Clinical trials: Palliative Patients, active
Acute Myeloid Leukemia, Myelodysplastic Syndromes
A Collaborative Palliative and Leukemia Care Model for Patients With AML and MDS Receiving Non-Intensive Therapy
This research study is evaluating the impact a collaborative palliative care and oncology team will have on end-of-life outcomes, quality of end-of-life care, and the quality of life, symptoms, and mood of patients with acute…
- Trial name
- NCT03310918
- Testing
- Palliative Care, Standard Leukemia care
- Where
- 2 sites in United States
- Volunteers
- 320 people
- Sponsor
- Massachusetts General Hospital
Palliative Care, Withdrawal of Life Support
End-of-life Care in Mechanically Ventilated Patients: Impact of a Comprehensive Palliative Care Protocol in the Intensive Care Setting
The ARREVE-3 trial will evaluate whether a structured palliative care protocol can improve end-of-life management for mechanically ventilated ICU patients in whom a decision to withdraw life-sustaining therapies has been made.
- Conditions
- Palliative Care, Withdrawal of Life Support, Intensive Care Medicine, Sedation
- Trial name
- ARREVE-3 (NCT07368010)
- Testing
- Protocol for palliative care and life-support withdrawal
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Nantes University Hospital
Oncology
Impact of Acupuncture and Manual Therapies on Patients' Quality-of-life in a Hospital-to-community Continuum
Oncology patients often suffer during hospitalization from pain, emotional distress, gastrointestinal symptoms, weakness, and quality of life (QoL)-related concerns.
- Trial name
- NCT06590766
- Testing
- acupressure/relaxation with acupuncture
- Where
- Israel
- Volunteers
- 520 people
- Sponsor
- Carmel Medical Center
Breast Cancer
Behavioral Pain Intervention for Older Cancer Patients
This randomized controlled trial examines a 1-session, telehealth pain coping skills training (PCST) protocol with five 15-minute maintenance calls (Brief PCST-Community) adapted for women with breast cancer in medically…
- Trial name
- NCT07300995
- Testing
- Pain Coping Skills Training (PCST)
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Weill Medical College of Cornell University
Metastatic Breast Cancer
Targeted Palliative Care Intervention for Patients With Metastatic Breast Cancer
Many people living with metastatic breast cancer face challenging symptoms and frequent medical visits. At the same time, conversations about personal goals, values, and preferences for care may not always happen as early or as…
- Trial name
- TARGET-PC (NCT06795529)
- Testing
- Palliative Care Intervention, "TARGET-PC", Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Cancer
Influence of Dietary and Palliative Care Consultation on the Quality of Life (Qol), Performance Status, and Nutritional Status of Cancer Patients in Bangladesh
Cancer patients are more likely to have malnutrition, which has been associated with poorer quality of life, higher morbidity, mortality rates, and impaired efficacy and tolerance to therapy.
- Trial name
- Consult Cancer (NCT06971263)
- Testing
- Consultation on both nutrition, and palliative care, Counselling on nutrition and healthy diet
- Where
- 3 sites in Bangladesh
- Volunteers
- 215 people
- Sponsor
- Jahangirnagar University
Pediatric Palliative Care
Analysis of the Hospital Node in the Management of Acute Events of Patients Referred to Pediatric Palliative Care
This study aims to analyze the role of the hospital node in the acute event management of pediatric patients referred to Pediatric Palliative Care.
- Trial name
- NO_SCUSE (NCT06797921)
- Where
- 7 sites in Italy
- Volunteers
- 350 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hypotestosteronism, Palliative Care
Testosterone Supplementation in Patients in Best Supportive Care: Impact on Quality of Life
This is a monocentric, single-arm prospective pilot study that will enrol hypogonadal (testosterone < 231 ng/dL) male subjects in best supportive care, with no further therapeutic options and no need for resuscitation.
- Trial name
- TestoSup (NCT07143279)
- Testing
- Sustanon 250
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Jules Bordet Institute
Advanced Malignant Solid Neoplasm
Technology-Enhanced Palliative Care for Advanced Cancer Patients
This trial investigates technology-enhanced palliative care for patients in phase I trials with cancer that has spread to other places in the body (advanced).
- Trial name
- NCT04989556
- Testing
- Interview, Palliative Therapy, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, eHealth
Mitigating Toxicity by Electronic Health Portal-mediated Interactive Monitoring of Patient-reported Side Effects
Chemotherapy induces side effects varying in severity, impacting patients' quality of life and necessitating unplanned hospital care. Patient-reported outcomes (PROs) could aid in early detection and management of side effects.
- Conditions
- Breast Cancer, eHealth, Symptom Monitoring, Self Management
- Trial name
- eChemoCoach (NCT06424054)
- Testing
- eChemoCoach
- Volunteers
- 746 people
- Sponsor
- Noordwest Ziekenhuisgroep
Sarcoma
This is a Randomized Study of Early Involvement of Palliative Care Along Side Standard Treatment Versus Standard Treatment Alone in Newly Diagnosed Patients With Advanced or Metastatic Soft Tissue Sarcoma (SARQUALITY)
The goal of this study is to learn whether early referral to palliative care improves quality of life for patients with advanced sarcoma.
- Trial name
- SARQUALITY (NCT06805669)
- Testing
- Early referral to palliative care, Standard Treatment
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- Mount Sinai Hospital, Canada
Metastatic Spinal Cord Compression
To Determine Whether it is Feasible to Treat Patients Requiring Urgent Radiotherapy Diagnosed With Metastatic Cord Compression (MSCC) on the Magnetic Resonance Linear Accelerator (MRL) in a Single Appointment and Compare it to the Standard of Care Radiotherapy Pathway
The goal of this clinical trial is to understand whether the Magnetic Resonance Linear Accelerator (MRL) could expedite Radiotherapy treatment for Metastatic Cord Compression (MSCC) by removing the need for a planning CT (pCT)…
- Trial name
- RESONATE (NCT06965101)
- Testing
- Radiotherapy to the spine in a single appointment
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- The Christie NHS Foundation Trust
Pancreatic Cancer
Early Palliative Care for Patients With Advanced Pancreatic Cancer.
Pancreatic adenocarcinoma is one of the deadliest cancers. Patients with pancreatic cancer experience marked physical suffering, psychological distress and resource-demanding care at the end-of-life.
- Trial name
- EarlyCarePan (NCT04632303)
- Testing
- Early Palliative Care
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Inna Chen, MD
Metastatic Gastro-esophageal Adenocarcinoma
Bemarituzumab in FGFR2b+ Patients With Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction, Who Failed at Least One Prior Line of Palliative Chemotherapy
The goal of this clinical trial is to evaluate if bemarituzumab in combination with different standard of care chemotherapies enhance tumor response in patients with FGFR2b-positive advanced or metastatic adenocarcinoma of the…
- Trial name
- NCT06680622
- Testing
- bemarituzumab, paclitaxel, ramucirumab, bemarituzumab, irinotecan, bemarituzumab, trifluridine/tipiracil
- Where
- 35 sites in Germany
- Volunteers
- 126 people
- Sponsor
- Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Cancer, Malignancies Multiple
Remote Vital Sign Monitoring in Palliative Care Patients Using a Wearable ECG Monitor
The goal of this study is the assess the use of remote monitoring of vital signs using commercially available medical devices in patients with advanced cancer admitted to a hospice inpatient unit for end-of-life care.
- Conditions
- Cancer, Malignancies Multiple, Terminal Care, Hospice
- Trial name
- VITAL-PC (NCT07512505)
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- Our Lady's Hospice and Care Services
Malignant Solid Neoplasm, Malignant Head and Neck Neoplasm
Symptom Management to Improve Completion of Patient-reported Outcome Measures
In this clinical trial, patient reported outcome (PRO) assessment completion is compared between patients (undergoing systemic therapy for head and neck or lung cancer) who receive additional symptoms monitoring and…
- Conditions
- Malignant Solid Neoplasm, Malignant Head and Neck Neoplasm, Malignant Lung Neoplasm
- Trial name
- NCT07723495
- Testing
- Monitoring of PROMIS symptoms and physical function, Monitoring of additional symptoms and symptom self-management
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Henry Ford Health System
Cancer, Fatigue
The Effect of Progressive Muscle Relaxation and Deep Breathing Exercises Applied to Palliative Care Cancer Patients on Dyspnea, Fatigue, and Self-Care Behaviors
The purpose of this study is to evaluate the effects of Progressive Muscle Relaxation (PMR) exercises and deep breathing exercises on dyspnea, fatigue, and self-care behaviors among cancer patients receiving palliative care.
- Conditions
- Cancer, Fatigue, Palliative Care, Progressive Muscle Relaxation
- Trial name
- NCT07619209
- Testing
- Progressive Muscle Relaxation, Deep Breathing Exercises
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara University
Solid Tumor, Solid Tumor, Adult
Adapting for Latinx Populations an Intervention That Involves Discussing and Sharing Patients' Health-Related Values
The purpose of this study is to translate and tailor for Latinx participants a program called Communicating with Oncology Nurses about Values from the Outset (CONVO).
- Conditions
- Solid Tumor, Solid Tumor, Adult, Solid Tumor, Unspecified, Adult
- Trial name
- NCT04942717
- Testing
- CONVO intervention
- Where
- 5 sites in United States
- Volunteers
- 234 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bone Metastases in Subjects With Advanced Cancer, Radiotherapy
Timely Integration of Palliative Care in Oncology Care for Patients Referred for Palliative Radiotherapy on Bone Metastases: A Randomized Trial
Rationale: With improvements in systemic tumour-directed treatments for primary tumours, survival rates for patients with bone metastases are improving.
- Trial name
- TIPZO-RT (NCT06805396)
- Testing
- Palliative Care Consult
- Where
- 5 sites in Netherlands
- Volunteers
- 246 people
- Sponsor
- Roxanne Gal
Machine Learning, Cardiovascular Outcome
PACT Involvement in Cardiology Patients
The goal of this trial is to determine the effectiveness of a machine-learning (ML) model predicting a serious cardiac event within the next three months, when compared pre- versus post-deployment, in pediatric cardiac…
- Conditions
- Machine Learning, Cardiovascular Outcome, Pediatric Palliative Care, Pediatric Cardiology
- Trial name
- NCT06886529
- Testing
- ML-based intervention
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- The Hospital for Sick Children