Clinical trials: Palmar Hyperhidrosis
Hyperhidrosis
20% Alcohol With Steroid Local Anesthetic Technique Versus Steroid Local Anesthetic Technique Only in Stellate Ganglion Injection in Idiopathic Palmar Hyperhydrosis
Palmar hyperhidrosis is a medical condition characterized by excessive sweating specifically from the palms of the hands. This condition can significantly impact an individual's quality of life, leading to social embarrassment…
- Trial name
- NCT07788326
- Testing
- Group A, Group B
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Hyperhidrosis Primary Focal Palms
Effect of TENS on Patients With Palmar Hyperhidrosis
To investigate the effectiveness of Transcutaneous Electrical Nerve Stimulation on Hyperhidrosis Severity on patients with primary Palmar Hyperhidrosis.
- Trial name
- NCT06532045
- Testing
- Transcutaneous electrical nerve stimulation
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hyperhidrosis, Children, Adolescents
Thoracoscopic Sympathetic Chain Interruption for Palmar Hyperhidrosis in Patients Below 18
In this study, the investigators aim to present fifteen years' experience of thoracoscopic sympathetic chain interruption for primary palmar hyperhidrosis in children and adolescents; evaluation of 3 different techniques…
- Conditions
- Hyperhidrosis, Children, Adolescents, Thoracoscopic Sympathetic Chain Interruption, Sympathetic Disorder
- Trial name
- MISforPPH (NCT06113978)
- Testing
- Thoracoscopic sympathectomy, Thoracoscopic sympathotomy, Thoracoscopic sympathetic chain clipping
- Where
- Egypt
- Volunteers
- 420 people
- Sponsor
- dr. Muhammad Abdelhafez Mahmoud, MD
Palmar Hyperhidrosis
Severe Primary Hand Hyperhidrosis Treatment With Topical Administration of Victorhy
The objective of this study is to assess the efficacy and safety of Victorhy, a topical TTB gel in patients with severe primary hand hyperhidrosis.
- Trial name
- NCT06645509
- Testing
- TTB gel (dose 1), TTB gel (dose 2)
- Where
- 4 sites in Spain
- Volunteers
- 58 people
- Sponsor
- Dryox Health
Hyperhidrosis
A Study to Evaluate Clinical Effect, Pharmacokinetics , Safety, and Tolerability of Umeclidinium in Palmar Hyperhidrosis Subjects
Umeclidinium (UMEC) is a potent pan-active long-acting muscarinic antagonist (LAMA). It is anticipated that topical administration of UMEC will block stimulation of muscarinic receptors, thereby reducing the overproduction of…
- Trial name
- NCT02673619
- Testing
- Umeclidinium, Vehicle
- Where
- 6 sites in United States, Canada
- Volunteers
- 58 people
- Sponsor
- Stiefel, a GSK Company
Hyperhidrosis, Hyperhidrosis Palmaris et Plantaris
Management of Palmar Hyperhidrosis With Hydrogel-based Iontophoresis
This study will evaluate the use of hydrogel electrode pads (rather than tap water baths) to deliver iontophoresis treatment using a traditional iontophoresis device.
- Trial name
- NCT02854540
- Testing
- Hydrogel electrode-based iontophoresis
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Primary Palmar Hyperhydrosis
Bilateral Endoscopic Thoracic T3 Sympathectomy Versus T3 Radiofrequency Ablation for Primary Palmar Hyperhidrosis
Primary hyperhidrosis disease is characterized by much more sweating above the needs for thermoregulation, which is worsen by increased temperature and emotional factors it can be seen in the palms of the hands, soles of the…
- Trial name
- NCT05737914
- Testing
- Endoscopic thoracic T3 sympathectomy, ThoracicT3 radiofrequency ablation
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Ain Shams University
Hyperhidrosis
Botulinum Toxin Treatment in Craniofacial, Inguinal, Palmar, Plantar and Truncal Hyperhidrosis
Hyperhidrosis is defined as excessive sweating and affects about 2.8 % of the population. It has been shown to have a deleterious effect on the quality of life measured using the Dermatology Life Quality Index (DLQI) which is one…
- Trial name
- NCT01930604
- Testing
- Botox (onabotulinumtoxinA), NeuroBloc/Myobloc (rimabotulinumtoxinB)
- Where
- Sweden
- Volunteers
- 588 people
- Sponsor
- Carl Swartling
Palmar Hyperhidrosis
Exploratory Study to Assess the Efficacy and Safety of TC-5214 in the Treatment of Subjects With Palmar Hyperhidrosis
This is a pilot exploratory study to evaluate the safety and efficacy of TC-5214 in subjects with palmar hyperhidrosis.
- Trial name
- NCT03404570
- Testing
- Dexmecamylamine HCl
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Atacama Therapeutics
Hyperhidrosis
Cardiac Autonomic Changes After Endoscopic Thoracic Sympathectomy For Essential Palmar Hyperhidrosis
Essential palmar hyperhidrosis (EPH) is a pathological condition of excessive sweating of the hands due to an unexplained over-activity of the T2 and T3 sympathetic fibers.
- Trial name
- NCT02733497
- Testing
- Sympathectomy, Sympathicotomy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Hyperhidrosis, Quality of Life
Objective Evaluation of Patients With Palmar Hyperhidrosis Submitted to Two Levels of Sympathectomy: T3 and T4.
Compare the results obtained with video-assisted sympathectomy performed in two distinct levels ganglionic (third versus fourth thoracic ganglion) for the treatment of palmar hyperhidrosis, through a blind randomized clinical…
- Trial name
- NCT01140659
- Testing
- Video-assisted sympathectomy
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Palmar Hyperhidrosis
Unilateral Sequential Sympathectomy for Palmar Hyperhidrosis
Comparison between unilateral sequential and bilateral simultaneous endoscopic thoracic sympathectomy for palmar hyperhidrosis on patients outcomes notably compensatory hyperhidrosis.
- Trial name
- ETS (NCT02321332)
- Testing
- bilateral simultaneous endoscopic thoracic symapthectomy, unilateral sequential endoscopic thoracic symapthectomy.
- Volunteers
- 400 people
- Sponsor
- Tmaer Youssef Mohamed
Palmar Hyperhidrosis
A Study of Glycopyrronium Cloth, 2.4% in Patients With Palmar Hyperhidrosis
The objective of this study is to assess the efficacy and safety of glycopyrronium cloth, 2.4% when used to treat palmar hyperhidrosis.
- Trial name
- NCT03880266
- Testing
- Glycopyrronium cloth, 2.4%, Vehicle
- Where
- 7 sites in United States
- Volunteers
- 72 people
- Sponsor
- Journey Medical Corporation
Palmar Hyperhidrosis, Hyperhidrosis
An Open Label Study for Palmar Hyperhydrosis
The purpose of this open-label study is to evaluate the efficacy and safety of different methods of application of glycopyrronium cloth, 2.4% in patients with palmar hyperhidrosis
- Conditions
- Palmar Hyperhidrosis, Hyperhidrosis, Sweat Gland Diseases, Skin Diseases
- Trial name
- NCT04906655
- Testing
- Glycopyrronium 2.4 % Medicated Cloth
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pariser, Robert J., M.D.
Palmar Hyperhidrosis
Stellate Ganglion Block Versus Oral Medication in Treatment of Palmar Hyperhidrosis
The aim of the study is to compare between ganglion block versus combined oral anticholinergic and antidepressant drugs on treatment of palmar hyperhidrosis
- Trial name
- NCT06731101
- Testing
- Bupivacaine + Lidocaine +dexamethasone, Tryptizole + Librax
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Hyperhidrosis Due to Autonomic Dysregulation (Disorder)
Extended Versus Limited Thoracoscopic Sympathectomy: Its Impact on Palmar and Plantar Hyperhidrosis
Conclusions: In the context of palmar and plantar hyperhidrosis, extended thoracoscopic sympathectomy seemed to be preferred over limited thoracoscopic sympathectomy due to better overall outcomes and minimal time for hospital…
- Trial name
- NCT06219655
- Testing
- thoracoscopic sympathectomy
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Hyperhidrosis, Palmar Hyperhidrosis
Clinical Study to Assess the Efficacy and Safety of AT-5214 in the Treatment of Subjects With Palmar Hyperhidrosis
This is a multicenter, randomized, double-blind, placebo-controlled, parallel group comparison study of AT-5214 in subjects with moderate to severe primary palmar hyperhidrosis (sweaty palms).
- Trial name
- NCT04263623
- Testing
- Dexmecamylamine HCl
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Atacama Therapeutics
Hyperhidrosis
A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 Gel in Subjects With Palmar Hyperhidrosis
To assess the safety and local tolerability of BBI-4000 15% gel compared with vehicle (placebo) when applied topically once daily in subjects with palmar hyperhidrosis.
- Trial name
- NCT02682238
- Testing
- BBI-4000, 15%, Vehicle gel
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Botanix Pharmaceuticals
Hyperhidrosis
The Use of Microneedles With Topical Botulinum Toxin for Treatment of Palmar Hyperhidrosis
Hyperhidrosis or sweating of palms results from the overactivity of sweat glands and leads to psychosocial impairment with reduction in quality of life in those that are affected.
- Trial name
- NCT03203174
- Testing
- Microneedle, Botulinum Toxin Type A, Saline
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hyperhidrosis
The Use of Topical Oxybutynin 10% for Treating Primary Focal Hyperhidrosis-axillary, Palmar and Plantar.
Primary focal hyperhidrosis interferes with daily activities. Limited efficacy, costs, side effects and complications are issues of concern for most current therapeutic modalities.
- Trial name
- NCT02973659
- Testing
- Oxybutynin
- Volunteers
- 61 people
- Sponsor
- Tel-Aviv Sourasky Medical Center