- University Hospital, Geneva